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Conserved domains on  [gi|2787362319|ref|WP_370449368|]
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MULTISPECIES: FecCD family ABC transporter permease [Corynebacterium]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 32-347 7.01e-93

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 279.65  E-value: 7.01e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  32 AVVFGSADITWSTTTQVISHHifgieldeSVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGI 111
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP--------DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 112 SAGAGAGATAVIIFGAfsGSPIAPLTFGALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSFMVFAGpDP 191
Cdd:COG0609    73 SSGAALGAVLAIVLGG--GLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DP 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 192 RAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVA 271
Cdd:COG0609   150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2787362319 272 VSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRS 347
Cdd:COG0609   230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 32-347 7.01e-93

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 279.65  E-value: 7.01e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  32 AVVFGSADITWSTTTQVISHHifgieldeSVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGI 111
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP--------DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 112 SAGAGAGATAVIIFGAfsGSPIAPLTFGALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSFMVFAGpDP 191
Cdd:COG0609    73 SSGAALGAVLAIVLGG--GLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DP 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 192 RAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVA 271
Cdd:COG0609   150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2787362319 272 VSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRS 347
Cdd:COG0609   230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 24-346 1.15e-74

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 233.19  E-value: 1.15e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  24 AIAVSLVAAVVFGSADITWSTTTQVISHHIfgieldesvPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPL 103
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGD---------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 104 ADPYLLGISAGAGAGATAVIIFgaFSGSPIAPLTFGALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSF 183
Cdd:pfam01032  72 ADPSILGISSGAALGAVLAILL--GGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 184 MVFAGpDPRAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQA 263
Cdd:pfam01032 150 LLLLL-NPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLAS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 264 VLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYL 343
Cdd:pfam01032 229 LLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYL 308


                  ...
gi 2787362319 344 MSR 346
Cdd:pfam01032 309 LLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 24-347 3.31e-71

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 224.73  E-value: 3.31e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  24 AIAVSLVAAVVFGSADITWSTTTQVISHHIFGIELDE--SVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRN 101
Cdd:TIGR03869   1 ALLASLVVAVTIGPADISVGEVWRSVAAHLGRGEGFPgvALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 102 PLADPYLLGISAGAGAGATAVIIFGAFSGSPIApltfgALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALS 181
Cdd:TIGR03869  81 PLADPYLLGLSSGASLGAVAVLVLGVAVLLPVA-----AFAGALLALAATLGLARTLGTLTPTRTILAGLAVSQLCAAVT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 182 SFMVFAGPDPRAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVL 261
Cdd:TIGR03869 156 SFVIFWSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 262 QAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFL 341
Cdd:TIGR03869 236 VALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFA 315


                  ....*.
gi 2787362319 342 YLMSRS 347
Cdd:TIGR03869 316 VLLYRS 321
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 64-348 4.36e-56

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 185.93  E-value: 4.36e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  64 ASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSGSPIApLTFGALLG 143
Cdd:PRK03784   48 PRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWA-LSLCAIAG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 144 AVMATLAVGAFATAGGgLTPLRLVLSGVVLSAAFSALSSFMVFAGPDPRAAQsVMFWMLGSVAGATWLKTLFpLIVLIAV 223
Cdd:PRK03784  127 ALLITLILLRFARRHR-LSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQ-LMYWMMGGFGGVDWRQSWL-MLALLPV 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 224 LLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAA 303
Cdd:PRK03784  204 LIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCA 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2787362319 304 LMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRSH 348
Cdd:PRK03784  284 LAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSH 328
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-344 8.20e-44

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 151.94  E-value: 8.20e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  79 ILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSGSPIapLTFGALLGAVMATLAVGAFATaG 158
Cdd:cd06550     2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYA--LGAFAFAGALAIALLVLLLAS-R 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 159 GGLTPLRLVLSGVVLSAAFSALSSFMVFAGPDprAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALA 238
Cdd:cd06550    79 GGLSPSKLILIGIVLSAFFSAGVILISLLSDD--SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 239 TGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIAR 318
Cdd:cd06550   157 FDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSR 236

                         250       260
                  ....*....|....*....|....*.
gi 2787362319 319 VVgGSQEMPLGVVTGLVGAPLFLYLM 344
Cdd:cd06550   237 TL-LPSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 32-347 7.01e-93

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 279.65  E-value: 7.01e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  32 AVVFGSADITWSTTTQVISHHifgieldeSVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGI 111
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGP--------DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGV 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 112 SAGAGAGATAVIIFGAfsGSPIAPLTFGALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSFMVFAGpDP 191
Cdd:COG0609    73 SSGAALGAVLAIVLGG--GLSALGLPLAAFLGALLAALLVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLA-DP 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 192 RAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVA 271
Cdd:COG0609   150 EQLRSIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVA 229

