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Conserved domains on  [gi|2784009791|ref|WP_369334896|]
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glycosyltransferase [Demequina sp. B12]

Protein Classification

glycosyltransferase family protein( domain architecture ID 56)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glycosyltransferase_GTB-type super family cl10013
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 6-341 1.59e-32

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


The actual alignment was detected with superfamily member cd03798:

Pssm-ID: 471961 [Multi-domain]  Cd Length: 376  Bit Score: 129.04  E-value: 1.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791   6 VVTPWFATPDAPFAGAFVAEWTRSLGLppnEVLIVHLRS-VPLGSPTSPVTREHELARVLEIPV--AVSPEWHRARIARL 82
Cdd:cd03798     3 ILTNIYPNANSPGRGIFVRRQVRALSR---RGVDVEVLApAPWGPAAARLLRKLLGEAVPPRDGrrLLPLKPRLRLLAPL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  83 HAEALAK-HAPDEYWHAKVVHAHVGLPTGYAVAQNKPR-GARLISIEHAT----FMRKKIRddegRAAYRTLLEASDLLL 156
Cdd:cd03798    80 RAPSLAKlLKRRRRGPPDLIHAHFAYPAGFAAALLARLyGVPYVVTEHGSdinvFPPRSLL----RKLLRWALRRAARVI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 157 CAGDSEARILRAVFPSeRTKIRAVGNPIDTTVFAPNDDHSRRPLDRW--LYVGYFVPVKGVDRLINLYSQWRAANGRSfg 234
Cdd:cd03798   156 AVSKALAEELVALGVP-RDRVDVIPNGVDPARFQPEDRGLGLPLDAFviLFVGRLIPRKGIDLLLEAFARLAKARPDV-- 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 235 ELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPE 314
Cdd:cd03798   233 VLLIVGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIP 312

                         330       340
                  ....*....|....*....|....*..
gi 2784009791 315 ETmavaVESGDALLLAPEaqhGDIDRI 341
Cdd:cd03798   313 EV----VGDPETGLLVPP---GDADAL 332
 
Name Accession Description Interval E-value
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 6-341 1.59e-32

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 129.04  E-value: 1.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791   6 VVTPWFATPDAPFAGAFVAEWTRSLGLppnEVLIVHLRS-VPLGSPTSPVTREHELARVLEIPV--AVSPEWHRARIARL 82
Cdd:cd03798     3 ILTNIYPNANSPGRGIFVRRQVRALSR---RGVDVEVLApAPWGPAAARLLRKLLGEAVPPRDGrrLLPLKPRLRLLAPL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  83 HAEALAK-HAPDEYWHAKVVHAHVGLPTGYAVAQNKPR-GARLISIEHAT----FMRKKIRddegRAAYRTLLEASDLLL 156
Cdd:cd03798    80 RAPSLAKlLKRRRRGPPDLIHAHFAYPAGFAAALLARLyGVPYVVTEHGSdinvFPPRSLL----RKLLRWALRRAARVI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 157 CAGDSEARILRAVFPSeRTKIRAVGNPIDTTVFAPNDDHSRRPLDRW--LYVGYFVPVKGVDRLINLYSQWRAANGRSfg 234
Cdd:cd03798   156 AVSKALAEELVALGVP-RDRVDVIPNGVDPARFQPEDRGLGLPLDAFviLFVGRLIPRKGIDLLLEAFARLAKARPDV-- 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 235 ELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPE 314
Cdd:cd03798   233 VLLIVGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIP 312

                         330       340
                  ....*....|....*....|....*..
gi 2784009791 315 ETmavaVESGDALLLAPEaqhGDIDRI 341
Cdd:cd03798   313 EV----VGDPETGLLVPP---GDADAL 332
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 204-359 1.70e-21

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 91.18  E-value: 1.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 204 LYVGYFVPVKGVDRLINLYSQWRAANGRSFgeLVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLV 283
Cdd:pfam00534   6 LFVGRLEPEKGLDLLIKAFALLKEKNPNLK--LVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIADVFV 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2784009791 284 HLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI-DRILDFERNlPESMDSMVLNG 359
Cdd:pfam00534  84 LPSRYEGFGIVLLEAMACGLPVIASDVGGPPEV----VKDGETGFLVKPNNAEALaEAIDKLLED-EELRERLGENA 155
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 275-359 4.30e-08

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 51.91  E-value: 4.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 275 AMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI-DRILDFERNlPESMD 353
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEV----IEDGETGLLVPPGDPEALaEAILRLLED-PELRR 91


                  ....*.
gi 2784009791 354 SMVLNG 359
Cdd:COG0438    92 RLGEAA 97
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 146-339 1.14e-05

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 48.17  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 146 RTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDTTVFAP-----------NDDHSRRPLdrWLYVGYFVPVKG 214
Cdd:PLN02871  200 RFLHRAADLTLVTSPALGKELEAAGVTAANRIRVWNKGVDSESFHPrfrseemrarlSGGEPEKPL--IVYVGRLGAEKN 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 215 VDRLINLYSQWRAANgrsfgeLVLAGMGPLEEELRGIAASSPyadeIKFVGPLQRVAVARAMREADVLVHLSQHETFGVT 294
Cdd:PLN02871  278 LDFLKRVMERLPGAR------LAFVGDGPYREELEKMFAGTP----TVFTGMLQGDELSQAYASGDVFVMPSESETLGFV 347

