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Conserved domains on  [gi|2796125641|ref|WP_372879222|]
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TonB-dependent receptor [Spongiibacter marinus]

Protein Classification

TonB-dependent receptor( domain architecture ID 11446927)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0009279|GO:0055085
PubMed:  36944260|35464957
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-809 3.49e-75

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


:

Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 257.83  E-value: 3.49e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  26 LEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIG-TDIYIRGIGSGENqgfeqSVGMY 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGaGQISIRGFGGGGN-----RVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 105 VDGVYYGRA-----QLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDlGERVIDFVAS 179
Cdd:COG1629    76 VDGVPLNDPsggdgGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSY-GTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 180 GPlTDALSMRFAMRQRQIDGFVENQVLDRDeaerdeaTYRLKVGWDPSDDFKamlkleigsFDVVGRQSEIINDTPsdsd 259
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRY-------NLRAKLGYQLGDDTR---------LTLSASYSDSDQDSP---- 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 260 ififtgrtyGEILNNTVFPDFGAASGVFAalpapvrnllqlqdngsilnmqaddsvldtkadrkrhANGDFSYNDTQNVT 339
Cdd:COG1629   214 ---------GYLTLAALRPRGAMDDGTNP-------------------------------------YSNDTDDNTRDRYS 247
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 340 LNMDW--YKDGHTFSSITAYMAYQYDEecDCDFTGSPL---FQVVMEEEYEQFSQEFRWISPA--GENFDMIAGTYFQYN 412
Cdd:COG1629   248 LSLEYehLGDGLKLSASAYYRYDDTDL--DSDFTPTPAdggTLEQTDFDNRTYGLELRLTYDLgfGGKHTLLVGLDYQRQ 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 413 DIyffdsivlpstlvpqlinaadlleggargdidpgaNGSSGFELLGIGdagnSLIDIRSPRDFKSDSIIASAFMQGTWI 492
Cdd:COG1629   326 DL-----------------------------------DGSGYPLDLGSG----SLPTLTSGADDDGTTTSLALYAQDTYK 366
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 493 INPSWRLTLGGRYTYEKKSGsrklefglpdgsrlpigeTDTAAAVTFAAerhdlkGKRTESQFAPLVNIQWDINDAAMSY 572
Cdd:COG1629   367 LTDKLTLTAGLRYDYVSYDV------------------DDTVTGTDSAS------GSRSYSAFSPSLGLTYQLSPNLSLY 422
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 573 FSARRGFKSGGYDARsNSSPSADPTPSNPNavgpnpqvligsfeYEEERATSYELGLKTTLFDGVAELNTALFYTQFDDL 652
Cdd:COG1629   423 ASYSRGFRAPTFGEL-YANGTDPYSVGNPD--------------LKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNE 487
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 653 QVSVFDGT---LGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFqnhefgtciqdqapDNPNGINCDYSGKT 729
Cdd:COG1629   488 ILSVPLPNdsgFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKF--------------DDDTDGSADLDGNR 553
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 730 NQYAADFSGNLLLAYESALGdslmLRANLDAIFSDEYhPSPNLDERVKQDAFIQYNGRVSLSAADGtWELALLGKNLTDE 809
Cdd:COG1629   554 LPGVPPLTANLGLTYEFPGG----WSLGLGVRYVGDR-YLDDANTQGAPGGYTLVDLGAGYRFGDN-LTLSLGVDNLFDK 627
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-809 3.49e-75

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 257.83  E-value: 3.49e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  26 LEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIG-TDIYIRGIGSGENqgfeqSVGMY 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGaGQISIRGFGGGGN-----RVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 105 VDGVYYGRA-----QLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDlGERVIDFVAS 179
Cdd:COG1629    76 VDGVPLNDPsggdgGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSY-GTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 180 GPlTDALSMRFAMRQRQIDGFVENQVLDRDeaerdeaTYRLKVGWDPSDDFKamlkleigsFDVVGRQSEIINDTPsdsd 259
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRY-------NLRAKLGYQLGDDTR---------LTLSASYSDSDQDSP---- 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 260 ififtgrtyGEILNNTVFPDFGAASGVFAalpapvrnllqlqdngsilnmqaddsvldtkadrkrhANGDFSYNDTQNVT 339
Cdd:COG1629   214 ---------GYLTLAALRPRGAMDDGTNP-------------------------------------YSNDTDDNTRDRYS 247
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 340 LNMDW--YKDGHTFSSITAYMAYQYDEecDCDFTGSPL---FQVVMEEEYEQFSQEFRWISPA--GENFDMIAGTYFQYN 412
Cdd:COG1629   248 LSLEYehLGDGLKLSASAYYRYDDTDL--DSDFTPTPAdggTLEQTDFDNRTYGLELRLTYDLgfGGKHTLLVGLDYQRQ 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 413 DIyffdsivlpstlvpqlinaadlleggargdidpgaNGSSGFELLGIGdagnSLIDIRSPRDFKSDSIIASAFMQGTWI 492
Cdd:COG1629   326 DL-----------------------------------DGSGYPLDLGSG----SLPTLTSGADDDGTTTSLALYAQDTYK 366
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 493 INPSWRLTLGGRYTYEKKSGsrklefglpdgsrlpigeTDTAAAVTFAAerhdlkGKRTESQFAPLVNIQWDINDAAMSY 572
Cdd:COG1629   367 LTDKLTLTAGLRYDYVSYDV------------------DDTVTGTDSAS------GSRSYSAFSPSLGLTYQLSPNLSLY 422
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 573 FSARRGFKSGGYDARsNSSPSADPTPSNPNavgpnpqvligsfeYEEERATSYELGLKTTLFDGVAELNTALFYTQFDDL 652
Cdd:COG1629   423 ASYSRGFRAPTFGEL-YANGTDPYSVGNPD--------------LKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNE 487
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 653 QVSVFDGT---LGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFqnhefgtciqdqapDNPNGINCDYSGKT 729
Cdd:COG1629   488 ILSVPLPNdsgFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKF--------------DDDTDGSADLDGNR 553
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 730 NQYAADFSGNLLLAYESALGdslmLRANLDAIFSDEYhPSPNLDERVKQDAFIQYNGRVSLSAADGtWELALLGKNLTDE 809
Cdd:COG1629   554 LPGVPPLTANLGLTYEFPGG----WSLGLGVRYVGDR-YLDDANTQGAPGGYTLVDLGAGYRFGDN-LTLSLGVDNLFDK 627
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
46-849 4.16e-35