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2787362319 272 VSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRS 347
Cdd:COG0609   230 VAGPIGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 24-346 1.15e-74

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 233.19  E-value: 1.15e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  24 AIAVSLVAAVVFGSADITWSTTTQVISHHIfgieldesvPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPL 103
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGD---------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 104 ADPYLLGISAGAGAGATAVIIFgaFSGSPIAPLTFGALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSF 183
Cdd:pfam01032  72 ADPSILGISSGAALGAVLAILL--GGSLSLFALPLAAFIGALLAALLVYFLSRGRGGASPLRLILAGIAVSALLSALTSL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 184 MVFAGpDPRAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQA 263
Cdd:pfam01032 150 LLLLL-NPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLAS 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 264 VLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYL 343
Cdd:pfam01032 229 LLTAASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYL 308


                  ...
gi 2787362319 344 MSR 346
Cdd:pfam01032 309 LLR 311
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 24-347 3.31e-71

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 224.73  E-value: 3.31e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  24 AIAVSLVAAVVFGSADITWSTTTQVISHHIFGIELDE--SVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRN 101
Cdd:TIGR03869   1 ALLASLVVAVTIGPADISVGEVWRSVAAHLGRGEGFPgvALSRLQDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 102 PLADPYLLGISAGAGAGATAVIIFGAFSGSPIApltfgALLGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALS 181
Cdd:TIGR03869  81 PLADPYLLGLSSGASLGAVAVLVLGVAVLLPVA-----AFAGALLALAATLGLARTLGTLTPTRTILAGLAVSQLCAAVT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 182 SFMVFAGPDPRAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVL 261
Cdd:TIGR03869 156 SFVIFWSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASGRVLDAFAFGDSSAAALGVDVERTRWLLLTL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 262 QAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFL 341
Cdd:TIGR03869 236 VALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFA 315


                  ....*.
gi 2787362319 342 YLMSRS 347
Cdd:TIGR03869 316 VLLYRS 321
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 15-348 1.99e-62

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 202.39  E-value: 1.99e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  15 WIYGLVIVIAIAVSLVAAVVFGSADITWSTTTQVIshhifgieldesvpassdtiVWNLRAPRGILAAIVGAGLAVSGVA 94
Cdd:COG4139    16 LLLLLLLLLLFVLSLCAGEVWIPPTQWLSEAWQLF--------------------VWQLRLPRTLAAVLVGASLAVSGAV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  95 MQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSGSPIApLTFGALLGAVMATLAVGAFATAGggLTPLRLVLSGVVLS 174
Cdd:COG4139    76 MQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPPWL-LSLAAIAGALLVTLLLLAFARRR--LSNARLLLIGVALG 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 175 AAFSALSSFMVFAGpDPRAAQSVMFWMLGSVAGATWLKtLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSRL 254
Cdd:COG4139   153 IICSAIMTWAVYFS-SSLDLRQLMYWMMGSFGGVDWRQ-LWLLLALLPVLLWLCLQGKPLNLLLLGENQARQLGLSVHRW 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 255 RTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGL 334
Cdd:COG4139   231 RNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGVVTAT 310

                         330
                  ....*....|....
gi 2787362319 335 VGAPLFLYLMSRSH 348
Cdd:COG4139   311 LGAPVFIWLLLRRR 324
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 64-348 4.36e-56

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 185.93  E-value: 4.36e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  64 ASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSGSPIApLTFGALLG 143
Cdd:PRK03784   48 PRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWA-LSLCAIAG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 144 AVMATLAVGAFATAGGgLTPLRLVLSGVVLSAAFSALSSFMVFAGPDPRAAQsVMFWMLGSVAGATWLKTLFpLIVLIAV 223
Cdd:PRK03784  127 ALLITLILLRFARRHR-LSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQ-LMYWMMGGFGGVDWRQSWL-MLALLPV 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 224 LLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAA 303
Cdd:PRK03784  204 LIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCA 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2787362319 304 LMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRSH 348
Cdd:PRK03784  284 LAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSH 328
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
14-347 3.24e-55

