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Conserved domains on  [gi|2791320920|ref|WP_371352430|]
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IS3 family transposase [Pseudoalteromonas sp. 68 DY56-GL68]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-368 2.41e-159

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 451.63  E-value: 2.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920   9 EFKDEAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKK----------TKVPAKKSAEQEEIRKLRAELKRVTEERNIFKG 78
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKyrgggeaadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  79 SRRVLCKRVKerYAFIKSRLEVYRVKAMCQALNVHRSGFYAWLKQPLSKREQDNRRLLERIKAGYVESGGVYGSPRITHE 158
Cdd:NF033516   81 ARKLLRPAVK--YALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 159 LRRQGETCGENRVARLMKQAKLKANIGYKRRYF--KSTVPALIADNHLQQQFVVSEPDTAWVADITYIKTYEGWLYLAVV 236
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPYttDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 237 LDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIVHSDQGSQYASCDYREFLTANNLVPSMSRRGHCLDNAVAE 316
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2791320920 317 SFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYE 368
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-368 2.41e-159

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 451.63  E-value: 2.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920   9 EFKDEAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKK----------TKVPAKKSAEQEEIRKLRAELKRVTEERNIFKG 78
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKyrgggeaadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  79 SRRVLCKRVKerYAFIKSRLEVYRVKAMCQALNVHRSGFYAWLKQPLSKREQDNRRLLERIKAGYVESGGVYGSPRITHE 158
Cdd:NF033516   81 ARKLLRPAVK--YALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 159 LRRQGETCGENRVARLMKQAKLKANIGYKRRYF--KSTVPALIADNHLQQQFVVSEPDTAWVADITYIKTYEGWLYLAVV 236
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPYttDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 237 LDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIVHSDQGSQYASCDYREFLTANNLVPSMSRRGHCLDNAVAE 316
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2791320920 317 SFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYE 368
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
54-372 2.70e-103

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 307.08  E-value: 2.70e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  54 AEQEEIRKLRAELKRVTEERNIFKGSRRVLCKRVKERYAFIKSRLEVYRVKAMCQALNVHRSgfyawlkqplsKREQDNR 133
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRS-----------YRADEDA 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 134 RLLERIKAGYVESGgVYGSPRITHELRRQGETCGENRVARLMKQAKLKANIGYKRRY-FKSTVPALIADNHLqqqFVVSE 212
Cdd:COG2801    72 ELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYtTYSGHGGPIAPNLL---FTATA 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 213 PDTAWVADITYIKTYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIVHSDQGSQYASCDYRE 292
Cdd:COG2801   148 PNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQE 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 293 FLTANNLVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYEKQYL 372
Cdd:COG2801   228 LLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
110-375 3.37e-82

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 252.09  E-value: 3.37e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 110 LNVHRSGFYAWLKQPL--SKREQDNRR---LLERIKAGYVESGGVYGSPRITHELRRQGETCGENRVARLMKQAKLKANI 184
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHhpDKRRARAQHddwLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 185 GYKRRYFKSTVPALIADNHLQQQFVVSEPDTAWVADITYIKTYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLM 264
Cdd:PHA02517   81 RGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 265 AVWRRNPKHEVIVHSDQGSQYASCDYREFLTANNLVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFD 344
Cdd:PHA02517  161 ALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLE 240
                         250       260       270
                  ....*....|....*....|....*....|.
gi 2791320920 345 YIEmFYNRKRLHSHLGHVSPEEYEKQYLTGS 375
Cdd:PHA02517  241 WVA-WYNNRRLHERLGYTPPAEAEKAYYASI 270
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
213-309 3.47e-29

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 108.56  E-value: 3.47e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 213 PDTAWVADITYIK--TYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIvHSDQGSQYASCDY 290
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLII-HSDNGSEYTSKAF 79
                          90
                  ....*....|....*....
gi 2791320920 291 REFLTANNLVPSMSRRGHC 309
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
13-364 2.34e-11