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 142.21  E-value: 4.16e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  46 SVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIGT--DIYIRGIGSgenqgfeQSVGMYVDGVYY------GRAQLAR 117
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGgsTISIRGFGP-------DRTLVLVDGLPLassnygRGVDLNT 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 118 APFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTY----EPDLGERVIDFVASGPLTDALSMRFAMR 193
Cdd:cd01347    74 IPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYgsdnSGSSGGGGFDVSGALADDGAFGARLYGA 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 194 QRQIDGFVeNQVLDRDEAERDEATYRLKVGWDPSDDFKamLKLEIGSFDvvgrqseiindtpSDSDIFIFTGRTYGEILN 273
Cdd:cd01347   154 YRDGDGTI-DGDGQADDSDEERYNVAGKLDWRPDDDTR--LTLDAGYQD-------------QDADGPGGTLPANGTGSS 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 274 NTVFPDfgaasgvfaalpaPVRNLLQLQDNGSilnmqaddsvldtkadrkrhangdfSYNDTQNVTLNMDWYKDGHTFSS 353
Cdd:cd01347   218 LGGGPS-------------SNTNGDRDWDYRD-------------------------RYRKRASLGLEHDLNDTGWTLRA 259
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 354 ITAYmayqydeecdcdftgsplfqvvmEEEYEQFSQEFRWISPAGENFDMIAGTYFQYNDIYFFDsivlpstlvpqlina 433
Cdd:cd01347   260 NLSY-----------------------SYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLG--------------- 301
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 434 adlLEGGARGDIDPGangSSGFELLGIGDAgnslidirspRDFKSDSIIASAFMQGTWIINPSWRLTLGGRYTYEKKSGS 513
Cdd:cd01347   302 ---FDAGLNAPFGTG---PVAHTLTLGVEY----------RREELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSK 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 514 rklefglpdgsrlpigetDTAAAVTfaaerhdlKGKRTESQFAPLVNIQWDINDAAMSYFSARRGFKSGG-YDARSNSSP 592
Cdd:cd01347   366 ------------------DTIAGGT--------TAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSlGELYGGGSH 419
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 593 SADPTPSNPNavgPNPqvligsfeyeeERATSYELGLKTTLFDGVAeLNTALFYTQFDDLQVS---VFDGTLGFNVGNAA 669
Cdd:cd01347   420 GGTAAVGNPN---LKP-----------EKSKQYELGLKYDPGDGLT-LSAALFRIDIKNEIVStptNTGLGLVTVYVNGG 484
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 670 SAVTQGIEFDGRIALSENLMLAGGLAFLDFEFqnhefgtciqdqapdnpNGINCDYSGKTNQYAADFSGNLLLAYE-SAL 748
Cdd:cd01347   485 KARIRGVELEASYDLTDGLGLTGSYTYTDTEV-----------------KRTDGATTGNRLPGIPKHTANLGLDYElPDE 547
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 749 GDSLMLRANLDaifSDEYHPSPNLDERVKQDAFiqynGRVSLSAA-DGTWELALLG--KNLTDELIVLYavdtpvakkVI 825
Cdd:cd01347   548 GLTAGGGVRYR---GKQYADTANGNNTVKVPGY----TLVDLSASyQFTKNLTLRLgvNNLFDKDYYTS---------LS 611
                         810       820
                  ....*....|....*....|....
gi 2796125641 826 AGTTSHHGFTNPPRTLALQASYRW 849
Cdd:cd01347   612 VRGSGLYGYYGPGRTYYLSVSYKF 635
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
42-848 2.39e-28

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 121.37  E-value: 2.39e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  42 DVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIGTD---IYIRGIGSGENqgfeqSVGMYVDGVY-YGRAQLAR 117
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQfgnITIRGFGLEVD-----IDNVYLDGVPlLSRGNLAI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 118 APFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDLGER-VIDFvaSGPLTD--ALSMRFAMRQ 194
Cdd:TIGR01783  76 VDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRtAFDL--GGPLGAdgTFRGRLNGAR 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 195 RQIDGFVENQvldrDEAERDEATyrlKVGWDPSDdfKAMLKLEigsfdvvgrqseiindtPSDSDIFIFTGRTYGEILNN 274
Cdd:TIGR01783 154 QDGDSFYDGA----GEETRLGAT---ATDWQLDD--RTLLRLG-----------------AYYQKERDRGGYGGLPASGG 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 275 TVFPDfgaASGVFAALPAPVRNLLQLQDNGSilnmqADDSVLDTKADRKRHANGDFSYNDTQNVTLNMD-WYKDGHTFSS 353
Cdd:TIGR01783 208 TSGRD---LSSDRYLGTSSNRNYDDREYLSY-----GLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASgYSSDGGLFGR 279
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 354 I-----TAYMAYQYDEECDCDFTGSPLFQVVMEEEYEQFSQEFRWISPAGENFDMIAGTYFQyndiyFFDSIVLPSTLVP 428
Cdd:TIGR01783 280 SltvvnVKQDRVQIDAGLDGEFETGPIEHDLLLGVSYGQRTTNRFNNTGYPSDNIYSLTATS-----SARTDIGDSPKDR 354
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 429 QLINAADLLEGGARGDIdpgangssgfellgigdagnslidirsprdfksdsiiasafmqgtwIINPSWRLTLGGRYTYE 508
Cdd:TIGR01783 355 ALSSTTKALNGVALQRI----------------------------------------------LLADKWTLTLGGRYDSV 388
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 509 KksgsrklefglpdgsrlpigeTDTAAAVTFAAerhdlkGKRTESQFAPLVNIQWDINDAAMSYFSARRGFKSGGYdars 588
Cdd:TIGR01783 389 D---------------------VKSNNGVAGST------GKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGY---- 437
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 589 nsspsadptpsnpnavGPNPQVLIGSfEYEEERATSYELGLKTTLFDGVAeLNTALFYTQFDD-LQVSVFDGTLGFNVGN 667
Cdd:TIGR01783 438 ----------------YPKGAGNSGD-ILEPEKGKNYELGVRYDLGDSLL-ATAALFRITKDNqLVQDPVNGTFSVNAGK 499
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 668 aasAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQnhefgtciqdqapdnpNGINCDYSGKTNQYAADFSGNLLLAYEsA 747
Cdd:TIGR01783 500 ---TRNRGVELEARGYLTPGLSLSAGYTYTDAEFT----------------EDTNGDTQGNTVPFVPKHTASLWASYA-P 559
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 748 LGDSLMLRANLDAIFSDEYHPSPnlDERVKQDAFIQYNGRVSL-SAADGTWELALLGKNLTDELIVLYAVDTpvakkvia 826
Cdd:TIGR01783 560 PVGDNGLTLGGGVQYTGKAYVDG--GNTGKVPSYTVVDLSVRYdLTKKKNLTLALNVNNLFDRDYYTSGYRW-------- 629
                         810       820
                  ....*....|....*....|..
gi 2796125641 827 gTTSHHGFTNPPRTLALQASYR 848
Cdd:TIGR01783 630 -GPSAYIYPGAPRTVGLSVSYD 650
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
400-848 3.04e-24

