|
Name |
Accession |
Description |
Interval |
E-value |
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
3-575 |
0e+00 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 684.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 3 VLGGVIVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPEDVI 82
Cdd:TIGR03423 5 VLGGLVLALFGVLAARLFYLQVIRGEEYATLSEDNRIRLVPIPPPRGLILDRNGVLLADNRPSFSLEIVPEKVDDLDATL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 83 ERLSVLLHVPTEEI---HKKIDAHVGFDPIRIKQDIGPEVYTIIEEQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEI 159
Cdd:TIGR03423 85 DRLAKLLDLDPEDIarfLKELKRSRRFEPIPLKSDLTEEEVARFAVNQYRLPGVEIEARLKRYYPYGELAAHVLGYVGEI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 160 SNEELEKRKAEGYKSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGTKEPIAGNDLVLTIDATIQVAAERAI 239
Cdd:TIGR03423 165 NEEDLERLEPANYAGGDYIGKSGIEKYYEDELRGKPGYREVEVNARGRVIRTLSRVPPVPGKDLVLTIDARLQQAAEKAL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 240 DQQlsaiganAAAAVVMNPQTGEVLALVSRPSFDPNLFVNGISTKDWKVINENPYHPMDNKAITGEYPPGSTFKIVTGTA 319
Cdd:TIGR03423 245 GGR-------RGAVVVMDPRTGEILAMVSTPSFDPNLFVDGISSKDYKALLNDPDRPLLNRAIQGVYPPGSTFKPVVALA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 320 ALQENVVSPNEIIYDSGrHWIIPKG-----NAGGEalGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTG 394
Cdd:TIGR03423 318 ALEEGVITPETRIYCPG-YFQLGGRrfrcwKRGGH--GRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFGQKTG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 395 IDLPYEAEGLVPSREYKKKVYEDDWYLSETFDAAIGQGFDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETI 474
Cdd:TIGR03423 395 IDLPGEKSGLVPSREWKRKRFGQPWYPGDTLNVSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRT 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 475 KPKRIGRLDVRPEVIALVQQGLRDVTK--YGTAAAAFgAKYPVDIAGKTGTAE---------------NSHGRDHGWFVA 537
Cdd:TIGR03423 475 EPEVLRPLPISPENLDVVREGMRDVVNgpGGTARRAR-LGLPYKMAGKTGTAQvvslkqgekydaeqiPERLRDHALFVA 553
|
570 580 590
....*....|....*....|....*....|....*...
gi 2786099445 538 YGPFNNPTIVVAVIVEQGGFGSLSAVPIGKKILDAAFG 575
Cdd:TIGR03423 554 FAPYDNPKIAVAVIVEHGGGGSSAAAPIARKIMDAYLL 591
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
1-579 |
0e+00 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 588.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 1 MHVLGGVIVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPED 80
Cdd:COG0768 14 LLLLFLLVLLLFLLLVGRLFYLQVVEGDEYAELAEENRIRTVPIPAPRGLIYDRNGNVLATNVPVYSLYADPEEVKDPEE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 81 VIERLSVLLHVPTEEIHKKIDAHVGFdPIRIKQDIGPEVYTIIeeQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEIS 160
Cdd:COG0768 94 TAEKLAKLLGLDPEELRKKLKKKSRF-PVYLKRNLSPEEAARI--RALKLPGVYVEAEYKRYYPYGELAAHVLGYVGEIN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 161 neelekrkaegykSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLG-TKEPIAGNDLVLTIDATIQVAAERAI 239
Cdd:COG0768 171 -------------GGDGIGKSGLEKAYEDLLRGTPGKRRVEVDARGRVIRDLGeEKPPVPGKDLVLTIDSDLQKIAEEAL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 240 DQQLSAIGANAAAAVVMNPQTGEVLALVSRPSFDPNLFVNGistkdwkvinenPYHPMDNKAITGEYPPGSTFKIVTGTA 319
Cdd:COG0768 238 KKAVEEYKAKSGAVVVMDPKTGEILAMASYPSFDPNLFVGG------------PDEPLRNRAVQGTYEPGSTFKPFTAAA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 320 ALQENVVSPNEIIYDSGRHWIIPK--GNAGGEALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTGIDL 397
Cdd:COG0768 306 ALEEGVITPDTTFDCPGYYRVGGRtiRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTGIDL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 398 PYEAEGLVPSREykkkvyedDWYLSETFDAAIGQGFdLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETiKPK 477
