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Conserved domains on  [gi|2786060716|ref|WP_369769853|]
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carbohydrate kinase family protein [Glaciecola sp. HTCC2999]

Protein Classification

carbohydrate kinase family protein( domain architecture ID 10001647)

carbohydrate kinase family protein similar to Thermococcus kodakarensis cytidine kinase, which phosphorylates cytidine in nucleoside degradation pathways

CATH:  3.40.1190.20
EC:  2.7.1.-
Gene Ontology:  GO:0016310|GO:0016773|GO:0005829|GO:0016301|GO:0005975|GO:0005524|GO:0019200
PubMed:  8382990|12095261
SCOP:  3001268|4000759

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 2-101 2.99e-24

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 93.03  E-value: 2.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   2 EMLYGIDNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESV 81
Cdd:COG0524   197 ELLTGETDPEEAAAALLARGVKLVVVTLGAEGALLYTGGEVVHVPAFPVE-VVDTTGAGDAFAAGFLAGLLEGLDLEEAL 275

                          90       100
                  ....*....|....*....|
gi 2786060716  82 RAGAAMAGIVIQHPGAIIPL 101
Cdd:COG0524   276 RFANAAAALVVTRPGAQPAL 295
 
Name Accession Description Interval E-value
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 2-101 2.99e-24

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 93.03  E-value: 2.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   2 EMLYGIDNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESV 81
Cdd:COG0524   197 ELLTGETDPEEAAAALLARGVKLVVVTLGAEGALLYTGGEVVHVPAFPVE-VVDTTGAGDAFAAGFLAGLLEGLDLEEAL 275

                          90       100
                  ....*....|....*....|
gi 2786060716  82 RAGAAMAGIVIQHPGAIIPL 101
Cdd:COG0524   276 RFANAAAALVVTRPGAQPAL 295
KdgK cd01166
2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form ...
 1-98 5.73e-24

2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.


Pssm-ID: 238571 [Multi-domain]  Cd Length: 294  Bit Score: 92.25  E-value: 5.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   1 MEMLYGIDNADDTVAFF--DEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIE 78
Cdd:cd01166   196 AEALLGDEDPTDAAERAlaLALGVKAVVVKLGAEGALVYTGGGRVFVPAYPVE-VVDTTGAGDAFAAGFLAGLLEGWDLE 274

                          90       100
                  ....*....|....*....|
gi 2786060716  79 ESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01166   275 EALRFANAAAALVVTRPGDI 294
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 22-99 4.61e-19

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 79.31  E-value: 4.61e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2786060716  22 IEELIIKDGANTVQVIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAII 99
Cdd:pfam00294 217 IKTVIVTLGADGALVVEGDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAGLLAGKSLEEALRFANAAAALVVQKSGAQT 294
PTZ00247 PTZ00247
adenosine kinase; Provisional
 27-100 2.47e-13

adenosine kinase; Provisional


Pssm-ID: 240328 [Multi-domain]  Cd Length: 345  Bit Score: 63.89  E-value: 2.47e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2786060716  27 IKDGANTVQVIhsgktyliPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAIIP 100
Cdd:PTZ00247  273 TKDGVTSVPVP--------PLDQEK-IVDTNGAGDAFVGGFLAQYANGKDIDRCVEAGHYSAQVIIQHNGCTYP 337
D_ribokin_bact TIGR02152
ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose ...
 2-97 3.32e-13

ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars]


Pssm-ID: 274000 [Multi-domain]  Cd Length: 293  Bit Score: 63.39  E-value: 3.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   2 EMLYGI-----DNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQP 76
Cdd:TIGR02152 183 EILTGIevtdeEDAEKAAEKLLEKGVKNVIITLGSKGALLVSKDESKLIPAFKVK-AVDTTAAGDTFNGAFAVALAEGKS 261

