|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
1-1045 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 1746.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 1 MKTEEYQLSGAQAFFKKSLESPMPQSYCPKDVESDWDNLWCSCGFFSPnFERAKTLSQEEKFVMALPPPNVTGCLHIGHT 80
Cdd:PTZ00419 2 MKKEEIKLSKDEKKNKKRNISSMAASYDPKEVESGWYEWWEKSGFFKP-AEDAKSLNSGKKFVIVLPPPNVTGYLHIGHA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 81 LTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERILLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLG 160
Cdd:PTZ00419 81 LTGAIQDSLIRYHRMKGDETLWVPGTDHAGIATQVVVEKKLMKEENKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 161 CSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQKPTRLRIPGYDKTVEVGIL 240
Cdd:PTZ00419 161 SSLDWSREVFTMDEQRSKAVKEAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEIEKPTKITIPGYDKKVEVGVL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 241 WYFSYPLQQKGQqyswhfepenlskiPKITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPFLPERKIRIITDE-Y 319
Cdd:PTZ00419 241 WHFAYPLEDSGQ--------------EEIVVATTRIETMLGDVAVAVHPKDERYKKLHGKELIHPFIPDRKIPIIADDeL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 320 VDPEFGTGCVKITPAHDKNDFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNL 399
Cdd:PTZ00419 307 VDMEFGTGAVKITPAHDPNDYEIAKRHN-----------LPFINIFTLDGKINENGGEFAGMHRFDCRRKIEEELKEMGL 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 400 LVDKTPNtkSMQLPICSRSDDIVELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWW 479
Cdd:PTZ00419 376 LRDKVPN--PMRLPRCSRSGDIVEPMLIPQWYVNCKDMAKRAVEAVRNGELKIIPSSHENVWYHWLENIQDWCISRQLWW 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 480 GHRIPAYRVCMENINAEKKPQDIWVAADSEEEAIKEVINKFQLKLGEFTVERDTDVLDTWFSSGLIPFSSLGWPYKlnpr 559
Cdd:PTZ00419 454 GHRIPAYRVISKGPETDPSDEEPWVVARSEEEALEKAKKKFGLSEEDFELEQDEDVLDTWFSSGLFPFSTLGWPDQ---- 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 560 tgKDDLSTFFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEGISLED 639
Cdd:PTZ00419 530 --TDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFKTVFLHAMVRDSQGEKMSKSKGNVIDPLEVIEGISLQD 607
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 640 LNSKVKKGNLPTSEIKRSIESNSKDFPTGIPECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNI 719
Cdd:PTZ00419 608 LNQKLYEGNLPEKEIKRAIELQKKEFPNGIPECGTDALRFGLLAYTQQGRNINLDINRVVGYRHFCNKLWNAVKFALMKL 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 720 EKLKVYSESTKFQAlslnnileNYYSYLMWEDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKL 799
Cdd:PTZ00419 688 LKDFNLPNSTLFKP--------NNVESLPWEDKWILHRLNVAIKEVTEGFKEYDFSEATQATYNFWLYELCDVYLELIKP 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 800 RFKELNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRLYQlvsSPERFLSISIAKFPTTLKHSQlNYKKDLEYK 879
Cdd:PTZ00419 760 RLSKQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRLPN---YLRKSESISIAKYPQPNPGWN-NEALDEEMK 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 880 IMMRIVSQIRSLTSIMEIPNKEKLSITVYiiykGQDCDTIQLLETVaESFITKLANIGStVTVINPdIKKVNELKSQCLL 959
Cdd:PTZ00419 836 IIMSIVKSIRSLIATLGIPNKTKPDCYVT----AKDAELIELIESA-ENLISTLAKIGS-VSVIPP-IEEEAEVPKGCGF 908
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 960 DIVDDKIDIYLTVPQKVDLSQALQKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESVKLLNEEKINQLIATIASLEIAKE 1038
Cdd:PTZ00419 909 DVVDNKVIIYLNLDEFIDLKKELAKLEKKLAKLQKSLESYLKKISIPNYeDKVPEDVRKLNDEKIDELNEEIKQLEQAIE 988
|
....*..
gi 209876528 1039 NVESLLK 1045
Cdd:PTZ00419 989 ELKSLLK 995
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
23-1034 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1051.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 23 MPQSYCPKDVESDWDNLWCSCGFFSPNFERAKtlsqeEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLW 102
Cdd:COG0525 3 LPKTYDPKEVEAKWYQYWEENGYFKADPDSDK-----EPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 103 IPGTDHAGIATQTVVERiLLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQ 182
Cdd:COG0525 78 QPGTDHAGIATQAVVER-QLAEEGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVRE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 183 AFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQkptrlripgydktvevGILWYFSYPLQQkGQQYswhfepen 262
Cdd:COG0525 157 VFVRLYEKGLIYRGKRLVNWDPKLKTALSDLEVEHEEVK----------------GHLWHIRYPLAD-GSGY-------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 263 lskipkITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPfLPERKIRIITDEYVDPEFGTGCVKITPAHDKNDFDV 342
Cdd:COG0525 212 ------IVVATTRPETMLGDTAVAVHPEDERYKHLIGKTVILP-LVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEV 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 343 ATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDKTPNTksMQLPICSRSDDIV 422
Cdd:COG0525 285 GKRHN-----------LPMINILDEDGTINENAGKYRGLDRFEARKAIVADLEELGLLVKVEPHK--HSVGHSDRSGTVI 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 423 ELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAYrVCMENinaekkpqDI 502
Cdd:COG0525 352 EPYLSDQWFVKMKPLAKPAIEAVEDGEIKFVPERWEKTYFHWMENIRDWCISRQLWWGHRIPAW-YCPDG--------EV 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 503 WVAADsEEEAIKevinkfqlKLGEFTVERDTDVLDTWFSSGLIPFSSLGWPYKlnprtgKDDLSTFFPTTLLETGSDILF 582
Cdd:COG0525 423 YVART-EPEACA--------KAGSVNLTQDEDVLDTWFSSALWPFSTLGWPEK------TEDLKYFYPTSVLVTGFDIIF 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 583 FWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesns 662
Cdd:COG0525 488 FWVARMIMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID----------------------------- 538
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 663 kdfptgipECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKfQALSLnnilen 742
Cdd:COG0525 539 --------KYGADALRFTLAALASPGRDIKFDEERVEGYRNFANKLWNASRFVLMNLEGFDPGLDPDP-EELSL------ 603
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 743 yysylmwEDFFIIHRLNECITKVSASFKEYLFAEVVAATYNF-WlYELCDIYLELTKLRFKElNNSKSAFVAAQVLCTCI 821
Cdd:COG0525 604 -------ADRWILSRLNKTIAEVTEALEKYRFDEAAQALYDFvW-NEFCDWYLELAKPRLYG-GDEAAKRETRATLVYVL 674
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 822 DFGLRLLHPMIPFVTEELYQRLYQLVSSPerflSISIAKFPtTLKHSQLNYKKDLEYKIMMRIVSQIRSLTSIMEIPNKE 901
Cdd:COG0525 675 EQILRLLHPFMPFITEEIWQKLPPRKEGE----SIMLAPWP-EADEELIDEEAEAEFEWLKEVISAIRNIRAEMNIPPSK 749
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 902 KLSITVyiiyKGQDCDTIQLLETvAESFITKLANIgSTVTVInpdikkVNELKSQCLLDIVDDkIDIYLTVPQKVDLSQA 981
Cdd:COG0525 750 KLPLLL----KGADEADRARLEE-NAAYIKRLARL-EEITIL------VDEKPEGAASAVVGG-AEVFLPLEGLIDVEAE 816
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 209876528 982 LQKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESV------KLLN-EEKINQLIATIASLE 1034
Cdd:COG0525 817 RARLEKELAKLEKEIARVEKKLSNEGFvAKAPAEVvekereKLAEaEAKLEKLEEQLARLK 877
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
23-1034 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1028.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 23 MPQSYCPKDVESDWDNLWCSCGFFSPNFERAKTlsqeekFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLW 102
Cdd:PRK05729 5 LPKTYDPKEVEAKWYQKWEEKGYFKPDDNSKKP------FSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLW 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 103 IPGTDHAGIATQTVVERILLKsENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQ 182
Cdd:PRK05729 79 LPGTDHAGIATQMVVERQLAA-EGKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVRE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 183 AFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQkptrlripgydktvevGILWYFSYPLQQkGQQYswhfepen 262
Cdd:PRK05729 158 VFVRLYEKGLIYRGKRLVNWDPKLQTALSDLEVEYKEVK----------------GKLWHIRYPLAD-GSDY-------- 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 263 lskipkITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPfLPERKIRIITDEYVDPEFGTGCVKITPAHDKNDFDV 342
Cdd:PRK05729 213 ------LVVATTRPETMLGDTAVAVNPEDERYKHLIGKTVILP-LVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFEV 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 343 ATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDKTPNTksMQLPICSRSDDIV 422
Cdd:PRK05729 286 GKRHN-----------LPMINIMDEDGTINENPGEYQGLDRFEARKAIVADLEELGLLVKIEPHT--HSVGHSDRSGVVI 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 423 ELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAYrvcmeninaeKKPQDI 502