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2784009791 295 VVEAAITGLPVISTRCGGPEETMAVAVESGDALLLAPeaqhGDID 339
Cdd:PLN02871  348 VLEAMASGVPVVAARAGGIPDIIPPDQEGKTGFLYTP----GDVD 388
sucrsPsyn_pln TIGR02468
sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this ...
 289-313 2.08e-03

sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this family are sucrose-phosphate synthases of plants. This enzyme is known to exist in multigene families in several species of both monocots and dicots. The N-terminal domain is the glucosyltransferase domain. Members of this family also have a variable linker region and a C-terminal domain that resembles sucrose phosphate phosphatase (SPP) (EC 3.1.3.24) (see TIGR01485), the next and final enzyme of sucrose biosynthesis. The SPP-like domain likely serves a binding and not a catalytic function, as the reported SPP is always encoded by a distinct protein.


Pssm-ID: 274147 [Multi-domain]  Cd Length: 1050  Bit Score: 41.30  E-value: 2.08e-03
                           10        20
                   ....*....|....*....|....*
gi 2784009791  289 ETFGVTVVEAAITGLPVISTRCGGP 313
Cdd:TIGR02468  582 EPFGLTLIEAAAHGLPMVATKNGGP 606
 
Name Accession Description Interval E-value
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 6-341 1.59e-32

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 129.04  E-value: 1.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791   6 VVTPWFATPDAPFAGAFVAEWTRSLGLppnEVLIVHLRS-VPLGSPTSPVTREHELARVLEIPV--AVSPEWHRARIARL 82
Cdd:cd03798     3 ILTNIYPNANSPGRGIFVRRQVRALSR---RGVDVEVLApAPWGPAAARLLRKLLGEAVPPRDGrrLLPLKPRLRLLAPL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  83 HAEALAK-HAPDEYWHAKVVHAHVGLPTGYAVAQNKPR-GARLISIEHAT----FMRKKIRddegRAAYRTLLEASDLLL 156
Cdd:cd03798    80 RAPSLAKlLKRRRRGPPDLIHAHFAYPAGFAAALLARLyGVPYVVTEHGSdinvFPPRSLL----RKLLRWALRRAARVI 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 157 CAGDSEARILRAVFPSeRTKIRAVGNPIDTTVFAPNDDHSRRPLDRW--LYVGYFVPVKGVDRLINLYSQWRAANGRSfg 234
Cdd:cd03798   156 AVSKALAEELVALGVP-RDRVDVIPNGVDPARFQPEDRGLGLPLDAFviLFVGRLIPRKGIDLLLEAFARLAKARPDV-- 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 235 ELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPE 314
Cdd:cd03798   233 VLLIVGDGPLREALRALAEDLGLGDRVTFTGRLPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIP 312

                         330       340
                  ....*....|....*....|....*..
gi 2784009791 315 ETmavaVESGDALLLAPEaqhGDIDRI 341
Cdd:cd03798   313 EV----VGDPETGLLVPP---GDADAL 332
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 40-338 1.75e-31

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 125.73  E-value: 1.75e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  40 VHLRSVPLGSPTSPVTREHELARVLEIPVAVSPEWHRARIARLHAEALAKHaPDeywhakVVHAHVGLPTGYAVAQNKPR 119
Cdd:cd03801    32 HDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRARRLLRELRPLLRLRK-FD------VVHAHGLLAALLAALLALLL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 120 GARLISIEHATFMRKKIRDDEGR----AAYRTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDTTVFAPNDDH 195
Cdd:cd03801   105 GAPLVVTLHGAEPGRLLLLLAAErrllARAEALLRRADAVIAVSEALRDELRALGGIPPEKIVVIPNGVDLERFSPPLRR 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 196 SRRPLD---RWLYVGYFVPVKGVDRLINLYSQWRAANGRSfgELVLAGM-GPLEEELRGIAASSpyADEIKFVGPLQRVA 271
Cdd:cd03801   185 KLGIPPdrpVLLFVGRLSPRKGVDLLLEALAKLLRRGPDV--RLVIVGGdGPLRAELEELELGL--GDRVRFLGFVPDEE 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2784009791 272 VARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI 338
Cdd:cd03801   261 LPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVATDVGGLPEV----VEDGEGGLVVPPDDVEAL 323
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 87-343 9.43e-31

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 123.24  E-value: 9.43e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  87 LAKHAPDeywhakVVHAHVGLPTgYAVAQNKPRGARLISIEHaTFMRKKIRDDEGRAAYRTLLEASDLLLCAGDSEARIL 166
Cdd:cd03811    79 LKRAKPD------VVISFLGFAT-YIVAKLAAARSKVIAWIH-SSLSKLYYLKKKLLLKLKLYKKADKIVCVSKGIKEDL 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 167 RAVFPSERTKIRAVGNPID--TTVFAPNDDHSRRPLDRW--LYVGYFVPVKGVDRLINLYSQWRAANGRSfgELVLAGMG 242
Cdd:cd03811   151 IRLGPSPPEKIEVIYNPIDidRIRALAKEPILNEPEDGPviLAVGRLDPQKGHDLLIEAFAKLRKKYPDV--KLVILGDG 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 243 PLEEELRGIAASSPYADEIKFVGplQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEEtmavAVE 322
Cdd:cd03811   229 PLREELEKLAKELGLAERVIFLG--FQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPRE----ILD 302

