|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-813 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1226.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 1 MRLLKFFGWSIVAVFCGLLLGLSGAFLYLSPGLPSVEALRSIQLQIPLRVYSSDNKLIAEFGEMRRTPIRFADIPPNFIN 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 81 ALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQLTKDEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 161 ELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGKITEADY 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 241 TTAINEPLNASYHVPTPEVNAPYIAEMARAEMVGRYGSD-AYTEGFRVTTTVPSNLQEMANTALHEGLMTYDQRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEDaLYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 320 ESRLPgKTREAWTTELTKQRTISSLEPAIVTQVDKTGLQVLTRTGEEH-VSWDTMKWARPFLNTNSMGANPKQPSDVAQV 398
Cdd:COG5009 321 EAHLD-LAEEDWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGtLPLEGLKWARPYINDNRRGPAPKSASDVLKP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 399 GDLIRVQRQPDNSLKFSQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAALDNGYTAA 478
Cdd:COG5009 400 GDVIRVRPVADGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDNGYTPA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 479 SLVNDAPIVFVDEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQdLPRNLSLAL 558
Cdd:COG5009 480 TIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPNLSLAL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 559 GTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSVPKGNvvtdgiaapvaanaftvsatpGEALTAQ 638
Cdd:COG5009 559 GSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDC---------------------DAAEWDG 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 639 PAPQTPAVAERIVDGRTTYILNSMLEDVIKLGTGRRALALGRsDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFDQPES 718
Cdd:COG5009 618 AEPRLPDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGR-DIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPRS 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 719 LGRKEFGGTVALPIWMSYMGAALKDLPPHTQPEPEGILSLRVDPISGRAASPGTPGAYFELFKAEDTPPSAnelgngIAP 798
Cdd:COG5009 697 LGRGETGGRAALPIWIDFMKAALKDKPEKPFPVPEGIVTVRIDPKTGLLASPGDPDAIFEAFKPGTEPTES------ASE 770
|
810
....*....|....*
gi 2793106014 799 GSPLPADEAAPIDLF 813
Cdd:COG5009 771 DLGPDASEGTGEGLF 785
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-777 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 762.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 1 MRLLKFFgwSIVAVFCgLLLG---LSGAFLYLSPGLPSVEALRSIQLQIPLRVYSSDNKLIAEFGEMRRTPIRFADIPPN 77
Cdd:PRK11636 1 MKFVKYL--LILAVCC-ILLGagsIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 78 FINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQLTKD 157
Cdd:PRK11636 78 MVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 158 EILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGKITE 237
Cdd:PRK11636 158 EILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 238 ADYTTAINEPLNASYHVPTPEVNAPYIAEMARAEMVGRYGSDAYTEGFRVTTTVPSNLQEMANTALHEGLMTYDQRHGYR 317
Cdd:PRK11636 238 AQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 318 GPESRLPGKTREAWTTE-----LTKQRTISSLEPAIVTQVDKTGLQVLTRTGEE-HVSWDTMKWARPFLNTNSMGANPKQ 391
Cdd:PRK11636 318 GPANVLWKVGESAWDNKkitdtLKALPTYGPLLPAVVTSANPQEATAMLADGSSvALPMEGVRWARPYRSDTQQGPTPRK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 392 PSDVAQVGDLIRVqRQPDNSLKFSQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAAL 471
Cdd:PRK11636 398 VTDVVQTGQQIWV-RQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 472 DNGYTAASLVNDAPIVFVDEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQDLP 551
Cdd:PRK11636 477 DKGLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIV 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 552 RNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSV-------------PKGNVVTDGIAA 618
Cdd:PRK11636 557 HTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVAcpecdipviygdtQKSNVLENDDVE 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 619 PVAanaftVSATPGEALTAQP--APQTPAVAERivDGRTTY---ILNSMLEDVIK-------------LGTGRRALA-LG 679
Cdd:PRK11636 637 NVA-----TSQEQQNSSVPMPqlEQANQALVAQ--NGAQEYaphVINTPLAFLIKsalntnifgepgwMGTGWRAGRdLK 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 680 RSDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFD-QPESLGRK-------------EFGGTVALPIWMSYMGAALKDLP 745
Cdd:PRK11636 710 RRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDdHRRDLGRTtasgaikdqisgyEGGAKSAQPAWDDYMKAALEGVP 789
|
810 820 830
....*....|....*....|....*....|...