Cdd:COG0768 386 PGEASGLLPSPK--------RWYPGETATMSIGQGL-SVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKE-EPE 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 478 RIGRLdVRPEVIALVQQGLRDVT--KYGTAAAAFGAKYPVdiAGKTGTAEN--------SHGRDHGWFVAYGPFNNPTIV 547
Cdd:COG0768 456 VLRRV-ISPETAETVREGMEGVVnePGGTARRAAIPGYRV--AGKTGTAQVvdignggyYKGRHIASFVGFAPADNPRYA 532
|
570 580 590
....*....|....*....|....*....|....*
gi 2786099445 548 VAVIVEQGG---FGSLSAVPIGKKILDAAFGLDTP 579
Cdd:COG0768 533 VAVVVENPGggaYGGTVAAPVFREIMEAYLRLLGP 567
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
8-571 |
1.23e-105 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 331.73 E-value: 1.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 8 IVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPEDVIERLSV 87
Cdd:PRK10795 29 ILLLTGVLIANLYNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGTPLALNRTIYQLEMMPEKVDNLQQTLDALRS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 88 LLHVPTEEI---HKKIDAHVGFDPIRIKQDIGPEVYTIIEEQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEISNEEL 164
Cdd:PRK10795 109 VVDLTDDDIaafRKERARSRRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYQRRYYPYGSALTHVIGYVSKINDKDV 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 165 EKRKAEG----YKSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGTKEPIAGNDLVLTIDATIQvaaeRAID 240
Cdd:PRK10795 189 ERLDKEGklanYAATHDIGKLGIERYYEDVLHGKTGYEEVEVNNRGRVIRQLHEQPPQAGHDIYLTLDLKLQ----QYIE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 241 QQLSAIGANAaaaVVMNPQTGEVLALVSRPSFDPNLFVNGISTKDWKVINENPYHPMDNKAITGEYPPGSTFKIVTGTAA 320
Cdd:PRK10795 265 TLLAGSRAAV---VVTDPRTGGILALVSTPSYDPNLFVDGISSKDYSGLLNDPNRPLINRATQGVYPPASTVKPYVAVSA 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 321 LQENVVSPNEIIYDSGrHWIIPkgnaGGE---------ALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGS 391
Cdd:PRK10795 342 LSAGVITRNTSLFDPG-WWQLP----GSEkryrdwkkwGHGRLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGH 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 392 KTGIDLPYEAEGLVPSREYKKKVYEDDWYLSETFDAAIGQGFDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVgPDGNTV 471
Cdd:PRK10795 417 YTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMTLINDGIVKVPHLLMSTA-EDGKQV 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 472 ETIKPKRIGRLDVRPEVIALVQQGLRDVTKY--GTAAAAFgAKYPVDIAGKTGTAE---------------NSHGRDHGW 534
Cdd:PRK10795 496 PWVQPHEPPVGDIHSGYWEIAKDGMYGVANRpnGTAHKYF-ASAPYKIAAKSGTAQvfglkanetynahkiAERLRDHKL 574
|
570 580 590
....*....|....*....|....*....|....*..
gi 2786099445 535 FVAYGPFNNPTIVVAVIVEQGGFGSlSAVPIGKKILD 571
Cdd:PRK10795 575 MTAFAPYNNPQVAVAIILENGGAGP-AVGTIMRQILD 610
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
254-571 |
2.26e-75 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 241.94 E-value: 2.26e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 254 VVMNPQTGEVLALVSRPSFDPNLFVNgistkdwkvinenpyhPMDNKAITGEYPPGSTFKIVTGTAALQENVVSPNEIIY 333
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPSYDPNGFIG----------------PLRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIF 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 334 DSGRHW--IIPKGNAGGEALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTGIDLPYEAEGLVPSReyk 411
Cdd:pfam00905 68 DWPGKQqgGKSIGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLTPY--- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 412 kkvyeddWYLSETFDAAIGqgfDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGpdgntveTIKPKRIGRLDVRPEVIAL 491
Cdd:pfam00905 145 -------WLEGATASFGIG---LTITPLQQAQAYAAIANGGKLVPPHLVKSIED-------KVDPKVLNKLPISKSTAEK 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 492 VQQGLRDVTKYGTAAAAfGAKYPVDIAGKTGTAE--------NSHGRDHGWFVAYGPFNNPTIVVAVIVEQGG--FGSLS 561