                         250       260
                  ....*....|....*....|.
gi 2784009791 323 SGDALLLAPEAQHGDIDRILD 343
Cdd:cd03811   303 DGENGLLVPDGDAAALAGILA 323
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 204-359 1.70e-21

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 91.18  E-value: 1.70e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 204 LYVGYFVPVKGVDRLINLYSQWRAANGRSFgeLVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLV 283
Cdd:pfam00534   6 LFVGRLEPEKGLDLLIKAFALLKEKNPNLK--LVIAGDGEEEKRLKKLAEKLGLGDNVIFLGFVSDEDLPELLKIADVFV 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2784009791 284 HLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI-DRILDFERNlPESMDSMVLNG 359
Cdd:pfam00534  84 LPSRYEGFGIVLLEAMACGLPVIASDVGGPPEV----VKDGETGFLVKPNNAEALaEAIDKLLED-EELRERLGENA 155
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 139-360 2.10e-18

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 87.68  E-value: 2.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 139 DEGRAAYRTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDTTVFAPNDDHSRR------PLDRW--LYVGYFV 210
Cdd:cd03800   151 SLRITAEEQILEAADRVIASTPQEADELISLYGADPSRINVVPPGVDLERFFPVDRAEARrarlllPPDKPvvLALGRLD 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 211 PVKGVDRLINLYSQWRAANGRsfGELVLAGmGPL-------EEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLV 283
Cdd:cd03800   231 PRKGIDTLVRAFAQLPELREL--ANLVLVG-GPSddplsmdREELAELAEELGLIDRVRFPGRVSRDDLPELYRAADVFV 307

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2784009791 284 HLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI-DRILDFERNlPESMDSMVLNGL 360
Cdd:cd03800   308 VPSLYEPFGLTAIEAMACGTPVVATAVGGLQDI----VRDGRTGLLVDPHDPEALaAALRRLLDD-PALWQRLSRAGL 380
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 84-339 4.04e-17

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 83.27  E-value: 4.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  84 AEALAKHAPDeywhakVVHAHVGLPTGYAVAQNKPRGARLISIEH---ATFMRKKIRDDEGRAAYRTLLEA-----SDLL 155
Cdd:cd05844    74 LGGAAGLAPA------LVHAHFGRDGVYALPLARALGVPLVVTFHgfdITTSRAWLAASPGWPSQFQRHRRalqrpAALF 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 156 LCAGDS-EARILRAVFPSERTKIRAVGnpIDTTVFAPNDDHSRRPldRWLYVGYFVPVKGVDRLINLYSQWRAANGRSfg 234
Cdd:cd05844   148 VAVSGFiRDRLLARGLPAERIHVHYIG--IDPAKFAPRDPAERAP--TILFVGRLVEKKGCDVLIEAFRRLAARHPTA-- 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 235 ELVLAGMGPLEEELRGIAASspyADEIKFVGPLQRVAVARAMREADVLVHLSQ------HETFGVTVVEAAITGLPVIST 308
Cdd:cd05844   222 RLVIAGDGPLRPALQALAAA---LGRVRFLGALPHAEVQDWMRRAEIFCLPSVtaasgdSEGLGIVLLEAAACGVPVVSS 298

                         250       260       270
                  ....*....|....*....|....*....|.
gi 2784009791 309 RCGGPEEtmavAVESGDALLLAPEaqhGDID 339
Cdd:cd05844   299 RHGGIPE----AILDGETGFLVPE---GDVD 322
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 145-359 5.66e-17

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 82.64  E-value: 5.66e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 145 YRTLLEASDLLLCAGDSE-ARILRAVFPSERTKIRAVGNPIDTTVFAPNDDHSRRPLDRWLYVGYFVPVKGVDRLINL-- 221
Cdd:cd03808   133 EKLALLFTDKVIFVNEDDrDLAIKKGIIKKKKTVLIPGSGVDLDRFQYSPESLPSEKVVFLFVARLLKDKGIDELIEAak 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 222 -----YSQWRaangrsfgeLVLAGMGPLEEELRGIAASSPYADEIKFVGplQRVAVARAMREADVLVHLSQHETFGVTVV 296
Cdd:cd03808   213 ilkkkGPNVR---------FLLVGDGELENPSEILIEKLGLEGRIEFLG--FRSDVPELLAESDVFVLPSYREGLPRSLL 281

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2784009791 297 EAAITGLPVISTRCGGPEEtmavAVESGDALLLAPEAQHGDI-DRILDFERNlPESMDSMVLNG 359
Cdd:cd03808   282 EAMAAGRPVITTDVPGCRE----LVIDGVNGFLVPPGDVEALaDAIEKLIED-PELRKEMGEAA 340
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 101-334 2.42e-16

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 81.26  E-value: 2.42e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 101 VHAHVGLPTGYAVAQNKPRGARLI-----SIEHATFMRKKIRDdegrAAYRTLLE-----ASDLLLCAGDSEARILRAVF 170
Cdd:cd03821    96 IHGVWTYTSLAACKLARRRGIPYVvsphgMLDPWALQQKHWKK----RIALHLIErrnlnNAALVHFTSEQEADELRRFG 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 171 PseRTKIRAVGNPIDTTVFAP--------NDDHSRRPLdrwLYVGYFVPVKGVDRLInlySQWR--AANGRSFgELVLAG 240
Cdd:cd03821   172 L--EPPIAVIPNGVDIPEFDPglrdrrkhNGLEDRRII---LFLGRIHPKKGLDLLI---RAARklAEQGRDW-HLVIAG 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 241 MGPLEEEL-RGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPV-ISTRCGGPEEtma 318
Cdd:cd03821   243 PDDGAYPAfLQLQSSLGLGDRVTFTGPLYGEAKWALYASADLFVLPSYSENFGNVVAEALACGLPVvITDKCGLSEL--- 319

