|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03014 |
PLN03014 |
carbonic anhydrase |
1-346 |
0e+00 |
|
carbonic anhydrase
Pssm-ID: 178588 [Multi-domain] Cd Length: 347 Bit Score: 689.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACL-PSSSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGS 79
Cdd:PLN03014 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLpPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 80 DAYEEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVENIKQGFIKFKKEKYETNPALYGELAKGQSP 159
Cdd:PLN03014 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 160 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 239
Cdd:PLN03014 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 240 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFIKGA 319
Cdd:PLN03014 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
|
330 340
....*....|....*....|....*..
gi 297828592 320 FELWGLEFGLSETSSVKDVATILHWKL 346
Cdd:PLN03014 321 FELWGLEFGLSETSSVKDVATILHWKL 347
|
|
| beta_CA_cladeB |
cd00884 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
134-323 |
5.55e-105 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238449 Cd Length: 190 Bit Score: 305.62 E-value: 5.55e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 134 GFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDK-VKYGGVGAAIEYA 212
Cdd:cd00884 1 GFRRFRKEYFPEERELFEKLAKGQSPKALFIACSDSRVVPALITQTQPGELFVVRNVGNLVPPYEPdGGFHGTSAAIEYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 213 VLHLKVENIVVIGHSACGGIKGLMSFPlDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLL 292
Cdd:cd00884 81 VAVLKVEHIVVCGHSDCGGIRALLSPE-DLLDKLPFIGKWLRIAEPAKEVVLAELSHADFDDQLRALEKENVLLSLENLL 159
|
170 180 190
....*....|....*....|....*....|.
gi 297828592 293 TYPFVREGLVKGTLALKGGYYDFIKGAFELW 323
Cdd:cd00884 160 TYPFVRERLEAGTLSLHGWYYDIETGELYAY 190
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
129-315 |
9.25e-70 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 216.57 E-value: 9.25e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 129 ENIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAA 208
Cdd:COG0288 5 KRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYD----PGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 209 IEYAVLHLKVENIVVIGHSACGGIKGLMSfpLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSL 288
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALD--GLELEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQV 158
|
170 180
....*....|....*....|....*..
gi 297828592 289 ANLLTYPFVREGLVKGTLALKGGYYDF 315
Cdd:COG0288 159 ENLRTSPIVREAVAAGKLKVHGWVYDL 185
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
161-315 |
2.67e-61 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 193.11 E-value: 2.67e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 161 YMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSfPL 240
Cdd:pfam00484 1 ALIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYD----LNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALD-AA 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 297828592 241 DGNNSTDFIEDWVKICLPAKSKVISELGDS-AFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDF 315
Cdd:pfam00484 76 GPAELPGFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGKLKIHGWVYDL 151
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
154-314 |
4.72e-58 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 184.63 E-value: 4.72e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 154 AKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIK 233
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYD----DGVLASLEYAVEVLGVKEIVVCGHTDCGAVK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 234 GLMsfpldgNNSTDFIEDWVKICLPAKSKVISELGDSAfedqcgRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYY 313
Cdd:smart00947 77 AAL------DDEPGLIDNWLERIRPARERALEELGDVD------ALEELNVRDQVENLRTSPAIREAVAKGKLKVHGWVY 144
|
.
gi 297828592 314 D 314
Cdd:smart00947 145 D 145
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03014 |
PLN03014 |
carbonic anhydrase |
1-346 |
0e+00 |
|
carbonic anhydrase
Pssm-ID: 178588 [Multi-domain] Cd Length: 347 Bit Score: 689.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACL-PSSSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGS 79
Cdd:PLN03014 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLpPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 80 DAYEEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVENIKQGFIKFKKEKYETNPALYGELAKGQSP 159
Cdd:PLN03014 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 160 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 239
Cdd:PLN03014 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 240 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFIKGA 319
Cdd:PLN03014 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
|
330 340
....*....|....*....|....*..
