|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
209-446 |
2.96e-52 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 175.87 E-value: 2.96e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 209 ELKQELTKQKERDQSQKELMSVISHELKSPITAVMGQLDGMIHGVGIYK-DRDTYLKKSYEMVQNINELTEELNDVAKLQ 287
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPeERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 288 NSHFEPHIVKIELSHLIHTIIQKADYFVQMKRLYLHTNIQPN-INISADKKYIETAISNIISNAIQYTIDRQHVYITLYE 366
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPElPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 367 KPNGYILEVMNTGSQIEEEKLARVFEPYYRacGGSHSAVKGSGFGLYMVKQILDKHHfpyG---IQNTS-HGVKFAITFP 442
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYR--GDNSRGEGGTGLGLAIVKRIVEAHG---GtiwVESEPgGGTTFTVTLP 235
|
....
gi 2786659469 443 KSVS 446
Cdd:COG2205 236 LAES 239
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
130-444 |
8.04e-51 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 176.67 E-value: 8.04e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 130 AMEELAPYIGIAIASLSILSSIIYTKFIAKPYVQMDATLKEIMNLKFEDGAIMAAGTIQMRNRATEVKQVVTTLQKKNEE 209
Cdd:COG5002 71 LLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAA 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 210 LKQELTKQKERDQSQKELMSVISHELKSPITAVMGQLDGMIHGVGI-YKDRDTYLKKSYEMVQNINELTEELNDVAKLQN 288
Cdd:COG5002 151 VERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADdPEERREYLEIILEEAERLSRLVNDLLDLSRLES 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 289 SHFEPHIVKIELSHLIHTIIQKADYFVQMKRLYLHTNIQP-NINISADKKYIETAISNIISNAIQYTIDRQHVYITLYEK 367
Cdd:COG5002 231 GELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEdPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREE 310
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2786659469 368 PNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDKHHFPYGIQNT-SHGVKFAITFPKS 444
Cdd:COG5002 311 DDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEpGKGTTFTITLPLA 388
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
218-444 |
7.84e-48 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 167.01 E-value: 7.84e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 218 KERDQSQKELMSVISHELKSPITAVMGQLDGMIHGVGiyKDRDTYLKKSYEMVQNINELTEELNDVAKLQNSHFEPHIVK 297
Cdd:COG0642 104 EEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELD--EEQREYLETILRSADRLLRLINDLLDLSRLEAGKLELEPEP 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 298 IELSHLIHTIIQKADYFVQMKRLYLHTNIQPNI-NISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVM 376
Cdd:COG0642 182 VDLAELLEEVVELFRPLAEEKGIELELDLPDDLpTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVRISVE 261
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2786659469 377 NTGSQIEEEKLARVFEPYYRAcgGSHSAVKGSGFGLYMVKQILDKHHFPYGIQNTS-HGVKFAITFPKS 444
Cdd:COG0642 262 DTGPGIPPEDLERIFEPFFRT--DPSRRGGGTGLGLAIVKRIVELHGGTIEVESEPgKGTTFTVTLPLA 328
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
217-444 |
4.85e-28 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 115.06 E-value: 4.85e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 217 QKERDQSQKELMSVISHELKSPITAVMGQLDGMIHGVG--IYKDRDTyLKKSYEM----VQNINELTEELNDVAKLQnsh 290
Cdd:COG5000 194 RAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLAdkLEEDRED-LERALDTiirqVDRLKRIVDEFLDFARLP--- 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 291 fEPHIVKIELSHLIHTIIQkadyfvqmkrLYLHTNIQPNIN-----------ISADKKYIETAISNIISNAIQYTIDRQH 359
Cdd:COG5000 270 -EPQLEPVDLNELLREVLA----------LYEPALKEKDIRleldldpdlpeVLADRDQLEQVLINLLKNAIEAIEEGGE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 360 VYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYracggSHSAvKGSGFGLYMVKQILDKHHFPYGIQNTS-HGVKFA 438
Cdd:COG5000 339 IEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFF-----TTKP-KGTGLGLAIVKKIVEEHGGTIELESRPgGGTTFT 412
|
....*.
gi 2786659469 439 ITFPKS 444
Cdd:COG5000 413 IRLPLA 418
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
178-444 |
1.10e-24 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 104.50 E-value: 1.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 178 DGAIMAAGTIQMRNRATEVKQVVTTLQKKNEELKQELTKQKERD----QSQK-----ELMSVISHELKSPITAVMGQLDG 248
Cdd:COG4191 87 LLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRELQeqlvQSEKlaalgELAAGIAHEINNPLAAILGNAEL 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 249 MIHGVGIYKDRDT---YLKKSYEMVQNINELTEELNDVAKLQNSHFEPhivkIELSHLIHTIIQKADYFVQMKRLYLHTN 325
Cdd:COG4191 167 LRRRLEDEPDPEElreALERILEGAERAAEIVRSLRAFSRRDEEEREP----VDLNELIDEALELLRPRLKARGIEVELD 242
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 326 IQPNI-NISADKKYIETAISNIISNAIQYTIDRQH--VYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYY--RACGg 400
Cdd:COG4191 243 LPPDLpPVLGDPGQLEQVLLNLLINAIDAMEEGEGgrITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFttKPVG- 321
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2786659469 401 shsavKGSGFGLYMVKQILDKHHfpyG---IQNT-SHGVKFAITFPKS 444
Cdd:COG4191 322 -----KGTGLGLSISYGIVEKHG---GrieVESEpGGGTTFTITLPLA 361
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
130-444 |
6.81e-22 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 97.93 E-value: 6.81e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 130 AMEELAPYIGIAIASLSILSSIIYTKFIAKPYVQMDATLKEIMNLKFEDGAIMAAGTIQMRNRATEVKQVVTTLQKKNEE 209
Cdd:COG4251 195 LLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAE 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 210 LKQeltKQKERDQsqkeLMSVISHELKSPITAVMGQLDgMI---HGVGIYKDRDTYLKKSYEMVQNINELTEELNDVAKL 286
Cdd:COG4251 275 LER---SNEELEQ----FAYVASHDLREPLRKISGFSQ-LLeedYGDKLDEEGREYLERIRDAAERMQALIDDLLAYSRV 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 287 QNShfEPHIVKIELSHLIHTIIqkADYFVQMKRLYLHTNIQPNINISADKKYIETAISNIISNAIQYTIDRQ--HVYITL 364
Cdd:COG4251 347 GRQ--ELEFEPVDLNELLEEVL--EDLEPRIEERGAEIEVGPLPTVRGDPTLLRQVFQNLISNAIKYSRPGEppRIEIGA 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 365 YEKPNGYILEVMNTGSQIEEEKLARVFEPYYRacGGSHSAVKGSGFGLYMVKQILDKHHfpyG-IQNTS---HGVKFAIT 440
Cdd:COG4251 423 EREGGEWVFSVRDNGIGIDPEYAEKIFEIFQR--LHSRDEYEGTGIGLAIVKKIVERHG---GrIWVESepgEGATFYFT 497
|
....