Cdd:pfam00905 208 VKDMLRLVVNDGTGTGT-AAVPGYKVAGKTGTAQvagpkgggYYDGAQIGWFVGYAPADNPKYAFAVLIDDPKryYGGKV 286
|
330
....*....|
gi 2786099445 562 AVPIGKKILD 571
Cdd:pfam00905 287 AAPIFKDILE 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
3-575 |
0e+00 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 684.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 3 VLGGVIVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPEDVI 82
Cdd:TIGR03423 5 VLGGLVLALFGVLAARLFYLQVIRGEEYATLSEDNRIRLVPIPPPRGLILDRNGVLLADNRPSFSLEIVPEKVDDLDATL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 83 ERLSVLLHVPTEEI---HKKIDAHVGFDPIRIKQDIGPEVYTIIEEQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEI 159
Cdd:TIGR03423 85 DRLAKLLDLDPEDIarfLKELKRSRRFEPIPLKSDLTEEEVARFAVNQYRLPGVEIEARLKRYYPYGELAAHVLGYVGEI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 160 SNEELEKRKAEGYKSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGTKEPIAGNDLVLTIDATIQVAAERAI 239
Cdd:TIGR03423 165 NEEDLERLEPANYAGGDYIGKSGIEKYYEDELRGKPGYREVEVNARGRVIRTLSRVPPVPGKDLVLTIDARLQQAAEKAL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 240 DQQlsaiganAAAAVVMNPQTGEVLALVSRPSFDPNLFVNGISTKDWKVINENPYHPMDNKAITGEYPPGSTFKIVTGTA 319
Cdd:TIGR03423 245 GGR-------RGAVVVMDPRTGEILAMVSTPSFDPNLFVDGISSKDYKALLNDPDRPLLNRAIQGVYPPGSTFKPVVALA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 320 ALQENVVSPNEIIYDSGrHWIIPKG-----NAGGEalGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTG 394
Cdd:TIGR03423 318 ALEEGVITPETRIYCPG-YFQLGGRrfrcwKRGGH--GRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFGQKTG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 395 IDLPYEAEGLVPSREYKKKVYEDDWYLSETFDAAIGQGFDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETI 474
Cdd:TIGR03423 395 IDLPGEKSGLVPSREWKRKRFGQPWYPGDTLNVSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRT 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 475 KPKRIGRLDVRPEVIALVQQGLRDVTK--YGTAAAAFgAKYPVDIAGKTGTAE---------------NSHGRDHGWFVA 537
Cdd:TIGR03423 475 EPEVLRPLPISPENLDVVREGMRDVVNgpGGTARRAR-LGLPYKMAGKTGTAQvvslkqgekydaeqiPERLRDHALFVA 553
|
570 580 590
....*....|....*....|....*....|....*...
gi 2786099445 538 YGPFNNPTIVVAVIVEQGGFGSLSAVPIGKKILDAAFG 575
Cdd:TIGR03423 554 FAPYDNPKIAVAVIVEHGGGGSSAAAPIARKIMDAYLL 591
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
1-579 |
0e+00 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 588.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 1 MHVLGGVIVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPED 80
Cdd:COG0768 14 LLLLFLLVLLLFLLLVGRLFYLQVVEGDEYAELAEENRIRTVPIPAPRGLIYDRNGNVLATNVPVYSLYADPEEVKDPEE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 81 VIERLSVLLHVPTEEIHKKIDAHVGFdPIRIKQDIGPEVYTIIeeQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEIS 160
Cdd:COG0768 94 TAEKLAKLLGLDPEELRKKLKKKSRF-PVYLKRNLSPEEAARI--RALKLPGVYVEAEYKRYYPYGELAAHVLGYVGEIN 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 161 neelekrkaegykSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLG-TKEPIAGNDLVLTIDATIQVAAERAI 239
Cdd:COG0768 171 -------------GGDGIGKSGLEKAYEDLLRGTPGKRRVEVDARGRVIRDLGeEKPPVPGKDLVLTIDSDLQKIAEEAL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 240 DQQLSAIGANAAAAVVMNPQTGEVLALVSRPSFDPNLFVNGistkdwkvinenPYHPMDNKAITGEYPPGSTFKIVTGTA 319
Cdd:COG0768 238 KKAVEEYKAKSGAVVVMDPKTGEILAMASYPSFDPNLFVGG------------PDEPLRNRAVQGTYEPGSTFKPFTAAA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 320 ALQENVVSPNEIIYDSGRHWIIPK--GNAGGEALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTGIDL 397
Cdd:COG0768 306 ALEEGVITPDTTFDCPGYYRVGGRtiRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKTGIDL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 398 PYEAEGLVPSREykkkvyedDWYLSETFDAAIGQGFdLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETiKPK 477