gi 2793106014 746 PHTQPEPEGILSLRVDPISGRAASPG-TPGAYF 777
Cdd:PRK11636 790 EQPLTPPPGIVTVNIDRSTGKLANGGnSREEYF 822
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-743 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 609.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 65 RRTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEI 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 145 LLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDW 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 225 ILGRMYKLGKITEADYTTAINEPLNASYHVPTP-EVNAPYIAEMARAEMVGRYGSDAYTEGFRVTTTVPSNLQEMANTAL 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSeQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 304 HEGLMTYDQRHGYrgpesrlpgktreawtteltkqrtisslepaivtqvdktglqvltrtgeehvswdtmkwarpflntn 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 384 smganpkqpsdvaqvgdlirvqrqpdnslkfsqipQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFK 463
Cdd:TIGR02074 254 -----------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFK 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 464 PFVYSAALDNGYTAASLVNDAPIVFvdeYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKF 543
Cdd:TIGR02074 299 PFVYAAALEKGLTPATIVNDEPITY---NGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRF 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 544 GFnKQDLPRNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPpsvpkgnvvtdgiaapvaan 623
Cdd:TIGR02074 376 GI-TSPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKP-------------------- 434
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 624 aftvsatpgealtaqpapqtpaVAERIVDGRTTYILNSMLEDVIKLGTGRRAlALGRSDIAGKTGTTNESKDAWFSGYNA 703
Cdd:TIGR02074 435 ----------------------KTTQVISPATAYIMTDMLKGVVESGTGRSA-RLPGRPVAGKTGTTQNWRDAWFVGYTP 491
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 2793106014 704 DYVTTVWTGFDQPESLGRKEFGGTVALPIWMSYMGAALKD 743
Cdd:TIGR02074 492 YYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
2.20e-87 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 274.01 E-value: 2.20e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 54 DNKLIAEFGEMRRTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTS 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 134 ERSFSRKTTEILLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLA 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 2793106014 214 NPARSKERRDWILGRMY 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-813 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 1226.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 1 MRLLKFFGWSIVAVFCGLLLGLSGAFLYLSPGLPSVEALRSIQLQIPLRVYSSDNKLIAEFGEMRRTPIRFADIPPNFIN 80
Cdd:COG5009 1 MRLLKILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLIN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 81 ALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQLTKDEIL 160
Cdd:COG5009 81 AFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 161 ELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGKITEADY 240
Cdd:COG5009 161 ELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 241 TTAINEPLNASYHVPTPEVNAPYIAEMARAEMVGRYGSD-AYTEGFRVTTTVPSNLQEMANTALHEGLMTYDQRHGYRGP 319
Cdd:COG5009 241 EAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEDaLYTGGLKVYTTLDPRLQEAAEKALRDGLLAYDRRHGYRGP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 320 ESRLPgKTREAWTTELTKQRTISSLEPAIVTQVDKTGLQVLTRTGEEH-VSWDTMKWARPFLNTNSMGANPKQPSDVAQV 398
Cdd:COG5009 321 EAHLD-LAEEDWDEALAEVPDVGDLRPAVVLEVDDKSARVGLRDGETGtLPLEGLKWARPYINDNRRGPAPKSASDVLKP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 399 GDLIRVQRQPDNSLKFSQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAALDNGYTAA 478
Cdd:COG5009 400 GDVIRVRPVADGGWRLRQIPEVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDNGYTPA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 479 SLVNDAPIVFVDEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQdLPRNLSLAL 558
Cdd:COG5009 480 TIINDAPIVFDDGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSK-LPPNLSLAL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 559 GTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSVPKGNvvtdgiaapvaanaftvsatpGEALTAQ 638
Cdd:COG5009 559 GSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEDC---------------------DAAEWDG 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 639 PAPQTPAVAERIVDGRTTYILNSMLEDVIKLGTGRRALALGRsDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFDQPES 718
Cdd:COG5009 618 AEPRLPDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGR-DIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPRS 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 719 LGRKEFGGTVALPIWMSYMGAALKDLPPHTQPEPEGILSLRVDPISGRAASPGTPGAYFELFKAEDTPPSAnelgngIAP 798
Cdd:COG5009 697 LGRGETGGRAALPIWIDFMKAALKDKPEKPFPVPEGIVTVRIDPKTGLLASPGDPDAIFEAFKPGTEPTES------ASE 770