gi 2786659469 441 FPKS 444
Cdd:COG4251 498 LPKA 501
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
334-444 |
9.32e-22 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 89.63 E-value: 9.32e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 334 ADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRAcGGSHSAVKGSGFGLY 413
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRT-DKRSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|..
gi 2786659469 414 MVKQILDKHHFPYGIQNTS-HGVKFAITFPKS 444
Cdd:smart00387 80 IVKKLVELHGGEISVESEPgGGTTFTITLPLE 111
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
231-443 |
3.32e-18 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 86.75 E-value: 3.32e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 231 ISHELKSPITAVMGQLDGMIHGVGIYKDRDTYLKKSYEMVQNINELTEELNDVAKLQNSHFEPHIVKIELSHLIHTIIQK 310
Cdd:PRK09835 269 IAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDF 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 311 ADYFVQMKRLYLHTNIQPNInISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARV 390
Cdd:PRK09835 349 FEAWAEERGVELRFVGDPCQ-VAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRL 427
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2786659469 391 FEPYYRACGGSHSAVKGSGFGLYMVKQILDKHHFPYGIQNTSHGVKFAITFPK 443
Cdd:PRK09835 428 FDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLPR 480
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
334-442 |
2.23e-17 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 77.41 E-value: 2.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 334 ADKKYIETAISNIISNAIQYTIDRQHVYITLyEKPNGYILEVMNTGSQIEEEKLARVFEPYYRAcggSHSAVKGSGFGLY 413
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTL-SEGGELTLTVEDNGIGIPPEDLPRIFEPFSTA---DKRGGGGTGLGLS 76
|
90 100 110
....*....|....*....|....*....|
gi 2786659469 414 MVKQILDKHHFPYGIQNTS-HGVKFAITFP 442
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPgGGTTVTLTLP 106
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
202-423 |
8.61e-17 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 81.43 E-value: 8.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 202 TLQKKNEElkqELTkQKERDQSQKELMSVISHELKSPITAVMG--QLDGMihgvgiyKDRDTYLKKSYEMVQN----INE 275
Cdd:COG3852 117 TERKRLER---ELR-RAEKLAAVGELAAGLAHEIRNPLTGIRGaaQLLER-------ELPDDELREYTQLIIEeadrLNN 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 276 LTEELNDVAKLQNSHFEPhivkIELSHLIHTIIQ--KADYfvqMKRLYLHTNIQPNI-NISADKKYIETAISNIISNAIQ 352
Cdd:COG3852 186 LVDRLLSFSRPRPPEREP----VNLHEVLERVLEllRAEA---PKNIRIVRDYDPSLpEVLGDPDQLIQVLLNLVRNAAE 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 353 YTIDRQHVYITLY---------EKPNGYI-LEVMNTGSQIEEEKLARVFEPYY--RAcggshsavKGSGFGLYMVKQILD 420
Cdd:COG3852 259 AMPEGGTITIRTRverqvtlggLRPRLYVrIEVIDNGPGIPEEILDRIFEPFFttKE--------KGTGLGLAIVQKIVE 330
|
...
gi 2786659469 421 KHH 423
Cdd:COG3852 331 QHG 333
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
176-442 |
1.92e-16 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 81.55 E-value: 1.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 176 FEDGAIMAAGTIQMRNRATEVKQVVTTLQKKNEELK-QELTKQKERDQSQKELMSVISHELKSPITAVMGQldgmihgVG 254
Cdd:PRK11360 341 RDRTIELSVSTSLLHNTHGEMIGALVIFSDLTERKRlQRRVARQERLAALGELVAGVAHEIRNPLTAIRGY-------VQ 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 255 IYKDRDT------YLKKSYEMVQNINELTEELNDVAKLQnshfEPHIVKIELSHLIHTIIQKADYFVQMKRLYLHTNIQP 328
Cdd:PRK11360 414 IWRQQTSdppsqeYLSVVLREVDRLNKVIDQLLEFSRPR----ESQWQPVSLNALVEEVLQLFQTAGVQARVDFETELDN 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 329 NI-NISADKKYIETAISNIISNAIQYTIDRQHVYI-TLYEKPNGYILEVMNTGSQIEEEKLARVFEPYY--RAcggshsa 404
Cdd:PRK11360 490 ELpPIWADPELLKQVLLNILINAVQAISARGKIRIrTWQYSDGQVAVSIEDNGCGIDPELLKKIFDPFFttKA------- 562
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2786659469 405 vKGSGFGLYMVKQILDKHHfpyG-IQNTSH---GVKFAITFP 442
Cdd:PRK11360 563 -KGTGLGLALSQRIINAHG---GdIEVESEpgvGTTFTLYLP 600
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
220-443 |
9.95e-16 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 78.90 E-value: 9.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 220 RDQSQKELM--------SVISHELKSPITAVMGQLDGMIHGVGIYKDRDTYLKKSYEMVQNINELTEELndvakLQNSHF 291
Cdd:PRK11006 192 RDVTQMHQLegarrnffANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQL-----LTLSKI 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 292 E--PHIV---KIELSHLIHTIIQKADYFVQmKRLYLHTNIQPNINISADKKYIETAISNIISNAIQYTIDRQHVYITLYE 366
Cdd:PRK11006 267 EaaPTIDlneKVDVPMMLRVLEREAQTLSQ-GKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQR 345
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2786659469 367 KPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDKHHFPYGIQNTSH-GVKFAITFPK 443
Cdd:PRK11006 346 VPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGkGTRFSFVLPE 423
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-442 |
9.94e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 70.01 E-value: 9.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAvKGSGFGLYM 414
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQ-ESTGMGLYL 80
|
90 100
....*....|....*....|....*....