                          90       100
                  ....*....|....*....|.
gi 2786060716  77 IEESVRAGAAMAGIVIQHPGA 97
Cdd:TIGR02152 262 LEDAIRFANAAAAISVTRKGA 282
 
Name Accession Description Interval E-value
RbsK COG0524
Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar ...
 2-101 2.99e-24

Sugar or nucleoside kinase, ribokinase family [Carbohydrate transport and metabolism]; Sugar or nucleoside kinase, ribokinase family is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 440290 [Multi-domain]  Cd Length: 301  Bit Score: 93.03  E-value: 2.99e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   2 EMLYGIDNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESV 81
Cdd:COG0524   197 ELLTGETDPEEAAAALLARGVKLVVVTLGAEGALLYTGGEVVHVPAFPVE-VVDTTGAGDAFAAGFLAGLLEGLDLEEAL 275

                          90       100
                  ....*....|....*....|
gi 2786060716  82 RAGAAMAGIVIQHPGAIIPL 101
Cdd:COG0524   276 RFANAAAALVVTRPGAQPAL 295
KdgK cd01166
2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form ...
 1-98 5.73e-24

2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.


Pssm-ID: 238571 [Multi-domain]  Cd Length: 294  Bit Score: 92.25  E-value: 5.73e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   1 MEMLYGIDNADDTVAFF--DEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIE 78
Cdd:cd01166   196 AEALLGDEDPTDAAERAlaLALGVKAVVVKLGAEGALVYTGGGRVFVPAYPVE-VVDTTGAGDAFAAGFLAGLLEGWDLE 274

                          90       100
                  ....*....|....*....|
gi 2786060716  79 ESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01166   275 EALRFANAAAALVVTRPGDI 294
PfkB pfam00294
pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine ...
 22-99 4.61e-19

pfkB family carbohydrate kinase; This family includes a variety of carbohydrate and pyrimidine kinases.


Pssm-ID: 425587 [Multi-domain]  Cd Length: 294  Bit Score: 79.31  E-value: 4.61e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2786060716  22 IEELIIKDGANTVQVIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAII 99
Cdd:pfam00294 217 IKTVIVTLGADGALVVEGDGEVHVPAVPKVKVVDTTGAGDSFVGGFLAGLLAGKSLEEALRFANAAAALVVQKSGAQT 294
ribokinase_group_A cd01942
Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ...
 22-98 1.03e-17

Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238917 [Multi-domain]  Cd Length: 279  Bit Score: 75.43  E-value: 1.03e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2786060716  22 IEELIIKDGANTVQVIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01942   203 VRVVVVTLGPKGAIVFEDGEEVEVPAVPAVKVVDTTGAGDAFRAGFLYGLLRGYDLEESLRLGNLAASLKVERRGAQ 279
adenosine_kinase cd01168
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside ...
 26-100 1.22e-17

Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine levels and the preservation of intracellular adenylate pools. Adenosine kinase is involved in the purine salvage pathway.


Pssm-ID: 238573 [Multi-domain]  Cd Length: 312  Bit Score: 75.73  E-value: 1.22e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2786060716  26 IIKDGANTVQVIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAIIP 100
Cdd:cd01168   238 VITQGAKGAVVVEGGEVYPVPAIPVEKIVDTNGAGDAFAGGFLYGLVQGEPLEECIRLGSYAAAEVIQQLGPRLP 312
ribokinase cd01174
Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This ...
 22-97 1.41e-13

Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.


