|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
37-1005 |
0e+00 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 1231.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 37 NFMHTPMSSRRTKNSksflnsMLNESRYLNQSNAGSQFIKYGHTPLAIRRIKCARADIGDVGREAFMEDVESGRLPHFID 116
Cdd:PTZ00111 9 QVLSGRVDSLRPDSQ------VFNPNNTRDESNNETQYTMYGKTPNLVRRIRNARNDIGDLGRETFMDQRDVARLPFLLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 117 SNLEQIKELFNQFFDEFniTNYSDVLDFTDEDRSISEYILLhrdnlkvylaYYGWKMIKFIEtgrqnecrlnntnyEDDd 196
Cdd:PTZ00111 83 NRLEELSERFTNFLKNF--TEFSDVLEFKDEQQSKPEYTEL----------YYLWKLMNFIK--------------ENL- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 197 ennenSEGIRNLEHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIISTKYNSLLalvlegdtrsssSDKYPLSST 276
Cdd:PTZ00111 136 -----RDHSTGYSRILPFEVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELL------------SKHYSDLSL 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 277 KQD--YCRVRFFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCTSKKRIGVNNYEKCNEEVYEHVIQG 354
Cdd:PTZ00111 199 ENNsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEHYEYVIQG 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 355 EVQEPVTCSNCNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETP--------------------QSISIYAYDDLID 414
Cdd:PTZ00111 279 EVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLID 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 415 YTKPGDTVELTGILKASPVRLNPRSRCYNSVHRTYINVIHIKkenkqkmklteqndtaniILKRNEDGTVEENFEKLNEQ 494
Cdd:PTZ00111 359 SVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIHVK------------------VINSTNANQPEKGLKYLGNE 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 495 GNllFTTEVIQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYN---------NKYRSEIHILLC 565
Cdd:PTZ00111 421 ND--FSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNkspdacykvDNFRGIINVLLC 498
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 566 GDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFIS-KDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILH 644
Cdd:PTZ00111 499 GDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLY 578
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 645 EVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCK 724
Cdd:PTZ00111 579 EVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK 658
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 725 NFSYnPEEEEDedqedqeedepnyitqqrarkskgtsrknerenyyndgdndddddisnylNDSNDAQNKRgswaNVNIS 804
Cdd:PTZ00111 659 DFLL-PHMTGS--------------------------------------------------GNDEDTYDRS----NTMHV 683
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 805 YDEYNNsSNKKTSKNyliDSNTLALYIAYCRITCNPIISLESKKIIIEEYIKMR-------------------------C 859
Cdd:PTZ00111 684 EDESLR-SEKDYNKN---DLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRqgnfqtsnldelehaqedddddlyyQ 759
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 860 KEGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATFQSLIDPLSGRIDFDQVNLGQTSQHKKKSDL 939
Cdd:PTZ00111 760 SSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQ 839
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 940 IKDIIMNALVL-------KNMTKDELLTHCHETIMNDPQHTTSMDRKSFEEAFYDLEKSQEITRLCSGLYKKK 1005
Cdd:PTZ00111 840 MYEQVLSVLTRssnqdsnKSLDLNEVLSLCHKTFKDNRDHKDGEIYKLISEVLNKMVQEGTAVRENNSYYLKK 912
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
293-909 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 555.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 293 TPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCtskkrigvnnyEKCNEEVYEHVIQGEVQEPVTCSN--CNNKNT 370
Cdd:smart00350 4 SIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTC-----------EKCGATLGPEIQSGRETEPTVCPPreCQSPTP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 371 FELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVELTGILKASPVRLNPRSRCYNSVHRTYI 450
Cdd:smart00350 73 FSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 451 NVIHIKKENKQKMKLTEqndtaniilkrnedgtveenfeklnEQGNLLFTTEVIQKMEQLSKDPNIYQRLVDSIAPSIYG 530
Cdd:smart00350 153 EANHVRKLDYKRSFEDS-------------------------SFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYG 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 531 REDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFISKDSETK 610
Cdd:smart00350 208 HEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETR 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 611 EYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKNKAVVENI 690
