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Conserved domains on  [gi|2788638439|ref|WP_370597792|]
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MULTISPECIES: N-acetyltransferase family protein [Enterobacterales]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11441181)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 9.78e-67

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


:

Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 200.61  E-value: 9.78e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIHGTASFETEPPDTHEMLARLKKIRNQALPWVVALEEEKVIGYCYLTRYRERYAYRHT 80
Cdd:COG1247     2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  81 LEDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSnNQGSLKVHQQVGFTEKGTLKDIGFKHGRWLDTVLLQ 160
Cdd:COG1247    82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                  ...
gi 2788638439 161 RNL 163
Cdd:COG1247   161 KRL 163
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 9.78e-67

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 200.61  E-value: 9.78e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIHGTASFETEPPDTHEMLARLKKIRNQALPWVVALEEEKVIGYCYLTRYRERYAYRHT 80
Cdd:COG1247     2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  81 LEDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSnNQGSLKVHQQVGFTEKGTLKDIGFKHGRWLDTVLLQ 160
Cdd:COG1247    82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                  ...
gi 2788638439 161 RNL 163
Cdd:COG1247   161 KRL 163
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 31-137 3.22e-15

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 67.93  E-value: 3.22e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  31 TEPPDTHEMLARLKKIRNQALPWVVALEEEKVIGYCYLTRYRERYayRHTLEDSIYIHPDAQRQGTGKALLRHVIAWAET 110
Cdd:pfam00583  13 PEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEP--PVGEIEGLAVAPEYRGKGIGTALLQALLEWARE 90

                          90       100
                  ....*....|....*....|....*..
gi 2788638439 111 HGYRQMIAIVgDSNNQGSLKVHQQVGF 137
Cdd:pfam00583  91 RGCERIFLEV-AADNLAAIALYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-117 3.12e-12

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 58.44  E-value: 3.12e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2788638439  53 WVVALEEEKVIGYCYLTRYRERyayRHTLE-DSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMI 117
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSG---GDTAYiGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLR 63
PRK07757 PRK07757
N-acetyltransferase;
1-118 3.59e-06

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 44.41  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIHGtasfeteppdthEMLAR-----LKKIRNqalpWVVALEEEKVIGYCYLTRYRERY 75
Cdd:PRK07757    2 MEIRKARLSDVKAIHALINVYAKKG------------LMLPRsldelYENIRD----FYVAEEEGEIVGCCALHILWEDL 65

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2788638439  76 A-YRhtledSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIA 118
Cdd:PRK07757   66 AeIR-----SLAVSEDYRGQGIGRMLVEACLEEARELGVKRVFA 104
 
Name Accession Description Interval E-value
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
1-163 9.78e-67

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 200.61  E-value: 9.78e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIHGTASFETEPPDTHEMLARLKKIRNQALPWVVALEEEKVIGYCYLTRYRERYAYRHT 80
Cdd:COG1247     2 MTIRPATPEDAPAIAAIYNEAIAEGTATFETEPPSEEEREAWFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  81 LEDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSnNQGSLKVHQQVGFTEKGTLKDIGFKHGRWLDTVLLQ 160
Cdd:COG1247    82 AEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLAD-NEASIALYEKLGFEEVGTLPEVGFKFGRWLDLVLMQ 160


                  ...
gi 2788638439 161 RNL 163
Cdd:COG1247   161 KRL 163
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-161 2.54e-22

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 87.75  E-value: 2.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   6 AEEKHIPAICDIYAH-HVIHGTASFETEPPDTHEMLARLKKIRNQ--ALPWVVAL-EEEKVIGYCYLTRYRERyayRHTL 81
Cdd:COG1670    13 LRPEDAEALAELLNDpEVARYLPGPPYSLEEARAWLERLLADWADggALPFAIEDkEDGELIGVVGLYDIDRA---NRSA 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  82 EDSIYIHPDAQRQGTGKALLRHVIAWA-ETHGYRQMIAIVgDSNNQGSLKVHQQVGFTEKGTLKDIGFKHGRWLDTVLLQ 160
Cdd:COG1670    90 EIGYWLAPAYWGKGYATEALRALLDYAfEELGLHRVEAEV-DPDNTASIRVLEKLGFRLEGTLRDALVIDGRYRDHVLYS 168


                  .
gi 2788638439 161 R 161
Cdd:COG1670   169 L 169
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
3-158 1.51e-16

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 72.04  E-value: 1.51e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   3 IVNAEEKHIPAICDIYAhhvihgtASFEtePPDTHEMLARLKKIRNQALPWVvALEEEKVIGYCYLTRYRERYAYRHTLE 82
Cdd:COG3153     1 IRPATPEDAEAIAALLR-------AAFG--PGREAELVDRLREDPAAGLSLV-AEDDGEIVGHVALSPVDIDGEGPALLL 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2788638439  83 DSIYIHPDAQRQGTGKALLRHVIAWAETHGYRqMIAIVGDSNNQGslkVHQQVGFTEKGTLKDIGFKHGRWLDTVL 158
Cdd:COG3153    71 GPLAVDPEYRGQGIGRALMRAALEAARERGAR-AVVLLGDPSLLP---FYERFGFRPAGELGLTLGPDEVFLAKEL 142
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 31-137 3.22e-15