Cdd:PRK05729 353 EPYLSDQWFVKMKPLAKPALEAVENGEIKFVPERWEKTYFHWMENIQDWCISRQLWWGHRIPAW----------YDEDGE 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 503 WVAADSEEEAIKEVInkfqlklgeftVERDTDVLDTWFSSGLIPFSSLGWPYKlnprtgKDDLSTFFPTTLLETGSDILF 582
Cdd:PRK05729 423 VYVGREEPEAREKAL-----------LTQDEDVLDTWFSSALWPFSTLGWPEK------TEDLKRFYPTSVLVTGFDIIF 485
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 583 FWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesns 662
Cdd:PRK05729 486 FWVARMIMMGLHFTGQVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLDLID----------------------------- 536
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 663 kdfptgipECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKfQALSLnnilen 742
Cdd:PRK05729 537 --------KYGADALRFTLAALASPGRDIRFDEERVEGYRNFANKLWNASRFVLMNLEGADVGELPDP-EELSL------ 601
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 743 yysylmwEDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNNSKSAFVAAQVLCTCid 822
Cdd:PRK05729 602 -------ADRWILSRLNRTVAEVTEALDKYRFDEAARALYEFIWNEFCDWYLELAKPVLQEAAKRATRATLAYVLEQI-- 672
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 823 fgLRLLHPMIPFVTEELYQRLYQLvsspERFLSISIAKFPTtlKHSQLNYKKDLEYKIMMRIVSQIRSLTSIMEIPNKEK 902
Cdd:PRK05729 673 --LRLLHPFMPFITEELWQKLAPL----GIEESIMLAPWPE--ADEAIDEAAEAEFEWLKELITAIRNIRAEMNIPPSKK 744
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 903 LSITVyiiyKGQDCDTIQLLETvAESFITKLANIgSTVTVinpdIKKVNELKSQCLLDIVDDkIDIYLTVPQKVDLSQAL 982
Cdd:PRK05729 745 LPLLL----KGADAEDRARLEA-NEAYIKRLARL-ESLEI----LADDEEAPEGAASAVVGG-AELFLPLEGLIDVEAEL 813
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 983 QKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESV------KLLN-EEKINQLIATIASLE 1034
Cdd:PRK05729 814 ARLEKELAKLEKEIERVEKKLSNEGFvAKAPEEVvekereKLAEyEEKLAKLKERLARLK 873
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
16-1043 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 928.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 16 KKSLESPMPQSYCPKDVESDWDNLWCSCGFFSpnferAKTLSQEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRM 95
Cdd:PLN02381 89 KKRLSSQMAKQYSPSAVEKSWYAWWEKSGYFG-----ADAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRM 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 96 CDKEVLWIPGTDHAGIATQTVVERILLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEY 175
Cdd:PLN02381 164 SGYNALWVPGVDHAGIATQVVVEKKLMRERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQ 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 176 MSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQKPTRLRIPGYDKTVEVGILWYFSYPLQQkgqqys 255
Cdd:PLN02381 244 RSKAVTEAFVRLYKEGLIYRDIRLVNWDCTLRTAISDVEVDYIDIKERTLLKVPGYDKPVEFGVLTSFAYPLEG------ 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 256 whfepenlsKIPKITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPFlPERKIRIITD-EYVDPEFGTGCVKITPA 334
Cdd:PLN02381 318 ---------GLGEIVVATTRIETMLGDTAIAIHPDDERYKHLHGKFAVHPF-NGRKLPIICDaILVDPNFGTGAVKITPA 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 335 HDKNDFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCAS-FSGIHRFSCRELCEKELSRLNLLVDKTPNtkSMQLP 413
Cdd:PLN02381 388 HDPNDFEVGKRHN-----------LEFINIFTDDGKINSNGGSeFAGMPRFAAREAVIEALQKKGLYRGAKNN--EMRLG 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 414 ICSRSDDIVELIMIPQWWMNCKPFAEMACQAV---RNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAYRVCM 490
Cdd:PLN02381 455 LCSRTNDVVEPMIKPQWFVNCSSMAKQALDAAidgENKKLEFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYVTL 534
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 491 ENiNAEKK---PQDIWVAADSEEEAIKEVINKFQLKlgEFTVERDTDVLDTWFSSGLIPFSSLGWPyklnprTGKDDLST 567
Cdd:PLN02381 535 ED-DQLKElgsYNDHWVVARNESDALLEASQKFPGK--KFELSQDPDVLDTWFSSGLFPLSVLGWP------DDTDDLKA 605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 568 FFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEGISLEDLNSKVKKG 647
Cdd:PLN02381 606 FYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRKVYLHPMIRDAHGRKMSKSLGNVIDPLEVINGISLEGLHKRLEEG 685
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 648 NLPTSEIKRSIESNSKDFPTGIPECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGnieklKVYSE 727
Cdd:PLN02381 686 NLDPKELVVAKEGQKKDFPNGIAECGTDALRFALVSYTAQSDKINLDILRVVGYRQWCNKLWNAVRFAMS-----KLGDD 760
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 728 STKFQALSlnniLENYYSYLMWedffIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNNS 807
Cdd:PLN02381 761 YTPPATLS----VETMPFSCKW----ILSVLNKAISKTVSSLDAYEFSDAASTVYSWWQYQFCDVFIEAIKPYFAGDNPE 832
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 808 -KSAFVAAQ-VLCTCIDFGLRLLHPMIPFVTEELYQRLYQlVSSPERFLSISIAKFPTTLKhSQLNYKKDLEYKIMMRIV 885
Cdd:PLN02381 833 fASERAAAQdTLWICLDTGLRLLHPFMPFVTEELWQRLPQ-PKDHTRKDSIMISEYPSAVE-AWTNEKVEYEMDLVLSTV 910
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 886 SQIRSLTSIMeIPNKEKLSITVYIIYKGQD-CDTIQlletVAESFITKLANIgSTVTVInpdIKKVNELKSQCLLDIVDD 964
Cdd:PLN02381 911 KCLRSLRAEV-LEKQKNERLPAFALCRNQEiAAIIK----SHQLEILTLANL-SSLKVL---LSENDAPPAGCAFENVNE 981
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 965 KIDIYLTVPQKVDLSQALQKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESVKllnEEKINQLIATIASLEIAKENVESL 1043
Cdd:PLN02381 982 NLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQEKLEKKMNASGYkEKVPANIQ---EEDARKLTKLLQELEFFEKESKRL 1058
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
23-1024 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 865.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 23 MPQSYCPKDVESDWDNLWCSCGFFSPNFERAKtlsqeEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLW 102
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPDGNSNK-----PPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLW 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 103 IPGTDHAGIATQTVVERILLKsENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQ 182
Cdd:TIGR00422 76 LPGTDHAGIATQVKVEKKLGA-EGKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 183 AFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQkptrlripgydktvevGILWYFSYPLqqkgqqyswhfepEN 262
Cdd:TIGR00422 155 AFVRLYEKGLIYRGEYLVNWDPKLNTAISDIEVEYKEVK----------------GKLYYIRYPL-------------AN 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 263 LSKiPKITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPFLPeRKIRIITDEYVDPEFGTGCVKITPAHDKNDFDV 342
Cdd:TIGR00422 206 GSK-DYLVVATTRPETMFGDTAVAVHPEDERYKHLIGKKVILPLTG-RKIPIIADEYVDMEFGTGAVKVTPAHDFNDYEW 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 343 ATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDKTPNTksMQLPICSRSDDIV 422
Cdd:TIGR00422 284 GKRHN-----------LEFINILDEDGLLNENAGKYQGLTRFEARKKIVEDLKEEGLLVKIEPHT--HNVGTCWRSGTVV 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 423 ELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAYrvcmeninAEKKPQDI 502
Cdd:TIGR00422 351 EPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWLRNIKDWCISRQLIWGHRIPVW--------YCKECGEV 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 503 WVaADSEEEAIKEVinkfqlKLG-EFTVERDTDVLDTWFSSGLIPFSSLGWPYKlnprtgKDDLSTFFPTTLLETGSDIL 581
Cdd:TIGR00422 423 YV-AKEEPLPDDKT------NTGpSVELEQDTDVLDTWFSSSLWPFSTLGWPDE------TKDLKKFYPTDLLVTGYDII 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 582 FFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesn 661
Cdd:TIGR00422 490 FFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDVIE---------------------------- 541
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 662 skdfptgipECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKFQALSlnnile 741
Cdd:TIGR00422 542 ---------KYGADALRFTLASLVTPGDDINFDWKRVESARNFLNKLWNASRFVLMNLSDDLELSGGEEKLSLA------ 606
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 742 nyysylmweDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKElNNSKSAFVAAQVLCTCI 821
Cdd:TIGR00422 607 ---------DRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFCDWYIELVKYRLYN-GNEAEKKAARDTLYYVL 676
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 822 DFGLRLLHPMIPFVTEELYQRLyqlvssPERFLSISIAKFPTTLKhSQLNYKKDLEYKIMMRIVSQIRSLTSIMEIPNKE 901
Cdd:TIGR00422 677 DKALRLLHPFMPFITEEIWQHF------KEGADSIMLQSYPVVDA-EFVDEEAEKAFELLKEIIVSIRNLKAESNIPPNA 749
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 902 KLsiTVYIIYKgqDCDTIQLLETvAESFITKLANIGSTVTVINPDikkvnelKSQCLLDIVDDKIDIYLTVPQKVDLSQA 981
Cdd:TIGR00422 750 PL--KVLLIYT--EAETAERLKL-NAVDIKGAINFSEVEVVIEKP-------EVTEAVVELVPGFEIIIPVKGLINKAKE 817
|
970 980 990 1000
....*....|....*....|....*....|....*....|....
