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Conserved domains on  [gi|2786564535|ref|WP_369813348|]
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DedA family protein [Veillonella sp. DNF00869]

Protein Classification

DedA family protein( domain architecture ID 11426582)

DedA family membrane protein is an inner membrane protein that may play an important role in membrane homeostasis

Gene Ontology:  GO:0016020
PubMed:  23086209|33771928

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
1-189 1.44e-51

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440351  Cd Length: 201  Bit Score: 164.25  E-value: 1.44e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   1 METYGYAAMFICMVLENANIPIPSEIILGFAGYLVFQGVFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRPVLMKYGKYiL 80
Cdd:COG0586    10 IAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRRLGRR-F 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  81 FSEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEHWKDLIEY 160
Cdd:COG0586    89 LKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENLPLVLEY 168
                         170       180
                  ....*....|....*....|....*....
gi 2786564535 161 NHELLIAMIVVFIVVAVVYGLKYWKRRKQ 189
Cdd:COG0586   169 LGRYGLVVLAIVVVLLLPLVLRLLRKRRR 197
 
Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
1-189 1.44e-51

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440351  Cd Length: 201  Bit Score: 164.25  E-value: 1.44e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   1 METYGYAAMFICMVLENANIPIPSEIILGFAGYLVFQGVFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRPVLMKYGKYiL 80
Cdd:COG0586    10 IAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRRLGRR-F 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  81 FSEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEHWKDLIEY 160
Cdd:COG0586    89 LKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENLPLVLEY 168
                         170       180
                  ....*....|....*....|....*....
gi 2786564535 161 NHELLIAMIVVFIVVAVVYGLKYWKRRKQ 189
Cdd:COG0586   169 LGRYGLVVLAIVVVLLLPLVLRLLRKRRR 197
SNARE_assoc pfam09335
SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast ...
22-148 9.99e-19

SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast member of this family localizes with the t-SNARE Tlg2.


Pssm-ID: 430535  Cd Length: 120  Bit Score: 77.69  E-value: 9.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  22 IPSEIILGFAGYLvfqgvFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRpvlmKYGKYILFSEDKFGAAEKLFNRYGGAAV 101
Cdd:pfam09335   1 IPGEVLLIAAGFL-----FGPWLGFLLALLGALLGALLAYLLGRYFGR----RSIVRRLLKEKRFKKVERLLEKYGFLAL 71
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2786564535 102 FIGRLLPGV-RTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGM 148
Cdd:pfam09335  72 LLLRLIPGVpRDLVNYAAGATRVPFRRFFLATLLGSIPWALVYVYLGY 119
PRK10847 PRK10847
DedA family protein;
6-166 6.97e-08

DedA family protein;


Pssm-ID: 182775  Cd Length: 219  Bit Score: 50.49  E-value: 6.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   6 YAAMFICMVLENANIP---IPSEIILGFAGYLVFQGVFDLNTAIIVG--VVAGIVGSVLSYWLGEYGGRPVLMKYGKYIl 80
Cdd:PRK10847   30 YAILFLILFCETGLVVtpfLPGDSLLFVAGALASLPTNDLNVHMMVAlmLIAAIVGDAVNYTIGRLFGEKLFSNPNSKI- 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  81 FSEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEhwKDLIEY 160
Cdd:PRK10847  109 FRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGT--LPFVQD 186

                  ....*.
gi 2786564535 161 NHELLI 166
Cdd:PRK10847  187 NLKLLI 192
 
Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
1-189 1.44e-51

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440351  Cd Length: 201  Bit Score: 164.25  E-value: 1.44e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   1 METYGYAAMFICMVLENANIPIPSEIILGFAGYLVFQGVFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRPVLMKYGKYiL 80
Cdd:COG0586    10 IAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRRLGRR-F 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  81 FSEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEHWKDLIEY 160
Cdd:COG0586    89 LKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENLPLVLEY 168
                         170       180
                  ....*....|....*....|....*....
gi 2786564535 161 NHELLIAMIVVFIVVAVVYGLKYWKRRKQ 189
Cdd:COG0586   169 LGRYGLVVLAIVVVLLLPLVLRLLRKRRR 197
SNARE_assoc pfam09335
SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast ...
22-148 9.99e-19

SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast member of this family localizes with the t-SNARE Tlg2.