Cdd:smart00350 288 EFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENI 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 691 NLPPSLFSRFDLIYLVIDQANEDEDRKLATvlcknfsynpeeeededqedqeedepnyitqqrarkskgtsrknerenyy 770
Cdd:smart00350 368 DLPAPILSRFDLLFVVLDEVDEERDRELAK-------------------------------------------------- 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 771 ndgdndddddisnylndsndaqnkrgswanvNISYDEYNNSSNKKTSKNYLIDSNTLALYIAYCRITCNPIISLESKKII 850
Cdd:smart00350 398 -------------------------------HVVDLHRYSHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKL 446
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 851 IEEYIKMR----CKEGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATF 909
Cdd:smart00350 447 VKAYVDLRkedsQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
205-944 |
1.13e-175 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 527.83 E-value: 1.13e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 205 IRNLEHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIIstkYNSLLALVLEgdtrssssdkyplsstKQDYCRVR 284
Cdd:COG1241 26 AQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEAL---REIDLEPYDV----------------SLGDAHVR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 285 FFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCTSkkrigvnnyekCNEEVYEHVIQGEVQEPVTCSN 364
Cdd:COG1241 87 ITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPR-----------CGTETYVPQTGEKLQEPHECPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 365 CNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVELTGILKASPVRLNPRSRcynS 444
Cdd:COG1241 156 CGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKS---T 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 445 VHRTYINVIHIKKENKQkmklteqndtaniilkrnedgtveenFEKLNeqgnllFTTEVIQKMEQLSKDPNIYQRLVDSI 524
Cdd:COG1241 233 IFDLYLEANSIEVEEKE--------------------------FEEIE------ITEEDEEKIKELSKDPDIYEKIIASI 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 525 APSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFIS 604
Cdd:COG1241 281 APSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAV 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 605 KDSE-TKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKN 683
Cdd:COG1241 361 RDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPY 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 684 KAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYITQQRARKSKGTSRK 763
Cdd:COG1241 441 EPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELA---------------------------RHILKVHRAGELLEQEI 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 764 NEREnyyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkkTSKNYLIDSNTLALYIAYCRITCNPIIS 843
Cdd:COG1241 494 EEET------------------------------------------------EEVKPEIDPDLLRKYIAYARRNVFPVLT 525
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 844 LESKKIIIEEYIKMRCK--EGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATFQSLIDPLSGRID 921
Cdd:COG1241 526 EEAKDLIEDFYVDMRKKgeDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFD 605
|
730 740
....*....|....*....|...
gi 124513100 922 FDQVNLGQTSQHKKKSDLIKDII 944
Cdd:COG1241 606 IDVIETGTSKSQRDKMKLIKDII 628
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
190-1004 |
2.99e-164 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 498.30 E-value: 2.99e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 190 TNYEDDDENNENSEGIRNL--EHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIIstkynsllalvlegdtRSSS 267
Cdd:NF040949 10 RTFRDSFGNEKYKERIFEMiaMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKAL----------------KEIV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 268 SDKYPLSSTKQDYCRVRFFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCtskkrigvnnyEKCNEEV 347
Cdd:NF040949 74 EEEDPEYAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRC-----------RDCGCEF 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 348 YEHVIQGE----VQEPVTCSNCNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVE 423
Cdd:NF040949 143 EWPEEEEEsyeiVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVT 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 424 LTGILKASPVRLNPRSRcyNSVHRTYINVIHIKKENKQkmklteqndtaniilkrnedgtveenFEKLNeqgnllFTTEV 503
Cdd:NF040949 223 VTGILRIKPDSSLKKGS--RPIFKNYIEANHIEVSQKE--------------------------LEEVE------ITEED 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 504 IQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLS 583