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 63.76  E-value: 2.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  13 EAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKKTKvpakksAEQEEirklrAELKRvteernifkgSRRvlckrvkerya 92
Cdd:NF033577    4 ELVRLVLEDGWSVREAARRFGISRKTVYKWLKRYR------AGGEE-----GLIDR----------SRR----------- 51
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  93 fiksrlevyrvkamcqalnvhrsgfyawlkqPLSKREQDNRRLLERIKAGYVESGgvYGSPRITHELRRQGETCGENRVA 172
Cdd:NF033577   52 -------------------------------PHRSPRRTSPETEARILALRRELR--LGPRRIAYELERQGPGVSRSTVH 98
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 173 RLMKQ------AKLKANIGYKRRYFKStvpaliADNHLqqqfvvsepdtaWVADITYIKT--YEGWLYLAVVLDLFSRKI 244
Cdd:NF033577   99 RILRRhglsrlRALDRKTGKVKRYERA------HPGEL------------WHIDIKKLGRipDVGRLYLHTAIDDHSRFA 160
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 245 IGwSMQPNMSKDIVIKALLMAVWRRN-PKHEVIvhSDQGSQYAS--CDYREFLTANNLVPSMSRRGHCLDNAVAESFFHS 321
Cdd:NF033577  161 YA-ELYPDETAETAADFLRRAFAEHGiPIRRVL--TDNGSEFRSraHGFELALAELGIEHRRTRPYHPQTNGKVERFHRT 237
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2791320920 322 LKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSP 364
Cdd:NF033577  238 LKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTP 279
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-368 2.41e-159

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 451.63  E-value: 2.41e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920   9 EFKDEAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKK----------TKVPAKKSAEQEEIRKLRAELKRVTEERNIFKG 78
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKyrgggeaadaGRLKELLTPEEEENRRLKRELAELRLENEILKK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  79 SRRVLCKRVKerYAFIKSRLEVYRVKAMCQALNVHRSGFYAWLKQPLSKREQDNRRLLERIKAGYVESGGVYGSPRITHE 158
Cdd:NF033516   81 ARKLLRPAVK--YALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITAL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 159 LRRQGETCGENRVARLMKQAKLKANIGYKRRYF--KSTVPALIADNHLQQQFVVSEPDTAWVADITYIKTYEGWLYLAVV 236
Cdd:NF033516  159 LRREGIRVNHKRVYRLMRELGLLARRRRKRRPYttDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEGWLYLAVV 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 237 LDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIVHSDQGSQYASCDYREFLTANNLVPSMSRRGHCLDNAVAE 316
Cdd:NF033516  239 LDLFSREIVGWSVSTSMSAELVLDALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGNCWDNAVAE 318
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2791320920 317 SFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYE 368
Cdd:NF033516  319 SFFGTLKRECLYRRRFRTLEEARQAIEEYIE-FYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
54-372 2.70e-103

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 307.08  E-value: 2.70e-103
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  54 AEQEEIRKLRAELKRVTEERNIFKGSRRVLCKRVKERYAFIKSRLEVYRVKAMCQALNVHRSgfyawlkqplsKREQDNR 133
Cdd:COG2801     3 AEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRS-----------YRADEDA 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 134 RLLERIKAGYVESGgVYGSPRITHELRRQGETCGENRVARLMKQAKLKANIGYKRRY-FKSTVPALIADNHLqqqFVVSE 212
Cdd:COG2801    72 ELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYtTYSGHGGPIAPNLL---FTATA 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 213 PDTAWVADITYIKTYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIVHSDQGSQYASCDYRE 292
Cdd:COG2801   148 PNQVWVTDITYIPTAEGWLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPLILHSDNGSQYTSKAYQE 227
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 293 FLTANNLVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYEKQYL 372
Cdd:COG2801   228 LLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYRRRFESLEEAREAIEEYIE-FYNHERPHSSLGYLTPAEYEKQLA 306
PHA02517 PHA02517
putative transposase OrfB; Reviewed
110-375 3.37e-82