Pssm-ID: 430535  Cd Length: 120  Bit Score: 77.69  E-value: 9.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  22 IPSEIILGFAGYLvfqgvFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRpvlmKYGKYILFSEDKFGAAEKLFNRYGGAAV 101
Cdd:pfam09335   1 IPGEVLLIAAGFL-----FGPWLGFLLALLGALLGALLAYLLGRYFGR----RSIVRRLLKEKRFKKVERLLEKYGFLAL 71
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2786564535 102 FIGRLLPGV-RTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGM 148
Cdd:pfam09335  72 LLLRLIPGVpRDLVNYAAGATRVPFRRFFLATLLGSIPWALVYVYLGY 119
YqaA COG1238
Uncharacterized membrane protein YqaA, VTT domain [Function unknown];
2-152 1.79e-15

Uncharacterized membrane protein YqaA, VTT domain [Function unknown];


Pssm-ID: 440851  Cd Length: 162  Bit Score: 70.23  E-value: 1.79e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   2 ETYGYAAMFICMVLENANIPIPSEIILGfagYLVFQGVFDLNTAIIVGVVAGIVGSVLSYWLG----EYGGRPVLMKYGK 77
Cdd:COG1238    14 HRYGLWGLFLVSFLEATFLPIPSEVLLV---PMLLAGPERAWLLALVATLGSVLGGLVGYAIGrflfEAVGRPLLERYGK 90
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2786564535  78 yilfsEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGE 152
Cdd:COG1238    91 -----EEKLERAQAWFRRYGFWALLLAGWTPIPGDVLTIAAGVLRLPLWPFLLASLIGRGARFFLVALLLLWFGP 160
TVP38 COG0398
Uncharacterized membrane protein YdjX, related to fungal oxalate transporter, TVP38/TMEM64 ...
4-189 1.86e-15

Uncharacterized membrane protein YdjX, related to fungal oxalate transporter, TVP38/TMEM64 family [Function unknown];


Pssm-ID: 440167 [Multi-domain]  Cd Length: 209  Bit Score: 71.03  E-value: 1.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   4 YGYAAMFICMVLENAnIPIPSEIILGFAGYLvfqgvFDLNTAIIVGVVAGIVGSVLSYWLGEYGGRPVLMKygkyiLFSE 83
Cdd:COG0398    38 LAPLVFILLYALQTL-LPLPGTVLTLAAGAL-----FGPWLGTLLSLIGATLGALLAFLLARYLGRDFVER-----LLGK 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  84 DKFGAAEKLFNRYGGAAVFIGRLLPGV-RTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEHWkdlieyNH 162
Cdd:COG0398   107 PRLKRLDRLLERNGFLAVFLLRLIPVFpFDLVNYAAGLTGVRLRTFLLATLLGMLPGTLVYVYLGAGLASLN------SL 180
                         170       180
                  ....*....|....*....|....*..
gi 2786564535 163 ELLIAMIVVFIVVAVVYGLKYWKRRKQ 189
Cdd:COG0398   181 GLLLALALLALLALLGLLLRRLRRRLK 207
PRK10847 PRK10847
DedA family protein;
6-166 6.97e-08

DedA family protein;


Pssm-ID: 182775  Cd Length: 219  Bit Score: 50.49  E-value: 6.97e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535   6 YAAMFICMVLENANIP---IPSEIILGFAGYLVFQGVFDLNTAIIVG--VVAGIVGSVLSYWLGEYGGRPVLMKYGKYIl 80
Cdd:PRK10847   30 YAILFLILFCETGLVVtpfLPGDSLLFVAGALASLPTNDLNVHMMVAlmLIAAIVGDAVNYTIGRLFGEKLFSNPNSKI- 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786564535  81 FSEDKFGAAEKLFNRYGGAAVFIGRLLPGVRTFISFPAGVAKYPMTPFVIWTTLGTIPWTILLVWLGMKLGEhwKDLIEY 160
Cdd:PRK10847  109 FRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGT--LPFVQD 186

                  ....*.
gi 2786564535 161 NHELLI 166
Cdd:PRK10847  187 NLKLLI 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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