Cdd:NF040949 269 EEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLA 348
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 584 PRGIYTSGKGSSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATL 663
Cdd:NF040949 349 PRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATL 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 664 NARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqee 743
Cdd:NF040949 429 NARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLA------------------------ 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 744 depNYITqqrarkskgtsrknerenyyndgdndddddisnylndsndaqnkrgswaNVNISYDEYNNssnkktsknyLID 823
Cdd:NF040949 485 ---RHIL-------------------------------------------------DVHSGKEKVKP----------EID 502
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 824 SNTLALYIAYCRITCNPIISLESKKIIIEEYIKMRCK----EGTKSPTA-SPRQLEGLVRLSQSLAKMKLKRVVSPEEAN 898
Cdd:NF040949 503 PDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKSskssEDPDSPIPiTARQLEALIRLSEAHAKMRLKDEVTAEDAE 582
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 899 EAVRLMNIATFQSLIDPLSGRIDFDQVNLGQTSQHKKKSDLIKDIImnalvlKNMTKDELLTHCHETIMNDPQHttSMDR 978
Cdd:NF040949 583 RAIRLMLAFLESVGIDVETGKIDIDTIMTGKPKSKREKMSKIVEII------KELEEEEECVKIKELIKEAEKK--GIDE 654
|
810 820
....*....|....*....|....*.
gi 124513100 979 KSFEEAFYDLEKSQEITRLCSGLYKK 1004
Cdd:NF040949 655 EKVEELISDLKRSGEIYEPRPGCYKK 680
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
519-907 |
1.44e-139 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 420.30 E-value: 1.44e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITD-KYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSV 597
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 598 GLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPIN 677
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 678 SRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLcknfsynpeeeededqedqeedepnyitqqrarks 757
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHL----------------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 758 kgtsrknerenyyndgdndddddISNYLNDSNDAQnkrgswanvnisydeynnssnkktsKNYLIDSNTLALYIAYCRIT 837
Cdd:cd17755 206 -----------------------VSLYLEDTPEHI-------------------------QDEVLDVEVLTDYISYAREH 237
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 838 CNPIISLESKKIIIEEYIKMRcKEG---TKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIA 907
Cdd:cd17755 238 IHPKLSEEAAQELVQAYVDMR-KMGsdaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
504-719 |
3.53e-127 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.57 E-value: 3.53e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 504 IQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLS 583
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 584 PRGIYTSGKGSSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATL 663
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 124513100 664 NARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLA 719
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLA 217
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
37-1005 |
0e+00 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 1231.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 37 NFMHTPMSSRRTKNSksflnsMLNESRYLNQSNAGSQFIKYGHTPLAIRRIKCARADIGDVGREAFMEDVESGRLPHFID 116
Cdd:PTZ00111 9 QVLSGRVDSLRPDSQ------VFNPNNTRDESNNETQYTMYGKTPNLVRRIRNARNDIGDLGRETFMDQRDVARLPFLLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 117 SNLEQIKELFNQFFDEFniTNYSDVLDFTDEDRSISEYILLhrdnlkvylaYYGWKMIKFIEtgrqnecrlnntnyEDDd 196
Cdd:PTZ00111 83 NRLEELSERFTNFLKNF--TEFSDVLEFKDEQQSKPEYTEL----------YYLWKLMNFIK--------------ENL- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 197 ennenSEGIRNLEHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIISTKYNSLLalvlegdtrsssSDKYPLSST 276
Cdd:PTZ00111 136 -----RDHSTGYSRILPFEVDLMHVYSFDKVLYKLLVTFPADCIAELDKVLVKLFNELL------------SKHYSDLSL 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 277 KQD--YCRVRFFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCTSKKRIGVNNYEKCNEEVYEHVIQG 354
Cdd:PTZ00111 199 ENNsfFPRARLMNKPVSDCVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCRGQKKIGLNDYQPCTCEHYEYVIQG 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 355 EVQEPVTCSNCNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETP--------------------QSISIYAYDDLID 414
Cdd:PTZ00111 279 EVNEPLLCNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgldnsvdnsglngeiymkdnEVINLNLYDDLID 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 415 YTKPGDTVELTGILKASPVRLNPRSRCYNSVHRTYINVIHIKkenkqkmklteqndtaniILKRNEDGTVEENFEKLNEQ 494