gi 2786659469 415 VKQILDK-HHFPYGIQNTSHGVKFAITFP 442
Cdd:cd16948 81 VKKLCDKlGHKIDVESEVGEGTTFTITFP 109
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
189-444 |
1.41e-14 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 75.54 E-value: 1.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 189 MRNRATEVKQVVTTLQkkneelkqELTKQKERDQ--SQKELMSV-------ISHELKSPITAVMGQLDGMihGVGIyKDR 259
Cdd:COG5805 251 LIDTDGSVKGILVILR--------DITEKKEAEElmARSEKLSIagqlaagIAHEIRNPLTSIKGFLQLL--QPGI-EDK 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 260 DTYLKKSYEMVQNINELTEELNDVAKLQNSHFEPHIVKIELSHLIhTIIQkADYFVQMKRLYLHTNiQPNINISADKKYI 339
Cdd:COG5805 320 EEYFDIMLSELDRIESIISEFLALAKPQAVNKEKENINELIQDVV-TLLE-TEAILHNIQIRLELL-DEDPFIYCDENQI 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 340 ETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRacggshSAVKGSGFGLYMVKQIL 419
Cdd:COG5805 397 KQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFT------TKEKGTGLGLMVSYKII 470
|
250 260
....*....|....*....|....*.
gi 2786659469 420 DKHHFPYGI-QNTSHGVKFAITFPKS 444
Cdd:COG5805 471 ENHNGTIDIdSKVGKGTTFTITLPLS 496
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
233-444 |
1.65e-14 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 75.27 E-value: 1.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 233 HELKSPITAVMG--QL--DGMIHgvgiyKDRDTYLKKSYEMVQNINELTEELNDVAKLQNSHFEPHIVKIELSHLIHTII 308
Cdd:PRK11100 265 HELKSPLAAIRGaaELlqEDPPP-----EDRARFTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELV 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 309 QKADYFVQMKRLYLHTNIqPNINISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLA 388
Cdd:PRK11100 340 EAREAQAAAKGITLRLRP-DDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALP 418
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 389 RVFEPYY---RacggSHSAVKGSGFGLYMVKQILDKHHFPYGIQN-TSHGVKFAITFPKS 444
Cdd:PRK11100 419 RIFERFYslpR----PANGRKSTGLGLAFVREVARLHGGEVTLRNrPEGGVLATLTLPRH 474
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
193-442 |
2.84e-14 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 74.67 E-value: 2.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 193 ATEVKQVVTTLQKkNEelkqeltkqkerdQSQKELMSVISHELKSPITAVMGQLDGMIHGVgiykdRDTYLKKSYEMVQN 272
Cdd:PRK10549 223 AQDFNQLASTLEK-NE-------------QMRRDFMADISHELRTPLAVLRGELEAIQDGV-----RKFTPESVASLQAE 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 273 INELTEELNDVAKLQNSH---FEPHIVKIELSHLIHTIIQKADYFVQMKRLYLHTNIQPNINISADKKYIETAISNIISN 349
Cdd:PRK10549 284 VGTLTKLVDDLHQLSLSDegaLAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLEN 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 350 AIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDKH------- 422
Cdd:PRK10549 364 SLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHngriiaa 443
|
250 260
....*....|....*....|
gi 2786659469 423 HFPYGiqntshGVKFAITFP 442
Cdd:PRK10549 444 HSPFG------GVSITVELP 457
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-444 |
4.97e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 68.00 E-value: 4.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQI 418
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*..
gi 2786659469 419 LDKHHFPYGIQNT-SHGVKFAITFPKS 444
Cdd:cd16952 81 MSRHDARLLIASElGKGSRFTCLFPSS 107
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
202-446 |
5.25e-14 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 73.86 E-value: 5.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 202 TLQKKNEELKQeltkQKERDQSQKELMSVISHELKSPITAVMGQLDGMIHGvgIYKDRDTYLKKSYEMVQNINELTEELN 281
Cdd:COG5809 252 TERKKLEELLR----KSEKLSVVGELAAGIAHEIRNPLTSLKGFIQLLKDT--IDEEQKTYLDIMLSELDRIESIISEFL 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 282 DVAKLQNSHFEPhivkIELSHLIHTIIQkadyFVQ----MKRLYLHTNIQPNIN-ISADKKYIETAISNIISNAIQYTID 356
Cdd:COG5809 326 VLAKPQAIKYEP----KDLNTLIEEVIP----LLQpqalLKNVQIELELEDDIPdILGDENQLKQVFINLLKNAIEAMPE 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 357 RQHVYITLYEKPNGYI-LEVMNTGSQIEEEKLARVFEPYYRacggshSAVKGSGFGLYMVKQILDKHHFPYGIQNTSH-G 434
Cdd:COG5809 398 GGNITIETKAEDDDKVvISVTDEGCGIPEERLKKLGEPFYT------TKEKGTGLGLMVSYKIIEEHGGKITVESEVGkG 471
|
250
....*....|..