|
810
....*....|....*
gi 2793106014 799 GSPLPADEAAPIDLF 813
Cdd:COG5009 771 DLGPDASEGTGEGLF 785
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-777 |
0e+00 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 762.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 1 MRLLKFFgwSIVAVFCgLLLG---LSGAFLYLSPGLPSVEALRSIQLQIPLRVYSSDNKLIAEFGEMRRTPIRFADIPPN 77
Cdd:PRK11636 1 MKFVKYL--LILAVCC-ILLGagsIYGLYRYIEPQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 78 FINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQLTKD 157
Cdd:PRK11636 78 MVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 158 EILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGKITE 237
Cdd:PRK11636 158 EILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 238 ADYTTAINEPLNASYHVPTPEVNAPYIAEMARAEMVGRYGSDAYTEGFRVTTTVPSNLQEMANTALHEGLMTYDQRHGYR 317
Cdd:PRK11636 238 AQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYGENAYEDGYRVYTTITRKVQQAAQQAVRNNVLDYDMRHGYR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 318 GPESRLPGKTREAWTTE-----LTKQRTISSLEPAIVTQVDKTGLQVLTRTGEE-HVSWDTMKWARPFLNTNSMGANPKQ 391
Cdd:PRK11636 318 GPANVLWKVGESAWDNKkitdtLKALPTYGPLLPAVVTSANPQEATAMLADGSSvALPMEGVRWARPYRSDTQQGPTPRK 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 392 PSDVAQVGDLIRVqRQPDNSLKFSQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAAL 471
Cdd:PRK11636 398 VTDVVQTGQQIWV-RQVDDAWWLAQVPDVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 472 DNGYTAASLVNDAPIVFVDEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQDLP 551
Cdd:PRK11636 477 DKGLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIV 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 552 RNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSV-------------PKGNVVTDGIAA 618
Cdd:PRK11636 557 HTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPKVAcpecdipviygdtQKSNVLENDDVE 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 619 PVAanaftVSATPGEALTAQP--APQTPAVAERivDGRTTY---ILNSMLEDVIK-------------LGTGRRALA-LG 679
Cdd:PRK11636 637 NVA-----TSQEQQNSSVPMPqlEQANQALVAQ--NGAQEYaphVINTPLAFLIKsalntnifgepgwMGTGWRAGRdLK 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 680 RSDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFD-QPESLGRK-------------EFGGTVALPIWMSYMGAALKDLP 745
Cdd:PRK11636 710 RRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDdHRRDLGRTtasgaikdqisgyEGGAKSAQPAWDDYMKAALEGVP 789
|
810 820 830
....*....|....*....|....*....|...
gi 2793106014 746 PHTQPEPEGILSLRVDPISGRAASPG-TPGAYF 777
Cdd:PRK11636 790 EQPLTPPPGIVTVNIDRSTGKLANGGnSREEYF 822
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
2-755 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 664.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 2 RLLKFFGWSIVAVFCGLLLGLSGAFLYLSPGLPSVEALRSIQLQIPLRVYSSDNKLIAEFGEMRRTPIRFADIPPNFINA 81
Cdd:COG0744 10 LLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPHLKDA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 82 LLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQLTKDEILE 161
Cdd:COG0744 90 VVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 162 LYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGKITEADYT 241
Cdd:COG0744 170 LYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEAD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 242 TAINEPLN-ASYHVPTPEVNAPYIAEMARAEMVGRYGSDA-YTEGFRVTTTVPSNLQEMANTALheglmtydqrhgyrgp 319
Cdd:COG0744 250 AAKAEPLTlVPPPNGAAAGKYPYFVDYVRRELEELLGEDDlYRGGLKIYTTLDPKLQKAAEKAV---------------- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 320 esrlpgktreawtteltkqrtisslepaivtqvdktglqvltrtgeehvswdtmkwarpflntnsmganpkqpsdvaqvg 399
Cdd:COG0744 --------------------------------------------------------------------------------
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 400 dlirvqrqpDNSLKFSQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAALDNGYTAAS 479
Cdd:COG0744 314 ---------KNVLPEGKPGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEQGYTPAT 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 480 LVNDAPIvfvdEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKqDLPRNLSLALG 559
Cdd:COG0744 385 TVDDEPV----TFPGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGITS-PLDPNPSLALG 459
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 560 TATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSvpkgnvvtdgiaapvaanaftvsatpgealtaqp 639
Cdd:COG0744 460 TSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKC---------------------------------- 505
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 640 apqtpavaERIVDGRTTYILNSMLEDVIKLGTGRRALALGRsDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFDQPESL 719
Cdd:COG0744 506 --------EQVISPEVAYLMTDMLQDVVTSGTGRAARLPGR-PVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPM 576
|
730 740 750
....*....|....*....|....*....|....*.