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 107.16  E-value: 3.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 400 NFDMIAGTYFQYNDIYFFDSIVLPSTLVPQLINAADLLEGGARGdidpGANGSSGFELLGIGDAGNSLIDIRSPRDFKSD 479
Cdd:pfam00593  93 DYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLG----VELRTAGLDYRRLDDDAYDPYDPANPSSSSYS 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 480 SI---IASAFMQGTWIINPSWRLTLGGRYTYEKKSGSRKLEFglpdgsrlpigetdtaaavtfaaerhDLKGKRTESQFA 556
Cdd:pfam00593 169 DTttdSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGG--------------------------GDNFSRSYSAFS 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 557 PLVNIQWDINDAAMSYFSARRGFKSGGYDARSNSSPsadpTPSNPNAVGPNPQvligsfeYEEERATSYELGLKttLFDG 636
Cdd:pfam00593 223 PRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGS----GGGGGAVAGGNPD-------LKPETSDNYELGLK--YDDG 289
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 637 VAELNTALFYTQFDDLQVSVFDGT----LGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQNhefgtciqd 712
Cdd:pfam00593 290 RLSLSLALFYIDIKNLITSDPDGPglggTVYTYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDA--------- 360
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 713 qapdnpngiNCDYSGKTNQYAADFSGNLLLAYESALGDslmLRANLDAIFSDEY-HPSPNLDERVKQDAFIQYNGRVSLS 791
Cdd:pfam00593 361 ---------DADDTGNPLPNVPRHTANLGLTYDFPLGG---WGARLGARYVGSGeRRYGDAANTFKTPGYTLVDLSAGYR 428
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2796125641 792 AADGtWELALLGKNLTDELIVLYAVdtpvakkviAGTTSHHGFTNPPRTLALQASYR 848
Cdd:pfam00593 429 LNKN-LTLRLGVNNLFDKYYKRYYS---------SGGGNLGGYPGPGRTFYLGLSYK 475
PRK13483 PRK13483
ligand-gated channel protein;
1-236 1.28e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 71.34  E-value: 1.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   1 MIRKTALYSALSIGLCHSPQLFAAQ-----LEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTM 75
Cdd:PRK13483    3 KYLAQVISALCLLPAVFVTHALAQAapdktMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  76 TESSIGTDIYIRGIGSGENQgfeqsvgMYVDgvyyGRAQLAR----------------APFLDLERVEVLRGPQNILLGK 139
Cdd:PRK13483   83 TGGGDRTDISLRGMGSQYTL-------ILVD----GKRQSSRetrpnsdgpgveqawtPPLAAIERIEVIRGPMSSLYGS 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 140 NSIAGAINVGTASPSQE--PELFIQGTYEPDL---GERVIDFVASGPL-TDALSMrfamrqrQIDGfvenQVLDRDEAE- 212
Cdd:PRK13483  152 DAIGGVINIITRKVPNEwqGEVRLDTTLQENSdsgNVYQANFFVNGPLiKDLLGL-------QLYG----QYTQREEDDi 220
                         250       260       270
                  ....*....|....*....|....*....|
gi 2796125641 213 ------RDEATYRLKVGWDPSDDFKAMLKL 236
Cdd:PRK13483  221 eggyrdKDARSLTAKLALTPNEDHDIMLEV 250
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
26-809 3.49e-75

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 257.83  E-value: 3.49e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  26 LEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIG-TDIYIRGIGSGENqgfeqSVGMY 104
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGaGQISIRGFGGGGN-----RVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 105 VDGVYYGRA-----QLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDlGERVIDFVAS 179
Cdd:COG1629    76 VDGVPLNDPsggdgGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSY-GTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 180 GPlTDALSMRFAMRQRQIDGFVENQVLDRDeaerdeaTYRLKVGWDPSDDFKamlkleigsFDVVGRQSEIINDTPsdsd 259
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRY-------NLRAKLGYQLGDDTR---------LTLSASYSDSDQDSP---- 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 260 ififtgrtyGEILNNTVFPDFGAASGVFAalpapvrnllqlqdngsilnmqaddsvldtkadrkrhANGDFSYNDTQNVT 339
Cdd:COG1629   214 ---------GYLTLAALRPRGAMDDGTNP-------------------------------------YSNDTDDNTRDRYS 247
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 340 LNMDW--YKDGHTFSSITAYMAYQYDEecDCDFTGSPL---FQVVMEEEYEQFSQEFRWISPA--GENFDMIAGTYFQYN 412
Cdd:COG1629   248 LSLEYehLGDGLKLSASAYYRYDDTDL--DSDFTPTPAdggTLEQTDFDNRTYGLELRLTYDLgfGGKHTLLVGLDYQRQ 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 413 DIyffdsivlpstlvpqlinaadlleggargdidpgaNGSSGFELLGIGdagnSLIDIRSPRDFKSDSIIASAFMQGTWI 492
Cdd:COG1629   326 DL-----------------------------------DGSGYPLDLGSG----SLPTLTSGADDDGTTTSLALYAQDTYK 366
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 493 INPSWRLTLGGRYTYEKKSGsrklefglpdgsrlpigeTDTAAAVTFAAerhdlkGKRTESQFAPLVNIQWDINDAAMSY 572
Cdd:COG1629   367 LTDKLTLTAGLRYDYVSYDV------------------DDTVTGTDSAS------GSRSYSAFSPSLGLTYQLSPNLSLY 422
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 573 FSARRGFKSGGYDARsNSSPSADPTPSNPNavgpnpqvligsfeYEEERATSYELGLKTTLFDGVAELNTALFYTQFDDL 652
Cdd:COG1629   423 ASYSRGFRAPTFGEL-YANGTDPYSVGNPD--------------LKPETSTNYELGLRYRLLDGRLSLSLALFYSDVDNE 487
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 653 QVSVFDGT---LGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFqnhefgtciqdqapDNPNGINCDYSGKT 729
Cdd:COG1629   488 ILSVPLPNdsgFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKF--------------DDDTDGSADLDGNR 553
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 730 NQYAADFSGNLLLAYESALGdslmLRANLDAIFSDEYhPSPNLDERVKQDAFIQYNGRVSLSAADGtWELALLGKNLTDE 809
Cdd:COG1629   554 LPGVPPLTANLGLTYEFPGG----WSLGLGVRYVGDR-YLDDANTQGAPGGYTLVDLGAGYRFGDN-LTLSLGVDNLFDK 627
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
23-703 6.29e-51