                         250
                  ....*....|....*.
gi 2784009791 319 vaVESGDALLLAPEAQ 334
Cdd:cd03821   320 --VEAGCGVVVDPNVS 333
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 142-330 1.20e-15

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 78.90  E-value: 1.20e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 142 RAAYRTLLEASDLLLCAGDSEARILRAV-FPSErtKIRAVGNPIDTTVFAPnDDHSRRPLDRWLY----------VGYFV 210
Cdd:cd03807   124 RKLCLLLSKFSPATVANSSAVAEFHQEQgYAKN--KIVVIYNGIDLFKLSP-DDASRARARRRLGlaedrrvigiVGRLH 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 211 PVKGVDRLINLYSQWRAANGRSfgELVLAGMGPLEEELRGIAASSPYADEIKFVGplQRVAVARAMREADVLVHLSQHET 290
Cdd:cd03807   201 PVKDHSDLLRAAALLVETHPDL--RLLLVGRGPERPNLERLLLELGLEDRVHLLG--ERSDVPALLPAMDIFVLSSRTEG 276

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2784009791 291 FGVTVVEAAITGLPVISTRCGGPEETM----AVAVESGDALLLA 330
Cdd:cd03807   277 FPNALLEAMACGLPVVATDVGGAAELVddgtGFLVPAGDPQALA 320
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 169-306 1.29e-15

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 78.86  E-value: 1.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 169 VFPSERTK-----------IRAVGNPIDTTVFAPNDDHS---RRPLD----RWLYVGYFVPVKGVDRLINLYSQWRAANG 230
Cdd:cd03817   152 IAPSEKIKdtlreygvkgpIEVIPNGIDLDKFEKPLNTEerrKLGLPpdepILLYVGRLAKEKNIDFLLRAFAELKKEPN 231

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2784009791 231 rsfGELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVI 306
Cdd:cd03817   232 ---IKLVIVGDGPEREELKELARELGLADKVIFTGFVPREELPEYYKAADLFVFASTTETQGLVYLEAMAAGLPVV 304
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
204-332 3.33e-15

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 72.54  E-value: 3.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 204 LYVGYFVP-VKGVDRLINLYSQWRAANGRSfgELVLAGMGPlEEELRgiAASSPYADEIKFVGPLQrvAVARAMREADVL 282
Cdd:pfam13692   5 LFVGRLHPnVKGVDYLLEAVPLLRKRDNDV--RLVIVGDGP-EEELE--ELAAGLEDRVIFTGFVE--DLAELLAAADVF 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2784009791 283 VHLSQHETFGVTVVEAAITGLPVISTRCGGPEEtmavAVESGDALLLAPE 332
Cdd:pfam13692  78 VLPSLYEGFGLKLLEAMAAGLPVVATDVGGIPE----LVDGENGLLVPPG 123
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 202-316 3.74e-15

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 75.13  E-value: 3.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 202 RWLYVGYFVPVKGVDRLINLYSqwRAANGRSFGELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAM-READ 280
Cdd:cd01635   112 DKVSVGRLVPEKGIDLLLEALA--LLKARLPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGLVDDEVLELLlAAAD 189

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2784009791 281 VLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEET 316
Cdd:cd01635   190 VFVLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEF 225
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 143-340 3.89e-15

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 77.33  E-value: 3.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 143 AAYRTLLEASDLLLCAGDSEARILRAVfPSERTKIRAVGnpIDTTVFAPnddhSRR---PLDRW--------LYVGYFVP 211
Cdd:cd03814   137 AYLRWFHNPFDTTLVPSPSIARELEGH-GFERVRLWPRG--VDTELFHP----SRRdaaLRRRLgppgrpllLYVGRLAP 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 212 VKGVDRLINLysqWRAANGRSFGELVLAGMGPLEEELRgiaASSPyadEIKFVGPLQRVAVARAMREADVLVHLSQHETF 291
Cdd:cd03814   210 EKNLEALLDA---DLPLAASPPVRLVVVGDGPARAELE---ARGP---DVIFTGFLTGEELARAYASADVFVFPSRTETF 280

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2784009791 292 GVTVVEAAITGLPVISTRCGGPEE-----TMAVAVESGDALLLAPEAQHGDIDR 340
Cdd:cd03814   281 GLVVLEAMASGLPVVAADAGGPRDivrpgGTGALVEPGDAAAFAAALRALLEDP 334
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 120-315 1.59e-14

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 75.35  E-value: 1.59e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 120 GARLISIEHATFMRKKIRDDEGRAAYRTLLEASDL-LLCAGDSEARilravFPSERTKIRAVGNPIDTTVFAPNDDHSRR 198
Cdd:cd03820   108 KSKLIVWEHNNYEAYNKGLRRLLLRRLLYKRADKIvVLTEADKLKK-----YKQPNSNVVVIPNPLSFPSEEPSTNLKSK 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 199 pldRWLYVGYFVPVKGVDRLINLYSQ-------WraangrsfgELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQrvA 271
Cdd:cd03820   183 ---RILAVGRLTYQKGFDLLIEAWALiakkhpdW---------KLRIYGDGPEREELEKLIDKLGLEDRVKLLGPTK--N 248

