|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-426 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 921.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 161 DLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 241 LDVASSEIYKDGKYHLDGEGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTK 320
Cdd:COG0148 241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 321 RLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAK 400
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 2791447233 401 YNQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 884.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 161 DLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 241 LDVASSEIYKDGKYHLDGEGkvLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTK 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 321 RLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAK 400
Cdd:PRK00077 319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398
|
410 420
....*....|....*....|....*..
gi 2791447233 401 YNQLLRIEEMLYETAQYKGDAVFYNLK 427
Cdd:PRK00077 399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-409 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 765.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 7 VVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAIIGYDATE 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 87 QVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNVDLQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 167 IMPVGAKTFSDALRSCAEVYHTLKSVLHDKG--LSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLALDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 245 SSEIYKDGKYHLDG-EGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTKRLE 323
Cdd:cd03313 242 ASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 324 KGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAKYNQ 403
Cdd:cd03313 322 KGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYNQ 401
|
....*.
gi 2791447233 404 LLRIEE 409
Cdd:cd03313 402 LLRIEE 407
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-426 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 753.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 4 IEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAIIGYD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 84 ATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNVDLQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 164 EFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 244 ASSEIY--KDGKYHLDGEGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTKR 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 322 LEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 2791447233 402 NQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
142-426 |
2.45e-160 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 453.47 E-value: 2.45e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 142 LPVPMMNILNGGAHADNNVDLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKG--LSTAVGDEGGFAPNLASNEEAL 219
Cdd:pfam00113 4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 220 EVICEAIKRAGYELgtDFKLALDVASSEIY--KDGKYHLDGEG------KVLSASEMVDFYEYLVDKYPIVSIEDGLAEE 291
Cdd:pfam00113 84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 292 DWDGWKVLTERLGKRVQLVGDDLFVTNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETE 371
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2791447233 372 DTFIADIAVAVNAGQIKTGAPARSERVAKYNQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Eno |
COG0148 |
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ... |
1-426 |
0e+00 |
|
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain] Cd Length: 426 Bit Score: 921.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:COG0148 1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNV 160
Cdd:COG0148 81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 161 DLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLA 240
Cdd:COG0148 161 DIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 241 LDVASSEIYKDGKYHLDGEGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTK 320
Cdd:COG0148 241 LDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTNPK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 321 RLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAK 400
Cdd:COG0148 321 RLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERVAK 400
|
410 420
....*....|....*....|....*.
gi 2791447233 401 YNQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:COG0148 401 YNQLLRIEEELGDAARYAGRSAFKRL 426
|
|
| eno |
PRK00077 |
enolase; Provisional |
1-427 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 234617 [Multi-domain] Cd Length: 425 Bit Score: 884.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:PRK00077 1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNV 160
Cdd:PRK00077 81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHADNNV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 161 DLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLA 240
Cdd:PRK00077 161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 241 LDVASSEIYKDGKYHLDGEGkvLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTK 320
Cdd:PRK00077 241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 321 RLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAK 400
Cdd:PRK00077 319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398
|
410 420
....*....|....*....|....*..
gi 2791447233 401 YNQLLRIEEMLYETAQYKGDAVFYNLK 427
Cdd:PRK00077 399 YNQLLRIEEELGDAARYAGKKAFKNLK 425
|
|
| enolase |
cd03313 |
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ... |
7-409 |
0e+00 |
|
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain] Cd Length: 408 Bit Score: 765.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 7 VVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAIIGYDATE 86
Cdd:cd03313 2 IKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVTD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 87 QVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNVDLQEFM 166
Cdd:cd03313 82 QRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGNKLDFQEFM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 167 IMPVGAKTFSDALRSCAEVYHTLKSVLHDKG--LSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLALDVA 244
Cdd:cd03313 162 IVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALDVA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 245 SSEIYKDGKYHLDG-EGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTKRLE 323
Cdd:cd03313 242 ASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPERLK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 324 KGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAKYNQ 403
Cdd:cd03313 322 KGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKYNQ 401
|
....*.
