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Conserved domains on  [gi|2793953937|ref|WP_372116340|]
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helix-turn-helix domain-containing protein, partial [Vibrio sp. 10N.261.51.E5]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_ISNCY_2 super family cl41340
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
1-164 1.09e-64

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


The actual alignment was detected with superfamily member NF033594:

Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 207.33  E-value: 1.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937   1 YVDRAGIF------GGPKRCHFSQMQRACEELGIEIIFANSPQGKGRIERAFDTFQDRLVPELRLAGVTDMISANNYLQN 74
Cdd:NF033594  192 YSDKHSVFrvneeeLAGKGDGLTQFGRALKELGIEIICANSPQAKGRVERANQTLQDRLVKELRLAGISTIEAANEALLP 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937  75 TFIPEYWATTLTVNAKlMRSEHTPVPKYLNIDAICIQKEYRKIRRDHTFSYANAMYQIT-SPLRHSIVSQQVELRKQLDG 153
Cdd:NF033594  272 EFIPDFNRRFAKPPAS-PEDAHRPLPPDEDLDLILCWREERKVSNGLTFSYDNKLYQLEdTPGNRRLIGKKVEVVEYPDG 350
                         170
                  ....*....|.
gi 2793953937 154 GFTAYFADREL 164
Cdd:NF033594  351 RIELRADGRLL 361
Csa3 super family cl34607
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
175-292 1.36e-07

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


The actual alignment was detected with superfamily member COG3415:

Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 52.16  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 175 RKEYGEEVQKKIEAIELANELGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYgQSHNNNRIDEKTRNIVISLTLK 254
Cdd:COG3415    18 RKTKDAREARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRYREGGLAGLKDRP-RGGRPSKLSDEQRERLLELLRE 96
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2793953937 255 S-----PHLTSIRISGEMRKRFNISISHSTVRNIWLEEKLNTR 292
Cdd:COG3415    97 KspdqgSRWTLAELAELLEEEFGVEVSPSTVRRLLKRLGLSYK 139
 
Name Accession Description Interval E-value
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
1-164 1.09e-64

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 207.33  E-value: 1.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937   1 YVDRAGIF------GGPKRCHFSQMQRACEELGIEIIFANSPQGKGRIERAFDTFQDRLVPELRLAGVTDMISANNYLQN 74
Cdd:NF033594  192 YSDKHSVFrvneeeLAGKGDGLTQFGRALKELGIEIICANSPQAKGRVERANQTLQDRLVKELRLAGISTIEAANEALLP 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937  75 TFIPEYWATTLTVNAKlMRSEHTPVPKYLNIDAICIQKEYRKIRRDHTFSYANAMYQIT-SPLRHSIVSQQVELRKQLDG 153
Cdd:NF033594  272 EFIPDFNRRFAKPPAS-PEDAHRPLPPDEDLDLILCWREERKVSNGLTFSYDNKLYQLEdTPGNRRLIGKKVEVVEYPDG 350
                         170
                  ....*....|.
gi 2793953937 154 GFTAYFADREL 164
Cdd:NF033594  351 RIELRADGRLL 361
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
175-292 1.36e-07

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 52.16  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 175 RKEYGEEVQKKIEAIELANELGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYgQSHNNNRIDEKTRNIVISLTLK 254
Cdd:COG3415    18 RKTKDAREARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRYREGGLAGLKDRP-RGGRPSKLSDEQRERLLELLRE 96
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2793953937 255 S-----PHLTSIRISGEMRKRFNISISHSTVRNIWLEEKLNTR 292
Cdd:COG3415    97 KspdqgSRWTLAELAELLEEEFGVEVSPSTVRRLLKRLGLSYK 139
transpos_IS630 NF033545
IS630 family transposase;
184-289 1.12e-05

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 46.09  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 184 KKIEAIELANELGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYGQSHNNNRIDEKTRNIVISLTLKSP----HLT 259
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEGGLEGLLDKPRPGRPRKLLSEQQAELLALLLEEPPegagHWT 80
                          90       100       110
                  ....*....|....*....|....*....|
gi 2793953937 260 SIRISGEMRKRFNISISHSTVRNIWLEEKL 289
Cdd:NF033545   81 LRELAALLEEEFGVEYSRSTVRRLLKRLGL 110
HTH_29 pfam13551
Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is ...
185-245 4.85e-05

Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433301 [Multi-domain]  Cd Length: 64  Bit Score: 40.43  E-value: 4.85e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2793953937 185 KIEAIELANE-LGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYGQSH-NNNRIDEKTR 245
Cdd:pfam13551   1 RALALLLLAEgVSTVSQAARLLGLSRRTVYRWLKRFNEGGLAALLDRPRSGRpRNNRLDEEQE 63
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
197-299 8.64e-04

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 40.54  E-value: 8.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 197 NVREAARQSGCSVKSIHNNRQLLEAHGPLAL--KRLyGQShNNNRIDEKTRNIVISL----------TLKSPHLtsiris 264
Cdd:NF033594   12 TVKEAAELLGLSERQVRRLLKRYREEGAAGLvhGNR-GRP-PNNRLPDELRERVLALyreryydfgpTLALEKL------ 83
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2793953937 265 gemRKRFNISISHSTVRNIWLEEKL-NTRELREARA 299
Cdd:NF033594   84 ---RERHGISLSRETVRRWMIEAGLwSPRKQRRPKV 116
transpos_IS481 NF033577
IS481 family transposase; null
1-54 3.95e-03