gi 209876528 982 LQKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESVKLLNEEKIN 1024
Cdd:TIGR00422 818 LARLQKQLDKEKKEVIRIEGKLENEGFvKKAPKEVIEKEKEKLE 861
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
23-1034 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 729.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 23 MPQSYCPKDVESDWDNLWCSCGFFSPNferaKTLSQEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLW 102
Cdd:PRK14900 15 LAKGYEHREVEARWYPFWQERGYFHGD----EHDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLW 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 103 IPGTDHAGIATQTVVERILLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQ 182
Cdd:PRK14900 91 LPGTDHAGIATQMIVEKELKKTEKKSRHDLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAVRE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 183 AFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEVIEVQKptrlripgydktvevGILWYFSYPLQQKGQQyswhfepen 262
Cdd:PRK14900 171 VFVRLHEEGLIYREKKLINWCPDCRTALSDLEVEHEEAHQ---------------GELWSFAYPLADGSGE--------- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 263 lskipkITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPFLpERKIRIITD-EYVDPEFGTGCVKITPAHDKNDFD 341
Cdd:PRK14900 227 ------IVVATTRPETMLGDTAVAVHPLDPRYMALHGKKVRHPIT-GRTFPIVADaILVDPKFGTGAVKVTPAHDFNDFE 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 342 VATRYnnkykddpsmeQLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLvdktPNTKSMQLPI--CSRSD 419
Cdd:PRK14900 300 VGKRH-----------GLEMITVIGPDGRMTAEAGPLAGLDRFEARKEVKRLLAEQGLD----RGAKPHVLPLgrCQRSA 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 420 DIVELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAyrvcmeninaekkp 499
Cdd:PRK14900 365 TILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEQWTNTYMAWMRNIHDWCISRQLWWGHQIPA-------------- 430
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 500 qdiWVAADSEEEAIKEVINKFQlKLGEFTVERDTDVLDTWFSSGLIPFSSLGWPYKlnprtgKDDLSTFFPTTLLETGSD 579
Cdd:PRK14900 431 ---WYCPDGHVTVARETPEACS-TCGKAELRQDEDVLDTWFSSGLWPFSTMGWPEQ------TDTLRTFYPTSVMETGHD 500
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 580 ILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEViegisledlnskvkkgnlptseikrsie 659
Cdd:PRK14900 501 IIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSKTKGNVIDPLVI---------------------------- 552
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 660 snskdfptgIPECGADALRYGLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKFQALSLnni 739
Cdd:PRK14900 553 ---------TEQYGADALRFTLAALTAQGRDIKLAKERIEGYRAFANKLWNASRFALMNLSGYQERGEDPARLARTP--- 620
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 740 lenyysylmwEDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNNSKSAFVAAqVLCT 819
Cdd:PRK14900 621 ----------ADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEALASEDPEARRSVQA-VLVH 689
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 820 CIDFGLRLLHPMIPFVTEELYQRLYQLVSSPERFLSISIAKFPttlKHSQLNYKKDLEYKIMMRIVSQIRSLTSIMEIPN 899
Cdd:PRK14900 690 CLQTSYRLLHPFMPFITEELWHVLRAQVGASAWADSVLAAEYP---RKGEADEAAEAAFRPVLGIIDAVRNIRGEMGIPW 766
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 900 KEKLSITVYIIYKGQDCDTIQLLETVAESFITKLANI-GSTVTVINPDIKKVNELKSqclldiVDDKIDIYLTVPQKVDL 978
Cdd:PRK14900 767 KVKLGAQAPVEIAVADPALRDLLQAGELARVHRVAGVeGSRLVVAAATAPAPQSAVG------VGPGFEVRVPLAGVIDL 840
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*..
gi 209876528 979 SQALQKIDKQLAVNKKSLESYEIKKKSPAY-DKVPESVKLLNEEKINQLIATIASLE 1034
Cdd:PRK14900 841 AAETARVDKEIGKVDQDLAVLERKLQNPSFvQNAPPAVVEKDRARAEELREKRGKLE 897
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
38-1015 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 686.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 38 NLWCSCGFFSPNFERAKtlsqeEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVV 117
Cdd:PLN02943 71 NWWESQGYFKPNFDRGG-----DPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDHAGIATQLVV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 118 ERiLLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGT 197
Cdd:PLN02943 146 EK-MLASEGIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVRLHEKGLIYQGS 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 198 RLVSWCSYLRTALSDIEVEVIEvqkptrlripgydktvEVGILWYFSYPLQQKGQQYswhfepenlskipkITVATTRLE 277
Cdd:PLN02943 225 YMVNWSPNLQTAVSDLEVEYSE----------------EPGTLYYIKYRVAGGSEDF--------------LTIATTRPE 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 278 TMLGDVAVAVHPNDERYKDLVGNICLHPFLPERKIRIITDEYVDPEFGTGCVKITPAHDKNDFDVATRYNnkykddpsme 357
Cdd:PLN02943 275 TLFGDVAIAVNPEDDRYSKYIGKMAIVPMTYGRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKLG---------- 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 358 qLEFISIFTLDGKMSNNcasfSGIHRFSCRELCEKELSRLNLLVDKTPNTksMQLPICSRSDDIVELIMIPQWWMNCKPF 437
Cdd:PLN02943 345 -LPILNVMNKDGTLNEV----AGLYWFEAREKLWSDLEETGLAVKKEPHT--LRVPRSQRGGEVIEPLVSKQWFVTMEPL 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 438 AEMACQAVRNKELVIEPKFHEQTWFHWLENIQDWCISRQLWWGHRIPAYRVcmeninAEKKPQDIWVAADSEEEAIKevi 517
Cdd:PLN02943 418 AEKALKAVENGELTIIPERFEKIYNHWLSNIKDWCISRQLWWGHRIPVWYI------VGKDCEEDYIVARSAEEALE--- 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 518 nKFQLKLGE-FTVERDTDVLDTWFSSGLIPFSSLGWPyklnpRTGKDDLSTFFPTTLLETGSDILFFWVARMVMLSYACT 596
Cdd:PLN02943 489 -KAREKYGKdVEIYQDPDVLDTWFSSALWPFSTLGWP-----DVSAEDFKKFYPTTVLETGHDILFFWVARMVMMGIEFT 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 597 GKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesnskdfptgipECGADA 676
Cdd:PLN02943 563 GTVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIK-------------------------------------EFGTDA 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 677 LRYgLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKFQALSLNNilENYYSYLMWEDFFIIH 756
Cdd:PLN02943 606 LRF-TLALGTAGQDLNLSTERLTSNKAFTNKLWNAGKFVLQNLPSQSDTSAWEHILACKFDK--EESLLSLPLPECWVVS 682
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 757 RLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVT 836
Cdd:PLN02943 683 KLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASKTRLYHSGDNSALSRAQAVLLYVFENILKLLHPFMPFVT 762
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 837 EELYQRLyqlvssPERFLSISIAKFPTTLKHSQLNYKKDLE-YKIMMRIVSQIRSLTSIMeiPNKEklsITVYIIykgQD 915
Cdd:PLN02943 763 EELWQAL------PYRKEALIVSPWPQTSLPKDLKSIKRFEnLQSLTRAIRNARAEYSVE--PAKR---ISASIV---AS 828
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 916 CDTIQLLETVAE--SFITKLanigstvtvinpDIKKVNELKS------QCLLDIVDDKIDIYLTVPQKVDLSQALQKIDK 987
Cdd:PLN02943 829 AEVIEYISKEKEvlALLSRL------------DLQNVHFTDSppgdanQSVHLVASEGLEAYLPLADMVDISAEVERLSK 896
|
970 980
....*....|....*....|....*....
gi 209876528 988 QLAVNKKSLESYEIKKKSPAY-DKVPESV 1015
Cdd:PLN02943 897 RLSKMQTEYDALAARLSSPKFvEKAPEDV 925
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
35-694 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 597.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 35 DWDNLWCSCGFFSPNFERAKTlsqEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQ 114
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRKG---KPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 115 TVVERILLKSENKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIY 194
Cdd:pfam00133 78 QVVEKKLGIKEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 195 RGTRLVSWCSYLRTALSDIEVEVIEVQKPtrlripgydktvevgiLWYFSYPLQQKgqqyswhfepenlsKIPKITVATT 274
Cdd:pfam00133 158 RGKKLVNWSPALNTALSNLEVEYKDVKGP----------------SIHVAFPLADD--------------EGASLVIWTT 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 275 RLETMLGDVAVAVHPN-------------------------------DERYKDLVGNICLHPFLPeRKIRIITDEYVDPE 323
Cdd:pfam00133 208 TPWTLPGNTAVAVNPEfdyvitgegyilaeallkslykkgtdkkileDFRGKELEGKEAIHPFVN-REIPIITDDYVDME 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 324 FGTGCVKITPAHDKNDFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDK 403
Cdd:pfam00133 287 FGTGAVHIAPAHGENDYEVGQRHN-----------LEVINPVDDDGTFTEEAPDFQGVYRFDARKKIVELLTEKGLLLKI 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 404 TPNTksMQLPICSRSDDIVELIMIPQWWMNCKPFAEMACQAVRNKELViePKFHEQTWFHWLENIQDWCISRQLWWGHRI 483
Cdd:pfam00133 356 EPFT--HSYPFCWRSGTPIIPRATPQWFVRMDELADQALEAVEKVQFV--PKSGEKRYFNWLANIQDWCISRQRWWGHPI 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 484 PAYRVCMENINAEKKPQDIWVAADSEEEAI-----KEVINKFQLKLGEFtvERDTDVLDTWFSSGLIPFSSLGWPYKLNP 558
Cdd:pfam00133 432 PAWVSKDTEEVVCRGELFELVAGRFEEEGSikwlhREAKDKLGYGKGTL--EQDEDVLDTWFSSGSWPFSTLGWPFVNTE 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 559 rtgkdDLSTFFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisle 638
Cdd:pfam00133 510 -----EFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGSVPFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVID----- 579