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2784009791 272 VARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRC-GGPEE 315
Cdd:cd03820   249 IAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCpTGPSE 293
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 20-306 1.24e-12

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 69.70  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  20 GAFVAEWTRSLG-LPPNEVLIVHlrsvplgsPTSPVTREHELARVLEIPVAVSPEWHRARIARLHAEA---LAKHAPDEY 95
Cdd:cd03809    17 GRYTRELLKALAkNDPDESVLAV--------PPLPGELLRLLREYPELSLGVIKIKLWRELALLRWLQillPKKDKPDLL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  96 WHakvvhahvglPTGYAVAqnKPRGAR-------LISIEHATFMRKKIRDDEgRAAYRTLLEASDLLLCagDSEA---RI 165
Cdd:cd03809    89 HS----------PHNTAPL--LLKGCPqvvtihdLIPLRYPEFFPKRFRLYY-RLLLPISLRRADAIIT--VSEAtrdDI 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 166 LRaVFPSERTKIRAVGNPIDTTVFAPNDDHSRRPLDR-----WLYVGYFVPVKGVDRLINLYSQWRAANGRsfGELVLAG 240
Cdd:cd03809   154 IK-FYGVPPEKIVVIPLGVDPSFFPPESAAVLIAKYLlpepyFLYVGTLEPRKNHERLLKAFALLKKQGGD--LKLVIVG 230

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2784009791 241 -MGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVI 306
Cdd:cd03809   231 gKGWEDEELLDLVKKLGLGGRVRFLGYVSDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVI 297
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 62-336 6.15e-12

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 67.38  E-value: 6.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  62 RVLEIPVAVSPeWHRARIARLHAEalakhapdeyWHAKVVHAHVGLPTGYAVAQNKPRGARLISIEHATFMRKKIrddeG 141
Cdd:cd03819    52 PGLKVPLLRAL-LGNVRLARLIRR----------ERIDLIHAHSRAPAWLGWLASRLTGVPLVTTVHGSYLATYH----P 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 142 RAAYRTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDTTVFAPndDHSRRPLDRW---------LYVGYFVPV 212
Cdd:cd03819   117 KDFALAVRARGDRVIAVSELVRDHLIEALGVDPERIRVIPNGVDTDRFPP--EAEAEERAQLglpegkpvvGYVGRLSPE 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 213 KGVDRLINLYSQWRAAngRSFgELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAvaRAMREADVLVHLSQHETFG 292
Cdd:cd03819   195 KGWLLLVDAAAELKDE--PDF-RLLVAGDGPERDEIRRLVERLGLRDRVTFTGFREDVP--AALAASDVVVLPSLHEEFG 269

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2784009791 293 VTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHG 336
Cdd:cd03819   270 RVALEAMACGTPVVATDVGGAREI----VVHGRTGLLVPPGDAE 309
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 100-339 9.32e-12

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 66.99  E-value: 9.32e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 100 VVHAHVGLP---TGYAVAQNKPRGARLISIEHATFMRKKIRDDEGRAAYRTLLEASDLLLCAGDSEARILRAVFPSERtK 176
Cdd:cd04962    87 VLHAHYAIPhasCAYLAREILGEKIPIVTTLHGTDITLVGYDPSLQPAVRFSINKSDRVTAVSSSLRQETYELFDVDK-D 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 177 IRAVGNPIDTTVFAPNDD---HSRR---PLDRWL-YVGYFVPVKGVDRLINLYSQWRaanGRSFGELVLAGMGPLEEELR 249
Cdd:cd04962   166 IEVIHNFIDEDVFKRKPAgalKRRLlapPDEKVViHVSNFRPVKRIDDVVRVFARVR---RKIPAKLLLVGDGPERVPAE 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 250 GIAASSPYADEIKFVGPLQRVAvaRAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGG-PEetmaVAVESGDALL 328
Cdd:cd04962   243 ELARELGVEDRVLFLGKQDDVE--ELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGiPE----VVKHGETGFL 316

                         250
                  ....*....|.
gi 2784009791 329 lapeAQHGDID 339
Cdd:cd04962   317 ----SDVGDVD 323
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 97-359 2.10e-11

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 65.55  E-value: 2.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  97 HAKVVHAHVGlPTGYAVAQNKPRG---ARLISIEHATFMRKKIRDdEGRAAYRTLLEASDLLL----CAGDseaRILRAV 169
Cdd:cd03799    70 AYDIIHCQFG-PLGALGALLRRLKvlkGKLVTSFRGYDISMYVIL-EGNKVYPQLFAQGDLFLpnceLFKH---RLIALG 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 170 FPSErtKIRAVGNPIDTTVF--APNDDHSRRPLdRWLYVGYFVPVKGVDRLINLYSqwRAANGRSFGELVLAGMGPLEEE 247
Cdd:cd03799   145 CDEK--KIIVHRSGIDCNKFrfKPRYLPLDGKI-RILTVGRLTEKKGLEYAIEAVA--KLAQKYPNIEYQIIGDGDLKEQ 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 248 LRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLS------QHETFGVTVVEAAITGLPVISTRCGG-PEetmavA 320
Cdd:cd03799   220 LQQLIQELNIGDCVKLLGWKPQEEIIEILDEADIFIAPSvtaadgDQDGPPNTLKEAMAMGLPVISTEHGGiPE-----L 294