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 252.09  E-value: 3.37e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 110 LNVHRSGFYAWLKQPL--SKREQDNRR---LLERIKAGYVESGGVYGSPRITHELRRQGETCGENRVARLMKQAKLKANI 184
Cdd:PHA02517    1 LGIAPSTYYRCQQQRHhpDKRRARAQHddwLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 185 GYKRRYFKSTVPALIADNHLQQQFVVSEPDTAWVADITYIKTYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLM 264
Cdd:PHA02517   81 RGKKVRTTISRKAVAAPDRVNRQFVATRPNQLWVADFTYVSTWQGWVYVAFIIDVFARRIVGWRVSSSMDTDFVLDALEQ 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 265 AVWRRNPKHEVIVHSDQGSQYASCDYREFLTANNLVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFD 344
Cdd:PHA02517  161 ALWARGRPGGLIHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLE 240
                         250       260       270
                  ....*....|....*....|....*....|.
gi 2791320920 345 YIEmFYNRKRLHSHLGHVSPEEYEKQYLTGS 375
Cdd:PHA02517  241 WVA-WYNNRRLHERLGYTPPAEAEKAYYASI 270
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
213-309 3.47e-29

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 108.56  E-value: 3.47e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 213 PDTAWVADITYIK--TYEGWLYLAVVLDLFSRKIIGWSMQPNMSKDIVIKALLMAVWRRNPKHEVIvHSDQGSQYASCDY 290
Cdd:pfam00665   1 PNQLWQGDFTYIRipGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLDALERAIAFRGGVPLII-HSDNGSEYTSKAF 79
                          90
                  ....*....|....*....
gi 2791320920 291 REFLTANNLVPSMSRRGHC 309
Cdd:pfam00665  80 REFLKDLGIKPSFSRPGNP 98
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
5-83 1.64e-19

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 82.28  E-value: 1.64e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920   5 KYPQEFKDEAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKK--------TKVPAKKSAEQEEIRKLRAELKRVTEERNIF 76
Cdd:COG2963     7 RYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQyregglggFPGDGRTTPEQAEIRRLRKELRRLEMENDIL 86

                  ....*..
gi 2791320920  77 KGSRRVL 83
Cdd:COG2963    87 KKAAALL 93
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
130-188 1.60e-12

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 61.82  E-value: 1.60e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 130 QDNRRLLERIKAGYVESGGVYGSPRITHELRRQGE-TCGENRVARLMKQAKLKANIGYKR 188
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARRRRKR 60
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
5-67 1.47e-11

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 59.67  E-value: 1.47e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920   5 KYPQEFKDEAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKK-----TKVPAKK--SAEQEEIRKLRAELK 67
Cdd:pfam01527   6 RFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQyeggmGASPARPrlTALEEENRRLKRELA 75
transpos_IS481 NF033577
IS481 family transposase; null
13-364 2.34e-11

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 63.76  E-value: 2.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  13 EAVRQVVDKGYSVPDVAKRLGISDKSLYYWVKKTKvpakksAEQEEirklrAELKRvteernifkgSRRvlckrvkerya 92
Cdd:NF033577    4 ELVRLVLEDGWSVREAARRFGISRKTVYKWLKRYR------AGGEE-----GLIDR----------SRR----------- 51
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920  93 fiksrlevyrvkamcqalnvhrsgfyawlkqPLSKREQDNRRLLERIKAGYVESGgvYGSPRITHELRRQGETCGENRVA 172
Cdd:NF033577   52 -------------------------------PHRSPRRTSPETEARILALRRELR--LGPRRIAYELERQGPGVSRSTVH 98
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 173 RLMKQ------AKLKANIGYKRRYFKStvpaliADNHLqqqfvvsepdtaWVADITYIKT--YEGWLYLAVVLDLFSRKI 244
Cdd:NF033577   99 RILRRhglsrlRALDRKTGKVKRYERA------HPGEL------------WHIDIKKLGRipDVGRLYLHTAIDDHSRFA 160
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 245 IGwSMQPNMSKDIVIKALLMAVWRRN-PKHEVIvhSDQGSQYAS--CDYREFLTANNLVPSMSRRGHCLDNAVAESFFHS 321
Cdd:NF033577  161 YA-ELYPDETAETAADFLRRAFAEHGiPIRRVL--TDNGSEFRSraHGFELALAELGIEHRRTRPYHPQTNGKVERFHRT 237
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2791320920 322 LKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSP 364
Cdd:NF033577  238 LKDEFAYARPYESLAELQAALDEWLH-HYNHHRPHSALGGKTP 279
rve_2 pfam13333
Integrase core domain;
316-372 9.71e-11