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 209876528 639 dlnskvkkgnlptseikrsiesnskdfptgipECGADALRYgLLAYTKQGRNINLD 694
Cdd:pfam00133 580 --------------------------------KYGADALRL-WLANSDYGRDINLS 602
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
60-693 |
1.31e-169 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 502.16 E-value: 1.31e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 60 EKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERILLKsENKSRHDYGRDEFLT 139
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGI-EGKTRHDLGREEFLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 140 RVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCsylrtalsdievevie 219
Cdd:cd00817 80 KCWEWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWC---------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 220 vqkptrlripgydktvevgilwyfsyplqqkgqqyswhfepenlskipkitvatTRLETmlgdvAVAvhpnderykdlvg 299
Cdd:cd00817 144 ------------------------------------------------------PKLRT-----AIS------------- 151
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 300 niclhpflperkiriitdeyvdpefgtgcvkitpahdkndfdvatrynnkykddpsmeqlefisiftldgkmsnncasfs 379
Cdd:cd00817 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 380 gihrfscrelcekelsrlnllvdktpntksmQLPICSRSDDIVELIMIPQWWMNCKPFAEMACQAVRNKELVIEPKFHEQ 459
Cdd:cd00817 152 -------------------------------DIEVCSRSGDVIEPLLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEK 200
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 460 TWFHWLENIQDWCISRQLWWGHRIPAYRVcmENINAekkpqdiWVAADSEEEAIKEVINKFQLKLGEFTVERDTDVLDTW 539
Cdd:cd00817 201 RYENWLENIRDWCISRQLWWGHRIPAWYC--KDGGH-------WVVAREEDEAIDKAAPEACVPCGGEELKQDEDVLDTW 271
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 540 FSSGLIPFSSLGWPyklnprTGKDDLSTFFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMS 619
Cdd:cd00817 272 FSSSLWPFSTLGWP------EETKDLKKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGKLPFKEVYLHGLVRDEDGRKMS 345
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 209876528 620 KSLGNVIDPLEVIEGIsledlnskvkkgnlptseikrsiesnskdfptgipecGADALRYGLLAYTKQGRNINL 693
Cdd:cd00817 346 KSLGNVIDPLDVIDGY-------------------------------------GADALRFTLASAATQGRDINL 382
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
20-953 |
1.91e-133 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 422.68 E-value: 1.91e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 20 ESPMPQSYCPKDVESDWDNLWCSCGFFSpnFERAKTlsqEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKE 99
Cdd:PRK13208 3 MPELPKKYDPEELEEKWQKIWEEEGTYK--FDPDER---KPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 100 VLWIPGTDHAGIATQTVVERILlkseNKSRHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYmSKA 179
Cdd:PRK13208 78 VFFPQGWDDNGLPTERKVEKYY----GIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISPE-YRR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 180 VSQ-AFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVEvievqkptrlripgyDKTVEvGILWYFSYPLQQKGqqyswhf 258
Cdd:PRK13208 153 ISQkSFLDLYKKGLIYRAEAPVLWCPRCETAIAQAEVE---------------YRERE-GKLNYIKFPVEDGE------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 259 epenlskipKITVATTRLETMLGDVAVAVHPNDERYKDLVGNICLHPfLPERKIRIITDEYVDPEFGTGCVKITPAHDKN 338
Cdd:PRK13208 210 ---------EIEIATTRPELLPACVAVVVHPDDERYKHLVGKTAIVP-LFGVEVPILADPLVDPDFGTGAVMICTFGDKT 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 339 DFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDKTPNTKSmqLPICSRS 418
Cdd:PRK13208 280 DVTWWRELN-----------LPTRIIIDEDGRMTEAAGKLAGLTIEEARKKIVEDLKSGGLLGKQEPIKHN--VKFCERC 346
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 419 DDIVELIMIPQWWMNCKPFAEMACQAVRnkELVIEPKFHEQTWFHWLENIQ-DWCISRQLWWGHRIPA-YRV-CMENINA 495
Cdd:PRK13208 347 DTPLEILVTRQWFIKVLDLKEELLERGK--EINWYPEHMRVRLENWIEGLNwDWCISRQRYFGTPIPVwYCKdCGHPILP 424
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 496 EKK--PQDIWVAA---DSEEeaikevinkfQLKLGEFTVErdTDVLDTWFSSGLIPFSSLGWPyklnprTGKDDLSTFFP 570
Cdd:PRK13208 425 DEEdlPVDPTKDEppgYKCP----------QCGSPGFEGE--TDVMDTWATSSITPLIVTGWE------RDEDLFEKVFP 486
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 571 TTLLETGSDILFFW----VARmvmlSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEgisledlnskvkk 646
Cdd:PRK13208 487 MDLRPQGHDIIRTWlfytILR----AYLLTGKLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEELLE------------- 549
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 647 gnlptseikrsiesnskdfptgipECGADALRYgLLAYTKQGRNINLDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYS 726
Cdd:PRK13208 550 ------------------------KYGADAVRY-WAASARLGSDTPFDEKQVKIGRRLLTKLWNASRFVLHFSADPEPDK 604
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 727 EStkfqalSLNNIlenyysylmweDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNN 806
Cdd:PRK13208 605 AE------VLEPL-----------DRWILAKLAKVVEKATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRAYGEDE 667
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 807 SKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRLYQlvssperfLSISIAKFPTTLKhsQLNYKKDLEY-KIMMRIV 885
Cdd:PRK13208 668 EEEQKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWLYG--------GSVHRASWPEPDE--ELIDEEDEELgELAKEIL 737
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 209876528 886 SQIRSLTSIMEIPNKEKL-SITVYIIykgqdcDTIQLLETVAESfITKLANIGSTVTVINPDIKKVNEL 953
Cdd:PRK13208 738 SAVRKYKSEAGLSLNAPLkKVEVYGP------ADLELLEAAEED-LKAAGNIEELELVEGDPELEVEII 799
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
68-932 |
5.03e-76 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 269.64 E-value: 5.03e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 68 PPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTD-HaG--IATQtvVERiLLKSENKSRHDYGRDEF------- 137
Cdd:COG0060 54 PPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGWDcH-GlpIELK--VEK-ELGIKKKDIEKVGIAEFrekcrey 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 138 -LTRVWDWKKkyganictQLRRLGCSFDWTREMFTMD-EYMSKAVsQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEV 215
Cdd:COG0060 130 aLKYVDEQRE--------DFKRLGVWGDWDNPYLTMDpEYEESIW-WALKKLYEKGLLYKGLKPVPWCPRCGTALAEAEV 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 216 EVIEVQkptrlripgyDKTVEVGilwyfsYPLqqKGQQYSWHFEPENLskipkitVA-TTRLETMLGDVAVAVHP----- 289
Cdd:COG0060 201 EYKDVT----------SPSIYVK------FPV--KDEKALLLLEDAYL-------VIwTTTPWTLPANLAVAVHPdidyv 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 290 -----NDERY---------------------------KDLVGNICLHPFL----PERKIRIITDEYVDPEFGTGCVKITP 333
Cdd:COG0060 256 lvevtGGERLilaealveavlkelgiedyevlatfkgAELEGLRYEHPFYyvvgYDRAHPVILGDYVTTEDGTGIVHTAP 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 334 AHDKNDFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFSC-RELCEKeLSRLNLLVDKTPNTKSMql 412
Cdd:COG0060 336 GHGEDDFEVGKKYG-----------LPVLNPVDDDGRFTEEAPLFAGLFVKDAnPAIIED-LKERGALLAREKITHSY-- 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 413 PICSRSDDivELIM--IPQWwmnckpFAEMacQAVRNKEL-VIE-----PKfHEQTWFH-WLENIQDWCISRQLWWGHRI 483
Cdd:COG0060 402 PHCWRCKT--PLIYraTPQW------FISM--DKLRDRALeAIEkvnwiPE-WGEGRFGnMLENRPDWCISRQRYWGVPI 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 484 PAYR-----------VCMENINA--EKKPQDIWVAADSEEEAIKEVINKFQLKlGEFtvERDTDVLDTWFSSGLIPFSSL 550
Cdd:COG0060 471 PIWVcedcgelhrteEVIGSVAEllEEEGADAWFELDLHRPFLDETLKCPKCG-GTM--RRVPDVLDVWFDSGSMHFAVL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 551 gwpyklnprTGKDDLStfFPTTL-LEtGSD---------ILffwvarmvmLSYACTGKLPFKTVYLHAMVRDAQGRKMSK 620
Cdd:COG0060 548 ---------ENREELH--FPADFyLE-GSDqtrgwfyssLL---------TSTALFGRAPYKNVLTHGFVLDEDGRKMSK 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 621 SLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesnsKDfptgipecGADALRYgLLAYTKQGRNINLD---IKR 697
Cdd:COG0060 607 SLGNVVDPQEVID-----------------------------KY--------GADILRL-WVASSDYWGDLRFSdeiLKE 648
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 698 VV-AYRhfcnKLWNACKFAFGNIEKlkvYSESTkfQALSLNNILEnyysylmwEDFFIIHRLNECITKVSASFKEYLFAE 776
Cdd:COG0060 649 VRdVYR----RLRNTYRFLLANLDD---FDPAE--DAVPYEDLPE--------LDRWILSRLNELIKEVTEAYDNYDFHR 711
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 777 VVAATYNFWLYELCDIYLELTKLRF-KELNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRLyqlvsSPERFLS 855
Cdd:COG0060 712 AYRALHNFCVEDLSNWYLDISKDRLyTEAADSLDRRAAQTTLYEVLETLVRLLAPILPFTAEEIWQNL-----PGEAEES 786
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 856 ISIAKFPTTLKhSQLNykKDLEYKimMRIVSQIRSL-TSIMEIPNKEKL-------SITVYIiykgqDCDTIQLLETV-- 925
Cdd:COG0060 787 VHLADWPEVDE-ELID--EELEAK--WDLVREVRSAvLKALEAARKEKLirqpleaAVVLYA-----DEELAAALESLgd 856
|
....*....