gi 297828592 320 FELWGLEFGLSETSSVKDVATILHWKL 346
Cdd:PLN03014 321 FELWGLEFGLSETSSVKDVATILHWKL 347
|
|
| PLN03019 |
PLN03019 |
carbonic anhydrase |
77-335 |
2.67e-153 |
|
carbonic anhydrase
Pssm-ID: 166660 Cd Length: 330 Bit Score: 433.80 E-value: 2.67e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 77 MGSDAYEEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVENIKQGFIKFKKEKYETNPALYGELAKG 156
Cdd:PLN03019 73 MGNESYEDAIEALKKLLIEKDDLKDVAAAKVKKITAELQAASSSDSKSFDPVERIKEGFVTFKKEKYETNPALYGELAKG 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 157 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 236
Cdd:PLN03019 153 QSPKYMVFACSDSRVCPSHVLDFHPGDAFVVRNIANMVPPFDKVKYAGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 237 SFPLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEReAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFI 316
Cdd:PLN03019 233 SFPLDGNNSTDFIEDWVKICLPAKSKVLAESESSAFEDQCGRCER-AVNVSLANLLTYPFVREGVVKGTLALKGGYYDFV 311
|
250
....*....|....*....
gi 297828592 317 KGAFELWGLEFGLSETSSV 335
Cdd:PLN03019 312 NGSFELWELQFGISPVHSI 330
|
|
| PLN00416 |
PLN00416 |
carbonate dehydratase |
77-327 |
5.07e-130 |
|
carbonate dehydratase
Pssm-ID: 177809 Cd Length: 258 Bit Score: 372.06 E-value: 5.07e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 77 MGSDAYEEAIEALKKLLIEKEELKTVAAAKVEQITAALQtgtSSDKKAFDPVENIKQGFIKFKKEKYETNPALYGELAKG 156
Cdd:PLN00416 1 MATESYEAAIKGLNDLLSTKADLGNVAAAKIKALTAELK---ELDSSNSDAIERIKTGFTQFKTEKYLKNSTLFNHLAKT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 157 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 236
Cdd:PLN00416 78 QTPKFLVFACSDSRVCPSHILNFQPGEAFVVRNIANMVPPFDQKRHSGVGAAVEYAVVHLKVENILVIGHSCCGGIKGLM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 237 SFPLD-GNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDF 315
Cdd:PLN00416 158 SIEDDaAPTQSDFIENWVKIGASARNKIKEEHKDLSYDDQCNKCEKEAVNVSLGNLLSYPFVRAEVVKNTLAIRGGHYNF 237
|
250
....*....|..
gi 297828592 316 IKGAFELWGLEF 327
Cdd:PLN00416 238 VKGTFDLWELDF 249
|
|
| beta_CA_cladeB |
cd00884 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
134-323 |
5.55e-105 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238449 Cd Length: 190 Bit Score: 305.62 E-value: 5.55e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 134 GFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDK-VKYGGVGAAIEYA 212
Cdd:cd00884 1 GFRRFRKEYFPEERELFEKLAKGQSPKALFIACSDSRVVPALITQTQPGELFVVRNVGNLVPPYEPdGGFHGTSAAIEYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 213 VLHLKVENIVVIGHSACGGIKGLMSFPlDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLL 292
Cdd:cd00884 81 VAVLKVEHIVVCGHSDCGGIRALLSPE-DLLDKLPFIGKWLRIAEPAKEVVLAELSHADFDDQLRALEKENVLLSLENLL 159
|
170 180 190
....*....|....*....|....*....|.
gi 297828592 293 TYPFVREGLVKGTLALKGGYYDFIKGAFELW 323
Cdd:cd00884 160 TYPFVRERLEAGTLSLHGWYYDIETGELYAY 190
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
129-315 |
9.25e-70 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 216.57 E-value: 9.25e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 129 ENIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAA 208
Cdd:COG0288 5 KRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYD----PGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 209 IEYAVLHLKVENIVVIGHSACGGIKGLMSfpLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSL 288
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALD--GLELEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQV 158
|
170 180
....*....|....*....|....*..
