matrixin family metalloprotease [Thomasclavelia spiroformis]
Protein Classification
zinc metalloprotease( domain architecture ID 1881)
zinc metalloprotease may be a member of the astacin-like protease family or the adamalysin/reprolysin-like protease family
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| ZnMc super family | cl00064 | Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major ... |
22-68 | 3.67e-07 | ||
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which are involved in vertebrate development and disease. The actual alignment was detected with superfamily member cd04278: Pssm-ID: 469599 [Multi-domain] Cd Length: 157 Bit Score: 44.12 E-value: 3.67e-07
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| Name | Accession | Description | Interval | E-value | ||
| ZnMc_MMP | cd04278 | Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are ... |
22-68 | 3.67e-07 | ||
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate specification, cell migration, tissue repair, tumorigenesis, gain or loss of tissue-specific functions, and apoptosis. In many instances, they are anchored to cell membranes via trans-membrane domains, and their activity is controlled via TIMPs (tissue inhibitors of metalloproteinases). Pssm-ID: 239805 [Multi-domain] Cd Length: 157 Bit Score: 44.12 E-value: 3.67e-07
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| Peptidase_M10 | pfam00413 | Matrixin; The members of this family are enzymes that cleave peptides. These proteases require ... |
17-68 | 2.38e-06 | ||
Matrixin; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Pssm-ID: 425668 [Multi-domain] Cd Length: 159 Bit Score: 42.22 E-value: 2.38e-06
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| COG5549 | COG5549 | Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; ... |
12-68 | 2.79e-03 | ||
Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 444292 [Multi-domain] Cd Length: 234 Bit Score: 33.89 E-value: 2.79e-03
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| Name | Accession | Description | Interval | E-value | ||
| ZnMc_MMP | cd04278 | Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are ... |
22-68 | 3.67e-07 | ||
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate specification, cell migration, tissue repair, tumorigenesis, gain or loss of tissue-specific functions, and apoptosis. In many instances, they are anchored to cell membranes via trans-membrane domains, and their activity is controlled via TIMPs (tissue inhibitors of metalloproteinases). Pssm-ID: 239805 [Multi-domain] Cd Length: 157 Bit Score: 44.12 E-value: 3.67e-07
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| Peptidase_M10 | pfam00413 | Matrixin; The members of this family are enzymes that cleave peptides. These proteases require ... |
17-68 | 2.38e-06 | ||
Matrixin; The members of this family are enzymes that cleave peptides. These proteases require zinc for catalysis. Pssm-ID: 425668 [Multi-domain] Cd Length: 159 Bit Score: 42.22 E-value: 2.38e-06
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| COG5549 | COG5549 | Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; ... |
12-68 | 2.79e-03 | ||
Predicted Zn-dependent protease [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 444292 [Multi-domain] Cd Length: 234 Bit Score: 33.89 E-value: 2.79e-03
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| Blast search parameters | ||||
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