Cdd:PTZ00111 359 SVKTGDRVTVVGILKVTPIRTSTTRRTLKSLYTYFVNVIHVK------------------VINSTNANQPEKGLKYLGNE 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 495 GNllFTTEVIQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYN---------NKYRSEIHILLC 565
Cdd:PTZ00111 421 ND--FSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQLFSGNKNSSDFNkspdacykvDNFRGIINVLLC 498
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 566 GDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFIS-KDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILH 644
Cdd:PTZ00111 499 GDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIKfNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLY 578
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 645 EVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCK 724
Cdd:PTZ00111 579 EVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIAK 658
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 725 NFSYnPEEEEDedqedqeedepnyitqqrarkskgtsrknerenyyndgdndddddisnylNDSNDAQNKRgswaNVNIS 804
Cdd:PTZ00111 659 DFLL-PHMTGS--------------------------------------------------GNDEDTYDRS----NTMHV 683
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 805 YDEYNNsSNKKTSKNyliDSNTLALYIAYCRITCNPIISLESKKIIIEEYIKMR-------------------------C 859
Cdd:PTZ00111 684 EDESLR-SEKDYNKN---DLDMLRMYIKFSKLHCFPKLSDEAKKVITREYVKMRqgnfqtsnldelehaqedddddlyyQ 759
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 860 KEGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATFQSLIDPLSGRIDFDQVNLGQTSQHKKKSDL 939
Cdd:PTZ00111 760 SSGTRMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSSTFQSLVDPTTGKIDFDQLHQGITTNKMQQLNQ 839
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 940 IKDIIMNALVL-------KNMTKDELLTHCHETIMNDPQHTTSMDRKSFEEAFYDLEKSQEITRLCSGLYKKK 1005
Cdd:PTZ00111 840 MYEQVLSVLTRssnqdsnKSLDLNEVLSLCHKTFKDNRDHKDGEIYKLISEVLNKMVQEGTAVRENNSYYLKK 912
|
|
| MCM |
smart00350 |
minichromosome maintenance proteins; |
293-909 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 555.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 293 TPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCtskkrigvnnyEKCNEEVYEHVIQGEVQEPVTCSN--CNNKNT 370
Cdd:smart00350 4 SIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTC-----------EKCGATLGPEIQSGRETEPTVCPPreCQSPTP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 371 FELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVELTGILKASPVRLNPRSRCYNSVHRTYI 450
Cdd:smart00350 73 FSLNHERSTFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPYGFKLNTVKGLPVFATYI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 451 NVIHIKKENKQKMKLTEqndtaniilkrnedgtveenfeklnEQGNLLFTTEVIQKMEQLSKDPNIYQRLVDSIAPSIYG 530
Cdd:smart00350 153 EANHVRKLDYKRSFEDS-------------------------SFSVQSLSDEEEEEIRKLSKDPDIYERLARSLAPSIYG 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 531 REDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFISKDSETK 610
Cdd:smart00350 208 HEDIKKAILLLLFGGVHKNLPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETR 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 611 EYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKNKAVVENI 690
Cdd:smart00350 288 EFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENI 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 691 NLPPSLFSRFDLIYLVIDQANEDEDRKLATvlcknfsynpeeeededqedqeedepnyitqqrarkskgtsrknerenyy 770
Cdd:smart00350 368 DLPAPILSRFDLLFVVLDEVDEERDRELAK-------------------------------------------------- 397
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 771 ndgdndddddisnylndsndaqnkrgswanvNISYDEYNNSSNKKTSKNYLIDSNTLALYIAYCRITCNPIISLESKKII 850
Cdd:smart00350 398 -------------------------------HVVDLHRYSHPEEDEAFEPPLSQEKLRKYIAYAREKIKPKLSEEAADKL 446
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 851 IEEYIKMR----CKEGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATF 909
Cdd:smart00350 447 VKAYVDLRkedsQTESRSSIPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
205-944 |
1.13e-175 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 527.83 E-value: 1.13e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 205 IRNLEHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIIstkYNSLLALVLEgdtrssssdkyplsstKQDYCRVR 284
Cdd:COG1241 26 AQEYPEKRSLVVDYNDLYSFDPDLADDLLENPDEVLEAAEEAL---REIDLEPYDV----------------SLGDAHVR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 285 FFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCTSkkrigvnnyekCNEEVYEHVIQGEVQEPVTCSN 364