gi 297828592 289 ANLLTYPFVREGLVKGTLALKGGYYDF 315
Cdd:COG0288 159 ENLRTSPIVREAVAAGKLKVHGWVYDL 185
|
|
| PLN03006 |
PLN03006 |
carbonate dehydratase |
99-330 |
3.14e-62 |
|
carbonate dehydratase
Pssm-ID: 178583 Cd Length: 301 Bit Score: 200.74 E-value: 3.14e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 99 LKTVAAAKVEQITAAlQTGTSSDKKA-FDPVENIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVL 177
Cdd:PLN03006 53 LQVMASGKTPGLTQE-ANGVAIDRQNnTDVFDDMKQRFLAFKKLKYMDDFEHYKNLADAQAPKFLVIACADSRVCPSAVL 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 178 DFQPGDAFVVRNIANMVPPFDKVKyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFPLDGnNSTDFIEDWVKICL 257
Cdd:PLN03006 132 GFQPGDAFTVRNIANLVPPYESGP-TETKAALEFSVNTLNVENILVIGHSRCGGIQALMKMEDEG-DSRSFIHNWVVVGK 209
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 297828592 258 PAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFIKGAFELWGLEFGLS 330
Cdd:PLN03006 210 KAKESTKAVASNLHFDHQCQHCEKASINHSLERLLGYPWIEEKVRQGSLSLHGGYYNFVDCTFEKWTVDYAAS 282
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
161-315 |
2.67e-61 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 193.11 E-value: 2.67e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 161 YMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSfPL 240
Cdd:pfam00484 1 ALIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYD----LNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALD-AA 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 297828592 241 DGNNSTDFIEDWVKICLPAKSKVISELGDS-AFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDF 315
Cdd:pfam00484 76 GPAELPGFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGKLKIHGWVYDL 151
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
154-314 |
4.72e-58 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 184.63 E-value: 4.72e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 154 AKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIK 233
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYD----DGVLASLEYAVEVLGVKEIVVCGHTDCGAVK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 234 GLMsfpldgNNSTDFIEDWVKICLPAKSKVISELGDSAfedqcgRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYY 313
Cdd:smart00947 77 AAL------DDEPGLIDNWLERIRPARERALEELGDVD------ALEELNVRDQVENLRTSPAIREAVAKGKLKVHGWVY 144
|
.
gi 297828592 314 D 314
Cdd:smart00947 145 D 145
|
|
| PLN02154 |
PLN02154 |
carbonic anhydrase |
123-325 |
2.90e-50 |
|
carbonic anhydrase
Pssm-ID: 215111 Cd Length: 290 Bit Score: 169.54 E-value: 2.90e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 123 KAFDPVENIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPfdkVKY 202
Cdd:PLN02154 71 TSYDFLDEMRHRFLKFKRQKYLPEIEKFKALAIAQSPKVMVIGCADSRVCPSYVLGFQPGEAFTIRNVANLVTP---VQN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 203 G--GVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFPLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCE 280
Cdd:PLN02154 148 GptETNSALEFAVTTLQVENIIVMGHSNCGGIAALMSHQNHQGQHSSLVERWVMNGKAAKLRTQLASSHLSFDEQCRNCE 227
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 297828592 281 REAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFIKGAFELWGL 325
Cdd:PLN02154 228 KESIKDSVMNLITYSWIRDRVKRGEVKIHGCYYNLSDCSLEKWRL 272
|
|
| beta_CA |
cd00382 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
157-323 |
6.82e-47 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238224 [Multi-domain] Cd Length: 119 Bit Score: 154.97 E-value: 6.82e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 157 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGlm 236
Cdd:cd00382 1 QKPKALIIGCSDSRVPPELIFGLGPGDLFVVRNAGNLVPPYD----LDVLASLEYAVEVLGVKHIIVCGHTDCGAVKA-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 237 sfpldgnnstdfiedwvkiclpakskviselgdsafedqcgrCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFI 316
Cdd:cd00382 75 ------------------------------------------LVEENVREQVENLRSHPLIQEAVAPGELKVHGWVYDIE 112
|
....*..
