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Conserved domains on  [gi|2769572674|ref|WP_366495006|]
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MULTISPECIES: nuclear transport factor 2 family protein [unclassified Streptomyces]

Protein Classification

nuclear transport factor 2 family protein( domain architecture ID 10007626)

nuclear transport factor 2 (NTF2) family protein with a SnoaL-like polyketide cyclase domain

CATH:  3.10.450.50
SCOP:  4001306|3000472

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-114 1.51e-08

Ketosteroid isomerase-related protein [General function prediction only];


:

Pssm-ID: 442849  Cd Length: 126  Bit Score: 49.54  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2769572674   1 MRAFREAVEAQDMDAVEALLAEDVVFTSPV--VFKPYPGKAITAAILHGVARVFEDFRYVREIGDPDGSDSALMFAARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2769572674  79 DR------ELTGCDFIHVdEEGLIDELTVMVRPLSGAQALQA 114
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKIVRVREYFDTAALAAALGA 126
 
Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-114 1.51e-08

Ketosteroid isomerase-related protein [General function prediction only];


Pssm-ID: 442849  Cd Length: 126  Bit Score: 49.54  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2769572674   1 MRAFREAVEAQDMDAVEALLAEDVVFTSPV--VFKPYPGKAITAAILHGVARVFEDFRYVREIGDPDGSDSALMFAARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2769572674  79 DR------ELTGCDFIHVdEEGLIDELTVMVRPLSGAQALQA 114
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKIVRVREYFDTAALAAALGA 126
SnoaL_2 pfam12680
SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.
 2-96 1.18e-04

SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.


Pssm-ID: 432716 [Multi-domain]  Cd Length: 100  Bit Score: 38.42  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2769572674   2 RAFREAVEAQDMDAVEALLAEDVVFTSPvvFKPYPGKAITAAILHGVARVFEDFRYVREIGDPDGSDSALMFAARVGDR- 80
Cdd:pfam12680   2 RRFYEALNAGDLDALAALFAPDAVFHDP--GGPLRGRDAIRAFFAALFAAFPDLRFEIHDVIADGDRVAVRWTVTGTIPp 79

                          90       100
                  ....*....|....*....|.
gi 2769572674  81 -----ELTGCDFIHVdEEGLI 96
Cdd:pfam12680  80 tgrgvRVRGVDVFRF-RDGKI 99
TIGR02096 TIGR02096
conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about ...
 2-55 1.74e-04

conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about 135 amino acids in length largely restricted to the Proteobacteria. This family and a delta5-3-ketosteroid isomerase from Pseudomonas testosteroni appear homologous, especially toward their respective N-termini. Members, therefore, probably are enzymes.


Pssm-ID: 273970  Cd Length: 129  Bit Score: 38.51  E-value: 1.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2769572674   2 RAFREAVEAQDMDAVEALLAEDVVFTSPVVFKPYPGKAITAAILHGVARVFEDF 55
Cdd:TIGR02096   5 QHWIEAFNRGDMDAVLALLAEDVLYDDNQGGRVLGGKAQLARFLAPYRTAFPDL 58
 
Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-114 1.51e-08

Ketosteroid isomerase-related protein [General function prediction only];


Pssm-ID: 442849  Cd Length: 126  Bit Score: 49.54  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2769572674   1 MRAFREAVEAQDMDAVEALLAEDVVFTSPV--VFKPYPGKAITAAILHGVARVFEDFRYVREIGDPDGSDSALMFAARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2769572674  79 DR------ELTGCDFIHVdEEGLIDELTVMVRPLSGAQALQA 114
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKIVRVREYFDTAALAAALGA 126
SnoaL_2 pfam12680
SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.
 2-96 1.18e-04

SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.


Pssm-ID: 432716 [Multi-domain]  Cd Length: 100  Bit Score: 38.42  E-value: 1.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2769572674   2 RAFREAVEAQDMDAVEALLAEDVVFTSPvvFKPYPGKAITAAILHGVARVFEDFRYVREIGDPDGSDSALMFAARVGDR- 80
Cdd:pfam12680   2 RRFYEALNAGDLDALAALFAPDAVFHDP--GGPLRGRDAIRAFFAALFAAFPDLRFEIHDVIADGDRVAVRWTVTGTIPp 79

                          90       100
                  ....*....|....*....|.
gi 2769572674  81 -----ELTGCDFIHVdEEGLI 96
Cdd:pfam12680  80 tgrgvRVRGVDVFRF-RDGKI 99
TIGR02096 TIGR02096
conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about ...
 2-55 1.74e-04

conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about 135 amino acids in length largely restricted to the Proteobacteria. This family and a delta5-3-ketosteroid isomerase from Pseudomonas testosteroni appear homologous, especially toward their respective N-termini. Members, therefore, probably are enzymes.


Pssm-ID: 273970  Cd Length: 129  Bit Score: 38.51  E-value: 1.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2769572674   2 RAFREAVEAQDMDAVEALLAEDVVFTSPVVFKPYPGKAITAAILHGVARVFEDF 55
Cdd:TIGR02096   5 QHWIEAFNRGDMDAVLALLAEDVLYDDNQGGRVLGGKAQLARFLAPYRTAFPDL 58
LimA COG4308
Limonene-1,2-epoxide hydrolase LimA/EphG [Secondary metabolites biosynthesis, transport and ...
 2-57 1.81e-03

Limonene-1,2-epoxide hydrolase LimA/EphG [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443449  Cd Length: 119  Bit Score: 35.65  E-value: 1.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2769572674   2 RAFREAVEAQDMDAVEALLAEDVVFTsPVVFKPYPGKAITAAILHGVARVFEDFRY 57
Cdd:COG4308     9 RAFLAAWSRLDVDAALSLLADDAVYH-NVPLPPVRGRDAVRAFLEGFLRGAAGFEV 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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