Cdd:COG0768 386 PGEASGLLPSPK--------RWYPGETATMSIGQGL-SVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKE-EPE 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 478 RIGRLdVRPEVIALVQQGLRDVT--KYGTAAAAFGAKYPVdiAGKTGTAEN--------SHGRDHGWFVAYGPFNNPTIV 547
Cdd:COG0768 456 VLRRV-ISPETAETVREGMEGVVnePGGTARRAAIPGYRV--AGKTGTAQVvdignggyYKGRHIASFVGFAPADNPRYA 532
|
570 580 590
....*....|....*....|....*....|....*
gi 2786099445 548 VAVIVEQGG---FGSLSAVPIGKKILDAAFGLDTP 579
Cdd:COG0768 533 VAVVVENPGggaYGGTVAAPVFREIMEAYLRLLGP 567
|
|
| PRK10795 |
PRK10795 |
penicillin-binding protein 2; Provisional |
8-571 |
1.23e-105 |
|
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain] Cd Length: 634 Bit Score: 331.73 E-value: 1.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 8 IVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPEDVIERLSV 87
Cdd:PRK10795 29 ILLLTGVLIANLYNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGTPLALNRTIYQLEMMPEKVDNLQQTLDALRS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 88 LLHVPTEEI---HKKIDAHVGFDPIRIKQDIGPEVYTIIEEQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEISNEEL 164
Cdd:PRK10795 109 VVDLTDDDIaafRKERARSRRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYQRRYYPYGSALTHVIGYVSKINDKDV 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 165 EKRKAEG----YKSGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGTKEPIAGNDLVLTIDATIQvaaeRAID 240
Cdd:PRK10795 189 ERLDKEGklanYAATHDIGKLGIERYYEDVLHGKTGYEEVEVNNRGRVIRQLHEQPPQAGHDIYLTLDLKLQ----QYIE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 241 QQLSAIGANAaaaVVMNPQTGEVLALVSRPSFDPNLFVNGISTKDWKVINENPYHPMDNKAITGEYPPGSTFKIVTGTAA 320
Cdd:PRK10795 265 TLLAGSRAAV---VVTDPRTGGILALVSTPSYDPNLFVDGISSKDYSGLLNDPNRPLINRATQGVYPPASTVKPYVAVSA 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 321 LQENVVSPNEIIYDSGrHWIIPkgnaGGE---------ALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGS 391
Cdd:PRK10795 342 LSAGVITRNTSLFDPG-WWQLP----GSEkryrdwkkwGHGRLNVTKSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGH 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 392 KTGIDLPYEAEGLVPSREYKKKVYEDDWYLSETFDAAIGQGFDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVgPDGNTV 471
Cdd:PRK10795 417 YTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMTLINDGIVKVPHLLMSTA-EDGKQV 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 472 ETIKPKRIGRLDVRPEVIALVQQGLRDVTKY--GTAAAAFgAKYPVDIAGKTGTAE---------------NSHGRDHGW 534
Cdd:PRK10795 496 PWVQPHEPPVGDIHSGYWEIAKDGMYGVANRpnGTAHKYF-ASAPYKIAAKSGTAQvfglkanetynahkiAERLRDHKL 574
|
570 580 590
....*....|....*....|....*....|....*..
gi 2786099445 535 FVAYGPFNNPTIVVAVIVEQGGFGSlSAVPIGKKILD 571
Cdd:PRK10795 575 MTAFAPYNNPQVAVAIILENGGAGP-AVGTIMRQILD 610
|
|
| spoVD_pbp |
TIGR02214 |
stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the ... |
8-574 |
8.07e-89 |
|
stage V sporulation protein D; This model describes the spoVD subfamily of homologs of the cell division protein FtsI, a penicillin binding protein. This subfamily is restricted to Bacillus subtilis and related Gram-positive species with known or suspected endospore formation capability. In these species, the functional equivalent of FtsI is desginated PBP-2B, a paralog of spoVD. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Sporulation and germination]
Pssm-ID: 131269 [Multi-domain] Cd Length: 636 Bit Score: 287.86 E-value: 8.07e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 8 IVAVIAVLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPED-----VI 82
