|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
48-478 |
4.19e-151 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 437.72 E-value: 4.19e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 48 LGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEHLAYPAQLAF 127
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 128 KRDIMLQSLEKFQPKGFRNFQLKPTIGmDDPYGYRNKAQFQVRRDADGHVIAGLYKERSHDLVDLKTCSVQMPATMHVMR 207
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPIEDVPTIG-DDPWGYRNKARLSLGRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 208 GVVALMEELDVSTYDEKRGTGLVRTVVVRVAEGTGEVQVVFVTAKAPFPQEAEMVDRLLTEFPEIVSIMQNINNDKTSLI 287
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 288 WGEKTRLLAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGVGTIGLSIAHAAKEVRG 367
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 368 MDVIADAVDDANENARINHIDNVHYETGTAETIIPKWLNEGFKPDALIVDPPRTGLDDGLINAILTAKPKKFVYISCNPS 447
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 2796891846 448 TLARDL-VKLTEQYHVNYIQSVDMMPQTARCE 478
Cdd:TIGR00479 400 TLARDLeALCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
39-484 |
8.79e-148 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 426.90 E-value: 8.79e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 39 QRFPLTIKRLGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEH 118
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 119 LAYPAQLAFKRDIMLQSLEKFQpkGFRNFQLKPTIGMDDPYGYRNKAQFQVRRDaDGHVIAGLYKERSHDLVDLKTCSVQ 198
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIG--GLPEVEVEPIIGSPEPWGYRNRARLSVRRT-DGRLRLGFYARGSHELVDIDECPLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 199 MPATMHVMRGVVALMEELDvstydekRGTGLVRTVVVRvaegtgevqvvfvtakapfpqeaemvdrlltefpeivsimqn 278
Cdd:COG2265 158 DPALNALLPALRELLAELG-------ARRGELRHLVVR------------------------------------------ 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 279 inndktsliwgektrllAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGVGTIGLSI 358
Cdd:COG2265 189 -----------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPL 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 359 AHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPKWLnEGFKPDALIVDPPRTGLDDGLINAILTAKPKK 438
Cdd:COG2265 252 ARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL-WGGRPDVVVLDPPRAGAGPEVLEALAALGPRR 330
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 2796891846 439 FVYISCNPSTLARDLVKLTEQ-YHVNYIQSVDMMPQTARCEAVVKFT 484
Cdd:COG2265 331 IVYVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
39-486 |
2.09e-60 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 204.23 E-value: 2.09e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 39 QRFPLTIKRLGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEH 118
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 119 LAYPAQLAFKRDIMLQSLEKFQpkGFRNFQLKPTIgMDDPYGYRNKAQFQVRRDAD-GHVIAGLYKERSHDLVDLKTCSV 197
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLA--GVEPEEVLPPI-AGPPWGYRRRARLSVRYVPKkGQLLVGFREKNSSDIVDIDQCPV 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 198 QMPAtmhvmrgVVALMEELD--VSTYDEKRGTGLVRtvvvrVAEG-TGEVQVVFVTAkaPFPQEaemvDR-LLTEFPEI- 272
Cdd:PRK13168 171 LVPP-------LSALLPPLRalLSSLSAKRRLGHVE-----LAQGdNGTALVLRHLE--PLSEA----DRaKLRAFAEQh 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 273 -VSIMQNINNDKTSLIWGEKTRLLAgkPQIREvlNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGV 351
Cdd:PRK13168 233 gLQLYLQPKGPDLVHLLGPADAQLS--YYLPE--FGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQPGDRVLDLFCGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 352 GTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPK--WLNEGFkpDALIVDPPRTGLDdGLIN 429
Cdd:PRK13168 309 GNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLDPPRAGAA-EVMQ 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 2796891846 430 AILTAKPKKFVYISCNPSTLARDLVKLTEQ-YHVNYIQSVDMMPQTARCEAVVKFTRA 486
Cdd:PRK13168 386 ALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVESMALFERG 443
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
291-485 |
1.66e-11 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 65.54 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 291 KTRLLAGKPQIREVLN----DLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNEtVIDAYSGVGTIGLSIAHAAKEVR 366
Cdd:pfam05958 149 KQKIVLDQDYVDETLPvagrEFIYRQVENSFTQPNAAVNIKMLEWACDVTQGSKGD-LLELYCGNGNFSLALARNFRKVL 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 367 GMDVIADAVDDANENARINHIDNVHYETGTAETIiPKWLNE-------------GFKPDALIVDPPRTGLDDGLINaiLT 433