gi 2793106014 720 GrKEFGGTVALPIWMSYMGAALKDLPPHTQPEPEGI 755
Cdd:COG0744 577 G-YVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSGV 611
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
65-743 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 609.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 65 RRTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEI 144
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 145 LLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDW 224
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 225 ILGRMYKLGKITEADYTTAINEPLNASYHVPTP-EVNAPYIAEMARAEMVGRYGSDAYTEGFRVTTTVPSNLQEMANTAL 303
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSeQYKAPYFVDYVIQELEEEYGEELYTGGLKIYTTLDLDAQKAAEKVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 304 HEGLMTYDQRHGYrgpesrlpgktreawtteltkqrtisslepaivtqvdktglqvltrtgeehvswdtmkwarpflntn 383
Cdd:TIGR02074 241 NTGLRVAGRRDGD------------------------------------------------------------------- 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 384 smganpkqpsdvaqvgdlirvqrqpdnslkfsqipQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFK 463
Cdd:TIGR02074 254 -----------------------------------DLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFK 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 464 PFVYSAALDNGYTAASLVNDAPIVFvdeYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKF 543
Cdd:TIGR02074 299 PFVYAAALEKGLTPATIVNDEPITY---NGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRF 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 544 GFnKQDLPRNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPpsvpkgnvvtdgiaapvaan 623
Cdd:TIGR02074 376 GI-TSPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKP-------------------- 434
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 624 aftvsatpgealtaqpapqtpaVAERIVDGRTTYILNSMLEDVIKLGTGRRAlALGRSDIAGKTGTTNESKDAWFSGYNA 703
Cdd:TIGR02074 435 ----------------------KTTQVISPATAYIMTDMLKGVVESGTGRSA-RLPGRPVAGKTGTTQNWRDAWFVGYTP 491
|
650 660 670 680
....*....|....*....|....*....|....*....|
gi 2793106014 704 DYVTTVWTGFDQPESLGRKEFGGTVALPIWMSYMGAALKD 743
Cdd:TIGR02074 492 YYVTAVWVGYDDKKTLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
1-787 |
3.84e-107 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 346.05 E-value: 3.84e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 1 MRLLKFFGWSIVAVFCGLLLGLSGAFL-YLSPgLPSVEalrsiQLQIPLRVYSSDNKLIAEF---GEMRRTPIRFADIPP 76
Cdd:COG4953 2 KRARLRRRRLLALLLALLLLALALWALdRLFP-LPLLF-----AVPYSTVVLDRDGTLLRAFlaaDGQWRLPVPLDEVSP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 77 NFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKnffLT--SERSFSRKTTEILLALQIERQL 154
Cdd:COG4953 76 RYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRY 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 155 TKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLGK 234
Cdd:COG4953 153 SKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGV 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 235 ITEADYTTAINEPLNASYHvPTPEVnAPYIAEMARAEmvgrygsdaYTEGFRVTTTVPSNLQEMANtalheglmtydqrh 314
Cdd:COG4953 233 IDAEEAALALLEPVPARRR-PLPQL-APHLARRLLRQ---------LPGGTRIRTTLDAGLQRRLE-------------- 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 315 gyrgpesrlpgktreawtteltkqrtisslepaivtqvdktglqvltrtgeehvswdtmkwarpflntnsmganpkqpsd 394
Cdd:COG4953 --------------------------------------------------------------------------------
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 395 vAQVGDLIRVQRQPdnslkfsqiPQVQGALVSLDPQNGAIRSLVGGFAF---EQSNYNRAMQAKRQPGSSFKPFVYSAAL 471
Cdd:COG4953 288 -RLVRRYVRRLKQN---------GIHNAAVLVVDNRTGEVLAYVGSADFfdaSRQGQVDMVRALRSPGSTLKPFLYGLAL 357
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 472 DNGY-TAASLVNDAPIVFvdeyldKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFnKQDL 550
Cdd:COG4953 358 DQGLiHPETLLADVPTSF------GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGL-RLLL 430
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 551 PR----NLSLALGTATLTPMEIATGWSTFANGGykitpyiidkiesrngdtlfVANPPSVpkgnvvtdgiaapvaanaft 626
Cdd:COG4953 431 PPaehyGLSLILGGAEVTLEELVGLYAALARGG--------------------EARPLRL-------------------- 470
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 627 vsaTPGEALTAQPapqtpavaeRIVDGRTTYILNSMLEDViklgtGRRALALGRSD------IAGKTGTTNESKDAWFSG 700
Cdd:COG4953 471 ---LAGEPASPGR---------RLLSPGAAWLVRDILSDV-----PRPDGAFGWRAldspppIAWKTGTSYGFRDAWAVG 533
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 701 YNADYVTTVWTG-FDqpeSLGRKE-FGGTVALPIWMSYMGAALKDLPPHTQPEPEGILSLRVDPISGRAASPGTPGAYFE 778
Cdd:COG4953 534 FTGRYTVGVWVGnPD---GTPVPGlTGAEAAAPLLFDIFDLLPASRWPLPFPPPAGLLRVEVCAPSGLLAGPNCPQRVTE 610
|
....*....
