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Conserved domains on  [gi|2790649057|ref|WP_371283079|]
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hypothetical protein [Dokdonella sp.]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11475669)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TolBN COG5616
TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];
157-280 3.10e-57

TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];


:

Pssm-ID: 444347  Cd Length: 135  Bit Score: 188.94  E-value: 3.10e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 157 SIAVLPFVNMSADKDNEFFSDGISEELLNVLVRVDGLQVASRTSSFAYKGKEMSSQAIARELKVGHLLEGSVRKSGDRLR 236
Cdd:COG5616    12 SIAVLPFENLSGDPEQEYFADGLTEELITALSRLRGLRVIARTSSFAFKGRAVDLREIARELGVRYVLEGSVRRSGDRVR 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2790649057 237 ITAQLIDAVNDRHLWSETYDRDLTDIFAIQSEIATAIATALSTE 280
Cdd:COG5616    92 VTAQLIDAATGRHLWSERYDRDLDDLFALQDEIARAIAAALAPR 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
309-472 2.62e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 309 ELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMPWAALSLAEM 388
Cdd:COG0457    16 LAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAY--------LRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 389 KNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMA 468
Cdd:COG0457    88 ALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165


                  ....
gi 2790649057 469 AFEQ 472
Cdd:COG0457   166 LLEK 169
UPF0182 super family cl42153
Uncharacterized protein family (UPF0182); This family contains uncharacterized integral ...
 36-113 6.28e-03

Uncharacterized protein family (UPF0182); This family contains uncharacterized integral membrane proteins.


The actual alignment was detected with superfamily member PRK00068:

Pssm-ID: 477987  Cd Length: 970  Bit Score: 39.59  E-value: 6.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057  36 IFDTPA--WVLKALVVLLAIGFIPALVFSWLFELTPDGIKRdadVSVTQSIAAKTGQRMdrLIFAGVLALIAVVAadrYW 113
Cdd:PRK00068  160 AFKLPFyrSLLSYLLVLLILAFIITLIAHYILGGIRKGIRL---AGRKGGISRFARKQL--AVLAGLLMLLKAVG---YW 231
 
Name Accession Description Interval E-value
TolBN COG5616
TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];
157-280 3.10e-57

TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];


Pssm-ID: 444347  Cd Length: 135  Bit Score: 188.94  E-value: 3.10e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 157 SIAVLPFVNMSADKDNEFFSDGISEELLNVLVRVDGLQVASRTSSFAYKGKEMSSQAIARELKVGHLLEGSVRKSGDRLR 236
Cdd:COG5616    12 SIAVLPFENLSGDPEQEYFADGLTEELITALSRLRGLRVIARTSSFAFKGRAVDLREIARELGVRYVLEGSVRRSGDRVR 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2790649057 237 ITAQLIDAVNDRHLWSETYDRDLTDIFAIQSEIATAIATALSTE 280
Cdd:COG5616    92 VTAQLIDAATGRHLWSERYDRDLDDLFALQDEIARAIAAALAPR 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
309-472 2.62e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 309 ELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMPWAALSLAEM 388
Cdd:COG0457    16 LAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAY--------LRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 389 KNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMA 468
Cdd:COG0457    88 ALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165


                  ....
gi 2790649057 469 AFEQ 472
Cdd:COG0457   166 LLEK 169
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 280-468 1.14e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 280 ELGDGAKSVV-LVKADTENLSAyelylKARELFIARSDLreSIRLYERVVEMDPNFARGWEGLAAVYCIVQGWGirdrdY 358
Cdd:TIGR02917  68 ALGDYAAAEKeLRKALSLGYPK-----NQVLPLLARAYL--LQGKFQQVLDELPGKTLLDDEGAAELLALRGLA-----Y 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 359 LALVE-ATAKRALELDSTLS--MPWAALSLAEMKNRPVNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALAD 435
Cdd:TIGR02917 136 LGLGQlELAQKSYEQALAIDprSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAA 215

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2790649057 436 QRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMA 468
Cdd:TIGR02917 216 YRKAIALRPNNIAVLLALATILIEAGEFEEAEK 248
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 394-475 1.51e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.47  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 394 NWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQG 473
Cdd:PLN03088   17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALEKG 96


                  ..
gi 2790649057 474 VA 475
Cdd:PLN03088   97 AS 98
PRK00068 PRK00068
hypothetical protein; Validated
 36-113 6.28e-03

hypothetical protein; Validated


Pssm-ID: 234609  Cd Length: 970  Bit Score: 39.59  E-value: 6.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057  36 IFDTPA--WVLKALVVLLAIGFIPALVFSWLFELTPDGIKRdadVSVTQSIAAKTGQRMdrLIFAGVLALIAVVAadrYW 113
Cdd:PRK00068  160 AFKLPFyrSLLSYLLVLLILAFIITLIAHYILGGIRKGIRL---AGRKGGISRFARKQL--AVLAGLLMLLKAVG---YW 231
 