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 189.30  E-value: 6.29e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  23 AAQLEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESS---IGTDIYIRGIGSGENQgfeq 99
Cdd:COG4771    24 ATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGgrgGSSGISIRGLGGDRVL---- 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 100 svgMYVDGV------YYGRAQLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTY-EPDLGER 172
Cdd:COG4771   100 ---VLIDGVpvnnpaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYgSNGNGTY 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 173 VIDFVASGPlTDALSMRFAMRQRQIDGFVENQVLDR-DEAERDEATYRLKVGWDPSDDFKAMLKLEIGSFDVVGRQSEII 251
Cdd:COG4771   177 SGSLSLGGP-GDKLSFLLSGSYRDRDGYLDYRNGGFvGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLG 255
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 252 NDTPSDSDIFIFTGRTYGeilnntvfpdfgaasgvfaalpapvrnllqlqdngsilnmqaDDSVLDTKADRKRHANGDFS 331
Cdd:COG4771   256 DTEISSDNAGDRDTTTDR------------------------------------------GNYSLRYNGDLGDNLDLSLY 293
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 332 YNDTQNVTLNMDWYKDGHTFSSItaymayqydeecdcdftgsplfqvvmeeEYEQFSQEFRWISPAGENFDMIAGTYFQY 411
Cdd:COG4771   294 YSRTDRDSTNGSLGGSTGSFSDS----------------------------DDTTYGLELDLTYPLGGNHTLTLGAEYRY 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 412 NDIYffdsivlpstlvpqlinaadlleggargdidpgangssgfellgigdagnsliDIRSPRDFKSDSIIASAFMQGTW 491
Cdd:COG4771   346 DDLD-----------------------------------------------------SSSFLGGADASRDTYGLFAQDEW 372
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 492 IINPSWRLTLGGRYtyekksgsrklefglpdgsrlpigetdtaaavtfaaERHDLKGKRTESQFAPLVNIQWDINDAAMS 571
Cdd:COG4771   373 KLTDKLTLTAGLRY------------------------------------DYYSTFGASNYTAFSPRLGLRYDLSDNLTL 416
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 572 YFSARRGFKSGGYDARsnsspsadptpsNPNAVGPNPQVLIGSFEYEEERATSYELGLKTTLFDGVAELNTALFYTQFDD 651
Cdd:COG4771   417 RASYGRGFRAPSLAEL------------YGSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGLSLSLTGFYTDIKD 484
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2796125641 652 LQVSVFDGTLGFNV---GNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQN 703
Cdd:COG4771   485 LIVLVPVGPGPGDVlqyENVGKARTYGLELELKYRLGKGLTLTASYTYLDSKIDD 539
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
35-849 8.79e-44

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 168.52  E-value: 8.79e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  35 LREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVP--NFTMTESSIGTDIYIRGigsgenqgFEQSVGMYVDGVYYGR 112
Cdd:COG4774     1 KTDTPLLDTPQSVTVVTRELIEDQGATSLADALRNVPgvTFGAGEGGNGDSFSIRG--------FSASGDIYVDGLRDPG 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 113 AQlARAPFlDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDlGERVIDFVASGPLTDALSMRFAM 192
Cdd:COG4774    73 QY-RRDTF-NLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGSD-GQRRATLDVNGPLGDDLAYRLNG 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 193 RQRQIDGFvenqvldRDEAERDEATYRLKVGWDPSDDFKAMLkleigsfdvvgrqseiindtpsdsdififtgrtYGEIL 272
Cdd:COG4774   150 MYRDSDSY-------RDGVDNDRWGIAPSLTWRLGDRTRLTL---------------------------------DYEYQ 189
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 273 NNTVFPDFGaasgvfaaLPApvrnllqlQDNGSILNMqaddsvldtkaDRKRHAN--GDFSYNDTQNVTLNMDwykdgHT 350
Cdd:COG4774   190 DDDRTPDYG--------VPA--------VANGRPVDV-----------DRSTFYGqpDDYSDSETDSATLRLE-----HD 237
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 351 FSSitaymayqydeecdcDFTgspLFQVVMeeeYEQFSQEFRWISPAGENFDMIAGTYFQYNDIYFFdsivlpstlvpQL 430
Cdd:COG4774   238 FND---------------NWT---LRNALR---YSDYDRDYRNTYPTGGNATGTVTRSAYRRDQDND-----------TL 285
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 431 INAADLleggaRGDIDPGANGSS---GFELL--------GIGDAGNSLIDIRSP-------------RDFKSDSIIASAF 486
Cdd:COG4774   286 SNQTDL-----TGKFDTGGVKHTllaGVEYSredsdnarYSGGGTAPTVNLYNPvygapvtgptlggADNDSRTDTTGLY 360
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 487 MQGTWIINPSWRLTLGGRYTYEKksgsrklefglpdgsrlpigeTDTAAAVTFAAERHdlkgkRTESQFAPLVNIQWDIN 566
Cdd:COG4774   361 LQDTISLTDRWSLLAGLRYDRFD---------------------TDYTDRTTGATTSS-----YDDSAFSPRAGLVYKPT 414
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 567 DAAMSYFSARRGFK-SGGYDARSNSSPSADPtpsnpnavgpnpqvligsfeyeeERATSYELGLKTTLFDGVAELNTALF 645
Cdd:COG4774   415 PNLSLYASYSTSFNpGGGAPSLSNAGQALDP-----------------------EKSRQYEVGVKWDLLDGRLSLTAALF 471
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 646 YTQFDDLQVSvfDGTLGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQnhefgtciqdqapdnpNGINCDY 725
Cdd:COG4774   472 RIEKTNVRTT--DPANPGVYVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAEIT----------------KSANAAN 533
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 726 SGKTNQYAADFSGNLLLAYESALGDslmLRANLDAIFSDEYHpsPNLDERVKQDAFIQYNGRVSLSAADGtWELALLGKN 805
Cdd:COG4774   534 VGNRLPNVPRHSASLWTTYDLPLPG---LTLGGGVRYVGSRY--ADAANTVKLPSYTRFDAGASYRLNKN-LTLRLNVNN 607
                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....
gi 2796125641 806 LTDElivLYAVdtpvakkviAGTTSHHGFTNPPRTLALQASYRW 849
Cdd:COG4774   608 LTDK---RYYA---------SAYGSGYVTPGAPRTVLLSASYRF 639
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
46-849 4.16e-35

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 142.21  E-value: 4.16e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  46 SVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIGT--DIYIRGIGSgenqgfeQSVGMYVDGVYY------GRAQLAR 117
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGgsTISIRGFGP-------DRTLVLVDGLPLassnygRGVDLNT 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 118 APFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTY----EPDLGERVIDFVASGPLTDALSMRFAMR 193
Cdd:cd01347    74 IPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYgsdnSGSSGGGGFDVSGALADDGAFGARLYGA 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 194 QRQIDGFVeNQVLDRDEAERDEATYRLKVGWDPSDDFKamLKLEIGSFDvvgrqseiindtpSDSDIFIFTGRTYGEILN 273
Cdd:cd01347   154 YRDGDGTI-DGDGQADDSDEERYNVAGKLDWRPDDDTR--LTLDAGYQD-------------QDADGPGGTLPANGTGSS 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 274 NTVFPDfgaasgvfaalpaPVRNLLQLQDNGSilnmqaddsvldtkadrkrhangdfSYNDTQNVTLNMDWYKDGHTFSS 353
Cdd:cd01347   218 LGGGPS-------------SNTNGDRDWDYRD-------------------------RYRKRASLGLEHDLNDTGWTLRA 259
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 354 ITAYmayqydeecdcdftgsplfqvvmEEEYEQFSQEFRWISPAGENFDMIAGTYFQYNDIYFFDsivlpstlvpqlina 433
Cdd:cd01347   260 NLSY-----------------------SYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLG--------------- 301
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 434 adlLEGGARGDIDPGangSSGFELLGIGDAgnslidirspRDFKSDSIIASAFMQGTWIINPSWRLTLGGRYTYEKKSGS 513
Cdd:cd01347   302 ---FDAGLNAPFGTG---PVAHTLTLGVEY----------RREELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSK 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 514 rklefglpdgsrlpigetDTAAAVTfaaerhdlKGKRTESQFAPLVNIQWDINDAAMSYFSARRGFKSGG-YDARSNSSP 592
Cdd:cd01347   366 ------------------DTIAGGT--------TAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSlGELYGGGSH 419
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 593 SADPTPSNPNavgPNPqvligsfeyeeERATSYELGLKTTLFDGVAeLNTALFYTQFDDLQVS---VFDGTLGFNVGNAA 669
Cdd:cd01347   420 GGTAAVGNPN---LKP-----------EKSKQYELGLKYDPGDGLT-LSAALFRIDIKNEIVStptNTGLGLVTVYVNGG 484
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 670 SAVTQGIEFDGRIALSENLMLAGGLAFLDFEFqnhefgtciqdqapdnpNGINCDYSGKTNQYAADFSGNLLLAYE-SAL 748
Cdd:cd01347   485 KARIRGVELEASYDLTDGLGLTGSYTYTDTEV-----------------KRTDGATTGNRLPGIPKHTANLGLDYElPDE 547
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 749 GDSLMLRANLDaifSDEYHPSPNLDERVKQDAFiqynGRVSLSAA-DGTWELALLG--KNLTDELIVLYavdtpvakkVI 825
Cdd:cd01347   548 GLTAGGGVRYR---GKQYADTANGNNTVKVPGY----TLVDLSASyQFTKNLTLRLgvNNLFDKDYYTS---------LS 611
                         810       820
                  ....*....|....*....|....
gi 2796125641 826 AGTTSHHGFTNPPRTLALQASYRW 849
Cdd:cd01347   612 VRGSGLYGYYGPGRTYYLSVSYKF 635
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
23-849 3.79e-30

