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Conserved domains on  [gi|2795086571|ref|WP_372524213|]
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tetratricopeptide repeat protein, partial [Sulfuricaulis sp.]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-157 1.13e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 1.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG2956    97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYAR 157
Cdd:COG2956   177 CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALAD 253
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-157 1.13e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 1.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG2956    97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYAR 157
Cdd:COG2956   177 CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALAD 253
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-144 1.70e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 1.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 82-114 8.10e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 32.49  E-value: 8.10e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNPR 114
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 82-113 8.25e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 32.42  E-value: 8.25e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2795086571   82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNP 113
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 88-145 9.86e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 35.56  E-value: 9.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2795086571  88 LAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDT 145
Cdd:PRK11788  186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQ 243
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-157 1.13e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 1.13e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG2956    97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPD 176

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYAR 157
Cdd:COG2956   177 CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALAD 253
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 3-144 4.72e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 4.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   3 LQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSA 82
Cdd:COG2956    65 HQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2795086571  83 DYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG2956   145 HAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-144 1.11e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.71  E-value: 1.11e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   2 HLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGS 81
Cdd:COG3914    66 EAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDF 145

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG3914   146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE 208
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 11-143 1.57e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 1.57e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  11 AQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAE 90
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2795086571  91 LYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAI 143
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 32-158 4.75e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 4.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  32 EAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGNHAEATKAYTEAIKL 111
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2795086571 112 NPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYARQ 158
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEAS 127
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-144 8.88e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.89  E-value: 8.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG2956    29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPD 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG2956   109 DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK 172
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-143 1.47e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.77  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   2 HLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGS 81
Cdd:COG3914    32 LEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDN 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAI 143
Cdd:COG3914   112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
13-144 2.71e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 2.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  13 HPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELY 92
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLAL 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2795086571  93 RRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG0457    87 QALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALE 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1-161 2.82e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 2.82e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG0457    29 EDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPD 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYARQRL 160
Cdd:COG0457   109 DAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAAL 188


                  .
gi 2795086571 161 A 161
Cdd:COG0457   189 A 189
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 1-115 3.29e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.50  E-value: 3.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG4783    25 ALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPE 104

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPRE 115
Cdd:COG4783   105 HPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 25-144 8.14e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 8.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  25 LQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGNHAEATKA 104
Cdd:COG2956    19 LLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEEL 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2795086571 105 YTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG2956    99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 1-112 1.28e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.73  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG2956   165 EALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244

                          90       100       110
                  ....*....|....*....|....*....|..
gi 2795086571  81 SADYMAfLAELYRRAGNHAEATKAYTEAIKLN 112
Cdd:COG2956   245 DDLLLA-LADLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-144 1.70e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 1.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 3-113 2.76e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   3 LQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSA 82
Cdd:COG4235     6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2795086571  83 DYMAFLAELYRRAGNHAEATKAYTEAIKLNP 113
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 14-115 1.58e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 1.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  14 PQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYR 93
Cdd:TIGR02917 465 ASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYL 544

                          90       100
                  ....*....|....*....|..
gi 2795086571  94 RAGNHAEATKAYTEAIKLNPRE 115
Cdd:TIGR02917 545 RTGNEEEAVAWLEKAAELNPQE 566
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 52-144 1.72e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.18  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  52 LLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQD 131
Cdd:COG4783     8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGD 87

                          90
                  ....*....|...
gi 2795086571 132 WKTAGDAYQRAID 144
Cdd:COG4783    88 YDEALALLEKALK 100
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 18-114 1.82e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 1.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  18 ELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGN 97
Cdd:TIGR02917 129 ALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGN 208

                          90
                  ....*....|....*..
gi 2795086571  98 HAEATKAYTEAIKLNPR 114
Cdd:TIGR02917 209 IELALAAYRKAIALRPN 225
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 5-143 3.81e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.75  E-value: 3.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   5 AALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSADY 84
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2795086571  85 MAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAI 143
Cdd:COG3914    81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRAL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 52-153 1.32e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  52 LLLARIQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQD 131
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90       100
                  ....*....|....*....|..
gi 2795086571 132 WKTAGDAYQRAIDTGSLDDNLL 153
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEAL 113
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 2-135 2.01e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 2.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   2 HLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEA-SRQAGAG 80
Cdd:TIGR02917  44 QLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGkTLLDDEG 123