gi 2786659469 435 VKFAITFPKSVS 446
Cdd:COG5809 472 TTFSITLPIKLS 483
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
165-444 |
6.19e-14 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 72.96 E-value: 6.19e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 165 DATLKEIMNLKFEDGAIMAAGTIQMRNRAT-----EVKQVVTTLQKKNE--ELKQELTKQKERDqsqkELMSVISHELKS 237
Cdd:COG3290 127 DEVLAEVLETGERDEEILLNGRVLVVNRVPirddgRVVGAVATFRDRTEleRLEEELEGVKELA----EALRAQRHDFRN 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 238 PITAVMGQLDgmihgvgiykdrdtyLKKSYEMVQNINELTEELNDVAKLQNSHFEPHIVKIELShlihtiiqkaDYFVQM 317
Cdd:COG3290 203 HLHTISGLLQ---------------LGEYDEALEYIDEISEELQELIDSLLSRIGNPVLAALLL----------GKAARA 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 318 KRLYLHTNIQPNINISADKKY---IETAISNIISNAIQYT----IDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARV 390
Cdd:COG3290 258 RERGIDLTIDIDSDLPDLPLSdtdLVTILGNLLDNAIEAVeklpEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKI 337
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2786659469 391 FEPYYracggSHSAVKGSGFGLYMVKQILDKHHfpyG----IQNTSHGVKFAITFPKS 444
Cdd:COG3290 338 FERGF-----STKLGEGRGLGLALVKQIVEKYG---GtievESEEGEGTVFTVRLPKE 387
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
223-422 |
2.90e-13 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 71.17 E-value: 2.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 223 SQKELMSVISHELKSPITAV---MGQLDGMIHGVGIYKDRDtylkksyemVQNINELTEELNDVAKLQNSHFEPHIVKIE 299
Cdd:PRK10604 211 SKKQLIDGIAHELRTPLVRLryrLEMSDNLSAAESQALNRD---------IGQLEALIEELLTYARLDRPQNELHLSEPD 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 300 LSHLIHTIIQKADYFVQMKRLYLHTNIQPNInISADKKYIETAISNIISNAIQYTidRQHVYITLYEKPNGYILEVMNTG 379
Cdd:PRK10604 282 LPAWLSTHLADIQAVTPEKTVRLDTPHQGDY-GALDMRLMERVLDNLLNNALRYA--HSRVRVSLLLDGNQACLIVEDDG 358
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2786659469 380 SQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDKH 422
Cdd:PRK10604 359 PGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAM 401
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
326-434 |
4.32e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 65.50 E-value: 4.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 326 IQPNINISADKKYIETAISNIISNAIQYTIDRQHVYITLyEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGgshSAV 405
Cdd:cd16940 1 SAADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKL-SADDGAVIRVEDNGPGIDEEELEALFERFYRSDG---QNY 76
|
90 100
....*....|....*....|....*....
gi 2786659469 406 KGSGFGLYMVKQILDKHHFPYGIQNTSHG 434
Cdd:cd16940 77 GGSGLGLSIVKRIVELHGGQIFLGNAQGG 105
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
342-442 |
1.13e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 63.94 E-value: 1.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 342 AISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAvkGSGFGLYMVKQILDK 421
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTE--GAGLGLSIAKAIIEL 81
|
90 100
....*....|....*....|...
gi 2786659469 422 H--HFPYGIQNtsHGVKFAITFP 442
Cdd:cd16923 82 HggSASAEYDD--NHDLFKVRLP 102
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-434 |
9.32e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 61.32 E-value: 9.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAvKGSGFGLYM 414
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSG-GHYGMGLYI 79
|
90 100
....*....|....*....|
gi 2786659469 415 VKQILDKHHFPYGIQNTSHG 434
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQKG 99
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
203-427 |
2.37e-11 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 64.97 E-value: 2.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 203 LQKKNEELKQELtkqkerdQSQKELMSVISHELKSPITAV--------MGQLDGMihGVGIYKDRDTYLKKSYEMVQNIN 274
Cdd:PRK09303 137 LRQENETLLEQL-------KFKDRVLAMLAHDLRTPLTAAslaletleLGQIDED--TELKPALIEQLQDQARRQLEEIE 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 275 ELTEELNDVAKLQNSHFEPHIVKIELSHLIHTIIQKADYFVQMKRLYLHTNIQPNI-NISADKKYIETAISNIISNAIQY 353
Cdd:PRK09303 208 RLITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIPSDLpSVYADQERIRQVLLNLLDNAIKY 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2786659469 354 TIDRQHVYITLYEKPNGYI-LEVMNTGSQIEEEKLARVFEPYYRAcggSHSAVK-GSGFGLYMVKQILDKHhfpYG 427
Cdd:PRK09303 288 TPEGGTITLSMLHRTTQKVqVSICDTGPGIPEEEQERIFEDRVRL---PRDEGTeGYGIGLSVCRRIVRVH---YG 357
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
198-445 |
2.72e-11 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 65.91 E-value: 2.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 198 QVVTTLQKKNEELKQELTKQKERDQSQKELMSVISHELKSPITAVMGQLDgMIHGVGIYKD-RDTYLKKSYEMVQNINEL 276
Cdd:PRK09959 686 QDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLE-LLSGSGLSKEqRVEAISLAYATGQSLLGL 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 277 TEELNDVAKLQNSHFEPHIVKIELSHLIHTIIQKADYFVQMKRLYL--HTNIQPNINISADKKYIETAISNIISNAIQYT 354
Cdd:PRK09959 765 IGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALscSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFT 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 355 -------------IDRQHVYITlyekpngyiLEVMNTGSQIEEEKLARVFEPYYRACGGSHSAvkGSGFGLYMVKQILDK 421
Cdd:PRK09959 845 tegavkittslghIDDNHAVIK---------MTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKN 913
|
250 260
....*....|....*....|....*..