Cdd:COG1241 87 ITNLPETVPIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPR-----------CGTETYVPQTGEKLQEPHECPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 365 CNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVELTGILKASPVRLNPRSRcynS 444
Cdd:COG1241 156 CGRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKS---T 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 445 VHRTYINVIHIKKENKQkmklteqndtaniilkrnedgtveenFEKLNeqgnllFTTEVIQKMEQLSKDPNIYQRLVDSI 524
Cdd:COG1241 233 IFDLYLEANSIEVEEKE--------------------------FEEIE------ITEEDEEKIKELSKDPDIYEKIIASI 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 525 APSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGLTAFIS 604
Cdd:COG1241 281 APSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAV 360
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 605 KDSE-TKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKN 683
Cdd:COG1241 361 RDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPY 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 684 KAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYITQQRARKSKGTSRK 763
Cdd:COG1241 441 EPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELA---------------------------RHILKVHRAGELLEQEI 493
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 764 NEREnyyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkkTSKNYLIDSNTLALYIAYCRITCNPIIS 843
Cdd:COG1241 494 EEET------------------------------------------------EEVKPEIDPDLLRKYIAYARRNVFPVLT 525
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 844 LESKKIIIEEYIKMRCK--EGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIATFQSLIDPLSGRID 921
Cdd:COG1241 526 EEAKDLIEDFYVDMRKKgeDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVDPETGKFD 605
|
730 740
....*....|....*....|...
gi 124513100 922 FDQVNLGQTSQHKKKSDLIKDII 944
Cdd:COG1241 606 IDVIETGTSKSQRDKMKLIKDII 628
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
190-1004 |
2.99e-164 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 498.30 E-value: 2.99e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 190 TNYEDDDENNENSEGIRNL--EHIKSFEIDLTHIFFFNKKLYKLIIEYPSDCISEIDKIIstkynsllalvlegdtRSSS 267
Cdd:NF040949 10 RTFRDSFGNEKYKERIFEMiaMRKRSLVVDFNDLYMFDPELADLLIEKPDEVLPAASKAL----------------KEIV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 268 SDKYPLSSTKQDYCRVRFFNKKHKDTPRKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCtskkrigvnnyEKCNEEV 347
Cdd:NF040949 74 EEEDPEYAEEVAKFHVRFRNLPRTVPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRC-----------RDCGCEF 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 348 YEHVIQGE----VQEPVTCSNCNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVE 423
Cdd:NF040949 143 EWPEEEEEsyeiVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVT 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 424 LTGILKASPVRLNPRSRcyNSVHRTYINVIHIKKENKQkmklteqndtaniilkrnedgtveenFEKLNeqgnllFTTEV 503
Cdd:NF040949 223 VTGILRIKPDSSLKKGS--RPIFKNYIEANHIEVSQKE--------------------------LEEVE------ITEED 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 504 IQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLS 583
Cdd:NF040949 269 EEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLA 348
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 584 PRGIYTSGKGSSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATL 663
Cdd:NF040949 349 PRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATL 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 664 NARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqee 743
Cdd:NF040949 429 NARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLA------------------------ 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 744 depNYITqqrarkskgtsrknerenyyndgdndddddisnylndsndaqnkrgswaNVNISYDEYNNssnkktsknyLID 823
Cdd:NF040949 485 ---RHIL-------------------------------------------------DVHSGKEKVKP----------EID 502
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 824 SNTLALYIAYCRITCNPIISLESKKIIIEEYIKMRCK----EGTKSPTA-SPRQLEGLVRLSQSLAKMKLKRVVSPEEAN 898
Cdd:NF040949 503 PDLLKKYIAYARKYVRPKLTEEAKKLIEDFYVEMRKSskssEDPDSPIPiTARQLEALIRLSEAHAKMRLKDEVTAEDAE 582
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 899 EAVRLMNIATFQSLIDPLSGRIDFDQVNLGQTSQHKKKSDLIKDIImnalvlKNMTKDELLTHCHETIMNDPQHttSMDR 978
Cdd:NF040949 583 RAIRLMLAFLESVGIDVETGKIDIDTIMTGKPKSKREKMSKIVEII------KELEEEEECVKIKELIKEAEKK--GIDE 654
|
810 820
....*....|....*....|....*.