Integrase core domain;


Pssm-ID: 372570 [Multi-domain]  Cd Length: 52  Bit Score: 56.50  E-value: 9.71e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2791320920 316 ESFFHSLKTERVKRKVYETRNDARADLFDYIEMfYNRKRLHshlgHVSPEEYEKQYL 372
Cdd:pfam13333   1 ESFFGSLKTEMVYGEHFKTLEELELAIFDYIEW-YNNKRLK----GLSPVQYRNQSL 52
rve_3 pfam13683
Integrase core domain;
301-364 2.66e-10

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 55.69  E-value: 2.66e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2791320920 301 PSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFDYIEMfYNRKRLHSHLGHVSP 364
Cdd:pfam13683   5 ISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWRED-YNTERPHSSLGYRTP 67
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
150-370 2.83e-07

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 51.64  E-value: 2.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 150 YGSPRITHELRRQGETCG-----ENRVARLMKQAKLKANigykrryFKSTVPAliADNHLQQQFVVSEPDTAWVADITYI 224
Cdd:PRK09409   66 YGYRRVWALLRRQAELDGmpainAKRVYRIMRQNALLLE-------RKPAVPP--SKRAHTGRVAVKESNQRWCSDGFEF 136
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 225 KTYEG-WLYLAVVLDLFSRKIIGWSMQPN-MSKDIVIKALLMAVWRRN----PKHEVIVHSDQGSQYASCDYREFLTANN 298
Cdd:PRK09409  137 CCDNGeRLRVTFALDCCDREALHWAVTTGgFNSETVQDVMLGAVERRFgndlPSSPVEWLTDNGSCYRANETRQFARMLG 216
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2791320920 299 LVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYEKQ 370
Cdd:PRK09409  217 LEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLRQ 287
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
150-370 1.16e-06

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 49.35  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 150 YGSPRITHELRRQGETCG-----ENRVARLMKQAKL----KANIGYKRRYFKSTVpaliadnhlqqqfVVSEPDTAWVAD 220
Cdd:PRK14702   27 YGYRRVWALLRRQAELDGmpainAKRVYRLMRQNALllerKPAVPPSKRAHTGRV-------------AVKESNQRWCSD 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791320920 221 ITYIKTYEG-WLYLAVVLDLFSRKIIGWSMQPN-MSKDIVIKALLMAVWRRN----PKHEVIVHSDQGSQYASCDYREFL 294
Cdd:PRK14702   94 GFEFCCDNGeRLRVTFALDCCDREALHWAVTTGgFNSETVQDVMLGAVERRFgndlPSSPVEWLTDNGSCYRANETRQFA 173
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2791320920 295 TANNLVPSMSRRGHCLDNAVAESFFHSLKTERVKRKVYETRNDARADLFDYIEmFYNRKRLHSHLGHVSPEEYEKQ 370
Cdd:PRK14702  174 RMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFE-HYNEWHPHSALGYRSPREYLRQ 248
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
10-45 8.90e-03

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 34.10  E-value: 8.90e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2791320920  10 FKDEAVRQVvDKGYSVPDVAKRLGISDKSLYYWVKK 45
Cdd:pfam13518   1 ERLKIVLLA-LEGESIKEAARLFGISRSTVYRWIRR 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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