gi 209876528 926 --AESFITK 932
Cdd:COG0060 857 llAEELNVS 865
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
693-843 |
4.41e-48 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 167.35 E-value: 4.41e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 693 LDIKRVVAYRHFCNKLWNACKFAFGNIEKLKVYSESTKfqALSLnnilenyysylmwEDFFIIHRLNECITKVSASFKEY 772
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDEPEEDPE--SLSL-------------ADRWILSRLNKTVEEVTEALENY 65
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 209876528 773 LFAEVVAATYNFWLYELCDIYLELTKLRFKElNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRL 843
Cdd:cd07962 66 RFSEAATALYEFFWNDFCDWYLELVKPRLYG-EDEEEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
50-865 |
1.02e-47 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 184.97 E-value: 1.02e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 50 FERAKTLSQEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIAtqtvVERILLKS-ENKS 128
Cdd:PLN02843 22 YKRVSDRNNGESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLP----IELKVLQSlDQEA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 129 RHDYGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRT 208
Cdd:PLN02843 98 RKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKPVHWSPSSRT 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 209 ALSDIEVEVIEVQKPTRLripgydktvevgilwYFSYPLQQKGQQyswhFEPENLSKIPKITVA--TTRLETMLGDVAVA 286
Cdd:PLN02843 178 ALAEAELEYPEGHVSKSI---------------YVAFPVVSPSET----SPEELEEFLPGLSLAiwTTTPWTMPANAAVA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 287 VHP-------------NDERYK-----------------------------------------------DLVGNICLHPF 306
Cdd:PLN02843 239 VNDklqysvvevqsfsEDESTSggnkkkrpgnvlkeqqklflivatdlvpaleakwgvklvvlktfpgsDLEGCRYIHPL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 307 LPERKIRIITDEYVDPEFGTGCVKITPAHDKNDFDVATRYNnkykddpsmeqLEFISIFTLDGKMSNNCASFSGIHRFS- 385
Cdd:PLN02843 319 YNRESPVVIGGDYITTESGTGLVHTAPGHGQEDYITGLKYG-----------LPLLSPVDDAGKFTEEAGQFSGLSVLGe 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 386 -CRELCEKELSRLNLLVD-----KTP---NTKSmqlPICSRSDDivelimipQWWMNCKPFAEMACQAVRNKELViePKF 456
Cdd:PLN02843 388 gNAAVVEALDEAGSLLMEeayghKYPydwRTKK---PTIFRATE--------QWFASVEGFRQAALDAIDKVKWI--PAQ 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 457 HEQTWFHWLENIQDWCISRQLWWGHRIPAY------RVCM--ENIN-----AEKKPQDIWVAADSEE---EAIKEVINKF 520
Cdd:PLN02843 455 GENRIRAMVSGRSDWCISRQRTWGVPIPVFyhvetkEPLMneETIAhvksiVAQKGSDAWWYMDVEDllpEKYRDKASDY 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 521 qlklgeftvERDTDVLDTWFSSGlipfSSlgWPYKLNPRTGkddLStfFPTTLLETGSDILFFWVARMVMLSYACTGKLP 600
Cdd:PLN02843 535 ---------EKGTDTMDVWFDSG----SS--WAGVLGSREG---LS--YPADLYLEGSDQHRGWFQSSLLTSVATKGKAP 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 601 FKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIEGisledlnskvkkGNlptseikrsiesNSKDFPTgipeCGADALRYG 680
Cdd:PLN02843 595 YKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIEG------------GK------------NQKQEPA----YGADVLRLW 646
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 681 LLA--YTKQ---GRNInldIKRVV-AYRhfcnKLWNACKFAFGNIEKLKVySESTKFQALSlnnILENYysylmwedffI 754
Cdd:PLN02843 647 VASvdYTGDvliGPQI---LKQMSdIYR----KLRGTLRYLLGNLHDWKP-DNAVPYEDLP---SIDKY----------A 705
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 755 IHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKLRFKELNNSKSAFVAAQ-VLCTCIDFGLRLLHPMIP 833
Cdd:PLN02843 706 LFQLENVVNEIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLYVGGTTSFTRRSCQtVLAAHLLSLLRAIAPILP 785
|
890 900 910
....*....|....*....|....*....|...
gi 209876528 834 FVTEELYQRL-YQLVSSPERFlsISIAKFPTTL 865
Cdd:PLN02843 786 HLAEDAWQNLpFQEDGSAAES--VFEAGWPTPN 816
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
50-851 |
1.15e-37 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 153.58 E-value: 1.15e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 50 FERAKTLSQEEK-FVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERillksENK- 127
Cdd:PTZ00427 91 FNTSNKLAKNKKaYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLPIEYEIEK-----ENNi 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 128 -SRHD---YGRDEFLTRVWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWC 203
Cdd:PTZ00427 166 nKKEDilkMGIDVYNEKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNNYVYKSFKVMPYS 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 204 SYLRTALSDIEVEVIEVQKPtrlripgyDKTVEVGILWYFSYP-----------LQQKGQQYS----------------- 255
Cdd:PTZ00427 246 CKCNTPISNFELNLNYKDTP--------DPSIIISFVLCSDFPkveeecnieedKQLLGEKYSvlynnkrensnngnnns 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 256 -------------------WHFePENLS----------KIPKI------TVATTRLETMLGDVAVAV------------H 288
Cdd:PTZ00427 318 tnnvcyaqhseilawtttpWTL-PSNLAlcvnehftylRIHHVksnrvvIVGECRLEWIMKELKWNVedlkivnrfkgkE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 289 PNDERYKDLVGNICLHPFLPERKIRIITDEYVDPEFGTGCVKITPAHDKNDFDVATRYNnkyKDDPsmEQLEFISIFTLD 368
Cdd:PTZ00427 397 LKGLRYKPLFTNFYEKYNFKERAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNG---VIDP--EKNIFIDPLDAN 471
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 369 GKMSNNCASFSGIHRFSCRELCEKELSRLNLLVDKtpNTKSMQLPICSRSDDIVELIMIPQWWMNCkpfAEMACQAVRNK 448
Cdd:PTZ00427 472 GYFTNEVEEVQNLYIKEADNVIKKKLKNENRLLSN--NTIVHSYPFCWRSDTPLIYRAIPAWFIRV---SNSTNELVKNN 546
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 449 EL-------VIEPKFHeqtwfHWLENIQDWCISRQLWWGHRIPAYR-------VCMENINAEKKPQDIWVAADSEEEAIK 514
Cdd:PTZ00427 547 ETtywipahIKEKKFH-----NWIKDAKDWCISRNRYWGTPIPIWAdekmetvICVESIKHLEELSGVKNINDLHRHFID 621
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 515 EVINKFQLKLGEFTVERDTDVLDTWFSSGLIPFSSLGWPYKlnprTGKDDLSTFFPTTLLETGSDILFFWVARMVMLSYA 594
Cdd:PTZ00427 622 HIEIKNPKGKTYPKLKRIPEVFDCWFESGSMPYAKVHYPFS----TEKEDFHKIFPADFIAEGLDQTRGWFYTLLVISTL 697
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 595 CTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVI-----EGISLEDLNS-KVKKGNLPTSEikRSIESNSKDFptg 668
Cdd:PTZ00427 698 LFDKAPFKNLICNGLVLASDGKKMSKRLKNYPDPLYILdkygaDSLRLYLINSvAVRAENLKFQE--KGVNEVVKSF--- 772
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 669 ipecgadalrygLLAYTKQGRNINLDIKRVvayrhfcnKLWNACKFAFGNIeklKVYSEStkfqalslnNILenyysylm 748
Cdd:PTZ00427 773 ------------ILPFYHSFRFFSQEVTRY--------ECLNKKQFLFNTD---YIYKND---------NIM-------- 812
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 749 weDFFIIHRLNECITKVSASFKEYLFAEVVAATYNFwLYELCDIYLELTKLRFKELNNSKSAFVAAQVLCTCIDFGLRLL 828
Cdd:PTZ00427 813 --DQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQF-IENLTNWYIRLNRDRMRGSLGEENCLQSLCTTYRTLHLFTVLM 889
|
890 900
....*....|....*....|...
gi 209876528 829 HPMIPFVTEELYQRLYQLVSSPE 851
Cdd:PTZ00427 890 APFTPFITEYIYQQLRRVKSTNE 912
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
428-633 |
2.91e-36 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 139.86 E-value: 2.91e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 428 PQWWMNCKPFAEMACQAVRNKELVIEpkfHEQTWFH-WLENIQDWCISRQLWWGHRIPayrvcmeninaekkpqdiwvaa 506
Cdd:cd00668 140 EQWFFDMPKFKEKLLKALRRGKIVPE---HVKNRMEaWLESLLDWAISRQRYWGTPLP---------------------- 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 507 dseeeaikevinkfqlklgeftverdTDVLDTWFSSGLIPFSSLGWPYklnprtGKDDLSTFFPTTLLETGSDILFFWVA 586
Cdd:cd00668 195 --------------------------EDVFDVWFDSGIGPLGSLGYPE------EKEWFKDSYPADWHLIGKDILRGWAN 242
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 209876528 587 RMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGNVIDPLEVIE 633
Cdd:cd00668 243 FWITMLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVVE 289
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
61-200 |
3.39e-36 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 139.48 E-value: 3.39e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 61 KFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERILLKsENKSRHdygRDEFLTR 140
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKGGR-KKKTIW---IEEFRED 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 141 VWDWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLV 200
Cdd:cd00668 77 PKEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGTHPV 136
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
68-907 |
8.85e-34 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 141.02 E-value: 8.85e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 68 PPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERillKSENKSRHD---YGRDEF------- 137
Cdd:PLN02882 46 PPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGWDCHGLPVEYEIDK---KLGIKRRDDvlkMGIDKYneecrsi 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 138 LTR-VWDWKKKyganictqLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEV- 215
Cdd:PLN02882 123 VTRySKEWEKT--------VTRTGRWIDFENDYKTMDPKFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTPLSNFEAg 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 216 -EVIEVQKPTrlripgydktVEVgilwyfSYPL---QQKGQQYSWHFEPENL-SKI-----PKIT--------------V 271
Cdd:PLN02882 195 lNYKDVSDPA----------VMV------SFPIvgdPDNASFVAWTTTPWTLpSNLalcvnPNFTyvkvrnkytgkvyiV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 272 ATTRLETMLGDVAVAVHPN-----DERY--------KDLVGN--ICLHPF---LPERKIRIITDEYVDPEFGTGCVKITP 333
Cdd:PLN02882 259 AESRLSALPTAKPKSKKGSkpenaAEGYevlakvpgSSLVGKkyEPLFDYfseFSDTAFRVVADDYVTDDSGTGVVHCAP 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 334 AHDKNDFDVATRYNNKYKDDpsmeqlEFISIFTLDGKMSNNCASFSGIH-RFSCRELCE--KELSRLnllVDKTPNTKSM 410