gi 2793106014 779 LFKAEDTPP 787
Cdd:COG4953 611 WFIPGTSPP 619
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
54-230 |
2.20e-87 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 274.01 E-value: 2.20e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 54 DNKLIAEFGEMRRTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTS 133
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 134 ERSFSRKTTEILLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLA 213
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 2793106014 214 NPARSKERRDWILGRMY 230
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
65-792 |
4.01e-82 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 278.15 E-value: 4.01e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 65 RRTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEI 144
Cdd:TIGR02073 32 WRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQLARLLDPELSRTLTGKLRQM 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 145 LLALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDW 224
Cdd:TIGR02073 112 WRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQAPSARRLDRLPKAAKAARDR 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 225 ILGRMYKLGKITEADYTTAINEPLNASYHvPTPEVnAPYIAEMARAEMVGRYGSdaytegfrVTTTVPSNLQEMANTALh 304
Cdd:TIGR02073 192 LLDRMVEQGPDDSEQVALAALEPLPALPE-PLPQL-APHFALKLLRARPEIASV--------IVSTLDADLQRRLEELA- 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 305 eglmtydqrhgyrgpesrlpgktrEAWTTELtKQRTISSLepaivtqvdktglqvltrtgeehvswdtmkwarpflntns 384
Cdd:TIGR02073 261 ------------------------RRYLSAL-RPRGISNL---------------------------------------- 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 385 mganpkqpsdvaqvgdlirvqrqpdnslkfsqipqvqgALVSLDPQNGAIRSLVGGFAFEQ-SNYNR--AMQAKRQPGSS 461
Cdd:TIGR02073 276 --------------------------------------AILVVDNRSGAVLAYVGSADFFDdSNSGQvdGVRAPRSPGST 317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 462 FKPFVYSAALDNGY-TAASLVNDAPIVFVDeyldkvWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYI 540
Cdd:TIGR02073 318 LKPFLYALALDDGLlHPDSLLKDVPLRFGD------YAPENFDKTFHGPVPAREALARSLNIPAVRLLERVGPPRFADFL 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 541 SKFGFN----KQDLPrNLSLALGTATLTPMEIATGWSTFANGgykitpyiidkiesrngdtlfvanppsvpkgnvvtdGI 616
Cdd:TIGR02073 392 RQAGLNllkpKSDYY-GLSLALGGAEITLQDLANLYAMLANQ------------------------------------GL 434
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 617 AAPvaanaftvsatpgeaLTAQPAPQTPAVAERIVDGRTTYILNSMLEDviklgTGRRALALGRSDIAG------KTGTT 690
Cdd:TIGR02073 435 SGP---------------LRFLQTDAKRPERERLLSPGAAWIVLDILKD-----RPRPDDTLPLSALPTrlplawKTGTS 494
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 691 NESKDAWFSGYNADYVTTVWTG-FDQPESLGrkEFGGTVALPIWMSYMGAALKDLPPhtqPEPEGILSLRVDPISGRAAS 769
Cdd:TIGR02073 495 YGFRDAWAAGVSGRYTIGVWVGnFDGKPNPG--FFGAAAAAPLLFDILDALQASEAS---TLPRPLKEVPGCLVLGNLPI 569
|
730 740
....*....|....*....|...
gi 2793106014 770 PGTPGAYFELFKAEDTPPSANEL 792
Cdd:TIGR02073 570 LPCPEQISTWFLPGGSPPTLSEP 592
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
54-761 |
7.52e-74 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 257.78 E-value: 7.52e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 54 DNKLIAEF----GEMRRTPIRfADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNF 129
Cdd:PRK09506 196 DPRLITMLqspnGEQRLFVPR-SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 130 FLTSERSFSRKTTEILLALQIERQLTKDEILELYVNKIYLG----NRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKA 205
Cdd:PRK09506 275 FLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKG 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 206 PSRFNPLANPARSKERRDWILGRMYKLGKITEADYTTAINEPLNASyhvPTPEVNAPYIA--EMARAEMVGRYGSDAYT- 282
Cdd:PRK09506 355 ASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQ---PKGGVISPQPAfmQMVRQELQAKLGDKVKDl 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 283 EGFRVTTTVPSNLQEMANTALHEGLmtydqrhgyrgpesrlpgktreawtTELTKQRTISSLEPAIVTqVDktglqvltr 362
Cdd:PRK09506 432 SGVKIFTTLDPVSQDAAEKAVEEGI-------------------------PALKKQRKLSDLETAMVV-VD--------- 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 363 tgeehvswdtmkwarpflntnsmganpkqpsdvaqvgdlirvqrqpdnslKFSqipqvqgalvsldpqnGAIRSLVGGFA 442
Cdd:PRK09506 477 --------------------------------------------------RFS----------------GEVRAMVGGSE 490
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 443 FEQSNYNRAMQAKRQPGSSFKPFVYSAALD--NGYTAASLVNDAPIVfVDEYLDKVWRPKNDTNTFLGPIRMREALYKSR 520
Cdd:PRK09506 491 PQFAGYNRAMQARRSIGSLAKPATYLTALSqpDKYRLNTWIADAPIS-LRQPNGQVWSPQNDDRRFSGRVMLVDALTRSM 569
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 521 NLVSIRLLQALGVDRTIDYISKFGFNKQDLPRNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFv 600
Cdd:PRK09506 570 NVPTVNLGMALGLPAVTDTWIKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLY- 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 601 anppsvpkgnvvtdgiaapvaanaftvsatpgealtaQPAPQtpavAERIVDGRTTYILNSMLEDVIKLGTGRR-ALALG 679
Cdd:PRK09506 649 -------------------------------------QSFPQ----AERAVPAQAAYLTLYTMQQVVQRGTGRQlGAKYP 687
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 680 RSDIAGKTGTTNESKDAWFSGYNADYVTTVWTGFD--QPESLgrkeFGGTVALPIWMSYMgAALKDLPPHTQPePEGILS 757
Cdd:PRK09506 688 NLHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDnnQPTKL----YGASGAMTIYQRYL-ENQTPTPLNLTP-PEDIVD 761
|
....