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 38.34  E-value: 3.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2793953937   1 YVDRAGIFggpkRCHFSQMQRACEELGIEIIF--ANSPQGKGRIERAFDTFQDRLV 54
Cdd:NF033577  192 LTDNGSEF----RSRAHGFELALAELGIEHRRtrPYHPQTNGKVERFHRTLKDEFA 243
 
Name Accession Description Interval E-value
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
1-164 1.09e-64

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 207.33  E-value: 1.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937   1 YVDRAGIF------GGPKRCHFSQMQRACEELGIEIIFANSPQGKGRIERAFDTFQDRLVPELRLAGVTDMISANNYLQN 74
Cdd:NF033594  192 YSDKHSVFrvneeeLAGKGDGLTQFGRALKELGIEIICANSPQAKGRVERANQTLQDRLVKELRLAGISTIEAANEALLP 271
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937  75 TFIPEYWATTLTVNAKlMRSEHTPVPKYLNIDAICIQKEYRKIRRDHTFSYANAMYQIT-SPLRHSIVSQQVELRKQLDG 153
Cdd:NF033594  272 EFIPDFNRRFAKPPAS-PEDAHRPLPPDEDLDLILCWREERKVSNGLTFSYDNKLYQLEdTPGNRRLIGKKVEVVEYPDG 350
                         170
                  ....*....|.
gi 2793953937 154 GFTAYFADREL 164
Cdd:NF033594  351 RIELRADGRLL 361
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
175-292 1.36e-07

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 52.16  E-value: 1.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 175 RKEYGEEVQKKIEAIELANELGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYgQSHNNNRIDEKTRNIVISLTLK 254
Cdd:COG3415    18 RKTKDAREARRLRAVLLLAEGLSVREIAERLGVSRSTVYRWLKRYREGGLAGLKDRP-RGGRPSKLSDEQRERLLELLRE 96
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2793953937 255 S-----PHLTSIRISGEMRKRFNISISHSTVRNIWLEEKLNTR 292
Cdd:COG3415    97 KspdqgSRWTLAELAELLEEEFGVEVSPSTVRRLLKRLGLSYK 139
transpos_IS630 NF033545
IS630 family transposase;
184-289 1.12e-05

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 46.09  E-value: 1.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 184 KKIEAIELANELGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYGQSHNNNRIDEKTRNIVISLTLKSP----HLT 259
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKRFNEGGLEGLLDKPRPGRPRKLLSEQQAELLALLLEEPPegagHWT 80
                          90       100       110
                  ....*....|....*....|....*....|
gi 2793953937 260 SIRISGEMRKRFNISISHSTVRNIWLEEKL 289
Cdd:NF033545   81 LRELAALLEEEFGVEYSRSTVRRLLKRLGL 110
HTH_29 pfam13551
Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is ...
185-245 4.85e-05

Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433301 [Multi-domain]  Cd Length: 64  Bit Score: 40.43  E-value: 4.85e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2793953937 185 KIEAIELANE-LGNVREAARQSGCSVKSIHNNRQLLEAHGPLALKRLYGQSH-NNNRIDEKTR 245
Cdd:pfam13551   1 RALALLLLAEgVSTVSQAARLLGLSRRTVYRWLKRFNEGGLAALLDRPRSGRpRNNRLDEEQE 63
HTH_32 pfam13565
Homeodomain-like domain;
239-284 7.29e-05

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 40.36  E-value: 7.29e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2793953937 239 RIDEKTRNIVISLTLKSPHLTSIRISGEMRKRFNISISHSTVRNIW 284
Cdd:pfam13565  28 KLTDEQEARLLALLCEEPRWSPRLLAERLEEEFGVKVSRSTVRRIL 73
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
197-299 8.64e-04

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 40.54  E-value: 8.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2793953937 197 NVREAARQSGCSVKSIHNNRQLLEAHGPLAL--KRLyGQShNNNRIDEKTRNIVISL----------TLKSPHLtsiris 264
Cdd:NF033594   12 TVKEAAELLGLSERQVRRLLKRYREEGAAGLvhGNR-GRP-PNNRLPDELRERVLALyreryydfgpTLALEKL------ 83
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2793953937 265 gemRKRFNISISHSTVRNIWLEEKL-NTRELREARA 299
Cdd:NF033594   84 ---RERHGISLSRETVRRWMIEAGLwSPRKQRRPKV 116
transpos_IS481 NF033577
IS481 family transposase; null
1-54 3.95e-03

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 38.34  E-value: 3.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2793953937   1 YVDRAGIFggpkRCHFSQMQRACEELGIEIIF--ANSPQGKGRIERAFDTFQDRLV 54
Cdd:NF033577  192 LTDNGSEF----RSRAHGFELALAELGIEHRRtrPYHPQTNGKVERFHRTLKDEFA 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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