Name Accession Description Interval E-value
TolBN COG5616
TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];
157-280 3.10e-57

TolB amino-terminal domain (function unknown) [Signal transduction mechanisms];


Pssm-ID: 444347  Cd Length: 135  Bit Score: 188.94  E-value: 3.10e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 157 SIAVLPFVNMSADKDNEFFSDGISEELLNVLVRVDGLQVASRTSSFAYKGKEMSSQAIARELKVGHLLEGSVRKSGDRLR 236
Cdd:COG5616    12 SIAVLPFENLSGDPEQEYFADGLTEELITALSRLRGLRVIARTSSFAFKGRAVDLREIARELGVRYVLEGSVRRSGDRVR 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2790649057 237 ITAQLIDAVNDRHLWSETYDRDLTDIFAIQSEIATAIATALSTE 280
Cdd:COG5616    92 VTAQLIDAATGRHLWSERYDRDLDDLFALQDEIARAIAAALAPR 135
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
309-472 2.62e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 309 ELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMPWAALSLAEM 388
Cdd:COG0457    16 LAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAY--------LRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 389 KNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMA 468
Cdd:COG0457    88 ALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165


                  ....
gi 2790649057 469 AFEQ 472
Cdd:COG0457   166 LLEK 169
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
328-475 4.92e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.04  E-value: 4.92e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 328 VEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIE 407
Cdd:COG0457     1 LELDPDDAEAYNNLGLAY--------RRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLG--RYEEALADYEQALE 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2790649057 408 ANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQGVA 475
Cdd:COG0457    71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALE 138
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 293-456 7.97e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.56  E-value: 7.97e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 293 ADTENLSAYELYLKARELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALEL 372
Cdd:COG3914    70 AAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLL--------LALGRLEEALAALRRALAL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 373 DSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDP----AYQN 448
Cdd:COG3914   142 NPDFAEAYLNLGEALRRLG--RLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPdnadAHSN 219


                  ....*...
gi 2790649057 449 CLRWVSQS 456
Cdd:COG3914   220 LLFALRQA 227
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-495 2.06e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 2.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 290 LVKADTENLsayELYLKARELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRA 369
Cdd:COG2956    34 ALELDPETV---EAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY--------LKAGLLDRAEELLEKL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 370 LELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNC 449
Cdd:COG2956   103 LELDPDDAEALRLLAEIYEQEG--DWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2790649057 450 LRWVSQSLVSEGKQDEAMAAFEQgvangfVENRASAFVPVLIQRGD 495
Cdd:COG2956   181 LLLLAELYLEQGDYEEAIAALER------ALEQDPDYLPALPRLAE 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-476 5.50e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 5.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 290 LVKADTENLSAY----ELYLKARelfiarsDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgIRDRDYLALVEaT 365
Cdd:COG2956    68 LLERDPDRAEALlelaQDYLKAG-------LLDRAEELLEKLLELDPDDAEALRLLAEIY-------EQEGDWEKAIE-V 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 366 AKRALELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPA 445
Cdd:COG2956   133 LERLLKLGPENAHAYCELAELYLEQG--DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2790649057 446 YQNCLRWVSQSLVSEGKQDEAMAAFEQGVAN 476
Cdd:COG2956   211 YLPALPRLAELYEKLGDPEEALELLRKALEL 241
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 290-472 9.35e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.82  E-value: 9.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 290 LVKADTENLSAYELYLkarELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRA 369
Cdd:COG2956   102 LLELDPDDAEALRLLA---EIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELY--------LEQGDYDEAIEALEKA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 370 LELDStlSMPWAALSLAEMKNRPVNWEKSIELANRAIEANPNNTTALLwrSVSWVY--LGYFDKALADQRRCLELDPAYQ 447
Cdd:COG2956   171 LKLDP--DCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP--RLAELYekLGDPEEALELLRKALELDPSDD 246