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 191.21  E-value: 3.24e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  14 PWIYGLVIVIAIAVSLVAAVVFGSADITWSTTTqvishhifgieldesvpASSDTIVWNLRAPRGILAAIVGAGLAVSGV 93
Cdd:PRK10577  354 VLAWLLALGLLLLLALVVALSFGRDAHGWNWLS-----------------GQLLDALLPLRLPRLLAALLAGAMLAVAGT 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  94 AMQTLVRNPLADPYLLGISAGAGAGATAVIIFgaFSGSPIAPLTFGALLGAvMATLAVGAFATAGGGLTPLRLVLSGVVL 173
Cdd:PRK10577  417 LLQRLTRNPLASPEVLGISSGAGLGVVLALFL--VPGAGFGWLLAAALLGA-LAALALILLLARRGGFAPERLLLTGIAL 493

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 174 SAAFSALSSFMVfAGPDPRAAQsVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVSR 253
Cdd:PRK10577  494 SALFTALIQLLL-ASGDPRAAQ-LLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTR 571

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 254 LRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTG 333
Cdd:PRK10577  572 ARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAA 651

                         330
                  ....*....|....
gi 2787362319 334 LVGAPLFLYLMSRS 347
Cdd:PRK10577  652 LIGAPYFLWLLRRS 665
btuC PRK09535
cobalamin ABC transporter permease BtuC;
62-346 5.74e-51

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 173.78  E-value: 5.74e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  62 VPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIifgAFSGSPIAPLTFGAL 141
Cdd:PRK09535   83 VPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAI---VLPLAVPFGLQAAAF 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 142 LGAVMATLAVGAFATAGGGLTPLRLVLSGVVLSAAFSALSSFM-VFAGPDPRAAqsvMFWMLGSVAGATWLKTLFPLIVL 220
Cdd:PRK09535  160 AGALVAAFGVYAIATENGRTPVATLLLAGVAVQTFLGAVISYLlLHSGESLRRA---VYWLMGHLHGSTWSDVEVALPVV 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 221 IAVLLFFLVKARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLP 300
Cdd:PRK09535  237 VVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLP 316

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2787362319 301 VAALMGGLFLIWVDIIARvvGGSQEMPLGVVTGLVGAPLFLYLMSR 346
Cdd:PRK09535  317 TSALAGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLRT 360
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
13-346 4.48e-49

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 167.15  E-value: 4.48e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  13 MPWIYGLVIVIAIAVSLVAAVVFGSADITWSTttqvishhifgIELDESVPASSDTIVWNLRAPRGILAAIVGAGLAVSG 92
Cdd:PRK09777    1 MKIALVIFITLALAGCALLSLRMGVIPLPWRA-----------LLTDWQAGDEHYYVLMEYRLPRLLLALFVGAALAVSG 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  93 VAMQTLVRNPLADPYLLGISAGAGAGATAVIIFgaFSGSPIAPLTFGALLGAVMATLAVGAFAtagGGLTPLRLVLSGVV 172
Cdd:PRK09777   70 VLVQGIVRNPLASPDILGVNHAASLASVGALLL--FPSLPVMWLPLLAFIGGMAGLILLKMLA---GTHQPMKLALTGVA 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 173 LSAAFSALSSFMVFAgpDPRAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALATGESTAAAVGIDVS 252
Cdd:PRK09777  145 LSALWASLTDYLMLS--RPQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVP 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 253 RLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVT 332
Cdd:PRK09777  223 HTQFWALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLT 302

                         330
                  ....*....|....
gi 2787362319 333 GLVGAPLFLYLMSR 346
Cdd:PRK09777  303 AIIGAPWFFWLLVR 316
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
61-348 3.03e-45

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 157.55  E-value: 3.03e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  61 SVPASSDTIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGataVIIFGAFSGSPIA--PLTF 138
Cdd:PRK11228   38 HTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALA---MALTSALSPTPFAgySLAF 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 139 GALLGAVMATLAVgafATAGGGLTPL----RLVLSGVVLSAAFSALSSFMVFAGPDprAAQSVMFWMLGSVAGATW--LK 212
Cdd:PRK11228  115 IAACGGGLSWLLV---MTAGGGWRHThdrnRLILAGIALSALCMALTRITLLLAED--HAYGIFYWLAGGVSHARWqeVW 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 213 TLFPLIVLIAVLLFFLvkARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVG 292
Cdd:PRK11228  190 QLLPFVVTAVPVVLLL--ANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIG 267

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2787362319 293 ATHRVVLPVAALMGGLFLIWVDIIARVVGGSQEMPLGVVTGLVGAPLFLYLMSRSH 348
Cdd:PRK11228  268 YDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARRRG 323
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-344 8.20e-44