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 67.93  E-value: 3.22e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  31 TEPPDTHEMLARLKKIRNQALPWVVALEEEKVIGYCYLTRYRERYayRHTLEDSIYIHPDAQRQGTGKALLRHVIAWAET 110
Cdd:pfam00583  13 PEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEP--PVGEIEGLAVAPEYRGKGIGTALLQALLEWARE 90

                          90       100
                  ....*....|....*....|....*..
gi 2788638439 111 HGYRQMIAIVgDSNNQGSLKVHQQVGF 137
Cdd:pfam00583  91 RGCERIFLEV-AADNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 1-139 7.73e-15

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 67.39  E-value: 7.73e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIyahhvihgtasfeteppdtHEMLARLKKIRNQALP--WVVALEEEKVIGYCYLTRYRERYAYr 78
Cdd:COG0454     1 MSIRKATPEDINFILLI-------------------EALDAELKAMEGSLAGaeFIAVDDKGEPIGFAGLRRLDDKVLE- 60

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2788638439  79 htLEDsIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDsNNQGSLKVHQQVGFTE 139
Cdd:COG0454    61 --LKR-LYVLPEYRGKGIGKALLEALLEWARERGCTALELDTLD-GNPAAIRFYERLGFKE 117
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 1-118 1.03e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 64.24  E-value: 1.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIhgtasfetEPPDTHemlarlkkirnqalpWVVALEEEKVIGYCYLTRYRERYAYrht 80
Cdd:COG1246     1 MTIRPATPDDVPAILELIRPYAL--------EEEIGE---------------FWVAEEDGEIVGCAALHPLDEDLAE--- 54

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2788638439  81 LEdSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIA 118
Cdd:COG1246    55 LR-SLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFL 91
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 64-163 1.76e-12

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 60.05  E-value: 1.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  64 GYCYLTR-YRERYAYrhtLEDsIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVgDSNNQGSLKVHQQVGFTEKGT 142
Cdd:COG0456     1 GFALLGLvDGGDEAE---IED-LAVDPEYRGRGIGRALLEAALERARERGARRLRLEV-REDNEAAIALYEKLGFEEVGE 75

                          90       100
                  ....*....|....*....|.
gi 2788638439 143 LKDIGfkhgrWLDTVLLQRNL 163
Cdd:COG0456    76 RPNYY-----GDDALVMEKEL 91
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 53-117 3.12e-12

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 58.44  E-value: 3.12e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2788638439  53 WVVALEEEKVIGYCYLTRYRERyayRHTLE-DSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMI 117
Cdd:cd04301     1 FLVAEDDGEIVGFASLSPDGSG---GDTAYiGDLAVLPEYRGKGIGSALLEAAEEEARERGAKRLR 63
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 7-138 3.44e-11

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 57.74  E-value: 3.44e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   7 EEKHIPAICDIYAH-HVIHGTASFETEPPDTHEMLARLKKIRN--QALPWVVALEEEKVIGYCYLTRYRERyayRHTLED 83
Cdd:pfam13302   8 TEEDAEALFELLSDpEVMRYGVPWPLTLEEAREWLARIWAADEaeRGYGWAIELKDTGFIGSIGLYDIDGE---PERAEL 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2788638439  84 SIYIHPDAQRQGTGKALLRHVIAWA-ETHGYRQMIAIVgDSNNQGSLKVHQQVGFT 138
Cdd:pfam13302  85 GYWLGPDYWGKGYATEAVRALLEYAfEELGLPRLVARI-DPENTASRRVLEKLGFK 139
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 54-139 1.38e-10

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 54.77  E-value: 1.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  54 VVALEEEKVIGYCYLTRYRERYayrHTLEDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAivgdSNNQGSLKVHQ 133
Cdd:pfam13508   6 FVAEDDGKIVGFAALLPLDDEG---ALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLEL----ETTNRAAAFYE 78


                  ....*.
gi 2788638439 134 QVGFTE 139
Cdd:pfam13508  79 KLGFEE 84
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
61-149 1.21e-08

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 49.52  E-value: 1.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  61 KVIGYCYLTRYRERYAYrhtlEDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSnNQGSLKVHQQVGFTEK 140
Cdd:COG3393     1 ELVAMAGVRAESPGVAE----ISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDAD-NPAARRLYERLGFRPV 75


                  ....*....
gi 2788638439 141 GTLKDIGFK 149
Cdd:COG3393    76 GEYATVLFR 84
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 44-141 2.06e-07

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 47.27  E-value: 2.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  44 KKIRNQALPWVVALEEEKVIGYCYLtrYRERYAYRhtledsIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDS 123
Cdd:pfam13673  24 ERIDQGEYFFFVAFEGGQIVGVIAL--RDRGHISL------LFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSELTVNAS 95