Cdd:TIGR02214 9 FTALFLILILRLFYVQVFRGSFYKEMAEDQWTREIPIEAKRGRILDRNGNELAVSVSVDRVDLDPATIRKNKEpkqreIA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 83 ERLSVLLHVPTEEIHKKID-AHVGFDPIRIKQDIGPEVytiIEEQRD-KYPGVMIEAQPIRDYVYKTWGAHVFGYVSeis 160
Cdd:TIGR02214 89 NELARVLEMDKEKVFKRITkKNSPFVSAKLGRKIEKDK---AEKVRNlKLNGVSVSPDSKRYYPNGDFLSHVLGFTN--- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 161 neelekrkaegyksGDIVGKFGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGT--KEPIAGNDLVLTIDATIQVAAERA 238
Cdd:TIGR02214 163 --------------SDGRGLEGLELYYDKELRGLPGVRVAEYDANSLELPYAQHayVKPVDGHDLVLTIDENIQYIIERE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 239 IDQQLSAIGANAAAAVVMNPQTGEVLALVSRPSFDPNLFVNGistkdwkvineNPYHPMDNKAITGEYPPGSTFKIVTGT 318
Cdd:TIGR02214 229 ADKALRERKPKGVSIIVMNPKNGEILGMSNRPTYDPNDPRDK-----------SPDTARRNRAVSDAYEPGSTFKIITSS 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 319 AALQENVVSPNEIIYDSGRHWIIPKG----NAGGEalGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTG 394
Cdd:TIGR02214 298 AAMEEGIVKESDKFYDDGSATVGGKKikcwKPGGH--GSQTFPEVVQNSCNPGFIELGMRLGAEKLNNYILAFGFGSKTG 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 395 IDLPYEAEGLVPSREYKKKVyeddwylsETFDAAIGQGfDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETI 474
Cdd:TIGR02214 376 IDLPGEAAGILVPKKKVGPV--------DLATISFGQA-NTVTPIQLMTAVNAVANGGKLIQPHIMKEISDSQNNAVDQT 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 475 KPKRIGRLDVRPEVIALVQQGLRDVTKYGTAAAAFGAKYPVdiAGKTGTAEN-------SHGRDHGWFVAYGPFNNPTIV 547
Cdd:TIGR02214 447 FEPEVKRQVVSKETTQKLRLALETVVSKGSGKNAFIEGYRV--GGKTGTAQKvkpnggyMEGEYIVSFVGFAPADDPAVA 524
|
570 580 590
....*....|....*....|....*....|.
gi 2786099445 548 VAVIVE--QGG--FGSLSAVPIGKKILDAAF 574
Cdd:TIGR02214 525 VLVVVDnpKGVqqFGGLVAAPVFGSVFNDIL 555
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
254-571 |
2.26e-75 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 241.94 E-value: 2.26e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 254 VVMNPQTGEVLALVSRPSFDPNLFVNgistkdwkvinenpyhPMDNKAITGEYPPGSTFKIVTGTAALQENVVSPNEIIY 333
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPSYDPNGFIG----------------PLRNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIF 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 334 DSGRHW--IIPKGNAGGEALGPINFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVGSKTGIDLPYEAEGLVPSReyk 411
Cdd:pfam00905 68 DWPGKQqgGKSIGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGENAGYLTPY--- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 412 kkvyeddWYLSETFDAAIGqgfDLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGpdgntveTIKPKRIGRLDVRPEVIAL 491
Cdd:pfam00905 145 -------WLEGATASFGIG---LTITPLQQAQAYAAIANGGKLVPPHLVKSIED-------KVDPKVLNKLPISKSTAEK 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 492 VQQGLRDVTKYGTAAAAfGAKYPVDIAGKTGTAE--------NSHGRDHGWFVAYGPFNNPTIVVAVIVEQGG--FGSLS 561
Cdd:pfam00905 208 VKDMLRLVVNDGTGTGT-AAVPGYKVAGKTGTAQvagpkgggYYDGAQIGWFVGYAPADNPKYAFAVLIDDPKryYGGKV 286
|
330
....*....|
gi 2786099445 562 AVPIGKKILD 571
Cdd:pfam00905 287 AAPIFKDILE 296
|
|
| PBP_dimer |
pfam03717 |
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ... |
43-211 |
6.03e-49 |
|
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain] Cd Length: 178 Bit Score: 167.88 E-value: 6.03e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 43 PSVAPRGNFFDRNGTPLVMNRPSFTVSLLPLSGTIPED--VIERLSVLLHVPT-------EEIHKKIDAHVGFDPIRIKQ 113
Cdd:pfam03717 1 PIPAPRGEIYDRNGVVLATNKPVYSLTITPSKLKKADAlkTALKLAKLLSNYEdlddedlTERFLKMNSYKSYYPVVIKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 114 DIGPEVYTIIEEQRDKYPGVMIEAQPIRDYVYKTWGAHVFGYVSEISNEELEKRKAEGYKSGDIVGKFGLERVYDKTVRG 193
Cdd:pfam03717 81 NLSEEEVARIEENLLELPGVSIETDPVRYYPYGELAAHLLGYVGEITEEELEKYLDKGYSRGDLVGKSGLEKQYESVLRG 160
|
170
....*....|....*...