gi 124513100 979 KSFEEAFYDLEKSQEITRLCSGLYKK 1004
Cdd:NF040949 655 EKVEELISDLKRSGEIYEPRPGCYKK 680
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
519-907 |
1.44e-139 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 420.30 E-value: 1.44e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITD-KYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSV 597
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 598 GLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPIN 677
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 678 SRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLcknfsynpeeeededqedqeedepnyitqqrarks 757
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHL----------------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 758 kgtsrknerenyyndgdndddddISNYLNDSNDAQnkrgswanvnisydeynnssnkktsKNYLIDSNTLALYIAYCRIT 837
Cdd:cd17755 206 -----------------------VSLYLEDTPEHI-------------------------QDEVLDVEVLTDYISYAREH 237
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 838 CNPIISLESKKIIIEEYIKMRcKEG---TKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIA 907
Cdd:cd17755 238 IHPKLSEEAAQELVQAYVDMR-KMGsdaRKRITATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
504-719 |
3.53e-127 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 384.57 E-value: 3.53e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 504 IQKMEQLSKDPNIYQRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLS 583
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 584 PRGIYTSGKGSSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATL 663
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 124513100 664 NARTSILASANPINSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLA 719
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLA 217
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
519-904 |
4.40e-120 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 369.75 E-value: 4.40e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVG 598
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 599 LTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINS 678
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 679 RYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYITQQRARKSK 758
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELA---------------------------EHIIDLHRGSDP 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 759 GTSRKNERENYyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkktsknyLIDSNTLALYIAYCRiTC 838
Cdd:cd17706 214 EEQVKPEEDGI---------------------------------------------------PIDIELLRKYILYAR-QI 241
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124513100 839 NPIISLESKKIIIEEYIKMRcKEGTKSPT--ASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLM 904
Cdd:cd17706 242 HPKISEEAREKLVRWYVELR-KESERRSTipITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLV 308
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
519-907 |
5.78e-110 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 342.85 E-value: 5.78e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITdKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVG 598
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 599 LTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINS 678
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 679 RYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYITqqrarksk 758
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLA---------------------------EHVT-------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 759 gtsrknerenyyndgdndddddisnYLNDSNDAQNkrgswanvnisydeynnssnkktSKNYLIDSNTLALYIAYCRiTC 838
Cdd:cd17758 205 -------------------------YVHQHNKQPD-----------------------SDFEPLDPKLLRAYIALAK-RK 235
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124513100 839 NPIISLESKKIIIEEYIKMRCKEGTKSPTA--SPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIA 907
Cdd:cd17758 236 RPTVPPALADYIVQAYVEMRQEAKRSKDFTftTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
518-904 |
7.29e-107 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 334.80 E-value: 7.29e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 518 QRLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSV 597
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 598 GLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPIN 677
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 678 SRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYITQQRarkS 757
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLA---------------------------NHILDTH---S 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 758 KGTSRKNEREnyyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkktsknylIDSNTLALYIAYCRIT 837