                          90
                  ....*....|....*...
gi 2788638439 124 NNqgSLKVHQQVGFTEKG 141
Cdd:pfam13673  96 PY--AVPFYEKLGFRATG 111
PRK07757 PRK07757
N-acetyltransferase;
1-118 3.59e-06

N-acetyltransferase;


Pssm-ID: 236088 [Multi-domain]  Cd Length: 152  Bit Score: 44.41  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   1 MKIVNAEEKHIPAICDIYAHHVIHGtasfeteppdthEMLAR-----LKKIRNqalpWVVALEEEKVIGYCYLTRYRERY 75
Cdd:PRK07757    2 MEIRKARLSDVKAIHALINVYAKKG------------LMLPRsldelYENIRD----FYVAEEEGEIVGCCALHILWEDL 65

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2788638439  76 A-YRhtledSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIA 118
Cdd:PRK07757   66 AeIR-----SLAVSEDYRGQGIGRMLVEACLEEARELGVKRVFA 104
rimI PRK09491
ribosomal-protein-alanine N-acetyltransferase; Provisional
 85-139 8.47e-06

ribosomal-protein-alanine N-acetyltransferase; Provisional


Pssm-ID: 181904 [Multi-domain]  Cd Length: 146  Bit Score: 43.38  E-value: 8.47e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2788638439  85 IYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSnNQGSLKVHQQVGFTE 139
Cdd:PRK09491   69 IAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRAS-NAAAIALYESLGFNE 122
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
56-158 1.50e-05

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 42.74  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  56 ALEEEKVIGYCYLTRYRerYAYRHTLEDSIYIHPDAQRqGTGKALLRHVIAWAET-HGYRQMIAIVGdSNNQGSLKVHQQ 134
Cdd:pfam13420  54 VAESDRLIGYATLRQFD--YVKTHKAELSFYVVKNNDE-GINRELINAIIQYARKnQNIENLEACIA-SNNINAIVFLKA 129

                          90       100
                  ....*....|....*....|....
gi 2788638439 135 VGFTEKGTLKDIGFKHGRWLDTVL 158
Cdd:pfam13420 130 IGFEWLGIERNAIKKNGRWIDMMW 153
PRK10140 PRK10140
N-acetyltransferase;
3-161 4.70e-04

N-acetyltransferase;


Pssm-ID: 182263 [Multi-domain]  Cd Length: 162  Bit Score: 38.81  E-value: 4.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439   3 IVNAEEKHIPAICDIYAH-HVIHGTasFETEPPDTHEMLARLKKirNQALPWVVALEEEKVIGYCYLTrYRERYAYRHTL 81
Cdd:PRK10140    6 IRHAETRDYEAIRQIHAQpEVYHNT--LQVPHPSDHMWQERLAD--RPGIKQLVACIDGDVVGHLTID-VQQRPRRSHVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  82 EDSIYIHPDAQRQGTGKALLRHVIAWAETHGYRQMIAIVGDSNNQGSLKVHQQVGFTEKGTLKDIGFKHGRWLDTVLLQR 161
Cdd:PRK10140   81 DFGICVDSRWKNRGVASALMREMIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR 160
COG3981 COG3981
Predicted acetyltransferase [General function prediction only];
53-131 4.21e-03

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443180  Cd Length: 170  Bit Score: 36.04  E-value: 4.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2788638439  53 WVVAlEEEKVIGycyltryreRYAYRHTLEDSIY---------IHPDAQRQGTGKALLRHVIAWAETHGYRQmIAIVGDS 123
Cdd:COG3981    66 WLVD-EDGRIVG---------AINLRHELNEFLLrvgghigygVRPSERGKGYATEMLRLALEEARELGLDR-VLITCDK 134


                  ....*...
gi 2788638439 124 NNQGSLKV 131
Cdd:COG3981   135 DNIASRKV 142
TmcA COG1444
tRNA(Met) C34 N-acetyltransferase TmcA [Translation, ribosomal structure and biogenesis]; tRNA ...
 85-113 7.37e-03

tRNA(Met) C34 N-acetyltransferase TmcA [Translation, ribosomal structure and biogenesis]; tRNA(Met) C34 N-acetyltransferase TmcA is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441053 [Multi-domain]  Cd Length: 703  Bit Score: 35.96  E-value: 7.37e-03
                          10        20
                  ....*....|....*....|....*....
gi 2788638439  85 IYIHPDAQRQGTGKALLRHVIAWAETHGY 113
Cdd:COG1444   491 IAVHPALQRRGLGSRLLAEIREEAKEEGL 519
Acetyltransf_6 pfam13480
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 37-114 8.89e-03

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions.


Pssm-ID: 433244 [Multi-domain]  Cd Length: 143  Bit Score: 34.94  E-value: 8.89e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2788638439  37 HEMLARLKKIRNQALPWVVALEEEkVIGYCYLTRYRERYAYRHTledsiYIHPDAQRQGTGKALLRHVIAWAETHGYR 114
Cdd:pfam13480  59 LRDLLAALAARGALRLYVLRLDGR-PVAALLGLRSGDRLYYWFG-----GYDPEYARLSPGLLLLWELIEHAAEEGLR 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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