gi 2793106014 758 LRVD 761
Cdd:PRK09506 762 MGVD 765
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
75-737 |
6.76e-68 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 239.75 E-value: 6.76e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 75 PPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQL 154
Cdd:PRK14850 166 PEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFY 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 155 TKDEILELYVNKIYLG----NRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMY 230
Cdd:PRK14850 246 SKDRILELYLNEVYLGqdgnEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLY 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 231 KLGKITEADYTTAINEPLNASyhvPTPEVNAPYIAEMaraemvgrygsdaytegfrvtTTVPSNLQEMANTALHEglmty 310
Cdd:PRK14850 326 KQKVITRKLYKDLCSRPLNVQ---SKGNIISSHPAFI---------------------QLVCEEFHKKIHYPFKN----- 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 311 dqrhgyrgpesrLPGkTREAWTTELTKQRTIsslEPAIvtqvdKTGLQVLTRtgeehvswdtmkwarpflntnsmganpk 390
Cdd:PRK14850 377 ------------FSG-TKIFTTLDYISQNAA---EQAV-----KIGIPILKR---------------------------- 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 391 qpsdvaqvgdlirvqrqpdnslKFsQIPQVQGALVSLDPQNGAIRSLVGGFAFEQSNYNRAMQAKRQPGSSFKPFVYSAA 470
Cdd:PRK14850 408 ----------------------KK-RLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTA 464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 471 LD--NGYTAASLVNDAPIvFVDEYLDKVWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQ 548
Cdd:PRK14850 465 LSqpEKYHLNTWISDTPI-SIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSN 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 549 DLPRNLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFvanppsvpkgnvvtdgiaapvaanaftvs 628
Cdd:PRK14850 544 YITPLPSISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLY----------------------------- 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 629 atpgealtaQPAPQTpavaERIVDGRTTYILNSMLEDVIKLGTGRR-ALALGRSDIAGKTGTTNESKDAWFSGYNADYVT 707
Cdd:PRK14850 595 ---------QNFPQS----KHVESSQASYLTLYAMQQVVKSGTAKSlGTIFKEFSLAGKTGTTNNLVDSWFVGIDGKQVV 661
|
650 660 670
....*....|....*....|....*....|
gi 2793106014 708 TVWTGFDQPESlgRKEFGGTVALPIWMSYM 737
Cdd:PRK14850 662 ITWIGRDNNHT--TKLYGSSGAMKIYKRYL 689
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
66-712 |
5.52e-50 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 188.37 E-value: 5.52e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 66 RTPIRFADIPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKnFFLTSERSFSRKTTEIL 145
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR-LLDPHPRTFGGKIRQLW 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 146 LALQIERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWI 225
Cdd:PRK11240 141 RALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKV 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 226 LGRMYKLGKITEADYTTAINEPL-NASYHVPTPevnAPYIAEMaraeMVGRYGSDaytegfRVTTTVPSNLQ----EMAn 300
Cdd:PRK11240 221 LERMAEQGVWSAEQVKESREEPVwLAPRQMPQL---APLFARM----MLGKSKSD------KIVTTLDAGLQrrleDLA- 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 301 talheglmtydqrhgyRGPESRLPGKTREAwtteltkqrtisslepaiVTQVDKTGLQVLTRTGeehvSWDtmkwarpfL 380
Cdd:PRK11240 287 ----------------LNWKGRLPPRSSLA------------------MIVVDHTDMAVRGWVG----SVD--------L 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 381 NTNSmganpkqpsdvaqvgdlirvqrqpdnslKFSQIPQVQgalvsldpqngAIRSlvggfafeqsnynramqakrqPGS 460
Cdd:PRK11240 321 NDDS----------------------------RFGHVDMVN-----------AIRS---------------------PGS 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 461 SFKPFVYSAALDNGYT-AASLVNDAPIVFVDeyldkvWRPKNDTNTFLGPIRMREALYKSRNLVSIRLLQALGVDRTIDY 539
Cdd:PRK11240 341 VLKPFVYGLALDDGLIhPASLLQDVPRRTGD------YRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAK 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 540 ISKFGFNKQdLPR----NLSLALGTATLTPMEIATGWSTFANGGykitpyiidkiesrngdtlfvanppsvpkgnvvtdg 615
Cdd:PRK11240 415 LRNVGLPLY-LPAgaepNLSLILGGAGARLEDMVAAYSAFARHG------------------------------------ 457
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 616 iaapvaaNAFTVSATPGEALTAQP--APQTPAVAERIVDGRTTYILNSMLEDVIKLgtgrralalgrsdiAGKTGTTNES 693
Cdd:PRK11240 458 -------KAAKLRLQPDDPLLERPlmSPGAAWIIRRIMADEAQPLPDAALPRVVPL--------------AWKTGTSYGY 516
|
650
....*....|....*....