                         170       180
                  ....*....|....*....|....*
gi 2790649057 448 NcLRWVSQSLVSEGKQDEAMAAFEQ 472
Cdd:COG2956   247 L-LLALADLLERKEGLEAALALLER 270
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 300-446 1.52e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 1.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 300 AYELYLKARELFIARsDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgIRDRDYLALVEAtAKRALELDSTLSMP 379
Cdd:COG4783     4 AEALYALAQALLLAG-DYDEAEALLEKALELDPDNPEAFALLGEIL-------LQLGDLDEAIVL-LHEALELDPDEPEA 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2790649057 380 WAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAY 446
Cdd:COG4783    75 RLNLGLALLKAG--DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-445 1.57e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.17  E-value: 1.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 319 ESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgIRDRDYLALVEAtAKRALELDSTlsMPWAALSLAEMKNRPVNWEKS 398
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAY-------LRLGRYDEALAA-YEKALRLDPD--NADALLDLAEALLAAGDTEEA 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2790649057 399 IELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPA 445
Cdd:COG4235    71 EELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPA 117
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 300-538 3.09e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.20  E-value: 3.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 300 AYELYLKAReLFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMP 379
Cdd:COG2956     8 ALGWYFKGL-NYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLY--------RRRGEYDRAIRIHQKLLERDPDRAEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 380 WAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVS 459
Cdd:COG2956    79 LLELAQDYLKAG--LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLE 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2790649057 460 EGKQDEAMAAFEQGVAngfvenRASAFVPVLIQRGDllsarlLLRSLGSPSELTEIFVQALQEpggvHPDARAIMDRLA 538
Cdd:COG2956   157 QGDYDEAIEALEKALK------LDPDCARALLLLAE------LYLEQGDYEEAIAALERALEQ----DPDYLPALPRLA 219
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 380-475 2.46e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 2.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 380 WAALSLAEMKNRPVNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVS 459
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90
                  ....*....|....*.
gi 2790649057 460 EGKQDEAMAAFEQGVA 475
Cdd:COG4783    85 AGDYDEALALLEKALK 100
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 335-476 5.82e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 52.66  E-value: 5.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 335 ARGWEGLAAVYCIVQGWGIRDRDYLALVEATAKRALELDSTLSMPWAALSLAEMKNrpvnWEKSIELANRAIEANPNNTT 414
Cdd:COG5010    14 LLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGD----FEESLALLEQALQLDPNNPE 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2790649057 415 ALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQGVAN 476
Cdd:COG5010    90 LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
394-476 1.95e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 1.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 394 NWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALAdQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQG 473
Cdd:COG3063     7 DLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERA 85


                  ...
gi 2790649057 474 VAN 476
Cdd:COG3063    86 LEL 88
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
368-472 3.69e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.45  E-value: 3.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 368 RALELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDP--A 445
Cdd:COG4785    98 QALELDPDLAEAYNNRGLAYLLLG--DYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPndP 175

                          90       100
                  ....*....|....*....|....*..
gi 2790649057 446 YQNCLRWVSQslvSEGKQDEAMAAFEQ 472
Cdd:COG4785   176 ERALWLYLAE---RKLDPEKALALLLE 199
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
307-472 1.44e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.53  E-value: 1.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 307 ARELFIARSDLRESIRLYERVVEMDPNFARgweglAAVYCIVQGWGIRDRDYLALVEATAKRALE-LDSTLSMPWAALSL 385
Cdd:COG4785     2 YALALALLLALALAAAAASKAAILLAALLF-----AAVLALAIALADLALALAAAALAAAALAAErIDRALALPDLAQLY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 386 AE--MKNRPV-NWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGK 462
Cdd:COG4785    77 YErgVAYDSLgDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGR 156

                         170
                  ....*....|
gi 2790649057 463 QDEAMAAFEQ 472
Cdd:COG4785   157 YELAIADLEK 166
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 364-472 4.15e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 4.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 364 ATAKRALELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELD 443
Cdd:COG4235     4 ARLRQALAANPNDAEGWLLLGRAYLRLG--RYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100
                  ....*....|....*....|....*....
gi 2790649057 444 PAYQNCLRWVSQSLVSEGKQDEAMAAFEQ 472
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAWQK 110
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
363-445 8.49e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 8.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 363 EATAKRALELDSTLSMPWAALSLAEMKNRpvNWEKSIELaNRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLEL 442
Cdd:COG3063    12 EEYYEKALELDPDNADALNNLGLLLLEQG--RYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                  ...
gi 2790649057 443 DPA 445
Cdd:COG3063    89 DPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 280-468 1.14e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 280 ELGDGAKSVV-LVKADTENLSAyelylKARELFIARSDLreSIRLYERVVEMDPNFARGWEGLAAVYCIVQGWGirdrdY 358
Cdd:TIGR02917  68 ALGDYAAAEKeLRKALSLGYPK-----NQVLPLLARAYL--LQGKFQQVLDELPGKTLLDDEGAAELLALRGLA-----Y 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 359 LALVE-ATAKRALELDSTLS--MPWAALSLAEMKNRPVNWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALAD 435
Cdd:TIGR02917 136 LGLGQlELAQKSYEQALAIDprSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAA 215

