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Conserved domains on  [gi|402549369|ref|XP_003888463|]
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hypothetical protein, conserved [Leishmania infantum JPCM5]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
 139-179 1.49e-11

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member cd19510:

Pssm-ID: 476819 [Multi-domain]  Cd Length: 153  Bit Score: 61.60  E-value: 1.49e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 402549369 139 KLDLSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGR 179
Cdd:cd19510  106 RVTFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGR 146
 
Name Accession Description Interval E-value
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 139-179 1.49e-11

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 61.60  E-value: 1.49e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 402549369 139 KLDLSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGR 179
Cdd:cd19510  106 RVTFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGR 146
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 145-180 2.05e-04

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 42.97  E-value: 2.05e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 402549369  145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:TIGR01243 578 LLTEMDGIQELSNVVVIAATNRPDILDPALLRPGRF 613
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 145-180 3.24e-04

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 41.92  E-value: 3.24e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 402549369 145 LLNVLDGVvDMPGRMVVM-ITEHPEWLDPALIRPGRF 180
Cdd:COG1222  203 LLAELDGF-ESRGDVLIIaATNRPDLLDPALLRPGRF 238
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 145-186 1.19e-03

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 40.52  E-value: 1.19e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 402549369 145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRFSVRLRL 186
Cdd:PTZ00361 310 LLNQLDGFDSRGDVKVIMATNRIESLDPALIRPGRIDRKIEF 351
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 142-188 2.92e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 37.19  E-value: 2.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 402549369  142 LSGLLNVLDGVVDMPGR-MVVMITEHPEWLDPALIrpGRFSVRLRLDY 188
Cdd:pfam00004  85 VNQLLTELDGFTSSNSKvIVIAATNRPDKLDPALL--GRFDRIIEFPL 130
 
Name Accession Description Interval E-value
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 139-179 1.49e-11

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 61.60  E-value: 1.49e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 402549369 139 KLDLSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGR 179
Cdd:cd19510  106 RVTFSGLLNALDGVASSEERIVFMTTNHIERLDPALIRPGR 146
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 142-186 7.96e-07

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 48.05  E-value: 7.96e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 402549369 142 LSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRFSVRLRL 186
Cdd:cd19481  114 LNQLLTELDGVNSRSKVLVIAATNRPDLLDPALLRPGRFDEVIEF 158
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 142-180 1.70e-06

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 47.28  E-value: 1.70e-06
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 402549369 142 LSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19511  115 VSQLLTELDGIESLKGVVVIAATNRPDMIDPALLRPGRL 153
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
 145-180 2.98e-06

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 46.72  E-value: 2.98e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 402549369 145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19529  118 LLTELDGLEEMNGVVVIAATNRPDIIDPALLRAGRF 153
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 145-180 1.30e-04

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 41.89  E-value: 1.30e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 402549369 145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19503  124 LLTLMDGMSSRGKVVVIAATNRPDAIDPALRRPGRF 159
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 134-180 1.63e-04

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 41.55  E-value: 1.63e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 402549369 134 GDSKDKLDLSGLLNVLDGVvDMPGRM-VVMITEHPEWLDPALIRPGRF 180
Cdd:cd19502  119 GDREVQRTMLELLNQLDGF-DPRGNIkVIMATNRPDILDPALLRPGRF 165
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 145-180 2.05e-04

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 42.97  E-value: 2.05e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 402549369  145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:TIGR01243 578 LLTEMDGIQELSNVVVIAATNRPDILDPALLRPGRF 613
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 145-180 2.18e-04

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 41.26  E-value: 2.18e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 402549369 145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19526  117 LLTQLDGVEGLDGVYVLAATSRPDLIDPALLRPGRL 152
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 145-180 3.24e-04

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 41.92  E-value: 3.24e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 402549369 145 LLNVLDGVvDMPGRMVVM-ITEHPEWLDPALIRPGRF 180
Cdd:COG1222  203 LLAELDGF-ESRGDVLIIaATNRPDLLDPALLRPGRF 238
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 142-180 5.47e-04

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 39.91  E-value: 5.47e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 402549369 142 LSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19501  127 LNQLLVEMDGFESNTGVIVIAATNRPDVLDPALLRPGRF 165
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 145-186 1.19e-03

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 40.52  E-value: 1.19e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 402549369 145 LLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRFSVRLRL 186
Cdd:PTZ00361 310 LLNQLDGFDSRGDVKVIMATNRIESLDPALIRPGRIDRKIEF 351
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
133-180 1.64e-03

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 40.02  E-value: 1.64e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 402549369 133 LGDSKDKLD--LSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGRF 180
Cdd:PRK10733 264 LGGGHDEREqtLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRF 313
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 142-188 2.92e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 37.19  E-value: 2.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 402549369  142 LSGLLNVLDGVVDMPGR-MVVMITEHPEWLDPALIrpGRFSVRLRLDY 188
Cdd:pfam00004  85 VNQLLTELDGFTSSNSKvIVIAATNRPDKLDPALL--GRFDRIIEFPL 130
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 134-180 3.31e-03

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 37.49  E-value: 3.31e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 402549369 134 GDSKDKLD--LSGLLNVLDGVVDMP-GRMVVMITEHPEWLDPALIRPGRF 180
Cdd:cd19527  105 GDSGGVMDrvVSQLLAELDGMSSSGqDVFVIGATNRPDLLDPALLRPGRF 154
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
 134-179 4.75e-03

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 37.10  E-value: 4.75e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 402549369 134 GDSKDKLdLSGLLNVLDGVVDMPGRMVVMITEHPEWLDPALIRPGR 179
Cdd:cd19528  110 GGAADRV-INQILTEMDGMNTKKNVFIIGATNRPDIIDPAILRPGR 154
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
160-180 8.74e-03

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 37.71  E-value: 8.74e-03
                         10        20
                 ....*....|....*....|...
gi 402549369 160 VVMI--TEHPEWLDPALIRPGRF 180
Cdd:COG0465  281 VIVIaaTNRPDVLDPALLRPGRF 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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