gi 2786659469 422 HHFPYGIQntSH---GVKFAITFPKSV 445
Cdd:PRK09959 914 MQGDLSLE--SHpgiGTTFTITIPVEI 938
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
216-444 |
3.99e-11 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 64.55 E-value: 3.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 216 KQKERDQSQkeLMSVISHELKSPITAV------MGQldgmihgvgiykdRDTYLKKSyemvqnINELTEELN-------D 282
Cdd:PRK09467 223 KQLEDDRTL--LMAGVSHDLRTPLTRIrlatemMSE-------------EDGYLAES------INKDIEECNaiieqfiD 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 283 VAKL-QNSHFEPhivkIELSHLIHTIIQ-KADYFVQmkrlyLHTNIQPN-INISADKKYIETAISNIISNAIQYTIDRqh 359
Cdd:PRK09467 282 YLRTgQEMPMEM----ADLNALLGEVIAaESGYERE-----IETALQPGpIEVPMNPIAIKRALANLVVNAARYGNGW-- 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 360 VYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYR---ACGGShsavkGSGFGLYMVKQILDKHHFPYGIQNTSH-GV 435
Cdd:PRK09467 351 IKVSSGTEGKRAWFQVEDDGPGIPPEQLKHLFQPFTRgdsARGSS-----GTGLGLAIVKRIVDQHNGKVELGNSEEgGL 425
|
....*....
gi 2786659469 436 KFAITFPKS 444
Cdd:PRK09467 426 SARAWLPLT 434
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
219-422 |
1.12e-10 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 63.90 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 219 ERDQSQKELMSVISHELKSPITAVMGQLDgmIHGVGIYKDRDTYLKKSYEMVQNI---NELTEELNDVAKLQNSHFEPHI 295
Cdd:PRK10490 659 EREQLRNALLAALSHDLRTPLTVLFGQAE--ILTLDLASEGSPHARQASEIRQQVlntTRLVNNLLDMARIQSGGFNLRK 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 296 VKIELSHLIHTIIQKADYfvQMKRLYLHTNIQPNIN-ISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILE 374
Cdd:PRK10490 737 EWLTLEEVVGSALQMLEP--GLSGHPINLSLPEPLTlIHVDGPLFERVLINLLENAVKYAGAQAEIGIDAHVEGERLQLD 814
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2786659469 375 VMNTGSQIEEEKLARVFEPYYRacGGSHSAVKGSGFGLYMVKQILDKH 422
Cdd:PRK10490 815 VWDNGPGIPPGQEQLIFDKFAR--GNKESAIPGVGLGLAICRAIVEVH 860
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
196-412 |
1.14e-10 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 63.89 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 196 VKQVVTTLQKKNEELKQELT---KQKERDQSQK-ELMSVISHELKSPITAVMGQLDGMIHGVGIYKDR---DTYLKKSYE 268
Cdd:PRK15347 366 LNEQYDTLENKVAERTQALAeakQRAEQANKRKsEHLTTISHEIRTPLNGVLGALELLQNTPLTAEQMdlaDTARQCTLS 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 269 MVQNINELTeelnDVAKLQNSHFEPHIVKIELSHLI----HTIIQKAdyfvQMKRLYLHTNIQPNINISA--DKKYIETA 342
Cdd:PRK15347 446 LLAIINNLL----DFSRIESGQMTLSLEETALLPLLdqamLTIQGPA----QSKSLTLRTFVGAHVPLYLhlDSLRLRQI 517
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2786659469 343 ISNIISNAIQYTidrQHVYITLY--EKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGgsHSAvkGSGFGL 412
Cdd:PRK15347 518 LVNLLGNAVKFT---ETGGIRLRvkRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADT--HSQ--GTGLGL 582
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-442 |
1.19e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 58.24 E-value: 1.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYM 414
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100 110
....*....|....*....|....*....|....*
gi 2786659469 415 VKQILDKH-------HFPYGiqntshGVKFAITFP 442
Cdd:cd16946 81 CHNIALAHggtisaeHSPLG------GLRLVLTLP 109
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-422 |
4.74e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 56.30 E-value: 4.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAIQYTidRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRacGGSHSAVKGSGFGLYMVKQI 418
Cdd:cd16950 1 LKRVLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYR--GDNARGTSGTGLGLAIVQRI 76
|
....
gi 2786659469 419 LDKH 422
Cdd:cd16950 77 SDAH 80
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-435 |
4.78e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 56.70 E-value: 4.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYY---RAcggsHSAVKGSGFG 411
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYslpRP----HSGQKSTGLG 76
|
90 100
....*....|....*....|....
