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Conserved domains on  [gi|2790478622|ref|WP_371175902|]
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DUF5801 repeats-in-toxin domain-containing protein, partial [Aeromonas sp. S19(2024)]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
T1SS_rpt_143 super family cl42883
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 7-126 5.70e-17

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


The actual alignment was detected with superfamily member TIGR03660:

Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 76.17  E-value: 5.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622   7 GDLAITAGADPLVNIAFDASQPGLQGLTSGGLPVVITISGNS-----ISGAVNGQNVFTLTLDQNGHYVFTLNQPLDQ-- 79
Cdd:TIGR03660   1 GQFTVTQGADGVVSYQLDDSTNPVAGLTSGGQAVTLSETSNAdgnftYTATAGGNPVFTLTLNADGSYEFTLEGPLDHaa 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2790478622  80 GSADSLLKAGFTLTDSDGDTVSSTLSVAIGDGAnPVISAVTGTEMTE 126
Cdd:TIGR03660  81 GSDELTLNFPIIATDFDGDTSSITLPVTIVDDV-PTITDVDALTVDE 126
T1SS_rpt_143 super family cl42883
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 140-283 3.88e-06

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


The actual alignment was detected with superfamily member TIGR03660:

Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 45.74  E-value: 3.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622 140 FTVSHGADALDTsslkFDIAAIQQSLDGkYSSHGSPVTFTLDANGELVGT---SADGREVLRAELSlveNNGNWSVTakv 216
Cdd:TIGR03660   3 FTVTQGADGVVS----YQLDDSTNPVAG-LTSGGQAVTLSETSNADGNFTytaTAGGNPVFTLTLN---ADGSYEFT--- 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2790478622 217 tLGAELDH-QGSESLDLPLTVTLTDKDGDRVSTDLPLTIKDgHAPHFVGGSGVSLDERGLDGSNTLTG 283
Cdd:TIGR03660  72 -LEGPLDHaAGSDELTLNFPIIATDFDGDTSSITLPVTIVD-DVPTITDVDALTVDEDDLPGGSDGSK 137
 
Name Accession Description Interval E-value
T1SS_rpt_143 TIGR03660
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 7-126 5.70e-17

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 76.17  E-value: 5.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622   7 GDLAITAGADPLVNIAFDASQPGLQGLTSGGLPVVITISGNS-----ISGAVNGQNVFTLTLDQNGHYVFTLNQPLDQ-- 79
Cdd:TIGR03660   1 GQFTVTQGADGVVSYQLDDSTNPVAGLTSGGQAVTLSETSNAdgnftYTATAGGNPVFTLTLNADGSYEFTLEGPLDHaa 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2790478622  80 GSADSLLKAGFTLTDSDGDTVSSTLSVAIGDGAnPVISAVTGTEMTE 126
Cdd:TIGR03660  81 GSDELTLNFPIIATDFDGDTSSITLPVTIVDDV-PTITDVDALTVDE 126
T1SS_rpt_143 TIGR03660
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 140-283 3.88e-06

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 45.74  E-value: 3.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622 140 FTVSHGADALDTsslkFDIAAIQQSLDGkYSSHGSPVTFTLDANGELVGT---SADGREVLRAELSlveNNGNWSVTakv 216
Cdd:TIGR03660   3 FTVTQGADGVVS----YQLDDSTNPVAG-LTSGGQAVTLSETSNADGNFTytaTAGGNPVFTLTLN---ADGSYEFT--- 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2790478622 217 tLGAELDH-QGSESLDLPLTVTLTDKDGDRVSTDLPLTIKDgHAPHFVGGSGVSLDERGLDGSNTLTG 283
Cdd:TIGR03660  72 -LEGPLDHaAGSDELTLNFPIIATDFDGDTSSITLPVTIVD-DVPTITDVDALTVDEDDLPGGSDGSK 137
 
Name Accession Description Interval E-value
T1SS_rpt_143 TIGR03660
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 7-126 5.70e-17

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 76.17  E-value: 5.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622   7 GDLAITAGADPLVNIAFDASQPGLQGLTSGGLPVVITISGNS-----ISGAVNGQNVFTLTLDQNGHYVFTLNQPLDQ-- 79
Cdd:TIGR03660   1 GQFTVTQGADGVVSYQLDDSTNPVAGLTSGGQAVTLSETSNAdgnftYTATAGGNPVFTLTLNADGSYEFTLEGPLDHaa 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2790478622  80 GSADSLLKAGFTLTDSDGDTVSSTLSVAIGDGAnPVISAVTGTEMTE 126
Cdd:TIGR03660  81 GSDELTLNFPIIATDFDGDTSSITLPVTIVDDV-PTITDVDALTVDE 126
T1SS_rpt_143 TIGR03660
T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur ...
 140-283 3.88e-06

T1SS-143 repeat domain; This model represents a domain of about 143 amino acids that may occur singly or in up to 23 tandem repeats in very large proteins in the genus Vibrio, and in related species such as Legionella pneumophila, Photobacterium profundum, Rhodopseudomonas palustris, Shewanella pealeana, and Aeromonas hydrophila. Proteins with these domains represent a subset of a broader set of proteins with a particular signal for type 1 secretion, consisting of several glycine-rich repeats modeled by pfam00353, followed by a C-terminal domain modeled by TIGR03661. Proteins with this domain tend to share several properties with the RtxA (Repeats in Toxin) protein of Vibrio cholerae, including a large size often containing tandemly repeated domains and a C-terminal signal for type 1 secretion. [Cellular processes, Pathogenesis]


Pssm-ID: 132699 [Multi-domain]  Cd Length: 137  Bit Score: 45.74  E-value: 3.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790478622 140 FTVSHGADALDTsslkFDIAAIQQSLDGkYSSHGSPVTFTLDANGELVGT---SADGREVLRAELSlveNNGNWSVTakv 216
Cdd:TIGR03660   3 FTVTQGADGVVS----YQLDDSTNPVAG-LTSGGQAVTLSETSNADGNFTytaTAGGNPVFTLTLN---ADGSYEFT--- 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2790478622 217 tLGAELDH-QGSESLDLPLTVTLTDKDGDRVSTDLPLTIKDgHAPHFVGGSGVSLDERGLDGSNTLTG 283
Cdd:TIGR03660  72 -LEGPLDHaAGSDELTLNFPIIATDFDGDTSSITLPVTIVD-DVPTITDVDALTVDEDDLPGGSDGSK 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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