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 127.32  E-value: 3.79e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  23 AAQLEEVIVTAQLR----------------EQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTM--TESSIGTDI 84
Cdd:COG4773    29 ATTLPEVTVTGTAEgtggytakssstatklDTPLRETPQSVSVVTRQLIEDQGATTLDDALRNVPGVTVssYDGGGRDSF 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  85 YIRGigsgenqgFEQSvGMYVDGVYYGRAQLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQ-- 162
Cdd:COG4773   109 SIRG--------FSID-NYLRDGLPLGGFGGGQPDTANLERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAEPQGEVSls 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 163 -GTYepDLGERVIDFvaSGPLTDA--LSMRFAMRQRQIDGFvenqvldRDEAERDEATYRLKVGWDPSDDfkamLKLEIG 239
Cdd:COG4773   180 aGSW--DTYRATADV--GGPLNEDgtLRYRLNAAYEDGDSF-------RDGVDNRRTLIAPSLDWDLTDD----TTLTLG 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 240 sfdvvgrqseiindtpsdsdififtgrtyGEILNNTVFPDFGaasgvfaALPApvrnllqlqdNGSILNMqaddsvldtk 319
Cdd:COG4773   245 -----------------------------AEYQDDDSTGDRG-------FLPL----------DGTLLDL---------- 268
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 320 aDRKRHANGDFSYNDTQNVTLNMDWykdGHTFSS-ITAYMAYQYDEecdcdftgsplfqvvmEEEYEQFSQEFRWISPAG 398
Cdd:COG4773   269 -PRSTNLGEPWDYYDTETTTLFAEL---EHRFNDdWSLRANARYSD----------------SDRDGRSAYAYGAPDAAT 328
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 399 ENFDMIAGTYFQYNDIYFFDsivlpstlvpqlinaADLleggaRGDIDPGangssGFE---LLGI---------GDAGNS 466
Cdd:COG4773   329 GTLTRYASARDGDSRSDSLD---------------ANL-----NGKFETG-----GLEhtlLVGAdysrydsdsDSATAG 383
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 467 LIDIRSP------------RDFKSDSIIASAFMQGTWIINPSWRLTLGGRYT-YEKKSGSRKlefglpdgsrlpiGETDT 533
Cdd:COG4773   384 TINIYNPvygnlpepdfdaSDTDTTTRQTGLYAQDQISLTDRLSLLLGGRYDwYETDSTNRL-------------GGSTT 450
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 534 AaavtfaaerhdlkgkRTESQFAPLVNIQWDINDAAMSYFSARRGFKSGGYdaRSNSSPSADPtpsnpnavgpnpqvlig 613
Cdd:COG4773   451 S---------------YDDSAFTPRAGLVYDLTPGLSLYASYSESFEPQSG--ADNNGNPLDP----------------- 496
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 614 sfeyeeERATSYELGLKTTLFDGVAELNTALFYTQFDDlqVSVFDGTLGFNVGNAASAVTQGIEFDGRIALSENLMLAGG 693
Cdd:COG4773   497 ------ETGKQYEAGVKGELFDGRLNATLAVFDITQKN--VATTDPDNPNFYVQVGEVRSRGVELELSGELTPGLNLIAG 568
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 694 LAFLDFEFQNhefgtciqdqapDNPNgincdYSGKTNQYAADFSGNLLLAYESALGDSLMLRANLDAIFSDEYhpSPNLD 773
Cdd:COG4773   569 YTYTDAKITK------------DADA-----LEGKRLTNVPRHTASLWTTYRFPSGALKGLGLGGGVRYVGER--YGDAA 629
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796125641 774 ERVKQDAFIQYNGRVSLSAADgTWELALLGKNLTDelivlyavdtpvaKKVIAGTTSHHG-FTNPPRTLALQASYRW 849
Cdd:COG4773   630 NTFTLPSYTLVDAGARYDLGK-NWTLQLNVNNLFD-------------KKYYASSGSRGYvYYGAPRNVRLSLSYKF 692
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
4-849 1.38e-28