gi 2786099445 194 TDGGRQVEVDVAGKPVNN 211
Cdd:pfam03717 161 KDGVRQVEVDALGRVIRE 178
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
226-573 |
2.05e-48 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 178.58 E-value: 2.05e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 226 TIDATIQVAAERAIDQQLSAIGANAAAA--VVMNPQTGEVLALVSRPSFDPNLFvngistkdwkvinenpyhpmdNKAIT 303
Cdd:COG0744 300 TLDPKLQKAAEKAVKNVLPEGKPGGLQAalVVVDPKTGEVLAMVGGRDYGKSQF---------------------NRATQ 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 304 GEYPPGSTFKIVTGTAALqENVVSPNEIIYDS-----GRHWIIpkGNAGGEALGPINFIQALAHSDNVYFYEMGNRLGVD 378
Cdd:COG0744 359 AKRQPGSTFKPFVYAAAL-EQGYTPATTVDDEpvtfpGGGWSP--KNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLD 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 379 RLGEYARMFGVGSktgiDLPYeaeglVPSreykkkvyeddwylsetfdAAIGQGfdLVTPLQAAAIMGTIAANGDRYQPH 458
Cdd:COG0744 436 KVVDTARRLGITS----PLDP-----NPS-------------------LALGTS--EVSPLEMASAYATFANGGVYVEPH 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 459 LVQRIVGPDGNTVETIKPKRIGRLDvrPEVIALVQQGLRDVTKYGTAAAAFGAKYPVdiAGKTGTAENShgRDhGWFVAY 538
Cdd:COG0744 486 AITKVTDADGKVLYEAKPKCEQVIS--PEVAYLMTDMLQDVVTSGTGRAARLPGRPV--AGKTGTTNDN--RD-AWFVGY 558
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2786099445 539 gpfnNPTIVVAVIV-------EQGGFGSLSAVPIGKKILDAA 573
Cdd:COG0744 559 ----TPQLVTAVWVgnddnspMGYVTGGSLPAPIWRDFMEAA 596
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
5-570 |
4.75e-35 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 139.57 E-value: 4.75e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 5 GGVIVAVIAvLLLRLVYLQIYDGDYYASLADGNRIRIIPSVAPRGNFFDRNGTPLVMNRPSFTV-----SLLPLSGTIPE 79
Cdd:PRK15105 28 GCILLALVF-LLGRVAWLQVINPDMLVREGDMRSLRVQEVSTSRGMITDRSGRPLAVSVPVKAIwadpkEVHDAGGISVD 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 80 DVIERLSVLLHVPTEEIHKKIDAHVGFDPIRIKQDIGPEVYTIIeeQRDKYPGVMIEAQPIRDYVYKTWGAHVFGyVSEI 159
Cdd:PRK15105 107 DRWKALADALNIPLDQLSARINANPKGRFIYLARQVNPDMADYI--KKLKLPGIHLREESRRYYPSGEVTAHLIG-FTNV 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 160 SNEELEkrkaegyksgdivgkfGLERVYDKTVRGTDGGRQVEVDVAGKPVNNLGTKEPIAGNDLVLTIDATIQVAAERAI 239
Cdd:PRK15105 184 DSQGIE----------------GVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERLQALVYREL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 240 DQQLSAIGANAAAAVVMNPQTGEVLALVSRPSFDPNLFVNgiSTKDwkvinenpyhPMDNKAITGEYPPGSTFKIVTGTA 319
Cdd:PRK15105 248 NNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLSG--TPKD----------AMRNRAITDVFEPGSTVKPMVVMT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 320 ALQENVVSPNEII----YDSGRHWIipKGNAGGEALGPINFIQalaHSDNVyfyemgnrlGVDRLG----------EYAR 385
Cdd:PRK15105 316 ALQRGVVKENSVLntvpYRINGHEI--KDVARYSELTLTGVLQ---KSSNV---------GVSKLAlampssalvdTYSR 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 386 mFGVGSKTGIDLPYEAEGLVPSREykkkvyedDWYLSETFDAAIGQGFdLVTPLQAAAIMGTIAANGdRYQPHLVQRIVG 465
Cdd:PRK15105 382 -FGLGKATNLGLVGERSGLYPQKQ--------RWSDIERATFSFGYGL-MVTPLQLARVYATIGSYG-IYRPLSITKVDP 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 466 PDGNtvETIKPKRIGRLDVR-PEVIALVQQGlrdvtkyGTAAAAFGAKypvdIAGKTGTAEN--SHGRDHGWFVAY---- 538
Cdd:PRK15105 451 PVPG--ERVFPESIVRTVVHmMESVALPGGG-------GVKAAIKGYR----IAIKTGTAKKvgPDGRYINKYIAYtagv 517
|
570 580 590
....*....|....*....|....*....|....*.