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2790649057 436 QRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMA 468
Cdd:TIGR02917 216 YRKAIALRPNNIAVLLALATILIEAGEFEEAEK 248
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 255-410 1.22e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 1.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 255 YDRDLTDIFAIQSEIATAIATALSTELGDGAKSVVLVKADTENLSAYELYLKARELFIARSDLRESIRLYERVVEMDPNF 334
Cdd:COG5010     8 DRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2790649057 335 ARGWEGLAAVYcivqgwgIRDRDYlALVEATAKRALELDSTLSMPWAALSLAEMKNRpvNWEKSIELANRAIEANP 410
Cdd:COG5010    88 PELYYNLALLY-------SRSGDK-DEAKEYYEKALALSPDNPNAYSNLAALLLSLG--QDDEAKAALQRALGTSP 153
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 394-475 1.51e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 47.47  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 394 NWEKSIELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQG 473
Cdd:PLN03088   17 DFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLEEYQTAKAALEKG 96


                  ..
gi 2790649057 474 VA 475
Cdd:PLN03088   97 AS 98
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 399-475 2.54e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 2.54e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2790649057 399 IELANRAIEANPNNTTALLWRSVSWVYLGYFDKALADQRRCLELDPAYQNCLRWVSQSLVSEGKQDEAMAAFEQGVA 475
Cdd:COG4235     3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA 79
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
310-411 4.97e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 4.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 310 LFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYCivqgwgiRDRDYlalVEATA-KRALELDStlSMPWAALSLAEM 388
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLL-------EQGRY---DEAIAlEKALKLDP--NNAEALLNLAEL 68

                          90       100
                  ....*....|....*....|...
gi 2790649057 389 KNRPVNWEKSIELANRAIEANPN 411
Cdd:COG3063    69 LLELGDYDEALAYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 257-443 7.45e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 7.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 257 RDLTDIFAIQSEIATAIATALstelgdgaksvvlvKADTENLSAYELYLKARELFIARSDLRESIRLYERVVEMDPNFAR 336
Cdd:COG2956   114 RLLAEIYEQEGDWEKAIEVLE--------------RLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 337 GWEGLAAVYcivqgwgIRDRDYlALVEATAKRALELDSTLSMpwAALSLAEMKNRPVNWEKSIELANRAIEANPNNtTAL 416
Cdd:COG2956   180 ALLLLAELY-------LEQGDY-EEAIAALERALEQDPDYLP--ALPRLAELYEKLGDPEEALELLRKALELDPSD-DLL 248

                         170       180
                  ....*....|....*....|....*..
gi 2790649057 417 LWRSVSWVYLGYFDKALADQRRCLELD 443
Cdd:COG2956   249 LALADLLERKEGLEAALALLERQLRRH 275
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 394-472 4.51e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 4.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 394 NWEKSIELANRAIEANPNNT---TALLWRSVSWVYLGYFDKALADQRRCLELDPA---YQNCLRWVSQSLVSEGKQDEAM 467
Cdd:COG1729     8 DYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKAR 87


                  ....*
gi 2790649057 468 AAFEQ 472
Cdd:COG1729    88 ATLEE 92
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 302-416 5.31e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.98  E-value: 5.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 302 ELYLKARELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwgiRDRDYLALVEATAKRALELDSTLSMPWA 381
Cdd:COG3914   147 EAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNAL--------QDLGRLEEAIAAYRRALELDPDNADAHS 218

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2790649057 382 ALSLAEMKNRPVNWEKSIELANRAIEANPNNTTAL 416
Cdd:COG3914   219 NLLFALRQACDWEVYDRFEELLAALARGPSELSPF 253
PRK00068 PRK00068
hypothetical protein; Validated
 36-113 6.28e-03

hypothetical protein; Validated


Pssm-ID: 234609  Cd Length: 970  Bit Score: 39.59  E-value: 6.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057  36 IFDTPA--WVLKALVVLLAIGFIPALVFSWLFELTPDGIKRdadVSVTQSIAAKTGQRMdrLIFAGVLALIAVVAadrYW 113
Cdd:PRK00068  160 AFKLPFyrSLLSYLLVLLILAFIITLIAHYILGGIRKGIRL---AGRKGGISRFARKQL--AVLAGLLMLLKAVG---YW 231
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 309-414 9.19e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 9.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2790649057 309 ELFIARSDLRESIRLYERVVEMDPNFARGWEGLAAVYcivqgwGIRDRdylALVEATAKRALEL--DSTLSMPWAALSLA 386
Cdd:TIGR02917 778 ELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLY------LELKD---PRALEYAERALKLapNIPAILDTLGWLLV 848

                          90       100
                  ....*....|....*....|....*...
gi 2790649057 387 EMKNRpvnwEKSIELANRAIEANPNNTT 414
Cdd:TIGR02917 849 EKGEA----DRALPLLRKAVNIAPEAAA 872
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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