gi 2786659469 412 LYMVKQILDKHHFPYGIQNTSHGV 435
Cdd:cd16945 77 LAFVQEVAQLHGGRITLRNRPDGV 100
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
323-421 |
5.15e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 57.14 E-value: 5.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 323 HTNI-QPNINISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGS 401
Cdd:cd16947 4 EINIpDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSR 83
|
90 100
....*....|....*....|
gi 2786659469 402 HSAVKGSGFGLYMVKQILDK 421
Cdd:cd16947 84 NSAKQGNGLGLTITKRLAES 103
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
224-423 |
9.31e-10 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 60.33 E-value: 9.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 224 QKELMSVISHELKSPITAVMGQLDGMIHGVGIYKD--R-DTYLKKSYEMvqnINELTEelndVAKLQ-NSHFEPHIVKIe 299
Cdd:PRK09470 243 QQRLLSDISHELRTPLTRLQLATALLRRRQGESKEleRiETEAQRLDSM---INDLLV----LSRNQqKNHLERETFKA- 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 300 lSHLIHTIIQKADYFV-QMKRLYLHTNIQPNINISADKKYIETAISNIISNAIQYTidRQHVYITLYEKPNGYILEVMNT 378
Cdd:PRK09470 315 -NSLWSEVLEDAKFEAeQMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYS--HTKIEVAFSVDKDGLTITVDDD 391
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2786659469 379 GSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDKHH 423
Cdd:PRK09470 392 GPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHR 436
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
206-412 |
1.10e-09 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 60.76 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 206 KNEELKQELTKQKER-DQSQKELMSVISHELKSPITAVMGQLDgmihgvgiykdrdtyLKKSYEMVQNINELTEELNDVA 284
Cdd:PRK10841 428 KMEESLQEMAQAAEQaSQSKSMFLATVSHELRTPLYGIIGNLD---------------LLQTKELPKGVDRLVTAMNNSS 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 285 K---------LQNSHFEPHIVKIE---------LSHLIhtiiqkADY--FVQMKRLYLHTNIQPNI--NISADKKYIETA 342
Cdd:PRK10841 493 SlllkiisdiLDFSKIESEQLKIEprefsprevINHIT------ANYlpLVVKKRLGLYCFIEPDVpvALNGDPMRLQQV 566
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2786659469 343 ISNIISNAIQYTiDRQHVYITLYEKpnGYILE--VMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGL 412
Cdd:PRK10841 567 ISNLLSNAIKFT-DTGCIVLHVRVD--GDYLSfrVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGL 635
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
139-412 |
1.83e-09 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 59.92 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 139 GIAIASLS-ILSSIIYtKFIAKPYVQMDATLKEIMNLKFED--------------GAIMAAGTIQMR--NR-----ATEV 196
Cdd:PRK11466 338 MVSLCALIlILWRVVY-RSVTRPLAEQTQALQRLLDGDIDSpfpetagvreldtiGRLMDAFRSNVHalNRhreqlAAQV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 197 KQVVTTLQKKNEELKQELTKQKERDQSQKELMSVISHELKSPITAVMGQLDGMIHGVGIYKDRDTylkksyemVQNINEL 276
Cdd:PRK11466 417 KARTAELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDD--------LRAITDS 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 277 TEEL----NDV------------AKLQNSHFEPHivkielsHLIHTIIQKADYFVQMKRLYLHTNIQPNI--NISADKKY 338
Cdd:PRK11466 489 GESLltilNDIldysaieaggknVSVSDEPFEPR-------PLLESTLQLMSGRVKGRPIRLATDIADDLptALMGDPRR 561
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2786659469 339 IETAISNIISNAIQYTiDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGShsavKGSGFGL 412
Cdd:PRK11466 562 IRQVITNLLSNALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGL 630
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
221-285 |
6.69e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 51.83 E-value: 6.69e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2786659469 221 DQSQKELMSVISHELKSPITAVMGQLDGMIHGVGIYKDRDTYLKKSYEMVQNINELTEELNDVAK 285
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
231-424 |
1.08e-08 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 56.78 E-value: 1.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 231 ISHELKSPITAvmgqldGMIhgvgiykdrdtylkkSYEMVQN-------------INELTEELNDVAKLQNSHFEPHIVK 297
Cdd:NF038389 213 IMHELKTPITK------GRI---------------VAEMLEDekqkerlisiferLESLINEFAKIEQLTSKNYKLNKKE 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 298 ielsHLIHTIIQKA-DYFVQMKRLYLHTNIQPNINISADKKYIETAISNIISNAIQYTIDRqHVYITLYEKpngyILEVM 376
Cdd:NF038389 272 ----YRLSDIIDEAiDMLMIDDSSVIIKVSLEDFKLNVDFELFSLAIKNLIDNAIKYSPDK-KVTIEIKGD----KIEFK 342
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2786659469 377 NTGSQIEEEkLARVFEPYYRacgGSHSAVKGSGFGLYMVKQILDKHHF 424
Cdd:NF038389 343 NKGEPLEEP-LEYYFEPFFK---GNEKSKSGFGLGLYIVKNILKAHGF 386
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-443 |
2.04e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 51.94 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAIQYTidRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQI 418
Cdd:cd16949 1 LARALENVLRNALRYS--PSKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 2786659469 419 LDKHHFPYGIQNTS-HGVKFAITFPK 443
Cdd:cd16949 79 IEQHGGKIKASNRKpGGLRVRIWLPA 104
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-442 |
4.43e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 48.20 E-value: 4.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAIQYTidRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQI 418
Cdd:cd16939 1 MARALDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*
gi 2786659469 419 LDKHHFPYGIQNTSH-GVKFAITFP 442
Cdd:cd16939 79 ALWHGGHVECDDSELgGACFRLTWP 103
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
223-288 |
7.79e-07 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 46.05 E-value: 7.79e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2786659469 223 SQKELMSVISHELKSPITAVMGQLDgMIHGVGIYKDRDTYLKKSYEMVQNINELTEELNDVAKLQN 288
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLE-LLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEA 65
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
335-442 |
1.07e-06 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 47.10 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQYTIDRQHVYITLYE-KPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLY 413
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKfRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 2786659469 414 MVKQILDKHHFPYGIQNTS-HGVKFAITFP 442
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPgGGALFQVELP 110
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
341-422 |
1.47e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 46.51 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 341 TAISNIISNAIQYTIDRQH----VYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPyyracGGSHSAVKGSGFGLYMVK 416
Cdd:cd16915 3 TIVGNLIDNALDALAATGApnkqVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFER-----GVSTKGQGERGIGLALVR 77
|
....*.