gi 2791447233 404 LLRIEE 409
Cdd:cd03313 402 LLRIEE 407
|
|
| eno |
TIGR01060 |
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ... |
4-426 |
0e+00 |
|
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain] Cd Length: 425 Bit Score: 753.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 4 IEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAIIGYD 83
Cdd:TIGR01060 1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 84 ATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGGAHADNNVDLQ 163
Cdd:TIGR01060 81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHADNNLDFQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 164 EFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKGLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYELGTDFKLALDV 243
Cdd:TIGR01060 161 EFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALDC 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 244 ASSEIY--KDGKYHLDGEGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERLGKRVQLVGDDLFVTNTKR 321
Cdd:TIGR01060 241 AASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 322 LEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAKY 401
Cdd:TIGR01060 321 LREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAKY 400
|
410 420
....*....|....*....|....*
gi 2791447233 402 NQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:TIGR01060 401 NQLLRIEEELGDSARYAGKNSFYRF 425
|
|
| PTZ00081 |
PTZ00081 |
enolase; Provisional |
1-421 |
0e+00 |
|
enolase; Provisional
Pssm-ID: 240259 [Multi-domain] Cd Length: 439 Bit Score: 590.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGtIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:PTZ00081 1 MSTIKSIKAREILDSRGNPTVEVDLTTEKG-VFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLK-LDGTDN-----KANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKE-----LPVPMMNI 149
Cdd:PTZ00081 80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKPtdkfvLPVPCFNV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 150 LNGGAHADNNVDLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDK-GLS-TAVGDEGGFAPNLASNEEALEVICEAIK 227
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 228 RAGYElgTDFKLALDVASSEIYKDGK--YHLD------GEGKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVL 299
Cdd:PTZ00081 240 KAGYE--GKVKICMDVAASEFYDKEKkvYDLDfknpnnDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 300 TERLGKRVQLVGDDLFVTNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIA 379
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 2791447233 380 VAVNAGQIKTGAPARSERVAKYNQLLRIEEMLYETAQYKGDA 421
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGEN 439
|
|
| PLN00191 |
PLN00191 |
enolase |
1-421 |
0e+00 |
|
enolase
Pssm-ID: 215095 [Multi-domain] Cd Length: 457 Bit Score: 570.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGTiATAAVPSGASTGMFEAVELRDGDKkRYGGKGVLQAVDNVNAKIGPAII 80
Cdd:PLN00191 25 MATITKVKARQIIDSRGNPTVEVDLHTSKGM-FRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLY---LGGFNAKELPVPMMNILNGGAHAD 157
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHAG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 158 NNVDLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDK--GLSTAVGDEGGFAPNLASNEEALEVICEAIKRAGYelgT 235
Cdd:PLN00191 183 NKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGY---T 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 236 D-FKLALDVASSEIY-KDGKYHLDGE------GKVLSASEMVDFYEYLVDKYPIVSIEDGLAEEDWDGWKVLTERlgKRV 307
Cdd:PLN00191 260 GkIKIGMDVAASEFYtKDKKYDLDFKeenndgSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--EDV 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 308 QLVGDDLFVTNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNAGQI 387
Cdd:PLN00191 338 QIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQI 417
|
410 420 430
....*....|....*....|....*....|....