Cdd:cd17761 211 GGEMREIKPE------------------------------------------------------IDPDLLRKYIAYARKN 236
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124513100 838 CNPIISLESKKIIIEEYIKMRCK-EGTKSPTA-SPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLM 904
Cdd:cd17761 237 VRPVLTEEAKQLIKDFYVEMRKSgQETPSPVPiTARQLEALVRLSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
519-905 |
7.95e-107 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 334.72 E-value: 7.95e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVG 598
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 599 LTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINS 678
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 679 RYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCknfsynpeeeededqedqeedepnyitqqrarksk 758
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIV----------------------------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 759 gtsrknerenyyndgdndddddisnylndsndaqnkrgswanvnisydeyNNSSNKKTSKNYLIDSNTLALYIAYCRiTC 838
Cdd:cd17757 206 --------------------------------------------------DLHSKREEAIEPPFTAEQLKRYIAYAR-TF 234
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124513100 839 NPIISLESKKIIIEEYIKMRCKEGTKSPTAS----PRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMN 905
Cdd:cd17757 235 KPKLTKEAKDELVEQYKELRQDDASGSTRSSyritVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLK 305
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
519-903 |
4.03e-103 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 325.11 E-value: 4.03e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSK--ITDKYnnKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSS 596
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRkrLPDGM--RLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 597 VGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPI 676
Cdd:cd17756 79 AGLTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 677 NSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLAtvlcknfsynpeeeededqedqeedepNYI--TQQRA 754
Cdd:cd17756 159 FGRYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIA---------------------------KHVinIHASA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 755 RKSKGTSRKNerenyyndgdndddddisnylndsndaqnkrgswanvnisyDEynnssnkktsknylIDSNTLALYIAYC 834
Cdd:cd17756 212 RKASQSQENE-----------------------------------------GE--------------IPISKLKRYIAYC 236
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124513100 835 RITCNPIISLESKKIIIEEYIKMRCK-----EGTKSPTASP---RQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRL 903
Cdd:cd17756 237 RAKCAPRLSEEAAEKLSNHYVTIRKDvrqneLESDNRSSIPitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRL 313
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
519-904 |
4.89e-94 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 301.29 E-value: 4.89e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVG 598
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 599 LTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINS 678
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 679 RYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCKNFSynpeeeededqedqeedepnyitqqrarKSK 758
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHV----------------------------RSH 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 759 GTSRKNErenyyndgdndddddisnylnDSNDAQNKRGSwanvnisydeynnssnKKTSKNYLIDSNTLALYIAYCRITC 838
Cdd:cd17753 213 PENDEDR---------------------EGEEEKNQRQR----------------PKETKVEPIPQELLRKYIHYAREKV 255
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124513100 839 NPIISLESKKIIIEEYIKMR-CKEGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLM 904
Cdd:cd17753 256 RPKLNQMDMDKVSRVYADLRkESMATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIRVM 322
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
520-907 |
5.21e-92 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 294.76 E-value: 5.21e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 520 LVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGL 599
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 600 TAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSR 679
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 680 YDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCKNFSYNPEEeededqedqeedepnyitqqraRKskg 759
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRYIKFL----------------------RK--- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 760 tsrknerenyyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkktsknylidsntlalYIAYCRITCN 839