Cdd:pfam05958 228 ATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEF-TQAMNGvrefnrlkgidlkSYNCSTIFVDPPRAGLDPETLK--LV 304
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2796891846 434 AKPKKFVYISCNPSTLARDLVKLTEQYHVNYIQSVDMMPQTARCEAVVKFTR 485
Cdd:pfam05958 305 QAYPRILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
343-419 |
2.12e-05 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 43.57 E-value: 2.12e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2796891846 343 TVIDAYSGVGTIGLSIAHA-AKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETiIPKWLNEGFkpDALIVDPP 419
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEE-LPPEADESF--DVIISDPP 75
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
48-478 |
4.19e-151 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 437.72 E-value: 4.19e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 48 LGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEHLAYPAQLAF 127
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 128 KRDIMLQSLEKFQPKGFRNFQLKPTIGmDDPYGYRNKAQFQVRRDADGHVIAGLYKERSHDLVDLKTCSVQMPATMHVMR 207
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPIEDVPTIG-DDPWGYRNKARLSLGRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 208 GVVALMEELDVSTYDEKRGTGLVRTVVVRVAEGTGEVQVVFVTAKAPFPQEAEMVDRLLTEFPEIVSIMQNINNDKTSLI 287
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 288 WGEKTRLLAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGVGTIGLSIAHAAKEVRG 367
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 368 MDVIADAVDDANENARINHIDNVHYETGTAETIIPKWLNEGFKPDALIVDPPRTGLDDGLINAILTAKPKKFVYISCNPS 447
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 2796891846 448 TLARDL-VKLTEQYHVNYIQSVDMMPQTARCE 478
Cdd:TIGR00479 400 TLARDLeALCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
39-484 |
8.79e-148 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 426.90 E-value: 8.79e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 39 QRFPLTIKRLGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEH 118
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 119 LAYPAQLAFKRDIMLQSLEKFQpkGFRNFQLKPTIGMDDPYGYRNKAQFQVRRDaDGHVIAGLYKERSHDLVDLKTCSVQ 198
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIG--GLPEVEVEPIIGSPEPWGYRNRARLSVRRT-DGRLRLGFYARGSHELVDIDECPLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 199 MPATMHVMRGVVALMEELDvstydekRGTGLVRTVVVRvaegtgevqvvfvtakapfpqeaemvdrlltefpeivsimqn 278
Cdd:COG2265 158 DPALNALLPALRELLAELG-------ARRGELRHLVVR------------------------------------------ 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 279 inndktsliwgektrllAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGVGTIGLSI 358
Cdd:COG2265 189 -----------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPL 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 359 AHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPKWLnEGFKPDALIVDPPRTGLDDGLINAILTAKPKK 438
Cdd:COG2265 252 ARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL-WGGRPDVVVLDPPRAGAGPEVLEALAALGPRR 330
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 2796891846 439 FVYISCNPSTLARDLVKLTEQ-YHVNYIQSVDMMPQTARCEAVVKFT 484
Cdd:COG2265 331 IVYVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
39-486 |
2.09e-60 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 204.23 E-value: 2.09e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 39 QRFPLTIKRLGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKIHRLKTPSKDRVKPRDAYAAEVGGFELEH 118
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 119 LAYPAQLAFKRDIMLQSLEKFQpkGFRNFQLKPTIgMDDPYGYRNKAQFQVRRDAD-GHVIAGLYKERSHDLVDLKTCSV 197
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLA--GVEPEEVLPPI-AGPPWGYRRRARLSVRYVPKkGQLLVGFREKNSSDIVDIDQCPV 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 198 QMPAtmhvmrgVVALMEELD--VSTYDEKRGTGLVRtvvvrVAEG-TGEVQVVFVTAkaPFPQEaemvDR-LLTEFPEI- 272
Cdd:PRK13168 171 LVPP-------LSALLPPLRalLSSLSAKRRLGHVE-----LAQGdNGTALVLRHLE--PLSEA----DRaKLRAFAEQh 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 273 -VSIMQNINNDKTSLIWGEKTRLLAgkPQIREvlNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGV 351
Cdd:PRK13168 233 gLQLYLQPKGPDLVHLLGPADAQLS--YYLPE--FGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQPGDRVLDLFCGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 352 GTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPK--WLNEGFkpDALIVDPPRTGLDdGLIN 429