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 122.34  E-value: 1.38e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   4 KTALySALSIGLCHSPQLFAAQLEEVIVTA-QLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVP--NF-TMTESS 79
Cdd:COG4772     2 RRAL-AAALLLAAAAAAEAATTLETVVVTGsRAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPgvNVqEEDGFG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  80 IGTDIYIRGIGSGENQGfeqsVGMYVDGVyygraQLARAPFLD-----------LERVEVLRGPQNILLGKNSIAGAINV 148
Cdd:COG4772    81 LRPNIGIRGLGPRRSRG----ITLLEDGI-----PIAPAPYGDpaayyfpdlerMERIEVLRGAAALRYGPQTVGGAINF 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 149 GTASPSQEPELFIQGTYEPDLGERVidFVASGPLTDALSMRFAMRQRQIDGFvenqvldRDEAERDEATYRLKVGWDPSD 228
Cdd:COG4772   152 VTRTIPTAFGGELRVTGGSFGYRRT--HASVGGTVGNFGYLVEYSRKRGDGF-------RDNSGFDINDFNAKLGYRLSD 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 229 DFKamLKLEIGSFDVVgrqseiiNDTP---SDSDififtgrtygeilnntvfpdfgaasgvFAALPapvrnllqLQDNGS 305
Cdd:COG4772   223 RQE--LTLKFQYYDED-------ANTPgglTDAQ---------------------------FDADP--------RQSYRP 258
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 306 ILNMQADDSVLDTKADRKRHANGDFS----YNDTqnvtlNMDWY-----KDGHTFSSITAYMAYQYDeecdcDFTGSPlf 376
Cdd:COG4772   259 ADQFDTRRTQLSLRYEHQLSDNTTLTttayYNDF-----SRNWYirqntADPNTPGLGLRGNPRGYR-----SYGIEP-- 326
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 377 qvvmeeeyeQFSQEFRWispAGENFDMIAGTYFQYNDIYFFdsivlpstlvpQLINAADLLEGGARGDIDpgangssgfe 456
Cdd:COG4772   327 ---------RLTHRFEL---GGVPHTLEVGLRYHREEEDRK-----------QYVNTYGQGRSGAGLRRD---------- 373
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 457 llgigdagnslidirspRDFKSDSIiaSAFMQGTWIINPSWRLTLGGRYTYekksGSRKLefglpdgsrlpigeTDTAAA 536
Cdd:COG4772   374 -----------------RRFSADAL--AAYAQNRFELTGRLTLTPGLRYEH----IRRDR--------------TDRYST 416
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 537 VTFAaerhDLKGKRTESQFAPLVNIQWDINDAAMSYFSARRGFksggydarsnsSPsadPTPSNPNAVGPnpqvliGSFE 616
Cdd:COG4772   417 RTGG----DDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGF-----------EP---PTFGDLAYGNG------GNPD 472
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 617 YEEERATSYELGLKTTLFDGVAeLNTALFYTQFDD--LQVSVFDGTLGFNVgNAASAVTQGIEFDGRIALSE----NLML 690
Cdd:COG4772   473 LKPEKSWNYELGTRGRIGNGLS-AEVALFYIDYDNelGSCSAAGGDRSTFT-NAGETRHQGLELALDYDLLKggglGLPL 550
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 691 AGGLAFLDFEFQNhEFGTciqdqapdnpngincDYSGKTNQYAADFSGNLLLAYESAlgdslMLRANLDAIFSDE-YHPS 769
Cdd:COG4772   551 FAAYTYTDAEFTS-DFGP---------------VFAGNRLPYVPRHQLTAGLGYEHG-----GWTANLNGRYVSEqFTDA 609
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 770 PNLDE---RVKQDAFIQYNGRVSLSAADGtWELALLGKNLTDElivLYAVDTPvakkviagTTSHHGFT-NPPRTLALQA 845
Cdd:COG4772   610 ANTVAdgsFGKIPSYTVLDLSASYDFGKN-LSLFAGVNNLFDK---RYIASRA--------PNYAAGIRpGPPRTVYAGL 677

                  ....
gi 2796125641 846 SYRW 849
Cdd:COG4772   678 RLKF 681
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
42-848 2.39e-28

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 121.37  E-value: 2.39e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  42 DVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIGTD---IYIRGIGSGENqgfeqSVGMYVDGVY-YGRAQLAR 117
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQfgnITIRGFGLEVD-----IDNVYLDGVPlLSRGNLAI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 118 APFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQGTYEPDLGER-VIDFvaSGPLTD--ALSMRFAMRQ 194
Cdd:TIGR01783  76 VDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRtAFDL--GGPLGAdgTFRGRLNGAR 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 195 RQIDGFVENQvldrDEAERDEATyrlKVGWDPSDdfKAMLKLEigsfdvvgrqseiindtPSDSDIFIFTGRTYGEILNN 274
Cdd:TIGR01783 154 QDGDSFYDGA----GEETRLGAT---ATDWQLDD--RTLLRLG-----------------AYYQKERDRGGYGGLPASGG 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 275 TVFPDfgaASGVFAALPAPVRNLLQLQDNGSilnmqADDSVLDTKADRKRHANGDFSYNDTQNVTLNMD-WYKDGHTFSS 353
Cdd:TIGR01783 208 TSGRD---LSSDRYLGTSSNRNYDDREYLSY-----GLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASgYSSDGGLFGR 279
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 354 I-----TAYMAYQYDEECDCDFTGSPLFQVVMEEEYEQFSQEFRWISPAGENFDMIAGTYFQyndiyFFDSIVLPSTLVP 428
Cdd:TIGR01783 280 SltvvnVKQDRVQIDAGLDGEFETGPIEHDLLLGVSYGQRTTNRFNNTGYPSDNIYSLTATS-----SARTDIGDSPKDR 354
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 429 QLINAADLLEGGARGDIdpgangssgfellgigdagnslidirsprdfksdsiiasafmqgtwIINPSWRLTLGGRYTYE 508
Cdd:TIGR01783 355 ALSSTTKALNGVALQRI----------------------------------------------LLADKWTLTLGGRYDSV 388
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 509 KksgsrklefglpdgsrlpigeTDTAAAVTFAAerhdlkGKRTESQFAPLVNIQWDINDAAMSYFSARRGFKSGGYdars 588
Cdd:TIGR01783 389 D---------------------VKSNNGVAGST------GKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGY---- 437
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 589 nsspsadptpsnpnavGPNPQVLIGSfEYEEERATSYELGLKTTLFDGVAeLNTALFYTQFDD-LQVSVFDGTLGFNVGN 667
Cdd:TIGR01783 438 ----------------YPKGAGNSGD-ILEPEKGKNYELGVRYDLGDSLL-ATAALFRITKDNqLVQDPVNGTFSVNAGK 499
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 668 aasAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQnhefgtciqdqapdnpNGINCDYSGKTNQYAADFSGNLLLAYEsA 747
Cdd:TIGR01783 500 ---TRNRGVELEARGYLTPGLSLSAGYTYTDAEFT----------------EDTNGDTQGNTVPFVPKHTASLWASYA-P 559
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 748 LGDSLMLRANLDAIFSDEYHPSPnlDERVKQDAFIQYNGRVSL-SAADGTWELALLGKNLTDELIVLYAVDTpvakkvia 826
Cdd:TIGR01783 560 PVGDNGLTLGGGVQYTGKAYVDG--GNTGKVPSYTVVDLSVRYdLTKKKNLTLALNVNNLFDRDYYTSGYRW-------- 629
                         810       820
                  ....*....|....*....|..
gi 2796125641 827 gTTSHHGFTNPPRTLALQASYR 848
Cdd:TIGR01783 630 -GPSAYIYPGAPRTVGLSVSYD 650
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
400-848 3.04e-24