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2784009791 321 VESGDALLLAPEAQHGDIDRILDFERNLPESMDSMVLNG 359
Cdd:cd03799   295 VEDGVSGFLVPERDAEAIAEKLTYLIEHPAIWPEMGKAG 333
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 191-315 9.61e-11

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 63.89  E-value: 9.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 191 PNDDHSRRPLdRWLYVGYFVPVKGVDRLINLYSQWRAANGrsfgELVLAGMGPLEEElrgiaASSPYADEIKFVGPLQRV 270
Cdd:cd03823   183 PRRRPGTERL-RFGYIGRLTEEKGIDLLVEAFKRLPREDI----ELVIAGHGPLSDE-----RQIEGGRRIAFLGRVPTD 252

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2784009791 271 AVARAMREADVLVHLSQ-HETFGVTVVEAAITGLPVISTRCGGPEE 315
Cdd:cd03823   253 DIKDFYEKIDVLVVPSIwPEPFGLVVREAIAAGLPVIASDLGGIAE 298
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 111-316 1.61e-10

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 63.07  E-value: 1.61e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 111 YAVAQNKPRGARLISiehATFMRKKIRDDEGRAAYRTlleasDLLLCAGDSEARILRAVFPSERTKIRAvgnPIDTTVFA 190
Cdd:cd03804   125 YLAESGLGKGIKSLL---ASLFLHYLRLWDVRTAQRV-----DLFIANSQFVARRIKKFYGRESTVIYP---PVDTDAFA 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 191 PNDDHsrrpLDRWLYVGYFVPVKGVDRLINLYSQwraaNGRsfgELVLAGMGPLEEELRGIAASSpyadeIKFVGPLQRV 270
Cdd:cd03804   194 PAADK----EDYYLTASRLVPYKRIDLAVEAFNE----LPK---RLVVIGDGPDLDRLRAMASPN-----VEFLGYQPDE 257

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2784009791 271 AVARAMREADVLVhLSQHETFGVTVVEAAITGLPVISTRCGGPEET 316
Cdd:cd03804   258 VLKELLSKARAFV-FAAEEDFGIVPVEAQACGTPVIAFGKGGALET 302
GT4_PIG-A-like cd03796
phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This ...
 162-314 1.21e-09

phosphatidylinositol N-acetylglucosaminyltransferase subunit A and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Phosphatidylinositol glycan-class A (PIG-A), an X-linked gene in humans, is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in glycosyl phosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is an important cellular structure that facilitates the attachment of many proteins to cell surfaces. Somatic mutations in PIG-A have been associated with Paroxysmal Nocturnal Hemoglobinuria (PNH), an acquired hematological disorder.


Pssm-ID: 340827 [Multi-domain]  Cd Length: 398  Bit Score: 60.71  E-value: 1.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 162 EARILRAVFPSERtkIRAVGNPIDTTVFAPNDDHSRRPLDRWLYVGYFVPVKGVDRLI-------NLYSQWRaangrsfg 234
Cdd:cd03796   157 ENTVLRASLDPRI--VSVIPNAVDSSDFTPDPSKPDPNKITIVVISRLVYRKGIDLLVgiipricKKHPNVR-------- 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 235 eLVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGG-P 313
Cdd:cd03796   227 -FIIGGDGPKRIELEEMREKYQLQDRVELLGAVPHEEVRDVLVQGHIFLNTSLTEAFCIAIVEAASCGLLVVSTRVGGiP 305


                  .
gi 2784009791 314 E 314
Cdd:cd03796   306 E 306
GT4_CapH-like cd03812
capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This ...
 100-315 2.08e-09

capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).


Pssm-ID: 340840 [Multi-domain]  Cd Length: 357  Bit Score: 59.61  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 100 VVHAHVGLPTG--YAVAqnKPRGAR-LISIEHATFMRKKIRDDEGRAAYRTLLEA-SDLLLCAGDSEARILRAVFPSERT 175
Cdd:cd03812    83 IVHVHGSSSNGiiLLLA--AKAGVPvRIAHSHNTKDSSIKLRKIRKNVLKKLIERlSTKYLACSEDAGEWLFGEVENGKF 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 176 KIraVGNPIDTTVFAPNDDHSRRPLDRWL--------YVGYFVPVKGVDRLINLYSQWRAANGRSfgELVLAGMGPLEEE 247
Cdd:cd03812   161 KV--IPNGIDIEKYKFNKEKRRKRRKLLIledklvlgHVGRFNEQKNHSFLIDIFEELKKKNPNV--KLVLVGEGELKEK 236

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2784009791 248 LRGIAASSPYADEIKFVGplQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEE 315
Cdd:cd03812   237 IKEKVKELGLEDKVIFLG--FRNDVSEILSAMDVFLFPSLYEGLPLVAVEAQASGLPCLLSDTITKEC 302
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 204-352 5.90e-09

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 58.05  E-value: 5.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 204 LYVGYFVPVKGVDRLInlysqwRAANGRSFgELVLAGMGPLEEELRGIAASSpYADEIKFVGPLQRVAVARAMREADVLV 283
Cdd:cd03795   195 LFIGRLVYYKGLDYLI------EAAQYLNY-PIVIGGEGPLKPDLEAQIELN-LLDNVKFLGRVDDEEKVIYLHLCDVFV 266