gi 2793106014 694 KDAWFSGYNADYVTTVWTG 712
Cdd:PRK11240 517 RDAWAIGVNARYVIGIWTG 535
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
74-233 |
8.38e-36 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 135.28 E-value: 8.38e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 74 IPPNFINALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQSGGSTITMQVAKNFFLTSERSFSRKTTEILLALQIERQ 153
Cdd:TIGR02070 63 ISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETW 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 154 LTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIRDVSLAQMAMIAGLPKAPSRFNPLANPARSKERRDWILGRMYKLG 233
Cdd:TIGR02070 143 WSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQMGYLG 222
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
72-246 |
1.52e-33 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 128.77 E-value: 1.52e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 72 ADIPPNFIN-ALLSAEDDNFANHYGVDPGSLMRAATQLIKSGHIQsGGSTITMQVAKNFFLTSERSFSRKTTEILLALQI 150
Cdd:PRK13481 50 ADNMPEYVKgAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQ-GGSTITQQVVKNYFYDNERSFTRKVKELFVAHRV 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 151 ERQLTKDEILELYVNKIYLGNRAYGIEAAAQVYYGKSIR-------DVSLAQMAMIAGLPKAPSRFNPLANPARSKERRD 223
Cdd:PRK13481 129 EKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNknsttmsHITVLQSAILASKVNAPSVYNINDMSENFTQRVS 208
|
170 180
....*....|....*....|...
gi 2793106014 224 WILGRMYKLGKITEADYTTAINE 246
Cdd:PRK13481 209 TNLEKMKQQNYINETQYQQAMSQ 231
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
422-746 |
1.62e-32 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 133.41 E-value: 1.62e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 422 GALVSLDPQNGAIRSLVGGFAFEQSNY---------NRAMQAKRQPGSSFKPFVYSAALDNG-YTAASLVNDAPIVFVDE 491
Cdd:COG0768 249 GAVVVMDPKTGEILAMASYPSFDPNLFvggpdeplrNRAVQGTYEPGSTFKPFTAAAALEEGvITPDTTFDCPGYYRVGG 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 492 YLDKVWRPKNdtntfLGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQ---DLP----------------R 552
Cdd:COG0768 329 RTIRDWDRGG-----HGTLTLTEALAKSSNVGFYKLALRLGIDKLYDYLKKFGLGQKtgiDLPgeasgllpspkrwypgE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 553 NLSLALGTA-TLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLfvanppsvpkgnvvtdgiaapvaanaftvsatp 631
Cdd:COG0768 404 TATMSIGQGlSVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVV--------------------------------- 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 632 gealtaqpaPQTPAVAERIVDGRTTYILNSMLEDVI--KLGTGRRALALGRSdIAGKTGT-------TNESKD----AWF 698
Cdd:COG0768 451 ---------KEEPEVLRRVISPETAETVREGMEGVVnePGGTARRAAIPGYR-VAGKTGTaqvvdigNGGYYKgrhiASF 520
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2793106014 699 SGY----NADYVTTVWtgFDQPeslGRKEFGGTVALPIWMSYMGAALKDLPP 746
Cdd:COG0768 521 VGFapadNPRYAVAVV--VENP---GGGAYGGTVAAPVFREIMEAYLRLLGP 567
|
|
| PCB_OB |
pfam17092 |
Penicillin-binding protein OB-like domain; |
316-420 |
2.00e-30 |
|
Penicillin-binding protein OB-like domain;
Pssm-ID: 465343 [Multi-domain] Cd Length: 111 Bit Score: 115.81 E-value: 2.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 316 YRGPESRL-----PGKTREAWTTELTKQRTISSLEPAIVTQVDKTGLQVLTRTGEEH-VSWDTMKWARPFLNTNSMGANP 389
Cdd:pfam17092 1 YRGPEAHLdlpadWAERLAAIDEALADLPDVGGLRPAVVLSVSPKSARVGLRDGETGtIPGEGLRWARPYLSDKRQGPAP 80
|
90 100 110
....*....|....*....|....*....|.