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 151.94  E-value: 8.20e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  79 ILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSGSPIapLTFGALLGAVMATLAVGAFATaG 158
Cdd:cd06550     2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYA--LGAFAFAGALAIALLVLLLAS-R 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 159 GGLTPLRLVLSGVVLSAAFSALSSFMVFAGPDprAAQSVMFWMLGSVAGATWLKTLFPLIVLIAVLLFFLVKARHLDALA 238
Cdd:cd06550    79 GGLSPSKLILIGIVLSAFFSAGVILISLLSDD--SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 239 TGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMGGLFLIWVDIIAR 318
Cdd:cd06550   157 FDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSR 236

                         250       260
                  ....*....|....*....|....*.
gi 2787362319 319 VVgGSQEMPLGVVTGLVGAPLFLYLM 344
Cdd:cd06550   237 TL-LPSELPVGPVTALLGAPYFLYLL 261
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
69-346 7.30e-43

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 157.31  E-value: 7.30e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  69 IVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAfsGSPIAPLTFGALLGAVMAT 148
Cdd:PRK10577   57 LLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAP--ALLALASQLAAFAGGLLAA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 149 LAVGAFAtAGGGLTPLRLVLSGVVLSAAFSALSSFMVFAGPDprAAQSVMFWMLGSVA--GATWLKTLFPLIVLIAVLLF 226
Cdd:PRK10577  135 ALVFALA-GGKRLSPLRLVLAGMVVSLYLGALTTLLLLFNEQ--YLQGLFLWGAGSLAqnDWSGVQRLLPRLLVGLLLLL 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 227 FLvkARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAALMG 306
Cdd:PRK10577  212 LL--ARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIG 289

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 2787362319 307 GLFLIWVDIIARVVGG--SQEMPLGVVTGLVGAPLFLYLMSR 346
Cdd:PRK10577  290 ALLLLLTDQLVRLLAGvgGELLPTGAVTALIGAPLLLWLLPR 331
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
68-348 2.80e-37

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 136.76  E-value: 2.80e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  68 TIVWNLRAPRGILAAIVGAGLAVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFGAFSgSPIAPLTFgALLGAVMA 147
Cdd:PRK10441   54 TIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYS-SAQEQLAM-AFAGALVA 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 148 TLAVGAFATAGGG-LTPLRLVLSGVVLSAAFSALSSFMVFAGPDprAAQSVMFWMLGS--VAGATWLKTLFPLIVLIAVL 224
Cdd:PRK10441  132 SLIVAFTGSQGGGqLSPVRLTLAGVALAAVLEGLTSGIALLNPD--VYDQLRFWQAGSldIRNLHTLKVVLIPVLIAGAT 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 225 LFFLvkARHLDALATGESTAAAVGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGATHRVVLPVAAL 304
Cdd:PRK10441  210 ALLL--SRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLL 287

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2787362319 305 MGGLFLIWVDIIARVVGGSqEMPLGVVTGLVGAPLFLYLMSRSH 348
Cdd:PRK10441  288 ATPALLLFADIIGRLLVPG-ELRVSVVSAFIGAPVLIFLVRRKT 330
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
9-346 3.74e-27

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 109.41  E-value: 3.74e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319   9 PPRFMPWIYGLVIVIAIAVSLVAAVVFGSADITwstTTQVIShhifgiELDESVPASSDTIVWNLRAPRGILAAIVGAGL 88
Cdd:PRK10440    3 YVSRRLLITCLLLLAACVAAGLWGLRSGAVTLE---TSQVFA------ALMGDAPRSMTMVVTEWRLPRVLMALLIGAAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319  89 AVSGVAMQTLVRNPLADPYLLGISAGAGAGATAVIIFgaFSGSPIApLTFGALLGAVMATLAVGAFATAGGGLTpLRLVL 168
Cdd:PRK10440   74 GVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVL--FGQDLTA-IALAAMAGGIVTSLLVWLLAWRNGIDT-FRLII 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 169 SGVVLSAAFSALSSFMVFAGpDPRAAQSVMFWMLGSVAGATWLKTL--FPLIVLIAVLLFFLVkaRHLDALATGESTAAA 246
Cdd:PRK10440  150 IGIGVRAMLVAFNTWLLLKA-SLETALTAGLWNAGSLNGLTWAKTSpsAPIIILMLIAAALLV--RRMRLLEMGDDTACA 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2787362319 247 VGIDVSRLRTQVFVLQAVLVGTLVAVSGGIGFVGLVIPHLTRILVGaTHRVVLPVAALMGGLFLIWVDIIARVVGGSQEM 326
Cdd:PRK10440  227 LGVSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSG-TARWGLTQAALCGALLLLAADLCAQQLFMPYQL 305

                         330       340
                  ....*....|....*....|
gi 2787362319 327 PLGVVTGLVGAPLFLYLMSR 346
Cdd:PRK10440  306 PVGVVTVSLGGIYLIVLLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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