Cdd:PRK13168 309 GNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLDPPRAGAA-EVMQ 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 2796891846 430 AILTAKPKKFVYISCNPSTLARDLVKLTEQ-YHVNYIQSVDMMPQTARCEAVVKFTRA 486
Cdd:PRK13168 386 ALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVESMALFERG 443
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
185-486 |
6.20e-34 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 129.99 E-value: 6.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 185 RSHDLVDLKTCSVQMPATMHVMRGVVALMEELDVSTYDEKRGTGLVRTVVVRVAEGTGEVQVVFVT-AKAPFPQEAEMVD 263
Cdd:PRK03522 17 RDGTPVDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGELKYILLTESQSDGELMLRFVLrSETKLARLRRALP 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 264 RLLTEFPEIVSIMQNINNDKTSLIWGEKTRLLAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEA---LKALALSd 340
Cdd:PRK03522 97 WLQAQLPQLKVISVNIQPVHMAILEGEEEIFLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATArdwVRELPPR- 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 341 neTVIDAYSGVGTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIpkwLNEGFKPDALIVDPPR 420
Cdd:PRK03522 176 --SMWDLFCGVGGFGLHCATPGMQLTGIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA---TAQGEVPDLVLVNPPR 250
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2796891846 421 TGLDDGLINAILTAKPKKFVYISCNPSTLARDLVKLTeQYHVNYIQSVDMMPQTARCEAVVKFTRA 486
Cdd:PRK03522 251 RGIGKELCDYLSQMAPRFILYSSCNAQTMAKDLAHLP-GYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
121-485 |
1.56e-29 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 119.17 E-value: 1.56e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 121 YPAQLAFKRdimlQSLEKFQPKGFRNFQ-LKPTIGMDDpyGYRNKAQFQVRRDADGHVIAGLykERSHDLVDLKTCSVQM 199
Cdd:TIGR02085 20 YSEQLTNKQ----QHLKELLAPNATVVQwLAPVTSAEQ--AFRNKAKMVVSGSVERPILGIL--HRDGTPLDLCDCPLYP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 200 PATMHVMRGVVALMEELDVSTYDEKRGTGLVRTVVVRVAEGTGEVQVVFVT-AKAPFPQEAEMVDRLLTEFPEIVSIMQN 278
Cdd:TIGR02085 92 QSFQPVFAYLKNFIARAGLTPYNVAKKKGELKFILLTESENSGQLMLRFVLrSETKLAQIRRALPWLIEQLPQLEVISVN 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 279 INNDKTSLIWGEKTRLLAGKPQIREVLNDLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNETVIDAYSGVGTIGLSI 358
Cdd:TIGR02085 172 IQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQSFFQTNPKVAAQLYATARQWVREIPVTQMWDLFCGVGGFGLHC 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 359 AHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPkwlNEGFKPDALIVDPPRTGLDDGLINAILTAKPKK 438
Cdd:TIGR02085 252 AGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAALDSAKFAT---AQMSAPELVLVNPPRRGIGKELCDYLSQMAPKF 328
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 2796891846 439 FVYISCNPSTLARDLVKLTeQYHVNYIQSVDMMPQTARCEAVVKFTR 485
Cdd:TIGR02085 329 ILYSSCNAQTMAKDIAELS-GYQIERVQLFDMFPHTSHYEVLTLLVR 374
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
291-485 |
1.66e-11 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 65.54 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 291 KTRLLAGKPQIREVLN----DLQFNLSARAFLQLNPYQTVRLYDEALKALALSDNEtVIDAYSGVGTIGLSIAHAAKEVR 366
Cdd:pfam05958 149 KQKIVLDQDYVDETLPvagrEFIYRQVENSFTQPNAAVNIKMLEWACDVTQGSKGD-LLELYCGNGNFSLALARNFRKVL 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 367 GMDVIADAVDDANENARINHIDNVHYETGTAETIiPKWLNE-------------GFKPDALIVDPPRTGLDDGLINaiLT 433
Cdd:pfam05958 228 ATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEF-TQAMNGvrefnrlkgidlkSYNCSTIFVDPPRAGLDPETLK--LV 304
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2796891846 434 AKPKKFVYISCNPSTLARDLVKLTEQYHVNYIQSVDMMPQTARCEAVVKFTR 485
Cdd:pfam05958 305 QAYPRILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEK 356
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
374-458 |
6.39e-10 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 60.61 E-value: 6.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 374 AVDDANENARINHIDNVHYETGTAETIIPKWLNE------------GFKPDALIVDPPRTGLDDGLINaiLTAKPKKFVY 441
Cdd:PRK05031 240 SVAAAQYNIAANGIDNVQIIRMSAEEFTQAMNGVrefnrlkgidlkSYNFSTIFVDPPRAGLDDETLK--LVQAYERILY 317
|
90
....*....|....*..
gi 2796891846 442 ISCNPSTLARDLVKLTE 458
Cdd:PRK05031 318 ISCNPETLCENLETLSQ 334
|
|
| TRAM |
pfam01938 |
TRAM domain; This small domain has no known function. However it may perform a nucleic acid ... |
34-90 |
3.41e-08 |
|
TRAM domain; This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation).