Pssm-ID: 238579 [Multi-domain]  Cd Length: 292  Bit Score: 64.11  E-value: 1.41e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2786060716  22 IEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGA 97
Cdd:cd01174   212 VKNVIVTLGAKGALLASGGEVEHVPAFKVK-AVDTTGAGDTFIGALAAALARGLSLEEAIRFANAAAALSVTRPGA 286
PTZ00247 PTZ00247
adenosine kinase; Provisional
 27-100 2.47e-13

adenosine kinase; Provisional


Pssm-ID: 240328 [Multi-domain]  Cd Length: 345  Bit Score: 63.89  E-value: 2.47e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2786060716  27 IKDGANTVQVIhsgktyliPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAIIP 100
Cdd:PTZ00247  273 TKDGVTSVPVP--------PLDQEK-IVDTNGAGDAFVGGFLAQYANGKDIDRCVEAGHYSAQVIIQHNGCTYP 337
D_ribokin_bact TIGR02152
ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose ...
 2-97 3.32e-13

ribokinase; This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars]


Pssm-ID: 274000 [Multi-domain]  Cd Length: 293  Bit Score: 63.39  E-value: 3.32e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   2 EMLYGI-----DNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQP 76
Cdd:TIGR02152 183 EILTGIevtdeEDAEKAAEKLLEKGVKNVIITLGSKGALLVSKDESKLIPAFKVK-AVDTTAAGDTFNGAFAVALAEGKS 261

                          90       100
                  ....*....|....*....|.
gi 2786060716  77 IEESVRAGAAMAGIVIQHPGA 97
Cdd:TIGR02152 262 LEDAIRFANAAAAISVTRKGA 282
bac_FRK cd01167
Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for ...
 1-98 1.62e-12

Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.


Pssm-ID: 238572 [Multi-domain]  Cd Length: 295  Bit Score: 61.50  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   1 MEMLYGIDNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYL------GARMNG 74
Cdd:cd01167   192 LELLFGEEDPEEIAALLLLFGLKLVLVTRGADGALLYTKGGVGEVPGIPVE-VVDTTGAGDAFVAGLLaqllsrGLLALD 270

                          90       100
                  ....*....|....*....|....*
gi 2786060716  75 Q-PIEESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01167   271 EdELAEALRFANAVGALTCTKAGAI 295
PLN02548 PLN02548
adenosine kinase
 26-100 2.58e-12

adenosine kinase


Pssm-ID: 178163 [Multi-domain]  Cd Length: 332  Bit Score: 60.88  E-value: 2.58e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2786060716  26 IIKDGANTVQVIHSGKTYLIPITPVK--HVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAIIP 100
Cdd:PLN02548  250 VITQGADPTVVAEDGKVKEFPVIPLPkeKLVDTNGAGDAFVGGFLSQLVQGKDIEECVRAGNYAANVIIQRSGCTYP 326
ribokinase_group_B cd01945
Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ...
 40-97 1.23e-10

Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .


Pssm-ID: 238920 [Multi-domain]  Cd Length: 284  Bit Score: 56.15  E-value: 1.23e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2786060716  40 GKTYLIPITPVkHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGA 97
Cdd:cd01945   222 GELFHVPAFPV-EVVDTTGAGDVFHGAFAHALAEGMPLREALRFASAAAALKCRGLGG 278
PRK11142 PRK11142
ribokinase; Provisional
 22-97 3.69e-10

ribokinase; Provisional


Pssm-ID: 236858 [Multi-domain]  Cd Length: 306  Bit Score: 54.88  E-value: 3.69e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2786060716  22 IEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGA 97
Cdd:PRK11142  215 IETVLITLGSRGVWLSENGEGQRVPGFRVQ-AVDTIAAGDTFNGALVTALLEGKPLPEAIRFAHAAAAIAVTRKGA 289
YegV_kinase_like cd01944
YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase ...
 25-96 2.17e-09

YegV-like sugar kinase. Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238919 [Multi-domain]  Cd Length: 289  Bit Score: 52.81  E-value: 2.17e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2786060716  25 LIIKDGANTVQVIHS-GKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPG 96
Cdd:cd01944   218 VVVRLGSNGAWIRLPdGNTHIIPGFKVK-AVDTIGAGDTHAGGMLAGLAKGMSLADAVLLANAAAAIVVTRSG 289
Guanosine_kinase_like cd01947
Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like ...
 25-98 4.80e-09