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2784009791 284 hLSQH---ETFGVTVVEAAITGLPVISTRCGGP-------EETmAVAVESGDALLLApEAqhgdIDRILDFErNLPESM 352
Cdd:cd03795   267 -FPSVlrsEAFGIVLLEAMMCGKPVISTNIGTGvpyvnnnGET-GLVVPPKDPDALA-EA----IDKLLSDE-ELRESY 337
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 275-359 4.30e-08

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 51.91  E-value: 4.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 275 AMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGDALLLAPEAQHGDI-DRILDFERNlPESMD 353
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEV----IEDGETGLLVPPGDPEALaEAILRLLED-PELRR 91


                  ....*.
gi 2784009791 354 SMVLNG 359
Cdd:COG0438    92 RLGEAA 97
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 208-355 9.32e-08

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 54.77  E-value: 9.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 208 YFVPVKGVDRLINLYSQWRAANGRSFGELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMRE--ADVLVHL 285
Cdd:cd04946   232 SIVPVKRIDLIIETLNSLCVAHPSICISWTHIGGGPLKERLEKLAENKLENVKVNFTGEVSNKEVKQLYKEndVDVFVNV 311

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2784009791 286 SQHETFGVTVVEAAITGLPVISTRCGGPEETmavaVESGD-ALLLAPEAQHGDI-DRILDFERNlPESMDSM 355
Cdd:cd04946   312 SESEGIPVSIMEAISFGIPVIATNVGGTREI----VENETnGLLLDKDPTPNEIvSSIMKFYLD-GGDYKTM 378
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 122-347 3.94e-07

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 52.45  E-value: 3.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 122 RLISIEHAtfmrkkiRDDEGRAAYRtLLEASDLLLCAGDSEAR------ILRAVFPseRTKIRAVGNPIDTTVFAPNDDH 195
Cdd:cd04951   105 LLICTAHN-------KNEGGRIRMF-IYRLTDFLCDITTNVSRealdefIAKKAFS--KNKSVPVYNGIDLNKFKKDINV 174

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 196 SRRPLDRW---------LYVGYFVPVKGVDRLINLYSQWRAANGRSfgELVLAGMGPLEEELRGIAASSPYADEIKFVGp 266
Cdd:cd04951   175 RLKIRNKLnlkndefviLNVGRLTEAKDYPNLLLAISELILSKNDF--KLLIAGDGPLRNELERLICNLNLVDRVILLG- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 267 lQRVAVARAMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEET---MAVAVESGDALLLAPEaqhgdIDRILD 343
Cdd:cd04951   252 -QISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVvgdHNYVVPVSDPQLLAEK-----IKEIFD 325


                  ....
gi 2784009791 344 FERN 347
Cdd:cd04951   326 MSDE 329
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 163-332 4.21e-07

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 52.33  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 163 ARILRAVFPSERTKIRAVGNPIDTTVFAPNDDHSRRPLDRwlyvgyfvpVKGVDRLINLYSQWRAANGRSFGELVlagmg 242
Cdd:cd03825   149 ADMVRRSPLLKGLPVVVIPNGIDTEIFAPVDKAKARKRLG---------IPQDKKVILFGAESVTKPRKGFDELI----- 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 243 pleEELRGIAASSPYadEIKFVG--PLQRVAVARAMRE----------------ADVLVHLSQHETFGVTVVEAAITGLP 304
Cdd:cd03825   215 ---EALKLLATKDDL--LLVVFGknDPQIVILPFDIISlgyidddeqlvdiysaADLFVHPSLADNLPNTLLEAMACGTP 289

                         170       180
                  ....*....|....*....|....*...
gi 2784009791 305 VISTRCGGPEEtmavAVESGDALLLAPE 332
Cdd:cd03825   290 VVAFDTGGSPE----IVQHGVTGYLVPP 313
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 180-316 1.96e-06

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 49.98  E-value: 1.96e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 180 VGNPIDTTVFAPNDDHsRRPLdrwLYVGYFVPVKGVDRLInlysqwRAAngRSFG-ELVLAGMGPLEEELRGIAASSPYA 258
Cdd:cd03802   153 VHNGLDPADYRFQPDP-EDYL---AFLGRIAPEKGLEDAI------RVA--RRAGlPLKIAGKVRDEDYFYYLQEPLPGP 220

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2784009791 259 DeIKFVGPLQRVAVARAMREADVLVHLSQ-HETFGVTVVEAAITGLPVISTRCGGPEET 316
Cdd:cd03802   221 R-IEFIGEVGHDEKQELLGGARALLFPINwDEPFGLVMIEAMACGTPVIAYRRGGLPEV 278
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
49-186 1.05e-05

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 45.99  E-value: 1.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  49 SPTSPVTREHELARVLEIPVAVSP----EWHRARIARLHAEALAKHAPDeywhakVVHAHVGLPTGYAV-AQNKPRGARL 123
Cdd:pfam13439  25 TPGGPGPLAEEVVRVVRVPRVPLPlpprLLRSLAFLRRLRRLLRRERPD------VVHAHSPFPLGLAAlAARLRLGIPL 98

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 124 ISIEHATF-------MRKKIRDDEGRAAYRTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDT 186
Cdd:pfam13439  99 VVTYHGLFpdykrlgARLSPLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKIRVIPNGVDL 168
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 146-339 1.14e-05