Cdd:PLN02882 339 AFGEDDYRVCLANGIIEKGG------NLPVPVDDDGCFTEKVTDFSGRYvKDADKDIIAaiKAKGRL---VKSGSITHSY 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 411 qlPICSRSDdiVELI--MIPQWWMNCKPFAEMACQavRNKELVIEPKFHEQTWFH-WLENIQDWCISRQLWWGHRIPayr 487
Cdd:PLN02882 410 --PFCWRSD--TPLIyrAVPSWFVKVEEIKDRLLE--NNKQTYWVPDYVKEKRFHnWLENARDWAVSRSRFWGTPLP--- 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 488 vcmeninaekkpqdIWVAADSEEEAIKEVINKFQLKLG----------------------EFTV-ERDTDVLDTWFSSGL 544
Cdd:PLN02882 481 --------------IWISDDGEEVVVIGSIAELEKLSGvkvtdlhrhfidhitipssrgpEFGVlRRVDDVFDCWFESGS 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 545 IPFSSLGWPYKlnprtGKDDLSTFFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLGN 624
Cdd:PLN02882 547 MPYAYIHYPFE-----NKELFEKNFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKN 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 625 VIDPLEVIEgisledlnskvkkgnlptseikrsiesnskdfptgipECGADALRYGL----------LAYTKQGrninld 694
Cdd:PLN02882 622 YPDPNEVID-------------------------------------KYGADALRLYLinspvvraepLRFKEEG------ 658
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 695 IKRVVAYRHFcnKLWNACKFAFGNIEKLKVYSeSTKFQALSLN------NILenyysylmweDFFIIHRLNECITKVSAS 768
Cdd:PLN02882 659 VFGVVKDVFL--PWYNAYRFLVQNAKRLEVEG-GAPFVPLDLAklqnsaNVL----------DRWINSATQSLVKFVREE 725
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 769 FKEYLFAEVVAATYNFwLYELCDIYLELTKLRFKELNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRLYQlvS 848
Cdd:PLN02882 726 MGAYRLYTVVPYLVKF-IDNLTNIYVRFNRKRLKGRTGEEDCRTALSTLYNVLLTSCKVMAPFTPFFTEVLYQNLRK--V 802
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 849 SPERFLSISIAKFPTTlKHSQLNYKKDLEYKIMMRIVSQIRSLTSIMEIPNKEKLS-ITV 907
Cdd:PLN02882 803 LPGSEESIHYCSFPQV-DEGELDERIEQSVSRMQTVIELARNIRERHNKPLKTPLKeMVV 861
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
751-907 |
7.26e-30 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 115.58 E-value: 7.26e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 751 DFFIIHRLNECITKVSASFKEYLFAEVVAATYNFWLYELCDIYLELTKlrfKELNNSKSAFVAAQVLCTCIDFGLRLLHP 830
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIK---DRLYGEEPDSRAQTTLYEVLETLLRLLAP 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 209876528 831 MIPFVTEELYQRlyqlvssperfLSISIAKFPTTLKHSQLNYKKDLEYkiMMRIVSQIRSLTSIMEIPNKEKLSITV 907
Cdd:pfam08264 78 FMPFITEELWQK-----------ESIHLAPWPEDAELEEAELEEAFEL--RQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
464-633 |
1.30e-28 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 118.10 E-value: 1.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 464 WLENIQDWCISRQLWWGHRIPayrvcmeninaekkpqdIWVAADSEEEaikevinkfqlklgefTVERDTDVLDTWFSSG 543
Cdd:cd00818 185 WLENRRDWCISRQRYWGTPIP-----------------VWYCEDCGEV----------------LVRRVPDVLDVWFDSG 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 544 LIPFSSLGWPYKlnprtgKDDLSTFFPTTLLETGSDILFFWVARMVMLSYACTGKLPFKTVYLHAMVRDAQGRKMSKSLG 623
Cdd:cd00818 232 SMPYAQLHYPFE------NEDFEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHGFVLDEDGRKMSKSLG 305
|
170
....*....|
gi 209876528 624 NVIDPLEVIE 633
Cdd:cd00818 306 NYVDPQEVVD 315
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
23-843 |
4.91e-22 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 102.44 E-value: 4.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 23 MPQSYCPKDVESDWDNLWCSCGFFspnfeRAKTLSQEEKF---VMaLPPPnvTGCLHIGHTLTSAIQDSLCRYHRMCDKE 99
Cdd:COG0495 1 MQERYNPKEIEKKWQKYWEENGTF-----KADEDSSKPKYyvlDM-FPYP--SGRLHMGHVRNYTIGDVVARYKRMQGYN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 100 VL----W----IPgTDHAGIATQTvverillksenksrHdygrdeflTRVWDWKkkygaNICT---QLRRLGCSFDWTRE 168
Cdd:COG0495 73 VLhpmgWdafgLP-AENAAIKNGV--------------H--------PAEWTYE-----NIANmrrQLKRLGLSYDWSRE 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 169 MFTMD-EY------MskavsqaFINLFNQGYIYRGTRLVSWCSYLRTALSDiEvEVIE----------VQKPTR---LRI 228
Cdd:COG0495 125 IATCDpEYykwtqwI-------FLQLYEKGLAYRKEAPVNWCPVDQTVLAN-E-QVIDgrcwrcgapvEKKELPqwfLKI 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 229 PGY------D-KTVEVgilWyfsyPLQQKGQQYSW---------HFEPENLSKipKITVATTRLETMLGD--VAVAV-HP 289
Cdd:COG0495 196 TDYadelldDlDKLDG---W----PEKVKTMQRNWigrsegaevDFPVEGSDE--KITVFTTRPDTLFGAtfMVLAPeHP 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 290 ----------NDE--RYKDLVGNI--------------------CLHPFLPErKIRI-ITDeYVDPEFGTGCVKITPAHD 336
Cdd:COG0495 267 lvkelatpeqNAAvaAFIEEAKKKseiertsetkektgvftglyAINPLTGE-KIPIwIAD-YVLMDYGTGAVMAVPAHD 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 337 KNDFDVATRYNNKYK------DDPSMEQLEfiSIFTLDGKMSNncasfSGihrfscrelcekelsrlnllvdktpntksm 410
Cdd:COG0495 345 QRDFEFAKKYGLPIKqviapeDGDDPDILE--EAYTGDGVLIN-----SG------------------------------ 387
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 411 qlpicsrsddivelimipqwwmnckPFAEMACQAVRNKelVIEpkfheqtwfhWLEN-------IQ----DWCISRQLWW 479
Cdd:COG0495 388 -------------------------EFDGLDSEEAKEA--IIE----------WLEEkglgkrkVNyrlrDWLISRQRYW 430
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 480 GHRIPAyrvcmenINAEKkpqDIWVAADSEEEAIK--EVINkFQLKLG-------EF----------TVERDTDVLDTWF 540
Cdd:COG0495 431 GEPIPI-------IHCED---CGVVPVPEDQLPVElpEDVD-FDPTGGsplarapEWvnvtcpkcggPARRETDTMDTFV 499
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 541 -SSglipfsslgWpYKL---NPR-----TGKDDLSTFFPTtlletgsD---------IL------FFWvarMVMlsYACt 596
Cdd:COG0495 500 dSS---------W-YYLrytDPHndeapFDPEAANYWLPV-------DqyiggiehaILhllyarFFT---KVL--RDL- 556
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 597 GKL----PFKTVYLHAMVRD--------AQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesnskd 664
Cdd:COG0495 557 GLVsfdePFKRLLTQGMVLEvgkdgvviGGIEKMSKSKGNVVDPDEIIE------------------------------- 605
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 665 fptgipECGADALR-YGL--------LAYTKQGrninldikrVV-AYRhFCNKLWNackFAFGNIEKLKVYSESTKFQAL 734
Cdd:COG0495 606 ------KYGADTLRlFEMfagpperdLEWSDSG---------VEgAYR-FLNRVWR---LVVDEAEALKLDVADLSEADK 666
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 735 SLNnilenyysylmwedfFIIHRLnecITKVSASFKEYLFAEVVAAtynfwLYELCDiylELTKLRFKELNNSKSAFVAA 814
Cdd:COG0495 667 ELR---------------RALHKT---IKKVTEDIERLRFNTAIAA-----LMELVN---ALYKAKDSGEADRAVLREAL 720
|
970 980
....*....|....*....|....*....
gi 209876528 815 QVLctcidfgLRLLHPMIPFVTEELYQRL 843
Cdd:COG0495 721 ETL-------VLLLAPFAPHIAEELWERL 742
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
75-909 |
3.52e-20 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 96.86 E-value: 3.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 75 LHIGHTLTSAIQDSLCRYHRMCDKEVLW-----IPGTDHAGIAtqtvvERILLKSEN-----KSRHDYGRDEF--LTRVW 142
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFpmafhVTGTPILGIA-----ERIARGDPEtielyKSLYGIPEEELekFKDPE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 143 DWKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTA------LSDIEVE 216
Cdd:PRK12300 76 YIVEYFSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPvgdhdlLDGEEPE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 217 VIEVqkptrlripgydktveVGILwyfsyplqqkgqqyswhFEPENLSKIPkitVATTRLETMLGDVAVAVHPN------ 290
Cdd:PRK12300 156 IVEY----------------TLIK-----------------FEESEDLILP---AATLRPETIFGVTNLWVNPDatyvka 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 291 ---DERY-------------------------KDLVGNICLHPfLPERKIRIITDEYVDPEFGTGCVKITPAHDKNDF-- 340
Cdd:PRK12300 200 evdGEKWivskeaaeklsfqdrdveiieeikgSELIGKKVKNP-VTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYva 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 341 -------------------------------DVATRYNNKYKDDPSMEQL-------EFISiftldGKMSNNCASFSGIH 382
Cdd:PRK12300 279 lrdlkknkelldviepiplievegygefpakEVVEKLGIKSQEDPELEEAtkevyraEFHK-----GVLKENTGEYAGKP 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 383 RFSCRELCEKELSRLNL------LvdktpntksMQLPICSRS-DDIVELIMIPQWWMNC--KPFAEMACQAVRNKELVie 453
Cdd:PRK12300 354 VREAREKITKDLIEKGIadimyeF---------SNRPVYCRCgTECVVKVVKDQWFIDYsdPEWKELAHKALDNMEII-- 422
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 454 PKFHEQTWFHWLENIQDWCISRQLWWGHRIP----------------------AYRVCMENINAEKKPQDIW-------- 503
Cdd:PRK12300 423 PEEYRKEFENTIDWLKDRACARRRGLGTRLPwdeewiieslsdstiymayytiAHKIREYGIKPEQLTPEFFdyvflgkg 502
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 504 -VAADSEEEAI-KEVINKFQlklGEFtverdtdvldtwfssglipfssLGWpYKLNPR-TGKDDLS---TFFpttlletg 577
Cdd:PRK12300 503 dPEEVSKKTGIpKEILEEMR---EEF----------------------LYW-YPVDWRhSGKDLIPnhlTFF-------- 548
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 578 sdiLFFWVA--------RMVMLSyactgklpfktvylhAMVRdAQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnl 649
Cdd:PRK12300 549 ---IFNHVAifpeekwpRGIVVN---------------GFVL-LEGKKMSKSKGNVIPLRKAIE---------------- 593
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 650 ptseikrsiesnskdfptgipECGADALRyglLAYTkqgrnINLDIKRVVAYRHfcnklwnacKFAFGNIEKLKvysest 729
Cdd:PRK12300 594 ---------------------EYGADVVR---LYLT-----SSAELLQDADWRE---------KEVESVRRQLE------ 629
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 730 KFQALSLNNILENYYSYLMWEDFFIIHRLNECITKVSASFKEYLFAE-VVAATYNfwLYELCDIYLELTKlrfkELNNSk 808
Cdd:PRK12300 630 RFYELAKELIEIGGEEELRFIDKWLLSRLNRIIKETTEAMESFQTRDaVQEAFYE--LLNDLRWYLRRVG----EANNK- 702
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 809 safvaaqVLCTCIDFGLRLLHPMIPFVTEELYQRLyqlvsSPERFlsISIAKFPtTLKHSQLNYKKDLEYKIMMRIVSQI 888
Cdd:PRK12300 703 -------VLREVLEIWIRLLAPFTPHLAEELWHKL-----GGEGF--VSLEKWP-EPDESKIDEEAELAEEYVKRLIEDI 767
|
970 980
....*....|....*....|.