gi 2786099445 539 GPFNNPTIVVAVIVE--QGG--FGSLSAVPIGKKIL 570
Cdd:PRK15105 518 APASQPRFALVVVINdpQAGkyYGGAVSAPVFGAIM 553
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
216-550 |
8.00e-33 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 132.38 E-value: 8.00e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 216 EPIAGNDL-------VLTIDATIQVAAERAIDQQLSAIGANAAAA-----VVMNPQTGEVLALVSRPSFDPNLFvngist 283
Cdd:TIGR02074 210 EEEYGEELytgglkiYTTLDLDAQKAAEKVLNTGLRVAGRRDGDDlqaalVAIDPDTGAVRALVGGRDYGKSQF------ 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 284 kdwkvinenpyhpmdNKAITGEYPPGSTFKIVTGTAALqENVVSPNEIIYDS-----GRHWIIPKgNAGGEALGPINFIQ 358
Cdd:TIGR02074 284 ---------------NRATQAKRQPGSTFKPFVYAAAL-EKGLTPATIVNDEpitynGNGPWSPK-NYGGGYRGNVTLRQ 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 359 ALAHSDNVYFYEMGNRLGVDRLGEYARMFGvgsktgIDLPyeaeglvpsreyKKKVYEddwylsetfdAAIGqGFDlVTP 438
Cdd:TIGR02074 347 ALAQSRNIPAVRLLQEVGLDKVVALAKRFG------ITSP------------LDPVLS----------LALG-TVE-VSP 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 439 LQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETIKPKRIGRLDvrPEVIALVQQGLRDVTKYGTAAAAFGAKYPVdiA 518
Cdd:TIGR02074 397 LEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVIS--PATAYIMTDMLKGVVESGTGRSARLPGRPV--A 472
|
330 340 350
....*....|....*....|....*....|..
gi 2786099445 519 GKTGTAENShgRDhGWFVAYgpfnNPTIVVAV 550
Cdd:TIGR02074 473 GKTGTTQNW--RD-AWFVGY----TPYYVTAV 497
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
185-565 |
8.23e-29 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 121.81 E-value: 8.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 185 RVYDKTVR-GTDGGRQVEVDVAG-----KPVNNLGTKEPIAGNDLVLTIDATIQVAAERAIDQQLSAIGANAAAAVVMNP 258
Cdd:COG5009 351 EVDDKSARvGLRDGETGTLPLEGlkwarPYINDNRRGPAPKSASDVLKPGDVIRVRPVADGGWRLRQIPEVQGALVALDP 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 259 QTGEVLALVSRPSFDPNLFvngistkdwkvinenpyhpmdNKAITGEYPPGSTFK-IVTgTAALqENVVSPNEIIYDS-- 335
Cdd:COG5009 431 HTGAVLALVGGFDFEQSKF---------------------NRATQAKRQPGSSFKpFVY-AAAL-DNGYTPATIINDApi 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 336 -------GRHWIiPKgNAGGEALGPINFIQALAHSDNVyfyeM----GNRLGVDRLGEYARMFGVGSKtgidLPYeaegl 404
Cdd:COG5009 488 vfddgggGGVWR-PK-NYSGKFYGPTTLREALEKSRNL----VtvrlLQDVGIDYVIDYAERFGIYSK----LPP----- 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 405 vpsreykkkvyeddwYLSetfdAAIGQGfdLVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETIKPKRIGR--- 481
Cdd:COG5009 553 ---------------NLS----LALGSG--EVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEdcd 611
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 482 -----------LDVRPEVIA-----LVQQGLRDVTKYGTAAAAfgAKYPVDIAGKTGTAENShgRDhGWFVAYgpfnNPT 545
Cdd:COG5009 612 aaewdgaeprlPDPAEQVIDprtayQMTSMLRGVVQRGTGRRA--RALGRDIAGKTGTTNDS--KD-AWFVGF----TPD 682
|
410 420
....*....|....*....|....*...