gi 2786659469 417 QILDKH 422
Cdd:cd16915 78 QSVERL 83
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
345-423 |
1.51e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 46.65 E-value: 1.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 345 NIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYY--RACGgshsavKGSGFGLYMVKQILDKH 422
Cdd:cd16943 10 NLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFttKPVG------EGTGLGLSLSYRIIQKH 83
|
.
gi 2786659469 423 H 423
Cdd:cd16943 84 G 84
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
223-288 |
1.64e-06 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 45.25 E-value: 1.64e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2786659469 223 SQKELMSVISHELKSPITAVMGQLDGMIHGVGIYKDRDtYLKKSYEMVQNINELTEELNDVAKLQN 288
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSRIEA 65
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
137-443 |
2.11e-06 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 49.63 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 137 YIGIAIASLSILSSIIYTKFIAKPYVQMDATLKEIMNLKFedgaimaagTIQMRNRATEVKQVVTTLQKKNEELKQELTK 216
Cdd:COG2972 161 LIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDL---------VRLEVSGNDEIGILARSFNEMVERIKELIEE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 217 QKERDQSQKELmsvishELKspitAVMGQ---------LDGMIHGVgiykdrdtYLKKSYEMVQNINELTEELNdvAKLQ 287
Cdd:COG2972 232 VYELELEKKEA------ELK----ALQAQinphflfntLNSIRWLA--------ELEDPEEAEEMLEALSKLLR--YSLS 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 288 NSHfEPHIVKIELSHLIHTI-IQKADYfvqMKRLYLHTNIQPNINISADKKYIetaISNIISNAIQYTIDRQ----HVYI 362
Cdd:COG2972 292 KGD-ELVTLEEELELIKSYLeIQKLRF---GDRLEVEIEIDEELLDLLIPKLI---LQPLVENAIEHGIEPKegggTIRI 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 363 TLYEKPNGYILEVMNTGSQIEEEKLARVFEPYyracggsHSAVKGSGFGLYMVKQILDKHHFP-YGIQNTS---HGVKFA 438
Cdd:COG2972 365 SIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-------SSKGEGRGIGLRNVRERLKLYYGEeYGLEIESepgEGTTVT 437
|
....*
gi 2786659469 439 ITFPK 443
Cdd:COG2972 438 IRIPL 442
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
207-394 |
4.64e-06 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 49.16 E-value: 4.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 207 NEELKQeltKQKERD---QSQKELMSVISHELKSPITAVMgQLDGMIHGVGIYKDRDTYLKKSYEMVQNINELTEELNDV 283
Cdd:PRK10618 433 NKKLQQ---AQREYEknqQARKAFLQNIGDELKQPLQSLA-QLAAQLRQTSDEEQQQPELDQLAEQSDVLVRLVDNIQLL 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 284 AKLQNSHFEPHIVKIELSHLIHTIIQKADYFVQMK--RLYLHTNIQPNINISADKKyietAISNIISNAIQYTIDRQHV- 360
Cdd:PRK10618 509 NMLETQDWKPEQELFSLQDLIDEVLPEVLPAIKRKglQLLIHNHLKAEQLRIGDRD----ALRKILLLLLNYAITTTAYg 584
|
170 180 190
....*....|....*....|....*....|....*....
gi 2786659469 361 YITLY-----EKPNGYILEVMNTGSQIEEEKLARVFEPY 394
Cdd:PRK10618 585 KITLEvdqdeSSPDRLTIRILDTGAGVSIKELDNLHFPF 623
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-442 |
6.59e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 44.69 E-value: 6.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAI----QYTIDRQHVYITLYEKPNGY-ILEVMNTGSQIEEEKLARVFEPYYRacggshSAVKGSGFGLY 413
Cdd:cd16920 1 IQQVLINLVRNGIeamsEGGCERRELTIRTSPADDRAvTISVKDTGPGIAEEVAGQLFDPFYT------TKSEGLGMGLS 74
|
90 100 110
....*....|....*....|....*....|...
gi 2786659469 414 MVKQILDKHHfpyG----IQNTSHGVKFAITFP 442
Cdd:cd16920 75 ICRSIIEAHG---GrlsvESPAGGGATFQFTLP 104
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
233-423 |
7.52e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 48.11 E-value: 7.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 233 HELKSPITAV--------------------MGQLDgmihgVGIykDRDTYLkksyemVQNINELT--EELNDVAKLQNSH 290
Cdd:PRK10337 246 HELRSPLAALkvqtevaqlsdddpqarkkaLLQLH-----AGI--DRATRL------VDQLLTLSrlDSLDNLQDVAEIP 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 291 FEPHIVKIELSHLIHTiiQKADyfvqmKRLYLHTNIQPNINiSADKKYIETAISNIISNAIQYTIDRQHVYITLyekpNG 370
Cdd:PRK10337 313 LEDLLQSAVMDIYHTA--QQAG-----IDVRLTLNAHPVIR-TGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTL----NA 380
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2786659469 371 YILEVMNTGSQIEEEKLARVFEPYYRACGGSHSavkGSGFGLYMVKQILDKHH 423
Cdd:PRK10337 381 RNFTVRDNGPGVTPEALARIGERFYRPPGQEAT---GSGLGLSIVRRIAKLHG 430
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-422 |
1.41e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 44.10 E-value: 1.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 343 ISNIISNAIQYTI-DRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGGSHSAVKGSGFGLYMVKQILDK 421
Cdd:cd16953 5 LRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQIIEA 84
|
.
gi 2786659469 422 H 422
Cdd:cd16953 85 H 85
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
340-415 |
1.61e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 43.91 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 340 ETAISNIISNA---------IQYTIDRQHV---YITLYEK--PNGYI-LEVMNTGSQIEEEKLARVFEPYYRACGGShsa 404
Cdd:cd16919 2 ELAILNLAVNArdampeggrLTIETSNQRVdadYALNYRDliPGNYVcLEVSDTGSGMPAEVLRRAFEPFFTTKEVG--- 78
|
90
....*....|.