gi 209876528 889 RsltSIMEIPNKEKLSITVYI 909
Cdd:PRK12300 768 R---EILKVAKIKPKKVYIYV 785
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
20-397 |
6.41e-20 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 96.05 E-value: 6.41e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 20 ESPMPQSYCPKDVESDWDNLWCSCGFF-SPnfERAKTlSQEEKFVMAL-PPPNVTGcLHIGHTLTSAIQDSLCRYHRMCD 97
Cdd:PLN02563 73 TPAAKRAYPFHEIEPKWQRYWEENRTFrTP--DDVDT-SKPKFYVLDMfPYPSGAG-LHVGHPEGYTATDILARYKRMQG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 98 KEVLWIPGTDHAGI-ATQTVVERillksenksrhdyGRDEFLTrvwdwKKKYGANICTQLRRLGCSFDWTREMFTMDEYM 176
Cdd:PLN02563 149 YNVLHPMGWDAFGLpAEQYAIET-------------GTHPKIT-----TLKNIARFRSQLKSLGFSYDWDREISTTEPEY 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 177 SKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVE--VIE------VQKPTR---LRIPGY-DKTVE--VGILWy 242
Cdd:PLN02563 211 YKWTQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVdgLSErgghpvIRKPMRqwmLKITAYaDRLLEdlDDLDW- 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 243 fsyPLQQKGQQYSW-----------------HFEPENlskipKITVATTRLETMLGDVAVAV---HP------------N 290
Cdd:PLN02563 290 ---PESIKEMQRNWigrsegaeldfsvldgeGKERDE-----KITVYTTRPDTLFGATYLVVapeHPllsslttaeqkeA 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 291 DERYKDLV--------------------GNICLHPFLPErKIRIITDEYVDPEFGTGCVKITPAHDKNDFDVATRYNNKY 350
Cdd:PLN02563 362 VEEYVDAAsrksdlertelqkektgvftGSYAINPATGE-AIPIWVADYVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPI 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 209876528 351 K---DDPSMEQLEFISIFTLDGKMSNNCASFSGIHRFSCRELCEKELSRL 397
Cdd:PLN02563 441 KwvvKPADGNEDDAEKAYTGEGVIVNSSSSGLDINGLSSKEAAKKVIEWL 490
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
64-207 |
6.59e-17 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 83.07 E-value: 6.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 64 MALPPPNvtGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDhagiATQTVVERIllkSENKSRHDYgrdefltrvwD 143
Cdd:cd00812 6 VMFPYPS--GALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFD----AFGLPAENA---AIKIGRDPE----------D 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 209876528 144 WKKKYGANICTQLRRLGCSFDWTREMFTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLR 207
Cdd:cd00812 67 WTEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWCKLLD 130
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
702-889 |
5.50e-16 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 77.21 E-value: 5.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 702 RHFCNKLWNACKFAFGNIEKLKvYSESTKFQALSLNNILenyysylmweDFFIIHRLNECITKVSASFKEYLFAEVVAAT 781
Cdd:cd07961 11 RKVLLPLWNAYRFFVTYANLDG-FDPGKDDDAVASLNVL----------DRWILSRLNSLIKEVTEEMEAYDLYTAVRAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 782 YNFWLyELCDIYLELTKLRFKELNNSKSAFVAAQVLCTCIDFGLRLLHPMIPFVTEELYQRL-YQLVSSPErflSISIAK 860
Cdd:cd07961 80 LEFID-ELTNWYIRRNRKRFWGEEGDDDKLAAYATLYEVLLTLSRLMAPFTPFITEEIYQNLrRELGDAPE---SVHLLD 155
|
170 180 190
....*....|....*....|....*....|.
gi 209876528 861 FPtTLKHSQLNykKDLE--YKIMMRIVSQIR 889
Cdd:cd07961 156 WP-EVDESLID--EELEeaMELVREIVELGR 183
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
60-202 |
5.11e-14 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 74.58 E-value: 5.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 60 EKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERILLKSENKSRHDYGRDEF-- 137
Cdd:cd00818 1 PEFVFHDGPPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGKKDIEKMGIAEFna 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 209876528 138 ------LTRVWDWKKkyganictQLRRLGCSFDWTREMFTMD-EYMSkAVSQAFINLFNQGYIYRGTRLVSW 202
Cdd:cd00818 81 kcrefaLRYVDEQEE--------QFQRLGVWVDWENPYKTMDpEYME-SVWWVFKQLHEKGLLYRGYKVVPW 143
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
65-197 |
2.92e-09 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 59.85 E-value: 2.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 65 ALPPPNvtGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVErillkSENKSRHDYGRD--EFLTRVW 142
Cdd:cd00814 7 ALPYVN--GVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAE-----EEGVTPQELCDKyhEIFKDLF 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 209876528 143 DWkkkyganictqlrrLGCSFD-WTRemfTMDEYMSKAVSQAFINLFNQGYIYRGT 197
Cdd:cd00814 80 KW--------------LNISFDyFIR---TTSPRHKEIVQEFFKKLYENGYIYEGE 118
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
65-197 |
6.92e-09 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 59.74 E-value: 6.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 65 ALPPPNvtGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTD-H----------AGIATQTVVERIllksenksrhdyg 133
Cdd:COG0143 8 AIPYAN--GPPHIGHLYTYIPADILARYQRLRGHDVLFVTGTDeHgtkielaaekEGITPQELVDRI------------- 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 209876528 134 RDEFLTrvwDWKKkyganictqlrrLGCSFD-WTRemfTMDEYmSKAVSQAFIN-LFNQGYIYRGT 197
Cdd:COG0143 73 HAEFKE---LFEK------------LGISFDnFIR---TTSPE-HKELVQEIFQrLYDNGDIYKGE 119
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
65-216 |
1.32e-08 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 58.07 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 65 ALPPPNvtGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVERillksENKSRHDYGrdefltrvwdw 144
Cdd:pfam09334 6 ALPYAN--GPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEK-----EGITPEELV----------- 67
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 209876528 145 kKKYGANICTQLRRLGCSFD-WTRemfTMDEYMSKAVSQAFINLFNQGYIYRGTRLVSWCSYLRTALSDIEVE 216
Cdd:pfam09334 68 -DRYHEIHREDFKKFNISFDdYGR---TTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLPDRYVE 136
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
695-869 |
1.96e-08 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 55.22 E-value: 1.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 695 IKRVV-AYRhfcnKLWNACKFAFGNIEKLKVYSESTKFQALSLnnilenyysylmwEDFFIIHRLNECITKVSASFKEYL 773
Cdd:cd07960 6 LKQVAeAYR----KIRNTFRFLLGNLNDFDPAKDAVPYEELLE-------------LDRYALHRLNELIKEVREAYENYE 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 774 FAEVVAATYNFWLYELCDIYLELTKLR---FKElnNSKSAfVAAQ-VLCTCIDFGLRLLHPMIPFVTEELYQRLyqlvss 849
Cdd:cd07960 69 FHKVYQALNNFCTVDLSAFYLDIIKDRlycDAK--DSLER-RSAQtVLYHILDALLKLLAPILPFTAEEVWEHL------ 139
|
170 180
....*....|....*....|..