Pssm-ID: 396497 [Multi-domain] Cd Length: 59 Bit Score: 49.91 E-value: 3.41e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2796891846 34 KVTLGQRFPLTIKRLGINGEGIGYFKR-KLVFVKGALPDEVIVAEVTGIKPSFLTAKI 90
Cdd:pfam01938 1 RRYVGQTQEVLVEGLSSNGEGIGRTDNgKVVFVPGALPGEFVEVKITKVKRNYLRGEL 58
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
333-419 |
8.58e-06 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 46.43 E-value: 8.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 333 LKALALSDNETVIDAYSGVGTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAEtiipkwLNEGFKP- 411
Cdd:PRK14968 16 AENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEVIRSD------LFEPFRGd 89
|
90
....*....|
gi 2796891846 412 --DALIVDPP 419
Cdd:PRK14968 90 kfDVILFNPP 99
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
343-419 |
2.12e-05 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 43.57 E-value: 2.12e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2796891846 343 TVIDAYSGVGTIGLSIAHA-AKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETiIPKWLNEGFkpDALIVDPP 419
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEE-LPPEADESF--DVIISDPP 75
|
|
| COG3269 |
COG3269 |
Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; |
21-90 |
2.38e-05 |
|
Predicted RNA-binding protein, contains TRAM domain [General function prediction only];
Pssm-ID: 442500 [Multi-domain] Cd Length: 129 Bit Score: 43.89 E-value: 2.38e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 21 RRPAHSDHQQTGVKVTLGQRFPLTIKRLGINGEGIGYFKRKLVFVKGALPDEVIVAEVTGIKPSFLTAKI 90
Cdd:COG3269 56 RSVGKPEAQELTPPVEEGEEYEVEIEDIGKKGDGIARVEGFVIFVPGAEVGDRVKVKITKVKRNFAFAEV 125
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
339-406 |
8.00e-05 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 44.85 E-value: 8.00e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 339 SDNETVIDAYSGVGTIGLSIA-HAAKEVRGMDVIADAVDDANENARINHI-DNVHYETGTAETIIPKWLN 406
Cdd:COG2520 179 KPGERVLDMFAGVGPFSIPIAkRSGAKVVAIDINPDAVEYLKENIRLNKVeDRVTPILGDAREVAPELEG 248
|
|
| PrmA |
COG2264 |
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis]; |
331-398 |
4.81e-04 |
|
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441865 [Multi-domain] Cd Length: 284 Bit Score: 42.08 E-value: 4.81e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2796891846 331 EALKALALSDnETVIDaysgVGT---IgLSIAHA---AKEVRGMDVIADAVDDANENARINHI-DNVHYETGTAE 398
Cdd:COG2264 140 EALEKLLKPG-KTVLD----VGCgsgI-LAIAAAklgAKRVLAVDIDPVAVEAARENAELNGVeDRIEVVLGDLL 208
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
337-419 |
8.60e-04 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 40.32 E-value: 8.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 337 ALSDNETVIDAYSGVGTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIipKWLNEGFkpDALIV 416
Cdd:COG1041 23 GAKEGDTVLDPFCGTGTILIEAGLLGRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDL--PLADESV--DAIVT 98
|
...
gi 2796891846 417 DPP 419
Cdd:COG1041 99 DPP 101
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
333-434 |
1.25e-03 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 39.79 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796891846 333 LKALALSDNETVIDAYSGVGTIGLSIAHAAKEVR--GMDVIADAVDDANENARINHIDNVHYETGTAETIIPkwlNEGFk 410
Cdd:COG2813 42 LEHLPEPLGGRVLDLGCGYGVIGLALAKRNPEARvtLVDVNARAVELARANAAANGLENVEVLWSDGLSGVP---DGSF- 117
|
90 100
....*....|....*....|....*..
gi 2796891846 411 pDALIVDPP-RTGL--DDGLINAILTA 434
Cdd:COG2813 118 -DLILSNPPfHAGRavDKEVAHALIAD 143
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
328-400 |
2.46e-03 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 38.44 E-value: 2.46e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2796891846 328 LYDEALKALALSDNETVIDAYSGVGTIGLSIAHAAKEVRGMDVIADAVDDANENARINHIdNVHYETGTAETI 400
Cdd:COG2226 10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDL 81
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
338-409 |
7.55e-03 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 37.01 E-value: 7.55e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2796891846 338 LSDNETVIDAYSGVGTIGLSIAH---AAKEVRGMDVIADAVDDANENARINHIDNVHYETGTAETIIPKWLNEGF 409
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEelgPNAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEELPELLEDDKF 75
|
|
| |