gi 2786099445 546 IVVAVIV--------EQGGFGSLSAVPI 565
Cdd:COG5009 683 LVAGVWVgfddprslGRGETGGRAALPI 710
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
218-536 |
2.58e-09 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 60.24 E-value: 2.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 218 IAGNDLVLTIDATIQVAAERAID---QQLSAIGANA---AAAVVMNPQTGEVLALVSrpSFDPNLfvNGIstkdwkvine 291
Cdd:PRK14850 377 FSGTKIFTTLDYISQNAAEQAVKigiPILKRKKRLKdleVAMVIIDRFSGEVRALIG--SSKPEF--NGY---------- 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 292 npyhpmdNKAITGEYPPGSTFKIVTGTAALQE------NVVSPN---EIIYDSGRHWiIPKGNaGGEALGPINFIQALAH 362
Cdd:PRK14850 443 -------NRALKARRSIGSLSKPITYLTALSQpekyhlNTWISDtpiSIKLDNGQYW-TPKNN-NFSFSGKVMLIDALIH 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 363 SDNVYFYEMGNRLGVDRLGEYARMFGVGSKTGIDLPyeaeglvpsreykkkvyeddwylsetfdaAIGQGFDLVTPLQAA 442
Cdd:PRK14850 514 SINIPTVHLSINLGLKKLVDSWILLGISSNYITPLP-----------------------------SISLGAINLTPMEVA 564
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 443 AIMGTIAANGDRYQPHLVQRIVGPDGNTVETIKPKRIGRldVRPEVIALVQQGLRDVTKYGTaAAAFGAKYP-VDIAGKT 521
Cdd:PRK14850 565 QVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHV--ESSQASYLTLYAMQQVVKSGT-AKSLGTIFKeFSLAGKT 641
|
330
....*....|....*
gi 2786099445 522 GTAENShgRDhGWFV 536
Cdd:PRK14850 642 GTTNNL--VD-SWFV 653
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
223-572 |
2.32e-06 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 50.60 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 223 LVLTIDATIQVAAERAIDQ---QLSAIGANAAAAVVMNPQTGEVLALV-SRPSFDPNLF--VNGI----Stkdwkvinen 292
Cdd:COG4953 274 IRTTLDAGLQRRLERLVRRyvrRLKQNGIHNAAVLVVDNRTGEVLAYVgSADFFDASRQgqVDMVralrS---------- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 293 pyhpmdnkaitgeypPGSTFK-IVTGtAALQENVVSPNEIIYDsgrhwiIPK-------GNAGGEALGPINFIQALAHSD 364
Cdd:COG4953 344 ---------------PGSTLKpFLYG-LALDQGLIHPETLLAD------VPTsfggyrpENFDGTFQGPVSAREALARSL 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 365 NVYFYEMGNRLGVDRLgeYARM--FGVgskTGIDLPYEAEGLvpsreykkkvyeddwylsetfdAAI--GQGfdlVTPLQ 440
Cdd:COG4953 402 NIPAVRLLEALGPARF--YARLrrAGL---RLLLPPAEHYGL----------------------SLIlgGAE---VTLEE 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 441 AAAIMGTIAANGDRYQPHLVQrivgpdgnTVETIKPKRIgrLDvrPEVIALVQQGLRDVTKYGTAAAAFGAKYPVDIAGK 520
Cdd:COG4953 452 LVGLYAALARGGEARPLRLLA--------GEPASPGRRL--LS--PGAAWLVRDILSDVPRPDGAFGWRALDSPPPIAWK 519
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 521 TGTaenSHG-RDhGWFVAYgpfnNPTIVVAVIV-------EQGGFGSLSAVPIGKKILDA 572
Cdd:COG4953 520 TGT---SYGfRD-AWAVGF----TGRYTVGVWVgnpdgtpVPGLTGAEAAAPLLFDIFDL 571
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
210-536 |
9.01e-05 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 45.53 E-value: 9.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 210 NNLGTK-EPIAGNDLVLTIDATIQVAAERAIDQQLSAIGANAAAA------VVMNPQTGEVLALV--SRPSFdpnlfvNG 280
Cdd:PRK09506 422 AKLGDKvKDLSGVKIFTTLDPVSQDAAEKAVEEGIPALKKQRKLSdletamVVVDRFSGEVRAMVggSEPQF------AG 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 281 IstkdwkvinenpyhpmdNKAITGEYPPGSTFKIVTGTAAL-QENVVSPNEIIYDSGRHWIIPKG------NAGGEALGP 353
Cdd:PRK09506 496 Y-----------------NRAMQARRSIGSLAKPATYLTALsQPDKYRLNTWIADAPISLRQPNGqvwspqNDDRRFSGR 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 354 INFIQALAHSDNVYFYEMGNRLGVDRLGEYARMFGVgsktgidlPYEAEGLVPSreykkkvyeddwylseTFDAAIGqgf 433
Cdd:PRK09506 559 VMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGV--------PKDQLNPVPA----------------MLLGALN--- 611
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786099445 434 dlVTPLQAAAIMGTIAANGDRYQPHLVQRIVGPDGNTVETIKPKriGRLDVRPEVIALVQQGLRDVTKYGTaAAAFGAKY 513
Cdd:PRK09506 612 --LTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQ--AERAVPAQAAYLTLYTMQQVVQRGT-GRQLGAKY 686
|
330 340
....*....|....*....|....
gi 2786099445 514 P-VDIAGKTGTAENShgRDhGWFV 536
Cdd:PRK09506 687 PnLHLAGKTGTTNDL--VD-SWFA 707
|
|
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