gi 209876528 850 PERFLSISI--AKFPTTLKHSQ 869
Cdd:cd07960 140 PGEKKEESVflEDWPELPEEWK 161
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
71-197 |
1.94e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 55.19 E-value: 1.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 71 VTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGiatQTVVERIllKSENKSRHDYGrDEFLTRVWD-WKKkyg 149
Cdd:PRK12267 15 PNGKPHIGHAYTTIAADALARYKRLQGYDVFFLTGTDEHG---QKIQQAA--EKAGKTPQEYV-DEISAGFKElWKK--- 85
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 209876528 150 anictqlrrLGCSFD-WTRemfTMDEYMSKAVSQAFINLFNQGYIYRGT 197
Cdd:PRK12267 86 ---------LDISYDkFIR---TTDERHKKVVQKIFEKLYEQGDIYKGE 122
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
60-196 |
2.47e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 54.50 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 60 EKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGiatqtvvERILLKSENKsrhdyGRDEFlt 139
Cdd:PRK11893 1 KKFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDEHG-------QKIQRKAEEA-----GISPQ-- 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 209876528 140 rvwDWKKKYGANICTQLRRLGCSFD-WTRemfTMDEYMSKAVSQAFINLFNQGYIYRG 196
Cdd:PRK11893 67 ---ELADRNSAAFKRLWEALNISYDdFIR---TTDPRHKEAVQEIFQRLLANGDIYLG 118
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
268-373 |
3.01e-07 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 51.78 E-value: 3.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 268 KITVATTRLETMLGD--VAVAV-HP-------NDERYKDLV-----------------------GNICLHPFlPERKIRI 314
Cdd:pfam13603 22 KIEVFTTRPDTLMGVtfVALAPeHPlveklaeKNPEVAAFIeeckntseiertsetkekegvftGLYAIHPI-TGEKIPI 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 209876528 315 ITDEYVDPEFGTGCVKITPAHDKNDFDVATRYN----------NKYKDDPSMEQLefisiFTLDGKMSN 373
Cdd:pfam13603 101 WIANFVLMEYGTGAVMAVPAHDQRDFEFAKKYNlpikpviqpeDGDLDLDIMTEA-----YTEEGILVN 164
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
535-633 |
3.25e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 54.12 E-value: 3.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 535 VLDTWFSsGLIPF-SSLGWPYKLNPRTGkdDLSTFFPTTLLETGSDILFF----WVArmvMLSyACTGKLPfKTVYLHA- 608
Cdd:PRK11893 221 VIYVWFD-ALTNYlTALGYPDDEELLAE--LFNKYWPADVHLIGKDILRFhavyWPA---FLM-AAGLPLP-KRVFAHGf 292
|
90 100
....*....|....*....|....*
gi 209876528 609 MVRDaqGRKMSKSLGNVIDPLEVIE 633
Cdd:PRK11893 293 LTLD--GEKMSKSLGNVIDPFDLVD 315
|
|
| metG |
TIGR00398 |
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ... |
65-197 |
1.05e-06 |
|
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model appears to recognize the methionyl-tRNA synthetase of every species, including eukaryotic cytosolic and mitochondrial forms. The UPGMA difference tree calculated after search and alignment according to this model shows an unusual deep split between two families of MetG. One family contains forms from the Archaea, yeast cytosol, spirochetes, and E. coli, among others. The other family includes forms from yeast mitochondrion, Synechocystis sp., Bacillus subtilis, the Mycoplasmas, Aquifex aeolicus, and Helicobacter pylori. The E. coli enzyme is homodimeric, although monomeric forms can be prepared that are fully active. Activity of this enzyme in bacteria includes aminoacylation of fMet-tRNA with Met; subsequent formylation of the Met to fMet is catalyzed by a separate enzyme. Note that the protein from Aquifex aeolicus is split into an alpha (large) and beta (small) subunit; this model does not include the C-terminal region corresponding to the beta chain. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273058 [Multi-domain] Cd Length: 530 Bit Score: 52.77 E-value: 1.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 65 ALPPPNvtGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAGIATQTVVErillkSENKSrhdygRDEFLTrvwdw 144
Cdd:TIGR00398 6 ALPYAN--GKPHLGHAYTTILADVYARYKRLRGYEVLFVCGTDEHGTKIELKAE-----QEGLT-----PKELVD----- 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 209876528 145 kkKYGANICTQLRRLGCSFD-WTRemfTMDEYMSKAVSQAFINLFNQGYIYRGT 197
Cdd:TIGR00398 69 --KYHEEFKDDWKWLNISFDrFIR---TTDEEHKEIVQKIFQKLKENGYIYEKE 117
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
464-843 |
2.18e-06 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 51.65 E-value: 2.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 464 WLEN-IQDWCISRQLWWGHRIPayrvcmeniNAEKKPqdIWVAADSeeeaikeVINkfqlklgeftverdtdvldtwfss 542
Cdd:COG0143 218 WLKEgLQDLSISRDFDWGIPVP---------GDPGKV--FYVWFDA-------LIG------------------------ 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 543 gliPFSSL-GWPYKlnpRTGKDDLSTFFPTTLLET----GSDILFF----WVArmvMLSYActG-KLPfKTVYLHAMVrD 612
Cdd:COG0143 256 ---YISATkGYADD---RGLPEDFEKYWPAPDTELvhfiGKDIIRFhaiiWPA---MLMAA--GlPLP-KKVFAHGFL-T 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 613 AQGRKMSKSLGNVIDPLEVIEgisledlnskvkkgnlptseikrsiesnskdfptgipECGADALRYGLLAYTKQGRNIN 692
Cdd:COG0143 323 VEGEKMSKSRGNVIDPDDLLD-------------------------------------RYGPDALRYYLLREVPFGQDGD 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 693 LDIKRVVAyRH---FCNKLwnackfafGNIeklkvYSESTKFQALSLNNILENYYSYLMwEDFFIIHRLNECITKVSASF 769
Cdd:COG0143 366 FSWEDFVA-RVnsdLANDL--------GNL-----ASRTLSMIHKYFDGKVPEPGELTE-ADEELLAEAEAALEEVAEAM 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 770 KEYLFAEVVAATYNFWlyELCDIYLELT---KLRfKELNNSKsafvAAQVLCTCIDfGLR----LLHPMIPFVTEELYQR 842
Cdd:COG0143 431 EAFEFRKALEEIMALA--RAANKYIDETapwKLA-KDEDPER----LATVLYTLLE-ALRilaiLLKPFLPETAEKILEQ 502
|
.
gi 209876528 843 L 843
Cdd:COG0143 503 L 503
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
548-633 |
2.77e-05 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 48.26 E-value: 2.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 548 SSLGWPYKlnprtGKDDLSTFFPTTLLETGSDIL-F---FWVArMVMlsyACTGKLPfKTVYLHA-MVRDaqGRKMSKSL 622
Cdd:PRK12267 237 TALGYGSD-----DDELFKKFWPADVHLVGKDILrFhaiYWPI-MLM---ALGLPLP-KKVFAHGwWLMK--DGKMSKSK 304
|
90
....*....|.
gi 209876528 623 GNVIDPLEVIE 633
Cdd:PRK12267 305 GNVVDPEELVD 315
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
463-633 |
1.65e-04 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 44.83 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 463 HWLEN-IQDWCISRQLW-WGHRIPayrvcmeniNAEKKPQDIWVAAD----SeeeAIKEVINKFqlklGEFTVERDTDVL 536
Cdd:cd00814 173 SWLKEgLKDLSITRDLFdWGIPVP---------LDPGKVIYVWFDALigyiS---ATGYYNEEW----GNSWWWKDGWPE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 537 DTWFssglipfsslgwpyklnprTGKDDL---STFFPTTLLetGSDIlffwvarmvmlsyactgKLPfKTVYLHAMVRdA 613
Cdd:cd00814 237 LVHF-------------------IGKDIIrfhAIYWPAMLL--GAGL-----------------PLP-TRIVAHGYLT-V 276
|
170 180
....*....|....*....|
gi 209876528 614 QGRKMSKSLGNVIDPLEVIE 633
Cdd:cd00814 277 EGKKMSKSRGNVVDPDDLLE 296
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
55-113 |
1.25e-03 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 42.78 E-value: 1.25e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 209876528 55 TLSQEEKFVMALPPPNVTGCLHIGHTLTSAIQDSLCRYHRMCDKEVLWIPGTDHAG--IAT 113
Cdd:PLN02224 64 TVDEADTFVLTTPLYYVNAPPHMGSAYTTIAADSIARFQRLLGKKVIFITGTDEHGekIAT 124
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
598-633 |
1.27e-03 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 42.23 E-value: 1.27e-03
10 20 30
....*....|....*....|....*....|....*.
gi 209876528 598 KLPFKTVYLHAMVRdAQGRKMSKSLGNVIDPLEVIE 633
Cdd:cd00812 257 DEPPKGLIVQGMVL-LEGEKMSKSKGNVVTPDEAIK 291
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
700-843 |
1.86e-03 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 39.13 E-value: 1.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 700 AYRhFCNKLWNackFAFGNIEKLKVYSESTKFQAlslnnilenyysylmwEDFFIIHRLNECITKVSASFKEYLFAEVVA 779
Cdd:cd07958 9 AYR-FLNRVWR---LVTELAEALAAPAAAAELSE----------------EDKELRRKLHKTIKKVTEDIERLRFNTAIA 68
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 209876528 780 AtynfwLYELCDiylELTKLRfkeLNNSKSAFVAAQVLCTcidFgLRLLHPMIPFVTEELYQRL 843
Cdd:cd07958 69 A-----LMELVN---ALYKYK---KKDAQHAAVLREALET---L-VLLLAPFAPHIAEELWEEL 117
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
592-640 |
1.91e-03 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 42.01 E-value: 1.91e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 209876528 592 SYACTGKlPFKTVYLH-AMVRDAqGRKMSKSLGNVIDPLEVIEGISLEDL 640
Cdd:COG0215 241 SEAATGK-PFARYWMHnGFLTVN-GEKMSKSLGNFFTVRDLLKKYDPEVL 288
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
464-640 |
3.23e-03 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 41.12 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 464 WLEN-IQDWCISRQLWWGHRIPayrvcmeniNAEKKPQDIWVAAdseeeaikeVINKFQlklgeFTVERDTDVLDtwfss 542
Cdd:pfam09334 217 WLKEgLKDRAISRDLDWGIPVP---------GAEGKVFYVWLDA---------PIGYIS-----ATKELSGNEEK----- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209876528 543 glipFSSLgWPykLNPRT------GKDDL---STFFPTTLLetGSDIlffwvarmvmlsyactgKLPfKTVYLHAMVrDA 613
Cdd:pfam09334 269 ----WKEW-WP--NDPDTelvhfiGKDIIyfhTIFWPAMLL--GAGY-----------------RLP-TTVFAHGYL-TY 320
|
170 180
....*....|....*....|....*..
gi 209876528 614 QGRKMSKSLGNVIDPLEVIEGISLEDL 640
Cdd:pfam09334 321 EGGKMSKSRGNVVWPSEALDRFPPDAL 347
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
65-120 |
9.75e-03 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 39.75 E-value: 9.75e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 209876528 65 ALPPPNvtGCLHIGHTLTsAIQ-DSLCRYHRMCDKEVLWIPGTD-H----------AGIATQTVVERI 120
Cdd:PRK00133 9 ALPYAN--GPIHLGHLVE-YIQaDIWVRYQRMRGHEVLFVCADDaHgtpimlkaekEGITPEELIARY 73
|
|
| |