gi 2793106014 390 KQPSDVAQVGDLIRVQRQPDNSLKFSQIPQV 420
Cdd:pfam17092 81 KSASDVLKPGDVIRVRPNGDGGWRLRQVPEV 111
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
422-732 |
3.75e-27 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 112.51 E-value: 3.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 422 GALVSLDPQNGAIRSLVGG-----FAFEQSNYNRAMQAKRQPGSSFKPFVYSAALDNG-YTAASLVNDAPIVFVDeylDK 495
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKpsydpNGFIGPLRNRAVTSRYEPGSTFKPFTALAALDNGvLKPDETIFDWPGKQQG---GK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 496 VWRPKNDTNTFLGPirMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQD-----------LPRNLSLALGTA--- 561
Cdd:pfam00905 78 SIGDWNQDQVGIGT--LRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTgiglpgenagyLTPYWLEGATASfgi 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 562 --TLTPMEIATGWSTFANGGYKITPYIIDKIESRngdtlfvaNPPSVPKGNVVTDGIAApvaanaftvsatpgealtaqp 639
Cdd:pfam00905 156 glTITPLQQAQAYAAIANGGKLVPPHLVKSIEDK--------VDPKVLNKLPISKSTAE--------------------- 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 640 apqtpavaerivdgrttyILNSMLEDVIKLGTGRRALALGRSDIAGKTGTT-----------NESKDAWFSGY----NAD 704
Cdd:pfam00905 207 ------------------KVKDMLRLVVNDGTGTGTAAVPGYKVAGKTGTAqvagpkgggyyDGAQIGWFVGYapadNPK 268
|
330 340
....*....|....*....|....*...
gi 2793106014 705 YVTTVwtGFDQPEslgrKEFGGTVALPI 732
Cdd:pfam00905 269 YAFAV--LIDDPK----RYYGGKVAAPI 290
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
422-732 |
1.30e-17 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 87.19 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 422 GALVSLDPQNGAIRSLV-----------GGFAFEQSN----------YNRAMQAKRQPGSSFKPFVYSAALDNG-YTAAS 479
Cdd:TIGR03423 249 GAVVVMDPRTGEILAMVstpsfdpnlfvDGISSKDYKallndpdrplLNRAIQGVYPPGSTFKPVVALAALEEGvITPET 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 480 LVNDaPIVFvdEYLDKVWRPKNDTNTflGPIRMREALYKSRNLVSIRLLQALGVDRTIDYISKFGFNKQ---DLPR---- 552
Cdd:TIGR03423 329 RIYC-PGYF--QLGGRRFRCWKRGGH--GRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGFGQKtgiDLPGeksg 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 553 ----------------------NLSLALGTATLTPMEIATGWSTFANGGYKITPYIIDKIESRNGDTLFVANPPSVPKGN 610
Cdd:TIGR03423 404 lvpsrewkrkrfgqpwypgdtlNVSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPLP 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 611 VvtdgiaapvaanaftvsatpgealtaqpapqTPAVAERIVDGrttyilnsmLEDVIKL--GTGRRALALGRSDIAGKTG 688
Cdd:TIGR03423 484 I-------------------------------SPENLDVVREG---------MRDVVNGpgGTARRARLGLPYKMAGKTG 523
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2793106014 689 T-------TNESKD-----------AWFSGYnADYvttvwtgfDQPE-----SLGRKEFGGTVALPI 732
Cdd:TIGR03423 524 TaqvvslkQGEKYDaeqiperlrdhALFVAF-APY--------DNPKiavavIVEHGGGGSSAAAPI 581
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
404-742 |
3.10e-05 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 47.51 E-value: 3.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 404 VQRQPDNSLKFSQIPQvqGALVSLDPQNGAIRSLVGGFAFEQSNY---------NRAMQAKRQPGSSFKPFVYSAALDNG 474
Cdd:PRK15105 243 VYRELNNAVAFNKAES--GSAVLVDVNTGEVLAMANSPSYNPNNLsgtpkdamrNRAITDVFEPGSTVKPMVVMTALQRG 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 475 YTAA-SLVNDAPIVFVDEYLDKVWRPKNDTNTFLgpirmreaLYKSRNLVSIRLLQALGVDRTIDYISKFGFNKqdlPRN 553
Cdd:PRK15105 321 VVKEnSVLNTVPYRINGHEIKDVARYSELTLTGV--------LQKSSNVGVSKLALAMPSSALVDTYSRFGLGK---ATN 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 554 LSLALGTATLTPMEiaTGWS-----TFANG-GYKITPYIIDKIESRNGdTLFVANPPSVPKgnvvtdgIAAPVaanaftv 627
Cdd:PRK15105 390 LGLVGERSGLYPQK--QRWSdieraTFSFGyGLMVTPLQLARVYATIG-SYGIYRPLSITK-------VDPPV------- 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793106014 628 satPGEALTAQPAPQTpavaerivdgrttyiLNSMLEDVIKLGTGRRALALGRSDIAGKTGTTNEskdawfSGYNADYVT 707
Cdd:PRK15105 453 ---PGERVFPESIVRT---------------VVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKK------VGPDGRYIN 508
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2793106014 708 T--VWTGFDQPESLGR-------------KEFGGTVALPIWMSYMGAALK 742
Cdd:PRK15105 509 KyiAYTAGVAPASQPRfalvvvindpqagKYYGGAVSAPVFGAIMGGVLR 558
|
|
| |