gi 297828592 317 KGAFELW 323
Cdd:cd00382 113 TGKLEVL 119
|
|
| beta_CA_cladeA |
cd00883 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
137-338 |
4.99e-34 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238448 Cd Length: 182 Bit Score: 123.44 E-value: 4.99e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 137 KFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKvkygGVGAAIEYAVLHL 216
Cdd:cd00883 3 AWAEEKKAKDPDFFPRLAKGQTPEYLWIGCSDSRVPENTILGLLPGEVFVHRNIANLVSPTDL----NCLSVLQYAVDVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 217 KVENIVVIGHSACGGIKGLMSFPLDG--NNSTDFIEDWVKiclpaksKVISELgdSAFEDQCGRCER--EAvNV--SLAN 290
Cdd:cd00883 79 KVKHIIVCGHYGCGGVKAALTGKRLGllDNWLRPIRDVYR-------LHAAEL--DALEDEEERVDRlvEL-NVveQVKN 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 297828592 291 LLTYPFVREglvkgtlALKGGyydfikGAFELWGLEFGLsETSSVKDV 338
Cdd:cd00883 149 LCKTPIVQD-------AWKRG------QELEVHGWVYDL-GDGLLRDL 182
|
|
| beta_CA_cladeC |
cd03378 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
129-234 |
1.34e-22 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239473 [Multi-domain] Cd Length: 154 Bit Score: 92.20 E-value: 1.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 129 ENIKQG---FIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPfdkvkygGV 205
Cdd:cd03378 6 ERLKEGnkrFVSGKPLHPDQDLARRRELAKGQKPFAVILSCSDSRVPPEIIFDQGLGDLFVVRVAGNIVDD-------DV 78
|
90 100
....*....|....*....|....*....
gi 297828592 206 GAAIEYAVLHLKVENIVVIGHSACGGIKG 234
Cdd:cd03378 79 LGSLEYAVEVLGVPLVVVLGHESCGAVAA 107
|
|
| PRK10437 |
PRK10437 |
carbonic anhydrase; Provisional |
144-254 |
2.26e-17 |
|
carbonic anhydrase; Provisional
Pssm-ID: 182460 Cd Length: 220 Bit Score: 79.59 E-value: 2.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 144 ETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKvkygGVGAAIEYAVLHLKVENIVV 223
Cdd:PRK10437 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDL----NCLSVVQYAVDVLEVEHIII 95
|
90 100 110
....*....|....*....|....*....|....
gi 297828592 224 IGHSACGGIKGLMSFPLDG--NNSTDFIED-WVK 254
Cdd:PRK10437 96 CGHYGCGGVQAAVENPELGliNNWLLHIRDiWFK 129
|
|
| PRK15219 |
PRK15219 |
carbonic anhydrase; Provisional |
102-234 |
1.46e-08 |
|
carbonic anhydrase; Provisional
Pssm-ID: 237927 [Multi-domain] Cd Length: 245 Bit Score: 54.84 E-value: 1.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297828592 102 VAAAKVEQIT-AALQTGTSSDKKAFDPV-ENIKQGFIKFKkekyETNPALYGELA------KGQSPKYMVFACSDSRVCP 173
Cdd:PRK15219 29 LAGLGVPQISyAASLTKEERDKMTPDQIiESLKQGNKRFR----SGKPAQHDYLAqkrasaAGQYPAAVILSCIDSRAPA 104
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 297828592 174 SHVLDFQPGDAF---VVRNIANmvppfdkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKG 234
Cdd:PRK15219 105 EIILDTGIGETFnsrVAGNISN----------DDLLGSMEFACAVAGAKVVLVMGHTACGAVKG 158
|
|
| beta_CA_cladeD |
cd03379 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
158-230 |
1.16e-07 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239474 Cd Length: 142 Bit Score: 50.33 E-value: 1.16e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 297828592 158 SPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVppfdkvkyggVGAAIEYAVL---HLKVENIVVIGHSACG 230
Cdd:cd03379 2 ARKLAIVTCMDARLDPEKALGLKLGDAKVIRNAGGRV----------TDDAIRSLVVsvyLLGTREIIVIHHTDCG 67
|
|
| |