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 48.17  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 146 RTLLEASDLLLCAGDSEARILRAVFPSERTKIRAVGNPIDTTVFAP-----------NDDHSRRPLdrWLYVGYFVPVKG 214
Cdd:PLN02871  200 RFLHRAADLTLVTSPALGKELEAAGVTAANRIRVWNKGVDSESFHPrfrseemrarlSGGEPEKPL--IVYVGRLGAEKN 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 215 VDRLINLYSQWRAANgrsfgeLVLAGMGPLEEELRGIAASSPyadeIKFVGPLQRVAVARAMREADVLVHLSQHETFGVT 294
Cdd:PLN02871  278 LDFLKRVMERLPGAR------LAFVGDGPYREELEKMFAGTP----TVFTGMLQGDELSQAYASGDVFVMPSESETLGFV 347

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2784009791 295 VVEAAITGLPVISTRCGGPEETMAVAVESGDALLLAPeaqhGDID 339
Cdd:PLN02871  348 VLEAMASGVPVVAARAGGIPDIIPPDQEGKTGFLYTP----GDVD 388
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 276-359 1.18e-05

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 47.70  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 276 MREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGpeetMAVAVESGDALLLAPEAQhGDIDRILDFERNlPESMDSM 355
Cdd:cd03792   277 QRAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGG----IPLQVIDGETGFLVNSVE-GAAVRILRLLTD-PELRRKM 350


                  ....
gi 2784009791 356 VLNG 359
Cdd:cd03792   351 GLAA 354
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 98-312 2.26e-05

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 47.33  E-value: 2.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791  98 AKVVHAHvglPTGYA----VAQNKPRGARLISIEHATFMRKK----IRDDEGRAAYRTLL------------EASDLLLc 157
Cdd:cd03813   174 ADLYHSV---STGYAgllgALARHRRGIPFLLTEHGIYTRERkieiLQSTWIMGYIKKLWirfferlgklayQQADKII- 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 158 AGDSEARILRAVFPSERTKIRAVGNPIDTTVFAP-NDDHSRRPLDRWLYVGYFVPVKGVDRLInlysqwraangRSFGEL 236
Cdd:cd03813   250 SLYEGNRRRQIRLGADPDKTRVIPNGIDIQRFAPaREERPEKEPPVVGLVGRVVPIKDVKTFI-----------RAFKLV 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 237 VLAG-------MGPLEE------ELRGIAASSPYADEIKFVGplqRVAVARAMREADVLVHLSQHETFGVTVVEAAITGL 303
Cdd:cd03813   319 RRAMpdaegwlIGPEDEdpeyaqECKRLVASLGLENKVKFLG---FQNIKEYYPKLGLLVLTSISEGQPLVILEAMASGV 395


                  ....*....
gi 2784009791 304 PVISTRCGG 312
Cdd:cd03813   396 PVVATDVGS 404
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 226-342 2.27e-04

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 44.25  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 226 RAANGRSFGELVLAGMGPLEEELRGIAASSPYADEIKFVGPLQRVAVARAMREADVLvhLSQHETFGVTVVEAAITGLPV 305
Cdd:PRK15179  541 RFAASHPKVRFIMVGGGPLLESVREFAQRLGMGERILFTGLSRRVGYWLTQFNAFLL--LSRFEGLPNVLIEAQFSGVPV 618

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2784009791 306 ISTRCGGPEETMAVAVESgdALLLAPEAQHGDIDRIL 342
Cdd:PRK15179  619 VTTLAGGAGEAVQEGVTG--LTLPADTVTAPDVAEAL 653
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 142-316 6.62e-04

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 42.19  E-value: 6.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 142 RAAYRT---LLE-----ASDLLLCAGDSEARILRAVFPSERTKIRAVGNP-IDTTVF-APNDDHSRRPLDRWLYVGYFVP 211
Cdd:cd03805   137 KRLYRKpfdWLEefttgMADQIVVNSNFTAGVFKKTFPSLAKNPPEVLYPcVDTDSFdSTSEDPDPGDLIAKSNKKFFLS 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2784009791 212 V------KGVDRLINLYSQWRAaNGRSFGE--LVLAG--MGPLEE------ELRGIAAS-SPYADEIKF---VGPLQRVA 271
Cdd:cd03805   217 InrferkKNIALAIEAFAKLKQ-KLPEFENvrLVIAGgyDPRVAEnveyleELQRLAEElLNVEDQVLFlrsISDSQKEQ 295

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2784009791 272 VaraMREADVLVHLSQHETFGVTVVEAAITGLPVISTRCGGPEET 316
Cdd:cd03805   296 L---LSSALALLYTPSNEHFGIVPLEAMYAGKPVIACNSGGPLET 337
sucrsPsyn_pln TIGR02468
sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this ...
 289-313 2.08e-03

sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Members of this family are sucrose-phosphate synthases of plants. This enzyme is known to exist in multigene families in several species of both monocots and dicots. The N-terminal domain is the glucosyltransferase domain. Members of this family also have a variable linker region and a C-terminal domain that resembles sucrose phosphate phosphatase (SPP) (EC 3.1.3.24) (see TIGR01485), the next and final enzyme of sucrose biosynthesis. The SPP-like domain likely serves a binding and not a catalytic function, as the reported SPP is always encoded by a distinct protein.


Pssm-ID: 274147 [Multi-domain]  Cd Length: 1050  Bit Score: 41.30  E-value: 2.08e-03
                           10        20
                   ....*....|....*....|....*
gi 2784009791  289 ETFGVTVVEAAITGLPVISTRCGGP 313
Cdd:TIGR02468  582 EPFGLTLIEAAAHGLPMVATKNGGP 606
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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