gi 2791447233 388 KTGAPARSERVAKYNQLLRIEEMLYETAQYKGDA 421
Cdd:PLN00191 418 KTGAPCRSERLAKYNQLLRIEEELGDEAVYAGEN 451
|
|
| Enolase_C |
pfam00113 |
Enolase, C-terminal TIM barrel domain; |
142-426 |
2.45e-160 |
|
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063 Cd Length: 296 Bit Score: 453.47 E-value: 2.45e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 142 LPVPMMNILNGGAHADNNVDLQEFMIMPVGAKTFSDALRSCAEVYHTLKSVLHDKG--LSTAVGDEGGFAPNLASNEEAL 219
Cdd:pfam00113 4 LPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEAL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 220 EVICEAIKRAGYELgtDFKLALDVASSEIY--KDGKYHLDGEG------KVLSASEMVDFYEYLVDKYPIVSIEDGLAEE 291
Cdd:pfam00113 84 DLIVEAIEKAGYKG--KIKIAMDVASSEFYnkKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFDED 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 292 DWDGWKVLTERLGKRVQLVGDDLFVTNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETE 371
Cdd:pfam00113 162 DWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGETE 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2791447233 372 DTFIADIAVAVNAGQIKTGAPARSERVAKYNQLLRIEEMLYETAQYKGDAVFYNL 426
Cdd:pfam00113 242 DTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
|
|
| Enolase_N |
pfam03952 |
Enolase, N-terminal domain; |
4-134 |
3.71e-87 |
|
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain] Cd Length: 131 Bit Score: 261.16 E-value: 3.71e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 4 IEQVVAREILDSRGNPTVEVEVCLEDGTIATAAVPSGASTGMFEAVELRDGDKKRYGGKGVLQAVDNVNAKIGPAIIGYD 83
Cdd:pfam03952 1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2791447233 84 ATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYL 134
Cdd:pfam03952 81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
|
|
| PRK08350 |
PRK08350 |
hypothetical protein; Provisional |
1-413 |
2.65e-24 |
|
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain] Cd Length: 341 Bit Score: 102.96 E-value: 2.65e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 1 MAVIEQVVAREILDSRGNPTVEVEVCLEDGtIATAAVPSGASTGMFEAVELRdgdkkryggkgvlqAVDNVNAKIGPAII 80
Cdd:PRK08350 1 MTVIENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPIDENPSLYIAEAHR--------------AVSEVDEIIGPELI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 81 GYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGFNAKELPVPMMNILNGgahadnnv 160
Cdd:PRK08350 66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAED-------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 161 DLQEFMIMpvgaktfsdaLRSCAEVYHTLKSVlhDKGLSTavgdeggfapnlaSNEEALEVICEAIKRAGYELGTDFKLA 240
Cdd:PRK08350 138 ENFEYYVL----------VRDLMEITDVVDAV--NKILEN-------------SKEVSLEGLSKASEKAGDELGLEVALG 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 241 LDVasseiykdgKYHLDGEgKVLSasemvdfyeyLVDKYPIVSIEDGLAEEdwdgwkVLTERLG--KRVQLVGDDLFVTN 318
Cdd:PRK08350 193 IAQ---------KREMETE-KVLN----------LVEDNNIAYIKPIGDEE------LFLELIAgtHGVFIDGEYLFRTR 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 319 TKrlekgIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVVSHRSGETEDTFIADIAVAVNagqiktgAPA---RS 395
Cdd:PRK08350 247 NI-----LDRRYYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLR-------CPAmliHK 314
|
410
....*....|....*...
gi 2791447233 396 ERVAKYNQLLRIEEMLYE 413
Cdd:PRK08350 315 DSVEKINELNRIAEDLGE 332
|
|
| enolase_like |
cd00308 |
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ... |
110-389 |
3.71e-15 |
|
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.
Pssm-ID: 238188 [Multi-domain] Cd Length: 229 Bit Score: 74.29 E-value: 3.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 110 AILGVSMAVARAAAESLDLPLFLYLGGfnakelpvpmmnilnggahadnnvdlqefmimpvgaktfsdALRSCAEVYHTL 189
Cdd:cd00308 43 VISGIDMALWDLAAKALGVPLAELLGG-----------------------------------------GSRDRVPAYGSI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 190 KSVlhdkglstavgdeggfapnlasneealevicEAIKRAgyeLGTDFKLALDVASSeiykdgkyhldgegkvLSASEMV 269