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 107.16  E-value: 3.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 400 NFDMIAGTYFQYNDIYFFDSIVLPSTLVPQLINAADLLEGGARGdidpGANGSSGFELLGIGDAGNSLIDIRSPRDFKSD 479
Cdd:pfam00593  93 DYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLG----VELRTAGLDYRRLDDDAYDPYDPANPSSSSYS 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 480 SI---IASAFMQGTWIINPSWRLTLGGRYTYEKKSGSRKLEFglpdgsrlpigetdtaaavtfaaerhDLKGKRTESQFA 556
Cdd:pfam00593 169 DTttdSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGG--------------------------GDNFSRSYSAFS 222
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 557 PLVNIQWDINDAAMSYFSARRGFKSGGYDARSNSSPsadpTPSNPNAVGPNPQvligsfeYEEERATSYELGLKttLFDG 636
Cdd:pfam00593 223 PRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGS----GGGGGAVAGGNPD-------LKPETSDNYELGLK--YDDG 289
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 637 VAELNTALFYTQFDDLQVSVFDGT----LGFNVGNAASAVTQGIEFDGRIALSENLMLAGGLAFLDFEFQNhefgtciqd 712
Cdd:pfam00593 290 RLSLSLALFYIDIKNLITSDPDGPglggTVYTYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDA--------- 360
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 713 qapdnpngiNCDYSGKTNQYAADFSGNLLLAYESALGDslmLRANLDAIFSDEY-HPSPNLDERVKQDAFIQYNGRVSLS 791
Cdd:pfam00593 361 ---------DADDTGNPLPNVPRHTANLGLTYDFPLGG---WGARLGARYVGSGeRRYGDAANTFKTPGYTLVDLSAGYR 428
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2796125641 792 AADGtWELALLGKNLTDELIVLYAVdtpvakkviAGTTSHHGFTNPPRTLALQASYR 848
Cdd:pfam00593 429 LNKN-LTLRLGVNNLFDKYYKRYYS---------SGGGNLGGYPGPGRTFYLGLSYK 475
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
29-231 7.14e-22

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 96.48  E-value: 7.14e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  29 VIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESS---IGTDIYIRGIGSgenqgfeQSVGMYV 105
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGgpgSAASISIRGLGS-------NQTLVLI 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 106 DGV-----YYGRAQLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQ---GTYepdlGERVIDFV 177
Cdd:COG4206    74 DGVplndpSLGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSasyGSF----GTRRLSAS 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2796125641 178 ASGPlTDALSMRFAMRQRQIDGFVENQVLDRDEAERDEATYRLKVGWDPSDDFK 231
Cdd:COG4206   150 LSGG-AGKFSYSLSASYRRSDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGS 202
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
39-145 1.46e-16

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 76.15  E-value: 1.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  39 SLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIG--TDIYIRGIGSgenqgfeQSVGMYVDGV-----YYG 111
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGggSSISIRGFGS-------NRVLVLVDGVplnsgGGG 73
                          90       100       110
                  ....*....|....*....|....*....|....
gi 2796125641 112 RAQLARAPFLDLERVEVLRGPQNILLGKNSIAGA 145
Cdd:pfam07715  74 SVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
PRK13483 PRK13483
ligand-gated channel protein;
1-236 1.28e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 71.34  E-value: 1.28e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   1 MIRKTALYSALSIGLCHSPQLFAAQ-----LEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTM 75
Cdd:PRK13483    3 KYLAQVISALCLLPAVFVTHALAQAapdktMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  76 TESSIGTDIYIRGIGSGENQgfeqsvgMYVDgvyyGRAQLAR----------------APFLDLERVEVLRGPQNILLGK 139
Cdd:PRK13483   83 TGGGDRTDISLRGMGSQYTL-------ILVD----GKRQSSRetrpnsdgpgveqawtPPLAAIERIEVIRGPMSSLYGS 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 140 NSIAGAINVGTASPSQE--PELFIQGTYEPDL---GERVIDFVASGPL-TDALSMrfamrqrQIDGfvenQVLDRDEAE- 212
Cdd:PRK13483  152 DAIGGVINIITRKVPNEwqGEVRLDTTLQENSdsgNVYQANFFVNGPLiKDLLGL-------QLYG----QYTQREEDDi 220
                         250       260       270
                  ....*....|....*....|....*....|
gi 2796125641 213 ------RDEATYRLKVGWDPSDDFKAMLKL 236
Cdd:PRK13483  221 eggyrdKDARSLTAKLALTPNEDHDIMLEV 250
PRK13513 PRK13513
ligand-gated channel protein;
3-186 9.61e-11

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 65.56  E-value: 9.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   3 RKTALYSALSI---GLCHSPQLFAAQLEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESS 79
Cdd:PRK13513    9 HKAALVIAAAIssqAYAAEKTNTATPTDTMVVTASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVPGVVVTGGG 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  80 IGTDIYIRGIGSgenqgfeQSVGMYVDGVYY------------GRAQLARAPFLDLERVEVLRGPQNILLGKNSIAGAIN 147
Cdd:PRK13513   89 STSDISIRGMAA-------KYTLILVDGKRVdtrstrpnsdgsGIEQGWLPPLAAIERIEVVRGPMSSLYGSDAMGGVIN 161
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2796125641 148 VGTASPSQE--PELFIQGTYEPDLGERVI---DFVASGPLTDAL 186
Cdd:PRK13513  162 IITRKVQKEwhGSLRADATLQEDSKSGDIfqtNAYASGPLIDGL 205
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
25-258 9.72e-11

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 65.41  E-value: 9.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  25 QLEEVIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTESSIGTDIYIRGIgSGEnqgfeqsvgmY 104
Cdd:PRK13484   29 KEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVEGISITGGNEKPDISIRGL-SGD----------Y 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 105 VDGVYYGRAQLAR---------------APFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEP---ELFIQGTYE 166
Cdd:PRK13484   98 TLILVDGRRQSGResrpngsggfeagfiPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNNQTwdgVLGLGGIIQ 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 167 P--DLGERVI-DFVASGPLT-DALSMRF--AMRQRQIDGFVENQvldrdeAERDEATYRLKVGWDPSDDFKAMLKleigs 240
Cdd:PRK13484  178 EhgKFGNSTTnDFYLSGPLIkDKLGLQLygGMNYRKEDSISQGT------PAKDNKNITATLQFTPTESQKFVFE----- 246
                         250
                  ....*....|....*...
gi 2796125641 241 fdvVGRQSEIINDTPSDS 258
Cdd:PRK13484  247 ---YGKNNQVHTLTPGES 261
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
14-229 1.31e-10

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 64.91  E-value: 1.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  14 GLCHS------PQLFAAQLEE-VIVTAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMT-ESSIGTDIY 85
Cdd:PRK10064   11 GLCASaiscawPVLAVDDDGEtMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTnEGDNRKGVS 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  86 IRGIGSGenqgfeqSVGMYVDG--------VYYGRA-QLARAPFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQE 156
Cdd:PRK10064   91 IRGLDSS-------YTLILIDGkrvnsrnaVFRHNDfDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 157 ------PELFIQgtYEPDLGE-RVIDFVASGPLTD-ALSMRF--AMRQRQIDGFVENQVLDRDEAERDEA-TYR---LKV 222
Cdd:PRK10064  164 whgtvtVDTTIQ--EHRDRGDtYNGQFFTSGPLIDgVLGMKAygSLAKREKDDPQNSTTTDTGETPRIEGfTSRdgnVEF 241

                  ....*..
gi 2796125641 223 GWDPSDD 229
Cdd:PRK10064  242 AWTPNQN 248
PRK14050 PRK14050
TonB-dependent siderophore receptor;
40-157 4.36e-08