Cdd:cd17754 217 ----------------------------------------------------------------------YIHYAKERIK 226
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124513100 840 PIISLESKKIIIEEYIKMRCKEGTKSPTA--SP---RQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMNIA 907
Cdd:cd17754 227 PKLTQEAAEYIAEEYADLRNDDNTKTDKArtSPitaRTLETLIRLATAHAKARLSKTVDKVDAEVALNLLRFA 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
519-904 |
5.28e-74 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 245.91 E-value: 5.28e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 519 RLVDSIAPSIYGREDIKKGLLCQLFGGSK--ITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSS 596
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQkyADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 597 VGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMDDSARAILhEVMEQQTVTIAKAGIVATLNARTSILASANPI 676
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGSQHQALL-EAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 677 NSRYDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATvlcknfsynpeeeededqedqeedepnyiTQQRARK 756
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSE-----------------------------HHQLLRK 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 757 skgtsrknerenyyndgdndddddisnylndsndaqnkrgswanvnisydeynnssnkktsknylidsntlalYIAYCRI 836
Cdd:cd17759 211 -------------------------------------------------------------------------YISYARQ 217
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124513100 837 TCNPIISLESKKIIIEEYIKMRCK-EGTKSPTASPRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLM 904
Cdd:cd17759 218 YVNPVLSKDASEALQEFYLELRKQnQLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIM 286
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
520-725 |
4.29e-64 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 218.95 E-value: 4.29e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 520 LVDSIAPSIYGREDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLCGDPSTAKSQLLHYVHKLSPRGIYTSGKGSSSVGL 599
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 600 TAFISKDSetKEYILESGAVVLSDKGICCIDEFDKMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPiNSR 679
Cdd:cd17760 82 TVTAVKDG--GEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 124513100 680 YDKNKAVVENINLPPSLFSRFDLIYLVIDQANEDEDRKLATVLCKN 725
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFILEN 204
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
295-432 |
8.74e-37 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 134.53 E-value: 8.74e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 295 RKLGPNQIETLVCVKGVIIRCSNIIPEMTMAAFKCtskkrigvnnyEKCNeevyeHVIQGEVQEPVTCSN--CNNKNTFE 372
Cdd:pfam17207 3 RDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTC-----------RKCG-----HTVGVKITEPTKCPNpeCGNKDPFK 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 373 LWHNNCCFSSKQLIKLSEVTEHLKQGETPQSISIYAYDDLIDYTKPGDTVELTGILKASP 432
Cdd:pfam17207 67 LVHEKSKFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
825-905 |
4.55e-23 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 94.15 E-value: 4.55e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 825 NTLALYIAYCRITCNPIISLESKKIIIEEYIKMRcKEGTKSPTASP---RQLEGLVRLSQSLAKMKLKRVVSPEEANEAV 901
Cdd:pfam17855 1 ELLRKYIAYAREKIKPKLSEEAREKLVDAYVELR-KESTGSGSSIPitvRQLESLIRLSEAHAKMRLSEIVTEEDVEEAI 79
|
....
gi 124513100 902 RLMN 905
Cdd:pfam17855 80 RLLK 83
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
561-700 |
3.31e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 47.67 E-value: 3.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 561 HILLCGDPSTAKSQL-LHYVHKLSPRGIYTsgkgsssVGLTAFISKDSETKEYILESGAVVLSD---------KGICCID 630
Cdd:pfam07728 1 GVLLVGPPGTGKTELaERLAAALSNRPVFY-------VQLTRDTTEEDLFGRRNIDPGGASWVDgplvraareGEIAVLD 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124513100 631 EFDKMDDSARAILHEVMEQQTVTIAKAG-IVATLNARTSILASANPINSRYDKnkavveninLPPSLFSRF 700
Cdd:pfam07728 74 EINRANPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
561-703 |
5.20e-04 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 41.36 E-value: 5.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124513100 561 HILLCGDPSTAKSQLLHYVHKLSPRG----IYTSGkgsSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFDKMD 636
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLNA---SDLLEGLVVAELFGHFLVRLLFELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124513100 637 DSARAILHEVMEQQTVTIAKagivatlNARTSILASANPINSrydknkavvenINLPPSLFSRFDLI 703
Cdd:cd00009 98 RGAQNALLRVLETLNDLRID-------RENVRVIGATNRPLL-----------GDLDRALYDRLDIR 146
|
|
| |