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTA 135
Cdd:TIGR02917 124 AAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEA 178
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
25-114 2.37e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 2.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  25 LQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAgAGSADYMAFLAELYRRAGNHAEATKA 104
Cdd:COG3063     3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLD-PNNAEALLNLAELLLELGDYDEALAY 81

                          90
                  ....*....|
gi 2795086571 105 YTEAIKLNPR 114
Cdd:COG3063    82 LERALELDPS 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
57-144 4.19e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 4.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  57 IQIEHGADQKALAVMEASRQAGAGSADYMAFLAELYRRAGNHAEAtKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAG 136
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                  ....*...
gi 2795086571 137 DAYQRAID 144
Cdd:COG3063    80 AYLERALE 87
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1-115 4.35e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.59  E-value: 4.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG3914   133 AALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPD 212

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2795086571  81 SADYMAFLAELYRRAG--NHAEATKAYTEAIKLNPRE 115
Cdd:COG3914   213 NADAHSNLLFALRQACdwEVYDRFEELLAALARGPSE 249
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
80-144 6.09e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 6.09e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2795086571  80 GSADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG4785   105 DLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALE 169
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-144 6.37e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 6.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAgAG 80
Cdd:TIGR02917 656 TSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR-AP 734

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:TIGR02917 735 SSQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVK 798
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
76-144 1.22e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.97  E-value: 1.22e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2795086571  76 QAGAGSADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALE 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 3-148 1.60e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.25  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   3 LQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSA 82
Cdd:COG5010     9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNP 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2795086571  83 DYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSL 148
Cdd:COG5010    89 ELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 2-135 3.50e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.99  E-value: 3.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   2 HLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGS 81
Cdd:TIGR02917 283 TLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDD 362

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNP-------REGRSWVGMGISLEAAQDWKTA 135
Cdd:TIGR02917 363 PAALSLLGEAYLALGDFEKAAEYLAKATELDPenaaartQLGISKLSQGDPSEAIADLETA 423
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-115 4.30e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.60  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:TIGR02917 146 KSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPN 225

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPRE 115
Cdd:TIGR02917 226 NIAVLLALATILIEAGEFEEAEKHADALLKKAPNS 260
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 79-144 4.34e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 35.55  E-value: 4.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2795086571  79 AGSADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAID 144
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE 66
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 2-118 4.38e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.60  E-value: 4.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   2 HLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGS 81
Cdd:TIGR02917 317 YLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPEN 396

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRS 118
Cdd:TIGR02917 397 AAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRA 433
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-143 5.58e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.60  E-value: 5.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:TIGR02917 486 EAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQ 565

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAI 143
Cdd:TIGR02917 566 EIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL 628
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
1-161 7.96e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 35.75  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   1 KHLQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAG 80
Cdd:COG0457    63 ADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPD 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571  81 SADYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYARQRL 160
Cdd:COG0457   143 DADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAEL 222


                  .
gi 2795086571 161 A 161
Cdd:COG0457   223 L 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-161 7.96e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 35.83  E-value: 7.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2795086571   3 LQAALNFSAQHPQSRELLAGLELQNGRWHEAQQTLEQGIEKVPAHYPFTLLLARIQIEHGADQKALAVMEASRQAGAGSA 82
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2795086571  83 DYMAFLAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDTGSLDDNLLKYARQRLA 161
Cdd:TIGR02917 670 EAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLA 748
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 82-114 8.10e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 32.49  E-value: 8.10e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2795086571  82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNPR 114
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 82-113 8.25e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 32.42  E-value: 8.25e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 2795086571   82 ADYMAFLAELYRRAGNHAEATKAYTEAIKLNP 113
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDP 32
TPR_1 pfam00515
Tetratricopeptide repeat;
88-113 8.75e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 32.39  E-value: 8.75e-03
                          10        20
                  ....*....|....*....|....*.
gi 2795086571  88 LAELYRRAGNHAEATKAYTEAIKLNP 113
Cdd:pfam00515   7 LGNAYFKLGKYDEALEYYEKALELNP 32
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 88-145 9.86e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 35.56  E-value: 9.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2795086571  88 LAELYRRAGNHAEATKAYTEAIKLNPREGRSWVGMGISLEAAQDWKTAGDAYQRAIDT 145
Cdd:PRK11788  186 LAQQALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVEEQ 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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