Cdd:cd00308 82 ERV-------------------------------RAVREA---FGPDARLAVDANGA----------------WTPKEAI 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 270 DFYEYLvDKYPIVSIEDGLAEEDWDGWKVLTERLGkrVQLVGDDLFVTNTKRLEkGIDLGVANSILVKVNQIGTLTEAFD 349
Cdd:cd00308 112 RLIRAL-EKYGLAWIEEPCAPDDLEGYAALRRRTG--IPIAADESVTTVDDALE-ALELGAVDILQIKPTRVGGLTESRR 187
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2791447233 350 AMETAKRAGYTCVVSHRSG-ETEDTFIADIAVAV-NAGQIKT 389
Cdd:cd00308 188 AADLAEAFGIRVMVHGTLEsSIGTAAALHLAAALpNDRAIET 229
|
|
| PTZ00378 |
PTZ00378 |
hypothetical protein; Provisional |
77-416 |
7.56e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 173571 [Multi-domain] Cd Length: 518 Bit Score: 51.41 E-value: 7.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 77 PAIIGYDATEQVAIDNLMLKLDGTDNKANLGANAILGVSMAVARAAAESLDLPLFLYLGGF-----NAKELPVPMMNI-- 149
Cdd:PTZ00378 117 PRLLQLGARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALfgsltSVETFSMPQLCItf 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 150 LNGGAHADNNVDLQEFMIMPV---GAKTFSDALRSCAEVYHTLKSvlHdkglSTAVGDEGGFAPNLASN-EEALEVICEA 225
Cdd:PTZ00378 197 FGPGNPSTARLALKSVLFSPVmpsGTVLRERMQKIFAAFHHFCQS--H----NSSVRSDGSLHWDGFANlTDAVKLATEA 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 226 IKRAGYELGTDFKLAL------------DVASSEIYKDGK------YHL-DGEGKVlSASEMVDFYEYLVDKYP--IVSI 284
Cdd:PTZ00378 271 LRAVQLTPGTDVCLGLrmaasttrvpatAVADGGAWKEAKddcevlYSLfPGEPDV-TGDQLSEYVREQLQAVPdiVVYV 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 285 EDGLAEEDWDGWKVLTERLGKRVQLVGDDLFV-TNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCV- 362
Cdd:PTZ00378 350 EDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGEDEGRAVt 429
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 363 VSHRSGETEDTFIADIAVAVNAGQIKTGAPARSERVAKYNQLLRIEE------MLYETAQ 416
Cdd:PTZ00378 430 VLVQTLAGNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDelthsrMLAPEAP 489
|
|
| RspA |
COG4948 |
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane ... |
59-363 |
1.11e-04 |
|
L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 443975 [Multi-domain] Cd Length: 359 Bit Score: 44.04 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 59 YGGKGVLQAVDNVnakIGPAIIGYDATEqvaIDNLMLKLDGTDNKANlgaNAILGVSMAVARAAAESLDLPLFLYLGGFN 138
Cdd:COG4948 53 TGAEAVAAALEEA---LAPLLIGRDPLD---IEALWQRLYRALPGNP---AAKAAVDMALWDLLGKALGVPVYQLLGGKV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 139 AKELPVpmmnilngGAHadnnvdlqefmimpVGAKTFSDALRSCAEV----YHTLKsvlhdkglsTAVGDEGGfapnlas 214
Cdd:COG4948 124 RDRVPV--------YAT--------------LGIDTPEEMAEEAREAvargFRALK---------LKVGGPDP------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 215 nEEALEVIcEAIKRAgyeLGTDFKLALDVASSeiykdgkyhldgegkvLSASEMVDFYEYLvDKYPIVSIEDGLAEEDWD 294
Cdd:COG4948 166 -EEDVERV-RAVREA---VGPDARLRVDANGA----------------WTLEEAIRLLRAL-EDLGLEWIEQPLPAEDLE 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2791447233 295 GWKVLTERLgkRVQLVGDDLfVTNTKRLEKGIDLGVANSILVKVNQIGTLTEAFDAMETAKRAGYTCVV 363
Cdd:COG4948 224 GLAELRRAT--PVPIAADES-LTSRADFRRLIEAGAVDIVNIKLSKVGGLTEALRIAALAEAHGVPVMP 289
|
|
| MLE |
cd03318 |
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis, ... |
59-144 |
2.04e-03 |
|
Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by the action of chloromuconate lactonizing enzymes (Cl-MLEs). MLEs are members of the enolase superfamily characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and that is stabilized by coordination to the essential Mg2+ ion.
Pssm-ID: 239434 [Multi-domain] Cd Length: 365 Bit Score: 39.99 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2791447233 59 YGGKGVLQAVDNVNAKIGPAIIGYDATEQVAIdnlMLKLDGTdNKANLGANAilGVSMAVARAAAESLDLPLFLYLGGFN 138
Cdd:cd03318 55 WGGESPETIKAIIDRYLAPLLIGRDATNIGAA---MALLDRA-VAGNLFAKA--AIEMALLDAQGRRLGLPVSELLGGRV 128
|
....*.
gi 2791447233 139 AKELPV 144
Cdd:cd03318 129 RDSLPV 134
|
|
| |
