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Conserved domains on  [gi|2793869784|ref|WP_372048991|]
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hypothetical protein [Vibrio atlanticus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
49-157 1.13e-25

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 103.47  E-value: 1.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  49 DPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGNQRAPIEV 128
Cdd:COG0790   134 DADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNL 213

                          90       100
                  ....*....|....*....|....*....
gi 2793869784 129 AKLYESSLEKEllKPLDEAQLWYEAALKN 157
Cdd:COG0790   214 GRLYLNGEGVE--KDLEKALRWLRKAAEQ 240
PHA02624 super family cl33693
large T antigen; Provisional
 313-361 5.15e-04

large T antigen; Provisional


The actual alignment was detected with superfamily member PHA02624:

Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 41.89  E-value: 5.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2793869784 313 LFGYTPSSIPNQKSIKIRYKQLSKIYHPDGYGCDEEMKRLnNSLKTILK 361
Cdd:PHA02624   16 LLGLPMAAWGNLPLMRKAYLRKCKEYHPDKGGDEEKMKRL-NSLYKKLQ 63
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
49-157 1.13e-25

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 103.47  E-value: 1.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  49 DPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGNQRAPIEV 128
Cdd:COG0790   134 DADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNL 213

                          90       100
                  ....*....|....*....|....*....
gi 2793869784 129 AKLYESSLEKEllKPLDEAQLWYEAALKN 157
Cdd:COG0790   214 GRLYLNGEGVE--KDLEKALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 86-121 1.33e-08

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 50.25  E-value: 1.33e-08
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2793869784   86 ADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGN 121
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 86-120 2.46e-08

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 49.44  E-value: 2.46e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2793869784  86 ADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQG 120
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
PHA02624 PHA02624
large T antigen; Provisional
 313-361 5.15e-04

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 41.89  E-value: 5.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2793869784 313 LFGYTPSSIPNQKSIKIRYKQLSKIYHPDGYGCDEEMKRLnNSLKTILK 361
Cdd:PHA02624   16 LLGLPMAAWGNLPLMRKAYLRKCKEYHPDKGGDEEKMKRL-NSLYKKLQ 63
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
49-157 1.13e-25

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 103.47  E-value: 1.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  49 DPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGNQRAPIEV 128
Cdd:COG0790   134 DADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNL 213

                          90       100
                  ....*....|....*....|....*....
gi 2793869784 129 AKLYESSLEKEllKPLDEAQLWYEAALKN 157
Cdd:COG0790   214 GRLYLNGEGVE--KDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
49-161 2.34e-25

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 102.70  E-value: 2.34e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  49 DPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGNQRAPIEV 128
Cdd:COG0790    62 GAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNL 141

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2793869784 129 AKLYESSLEKEllKPLDEAQLWYE-AALKNNPKA 161
Cdd:COG0790   142 GLLYLNGEGVP--KDPAKAAEWYRkAAEQGDADA 173
TPR COG0790
TPR repeat [General function prediction only];
49-170 2.64e-25

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 102.31  E-value: 2.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  49 DPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGNQRAPIEV 128
Cdd:COG0790    98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNL 177

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2793869784 129 AKLYESSLEKEllKPLDEAQLWYE-AALKNNPKAEDGYNRILE 170
Cdd:COG0790   178 GVLYENGRGVP--KDPAKALEWYRkAAEQGDADAQYNLGRLYL 218
TPR COG0790
TPR repeat [General function prediction only];
35-161 2.84e-14

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 71.50  E-value: 2.84e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793869784  35 AESNVAFSIESQPQDPVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGNADAQFRLGEWYLAGSGVEQSNKLALEWFI 114
Cdd:COG0790    12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2793869784 115 KSALQGNQRAPIEVAKLYESSLEKEllKPLDEAQLWYE-AALKNNPKA 161
Cdd:COG0790    92 KAAEQGDAEAQYNLGLMYEEGLGVP--QDYAKALEWYEkAAEQGDADA 137
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 86-121 1.33e-08

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 50.25  E-value: 1.33e-08
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2793869784   86 ADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQGN 121
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 86-120 2.46e-08

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 49.44  E-value: 2.46e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2793869784  86 ADAQFRLGEWYLAGSGVEQSNKLALEWFIKSALQG 120
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 50-85 7.47e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 42.16  E-value: 7.47e-06
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 2793869784   50 PVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENGN 85
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 50-84 3.80e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 40.20  E-value: 3.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2793869784  50 PVSQYQLAQAYESGNDVPLSTNDAFYWYSQSAENG 84
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
PHA02624 PHA02624
large T antigen; Provisional
 313-361 5.15e-04

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 41.89  E-value: 5.15e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2793869784 313 LFGYTPSSIPNQKSIKIRYKQLSKIYHPDGYGCDEEMKRLnNSLKTILK 361
Cdd:PHA02624   16 LLGLPMAAWGNLPLMRKAYLRKCKEYHPDKGGDEEKMKRL-NSLYKKLQ 63
PHA03102 PHA03102
Small T antigen; Reviewed
 311-353 9.24e-04

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 39.27  E-value: 9.24e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2793869784 311 CALFGYTPSSIPNQKSIKIRYKQLSKIYHPDGYGCDEEMKRLN 353
Cdd:PHA03102    8 MDLLGLPRSAWGNLPLMRKAYLRKCLEFHPDKGGDEEKMKELN 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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