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 57.12  E-value: 4.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  40 LQDVPVSVSAIGGEKLMEAGLA-KIEDLQAYVPNftMTESSIGTD-----IYIRGigsgenqgFEQS-VGMYVDGV---Y 109
Cdd:PRK14050   76 ITEIPQSVSVVGRQEMDDRGVTnKVDEALRYTPG--VLSQPFGTDgdtdwFYIRG--------FDATqTGVFLDGLnlfS 145
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2796125641 110 YGRAQLARAPFLdLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEP 157
Cdd:PRK14050  146 YGFGGFQIDPFM-LERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDEP 192
PRK13486 PRK13486
TonB-dependent receptor;
473-691 2.12e-07

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 54.64  E-value: 2.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 473 PRDFKSDSIIASAFMQGTwiINPSWRLTLGGRY----------------TYEKKSGSRKLE--------FGLPDGSRLpi 528
Cdd:PRK13486  332 PRELKESNLILNSLLLTP--LGESHLVTVGGEFqsssmkdgvvlastgeTFRQKSWSVFAEdewhltdaLALTAGSRY-- 407
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 529 getdtaaavtfaaERHDLKGkrteSQFAPLVNIQWDINDAAmsyfsARRGFKSGGYDArsnssPSADPTPSNPNAV-GPN 607
Cdd:PRK13486  408 -------------EHHEQFG----GHFSPRAYLVWDVADAW-----TLKGGVTTGYKA-----PRMGQLHKGISGVsGQG 460
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 608 PQVLIGSFEYEEERATSYELGLkttLFDGVAELNTAL--FYTQFDD--LQVSVFDGTLGFNvgNAASAVTQGIEFDGRIA 683
Cdd:PRK13486  461 KTNLLGNPDLKPEESVSYEAGV---YYDNPAGLNANVtgFMTDFSNkiVSYSINDNTNSYV--NSGKARLHGVEFAGTLP 535

                  ....*....
gi 2796125641 684 L-SENLMLA 691
Cdd:PRK13486  536 LwSEDVTLS 544
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
32-157 6.46e-07

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 53.22  E-value: 6.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  32 TAQLREQSLQDVPVSVSAIGGEKLMEAGLAKIEDLQAYVPNFTMTE--SSIGTD-IYIRGIGSGEnqgfeQSVGMYVDGV 108
Cdd:PRK10044   68 TGTKTDTPIEKTPQSISVVTAEEMALHQPKSVKEALSYTPGVSVGTrgASNTYDhLIIRGFAASG-----QSQNNYLDGL 142
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2796125641 109 -----YYGRAQLAraPFLdLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEP 157
Cdd:PRK10044  143 klqgnFYNDAVID--PYM-LERAELMRGPVSVLYGKSNPGGLLNMVSKRPTTEP 193
PRK13486 PRK13486
TonB-dependent receptor;
24-196 2.63e-05

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 47.71  E-value: 2.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  24 AQLEEV-IVTAQLREQSLQDVPVSVSAIGGEKLMEAglaKIEDLQAYVpnftmtESSIGTDIYIrgiGSGENQGFEQSV- 101
Cdd:PRK13486   22 AAAEDVmIVSASGYEKKLTNAAASVSVISQEELQSS---QYHDLAEAL------RSVEGVDVES---GTGKTGGLEISIr 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641 102 GM-------YVDGVYYGRAQLARA------------PFLDLERVEVLRGPQNILLGKNSIAGAINVGTASPSQEPELFIQ 162
Cdd:PRK13486   90 GMpasytliLIDGVRQGGSSDVTPngfsamntgfmpPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVN 169
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2796125641 163 GTYEPDLGER-----VIDFVASGPLTD---ALSMRFAMRQRQ 196
Cdd:PRK13486  170 AGLNLQESNKwgnssQFNFWSSGPLVDdsvSLQVRGSTQQRQ 211
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
6-153 6.84e-05

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 46.72  E-value: 6.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   6 ALYSALSIGLCHSPQLFAAQ-----LEEVIVTAQLRE-------------QSLQDVPVSVSAIGGEKLMEAGLAKIEDLQ 67
Cdd:PRK09840   16 AFFAGLCIGITPVAQALAAEgqtnaDDTLVVEASTPSlyapdqsadpkfsQPLADTTQTITVISEQVIKDQGATNLTEAL 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  68 AYVP---NFTMTE---SSIGTDIYIRGigsgenqgFEQSVGMYVDGVyygR--AQLARAPFlDLERVEVLRGPQNILLGK 139
Cdd:PRK09840   96 RNVPgvgTFFAGEngnTTTGDAIYMRG--------FDTSNSIYVDGI---RdiGSISRDTF-NTEQVEVIKGPSGTDYGR 163
                         170
                  ....*....|....
gi 2796125641 140 NSIAGAINVGTASP 153
Cdd:PRK09840  164 SAPTGSINMISKQP 177
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
2-189 1.93e-04

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 45.02  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   2 IRKTALYSALSIGLCHSPQLF---------AAQLEEVIVTAQlrEQSLQDVPVSVsaIGGEKLMEAGLAKieDLQAYV-- 70
Cdd:PRK13524    5 IHSLALLVNLGIYGVAQAAEAedaktddtpASHEDTIVVTAA--EQNLQAPGVST--ITAEDIRKRPPAN--DVSEIIrt 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  71 -PNFTMTESSI----GTD--IYIRGIGSgENqgfeqsVGMYVDG--------VYYG-------RAQLARAPFLDLERVEV 128
Cdd:PRK13524   79 mPGVNLTGNSTsgqrGNNrqIDIRGMGP-EN------TLILIDGkpvssrnsVRYGwrgerdtRGDTNWVPPEMIERIEV 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2796125641 129 LRGPQNILLGKNSIAGAINVGTASPSQE-----------PELFIQGtyepdLGERViDFVASGPLTDALSMR 189
Cdd:PRK13524  152 LRGPAAARYGNGAAGGVVNIITKKPTGEwhgswntyfnaPEHKAEG-----ATKRT-NFSLSGPLGDELSFR 217
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
3-189 7.05e-04

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 43.21  E-value: 7.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641   3 RKTALYSALSIGLCHSPQLFAAQLEE---------VIVTAqlrEQSLQDVPvSVSAIGGEKLMEAglAKIEDLQAYV--- 70
Cdd:PRK13528    4 RVNKILWLLTVLLVGLNSPVSAAESSdddngetmvVEATA---EQELKQQP-GVSIITAEDIKKR--PPVNDLSDIIrkm 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796125641  71 PNFTMT-ESSIGT-----DIYIRGIGSgENqgfeqsVGMYVDG--------VYYG-------RAQLARAPFLDLERVEVL 129
Cdd:PRK13528   78 PGVNLTgNSASGTrgnnrQIDIRGMGP-EN------TLILIDGvpvtsrnsVRYSwrgerdtRGDTNWVPPEMVERIEVI 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2796125641 130 RGPQNILLGKNSIAGAINVGTASPSQEPE----LFiqgTYEPDLGE----RVIDFVASGPLT-DALSMR 189
Cdd:PRK13528  151 RGPAAARYGSGAAGGVVNIITKRPTNDWHgslsLY---TNQPESSKegatRRANFSLSGPLAgDALTMR 216
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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