Guanosine kinase-like sugar kinases. Found in bacteria and archaea, the guanosine kinase-like group is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238922 [Multi-domain]  Cd Length: 265  Bit Score: 51.65  E-value: 4.80e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2786060716  25 LIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01947   193 LIVTEGELGAILYPGGRYNHVPAKKAK-VPDSTGAGDSFAAGFIYGLLKGWSIEEALELGAQCGAICVSHFGPY 265
PRK09813 PRK09813
fructoselysine 6-kinase; Provisional
 43-97 7.54e-08

fructoselysine 6-kinase; Provisional


Pssm-ID: 182090 [Multi-domain]  Cd Length: 260  Bit Score: 48.20  E-value: 7.54e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2786060716  43 YLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGA 97
Cdd:PRK09813  206 WRQAPEPVT-VVDTMGAGDSFIAGFLCGWLAGMTLPQAMAQGTACAAKTIQYHGA 259
ribokinase_group_D cd01937
Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ...
 16-92 8.41e-08

Ribokinase-like subgroup D. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238912 [Multi-domain]  Cd Length: 254  Bit Score: 48.17  E-value: 8.41e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2786060716  16 FFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVI 92
Cdd:cd01937   178 LIKETGVKEIIVTDGEEGGYIFDGNGKYTIPASKKD-VVDPTGAGDVFLAAFLYSRLSGKDIKEAAEFAAAAAAKFI 253
Fructoselysine_kinase_like cd01940
Fructoselysine kinase-like. Fructoselysine is a fructoseamine formed by glycation, a ...
 30-97 5.56e-07

Fructoselysine kinase-like. Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the lysine side chains. Fructoseamines are typically metabolized by fructoseamine-3-kinase, especially in higher eukaryotes. In E. coli, fructoselysine kinase has been shown in vitro to catalyze the phosphorylation of fructoselysine. It is proposed that fructoselysine is released from glycated proteins during human digestion and is partly metabolized by bacteria in the hind gut using a protein such as fructoselysine kinase. This family is found only in bacterial sequences, and its oligomeric state is currently unknown.


Pssm-ID: 238915 [Multi-domain]  Cd Length: 264  Bit Score: 45.81  E-value: 5.56e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2786060716  30 GANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQ-PIEESVRAGAAMAGIVIQHPGA 97
Cdd:cd01940   196 GEDGAIAYDGAVFYSVAPRPVE-VVDTLGAGDSFIAGFLLSLLAGGtAIAEAMRQGAQFAAKTCGHEGA 263
YeiC_kinase_like cd01941
YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ...
 22-94 8.67e-07

YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238916 [Multi-domain]  Cd Length: 288  Bit Score: 45.38  E-value: 8.67e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2786060716  22 IEELIIKDGANTVQVIHSG----KTYLIPITPVKhVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQH 94
Cdd:cd01941   213 IKNVIVTLGAKGVLLSSREggveTKLFPAPQPET-VVNVTGAGDAFVAGLVAGLLEGMSLDDSLRFAQAAAALTLES 288
PRK09434 PRK09434
aminoimidazole riboside kinase; Provisional
 8-68 9.01e-07

aminoimidazole riboside kinase; Provisional


Pssm-ID: 236514 [Multi-domain]  Cd Length: 304  Bit Score: 45.31  E-value: 9.01e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2786060716   8 DNADDTVAFFDEFDIEELIIKDGANTVQVIHSGKTYLIPITPVKhVVDTTSAGDSFNGAYL 68
Cdd:PRK09434  199 QLEDAIYALADRYPIALLLVTLGAEGVLVHTRGQVQHFPAPSVD-PVDTTGAGDAFVAGLL 258
RfaE COG2870
ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane ...
 36-96 3.30e-06

ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442117 [Multi-domain]  Cd Length: 321  Bit Score: 43.65  E-value: 3.30e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2786060716  36 VIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPG 96
Cdd:COG2870   250 LFDADGPPHHLPAQAREVFDVTGAGDTVIATLALALAAGASLEEAAELANLAAGIVVGKLG 310
ribokinase_group_C cd01946
Ribokinase-like subgroup C. Found only in bacteria, this subgroup is part of the ribokinase ...
 25-93 1.26e-05

Ribokinase-like subgroup C. Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.


