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Conserved domains on  [gi|2793869779|ref|WP_372048986|]
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tetratricopeptide repeat protein [Vibrio atlanticus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
2-132 1.47e-30

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 109.63  E-value: 1.47e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790    86 ALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKA 165

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSASKGNSYAKYHLSLL 132
Cdd:COG0790   166 AEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRL 216
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
2-132 1.47e-30

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 109.63  E-value: 1.47e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790    86 ALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKA 165

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSASKGNSYAKYHLSLL 132
Cdd:COG0790   166 AEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRL 216
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 56-86 2.35e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 36.38  E-value: 2.35e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 2793869779   56 HLGYLYEYGYGVGQDYEQAKRYYKQAVQLED 86
Cdd:smart00671   6 NLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 16-48 2.86e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 35.96  E-value: 2.86e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2793869779  16 YAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQ 48
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
2-132 1.47e-30

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 109.63  E-value: 1.47e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790    86 ALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKA 165

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSASKGNSYAKYHLSLL 132
Cdd:COG0790   166 AEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRL 216
TPR COG0790
TPR repeat [General function prediction only];
2-118 1.68e-27

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 101.54  E-value: 1.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790   122 ALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA 201

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSA 118
Cdd:COG0790   202 AEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAA 238
TPR COG0790
TPR repeat [General function prediction only];
2-132 2.10e-27

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 101.54  E-value: 2.10e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790    50 AAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKA 129

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSASKGNSYAKYHLSLL 132
Cdd:COG0790   130 AEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVL 180
TPR COG0790
TPR repeat [General function prediction only];
2-132 2.79e-14

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 66.88  E-value: 2.79e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQFYSLAFVHLGYLYEYGYGVGQDYEQAKRYYKQA 81
Cdd:COG0790    14 AAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKA 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2793869779  82 VQLEDAKGELRLALLYLRGQGGAVDKEKAILLLQSSASKGNSYAKYHLSLL 132
Cdd:COG0790    94 AEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLL 144
TPR COG0790
TPR repeat [General function prediction only];
2-48 1.11e-06

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 46.07  E-value: 1.11e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2793869779   2 AFSLYKQAAEQNHMYAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQ 48
Cdd:COG0790   194 ALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 56-86 2.35e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 36.38  E-value: 2.35e-04
                           10        20        30
                   ....*....|....*....|....*....|.
gi 2793869779   56 HLGYLYEYGYGVGQDYEQAKRYYKQAVQLED 86
Cdd:smart00671   6 NLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 16-48 2.86e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 35.96  E-value: 2.86e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2793869779  16 YAQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQ 48
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAEL 34
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 17-48 4.54e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 4.54e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2793869779   17 AQNNLAQMYERGHGTPTNFTKAKYWFEKSSNQ 48
Cdd:smart00671   3 AQYNLGQMYEYGLGVPKDLEKALEYYKKAAEL 34
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 57-84 1.58e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.03  E-value: 1.58e-03
                          10        20
                  ....*....|....*....|....*...
gi 2793869779  57 LGYLYEYGYGVGQDYEQAKRYYKQAVQL 84
Cdd:pfam08238   7 LGYLYLYGLGVPKDPEKALEWYEKAAEL 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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