gi 2786659469 405 vKGSGFGLYMV 415
Cdd:cd16919 79 -KGTGLGLSMV 88
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
219-420 |
3.34e-05 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 46.47 E-value: 3.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 219 ERDQSQKEL----------MSVISHELKSPITAVMGqLDGMIHGVGIYKDRDTYLKK---SYEMVQNInelteeLNDVA- 284
Cdd:PRK11091 268 ERKRYQDALekasrdkttfISTISHELRTPLNGIVG-LSRILLDTELTAEQRKYLKTihvSAITLGNI------FNDIId 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 285 -------KLQNS----HFEPHIVKIE-LSHLIhtiiqkadyfVQMKRLYLHTNIQPN--INISADKKYIETAISNIISNA 350
Cdd:PRK11091 341 mdkmerrKLQLDnqpiDFTDFLADLEnLSGLQ----------AEQKGLRFDLEPLLPlpHKVITDGTRLRQILWNLISNA 410
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2786659469 351 IQYTiDRQHVYITL-YEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACG--GSHSAVkGSGFGLYMVKQILD 420
Cdd:PRK11091 411 VKFT-QQGGVTVRVrYEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDshGGKPAT-GTGIGLAVSKRLAQ 481
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
345-446 |
6.19e-05 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 44.96 E-value: 6.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 345 NIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRAcggsHSAVKGSGFGLYMVKQILDKHHF 424
Cdd:PRK10755 254 NLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRM----DSRYGGIGLGLSIVSRITQLHHG 329
|
90 100
....*....|....*....|....
gi 2786659469 425 PYGIQNTS--HGVKFAITFPKSVS 446
Cdd:PRK10755 330 QFFLQNRQerSGTRAWVWLPKAQN 353
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
332-422 |
1.08e-04 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 44.39 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 332 ISADKKYIETAISNIISNAIQyTIDRQHV-YITLYEKPNGYILEVMNTGSQIEEEKLARVFEPYYRACGgshsavKGSGF 410
Cdd:PRK10364 342 IQADPDRLTQVLLNLYLNAIQ-AIGQHGViSVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKA------EGTGL 414
|
90
....*....|..
gi 2786659469 411 GLYMVKQILDKH 422
Cdd:PRK10364 415 GLAVVHNIVEQH 426
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
332-444 |
1.98e-04 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 43.90 E-value: 1.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 332 ISADKKYIETAISNIISNAIQYTIDRQHVYITLYEK--------------PNGYI-LEVMNTGSQIEEEKLARVFEPYY- 395
Cdd:PRK13837 554 VEGNPAELQQVLMNLCSNAAQAMDGAGRVDISLSRAklrapkvlshgvlpPGRYVlLRVSDTGAGIDEAVLPHIFEPFFt 633
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2786659469 396 -RAcggshsavKGSGFGLYMVKQILDKHHFPYGIQNT-SHGVKFAITFPKS 444
Cdd:PRK13837 634 tRA--------GGTGLGLATVHGIVSAHAGYIDVQSTvGRGTRFDVYLPPS 676
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-422 |
4.64e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 39.44 E-value: 4.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 335 DKKYIETAISNIISNAIQ----YTIDRQHVYITLYEKPNGYI-LEVMNTGSQIEEEKLARVFEPYYRacggshSAVKGSG 409
Cdd:cd16944 1 DTTQISQVLTNILKNAAEaiegRPSDVGEVRIRVEADQDGRIvLIVCDNGKGFPREMRHRATEPYVT------TRPKGTG 74
|
90
....*....|...
gi 2786659469 410 FGLYMVKQILDKH 422
Cdd:cd16944 75 LGLAIVKKIMEEH 87
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
339-422 |
1.35e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 38.21 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 339 IETAISNIISNAIQYTIDRQHVYITL-YEKPNG-YILEVMNTGSQIEEEKLARVFEPYY--RACGgshsavKGSGFGLYM 414
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIaARRLGGrLVLVVRDNGPGIAEEHLSRVFDPFFttKPVG------KGTGLGLSI 74
|
....*...
gi 2786659469 415 VKQILDKH 422
Cdd:cd16976 75 SYGIVEEH 82
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
112-379 |
8.86e-03 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 38.51 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 112 SIRKQQPTSSNESSSVRKAMEELAPYIG---IAIASLSILSSIIYTKF-----IAKPYVQMDATLKEIMNLKfEDGAIMA 183
Cdd:COG4192 298 QISGLVGNSREQLVALNQETAQLVQQSGillLAIALLSLLLAVLINYFyvrrrLVKRLNALSDAMAAIAAGD-LDVPIPV 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 184 AGT--IQMRNRATEV--KQVVTTLQKKNEELKQELTKQKERDQSQKEL------------MSVISHELKSPITAVMGQLd 247
Cdd:COG4192 377 DGNdeIGRIARLLRVfrDQAIEKTQELETEIEERKRIEKNLRQTQDELiqaakmavvgqtMTSLAHELNQPLNAMSMYL- 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 248 gmihgvgiYKDRDTYLKKSYEMVQN----INELTEElndVAKLQNS--HFEPHIVKIELSHLIHTIIQKADYFVQM--KR 319
Cdd:COG4192 456 --------FSAKKALEQENYAQLPTsldkIEGLIER---MDKIIKSlrQFSRKSDTPLQPVDLRQVIEQAWELVESraKP 524
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2786659469 320 LYLHTNIQPNINISADKKYIETAISNIISNAIQYTIDRQHVYITLYEKPNGYILEVMNTG 379
Cdd:COG4192 525 QQITLHIPDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNG 584
|
|
| |