Pssm-ID: 238921 [Multi-domain]  Cd Length: 277  Bit Score: 42.07  E-value: 1.26e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2786060716  25 LIIKDGANTVQVIHSGKTYLIPITPVKHVVDTTSAGDSFNGAYLG--ARMNGQPIEESVRA---GAAMAGIVIQ 93
Cdd:cd01946   198 LIIKRGEYGALLFTDDGYFAAPAYPLESVFDPTGAGDTFAGGFIGylASQKDTSEANMRRAiiyGSAMASFCVE 271
PLN02379 PLN02379
pfkB-type carbohydrate kinase family protein
 26-96 1.36e-05

pfkB-type carbohydrate kinase family protein


Pssm-ID: 178005 [Multi-domain]  Cd Length: 367  Bit Score: 42.09  E-value: 1.36e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2786060716  26 IIKDGANTVQVIHSGKTylipitpvkHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPG 96
Cdd:PLN02379  279 IARHGKEVVRVPAIGET---------NAVDATGAGDLFASGFLYGLIKGLSLEECCKVGACSGGSVVRALG 340
PTZ00292 PTZ00292
ribokinase; Provisional
 3-97 1.38e-05

ribokinase; Provisional


Pssm-ID: 185541 [Multi-domain]  Cd Length: 326  Bit Score: 42.03  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716   3 MLYGIDNADDTVAF--FDEF---DIEELIIKDGANTvQVIHSGKTYLIPITPVK-HVVDTTSAGDSFNGAYLGARMNGQP 76
Cdd:PTZ00292  211 LITGMEVTDTESAFkaSKELqqlGVENVIITLGANG-CLIVEKENEPVHVPGKRvKAVDTTGAGDCFVGSMAYFMSRGKD 289

                          90       100
                  ....*....|....*....|.
gi 2786060716  77 IEESVRAGAAMAGIVIQHPGA 97
Cdd:PTZ00292  290 LKESCKRANRIAAISVTRHGT 310
RfaE_like cd01172
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the ...
 39-98 4.32e-03

RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer membrane of gram-negative bacteria. RfaE consists of two domains, a sugar kinase domain, represented here, and a domain belonging to the cytidylyltransferase superfamily.


Pssm-ID: 238577 [Multi-domain]  Cd Length: 304  Bit Score: 34.84  E-value: 4.32e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786060716  39 SGKTYLIPiTPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPGAI 98
Cdd:cd01172   237 DGEVQHIP-ALAKEVYDVTGAGDTVIATLALALAAGADLEEAAFLANAAAGVVVGKVGTA 295
MAK32 cd01943
MAK32 kinase. MAK32 is a protein found primarily in fungi that is necessary for the ...
 48-96 5.33e-03

MAK32 kinase. MAK32 is a protein found primarily in fungi that is necessary for the structural stability of L-A particles. The L-A virus particule is a specialized compartment for the transcription and replication of double-stranded RNA, known to infect yeast and other fungi. MAK32 is part of the host machinery used by the virus to multiply.


Pssm-ID: 238918 [Multi-domain]  Cd Length: 328  Bit Score: 34.62  E-value: 5.33e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2786060716  48 TPVKHVVDTTSAGDSFNGAYLGARMNGQPIEESVRAGAAMAGIVIQHPG 96
Cdd:cd01943   255 TKSTKVVDPTGGGNSFLGGFAAGLALTKSIDEACIYGSVAASFAIEQVG 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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