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Conserved domains on  [gi|569005375|ref|XP_006526560|]
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zinc finger protein 236 isoform X5 [Mus musculus]

Protein Classification

COG5048 and zf-H2C2_2 domain-containing protein( domain architecture ID 11473192)

COG5048 and zf-H2C2_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 1.94e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005375 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 1.12e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 569005375  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK 362
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1184-1208 2.61e-06

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 2.61e-06
                           10        20
                   ....*....|....*....|....*
gi 569005375  1184 DLVRHVRIHTGEKPYKCDECGKSFT 1208
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 6.66e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 50.46  E-value: 6.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEgfrtavhcrKHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSL---------PPSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005375 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 1.96e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
FhaB super family cl27105
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1533 2.68e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


The actual alignment was detected with superfamily member COG3210:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 45.91  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 569005375 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISG 1533
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSG 1003
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.88e-03

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.76  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005375  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 1.94e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005375 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 1.12e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 569005375  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK 362
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1184-1208 2.61e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 2.61e-06
                           10        20
                   ....*....|....*....|....*
gi 569005375  1184 DLVRHVRIHTGEKPYKCDECGKSFT 1208
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
984-1009 5.99e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 44.28  E-value: 5.99e-06
                           10        20
                   ....*....|....*....|....*.
gi 569005375   984 HLKQHVRSHTGEKPYKCKLCGRAFVS 1009
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
214-238 6.55e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 6.55e-06
                           10        20
                   ....*....|....*....|....*
gi 569005375   214 LTRHIRIHTGERPFKCSECGKAFNQ 238
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 6.66e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 50.46  E-value: 6.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEgfrtavhcrKHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSL---------PPSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005375 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 1.96e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 657-708 2.21e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.39  E-value: 2.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005375  657 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 708
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1533 2.68e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 45.91  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 569005375 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISG 1533
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSG 1003
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1240-1265 5.40e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 5.40e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375  1240 SLKVHMRLHTGAKPFKCPHCELRFRT 1265
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 201-246 1.73e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 1.73e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 569005375  201 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 246
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.88e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.76  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005375  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1196-1245 4.40e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 4.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005375 1196 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1245
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 537-587 4.91e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.70  E-value: 4.91e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 569005375  537 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 587
Cdd:PHA00733   71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 1.94e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 58.55  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005375 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 1.12e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 569005375  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK 362
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1184-1208 2.61e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 2.61e-06
                           10        20
                   ....*....|....*....|....*
gi 569005375  1184 DLVRHVRIHTGEKPYKCDECGKSFT 1208
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
984-1009 5.99e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 44.28  E-value: 5.99e-06
                           10        20
                   ....*....|....*....|....*.
gi 569005375   984 HLKQHVRSHTGEKPYKCKLCGRAFVS 1009
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
214-238 6.55e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 6.55e-06
                           10        20
                   ....*....|....*....|....*
gi 569005375   214 LTRHIRIHTGERPFKCSECGKAFNQ 238
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 6.66e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 50.46  E-value: 6.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEgfrtavhcrKHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSL---------PPSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005375 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
673-698 1.64e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 1.64e-05
                           10        20
                   ....*....|....*....|....*.
gi 569005375   673 HLKQHIRSHTGEKPFKCSQCGRGFVS 698
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 1.96e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 657-708 2.21e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.39  E-value: 2.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005375  657 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 708
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 199-221 2.27e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 2.27e-04
                           10        20
                   ....*....|....*....|...
gi 569005375   199 YSCPHCGKTFQKPSQLTRHIRIH 221
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1533 2.68e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 45.91  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 569005375 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISG 1533
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSG 1003
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1040-1065 3.54e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 3.54e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375  1040 SLTRHMATHMSMKPYKCPFCEEGFRT 1065
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 685-734 4.71e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 4.71e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005375  685 KPFkCSQCGRGFVSAGVLKAHVRTHTglksFKCLICNGAFTTGGSLRRHM 734
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1240-1265 5.40e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 5.40e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005375  1240 SLKVHMRLHTGAKPFKCPHCELRFRT 1265
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 972-1016 6.01e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 6.01e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 569005375  972 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRAFVSSGVLKSH 1016
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 970-992 1.24e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.66  E-value: 1.24e-03
                           10        20
                   ....*....|....*....|...
gi 569005375   970 YRCDYCNKGFKKSSHLKQHVRSH 992
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 201-246 1.73e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 1.73e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 569005375  201 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 246
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.88e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.76  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005375  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 227-249 2.29e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.89  E-value: 2.29e-03
                           10        20
                   ....*....|....*....|...
gi 569005375   227 FKCSECGKAFNQKGALQTHMIKH 249
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 484-506 2.90e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.51  E-value: 2.90e-03
                           10        20
                   ....*....|....*....|...
gi 569005375   484 HVCPYCTKEFRKPSDLVRHIRIH 506
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 510-558 3.28e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 3.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 569005375  510 KPFkCPQCFRAFAVKSTLTAHIKTHTgikaFKCQYCMKSFSTSGSLKVH 558
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
729-754 4.12e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 4.12e-03
                           10        20
                   ....*....|....*....|....*.
gi 569005375   729 SLRRHMGIHNDLRPYMCPYCQKTFKT 754
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1196-1245 4.40e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 4.40e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005375 1196 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1245
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 537-587 4.91e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.70  E-value: 4.91e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 569005375  537 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 587
Cdd:PHA00733   71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
zf-H2C2_2 pfam13465
Zinc-finger double domain;
527-551 7.28e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 7.28e-03
                           10        20
                   ....*....|....*....|....*
gi 569005375   527 LTAHIKTHTGIKAFKCQYCMKSFST 551
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1026-1048 8.38e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 8.38e-03
                           10        20
                   ....*....|....*....|...
gi 569005375  1026 FSCSICNASFTTNGSLTRHMATH 1048
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
50-320 8.81e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.45  E-value: 8.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375   50 KESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-VCPV--CNKKFSRVASLKAHIMLH--------- 117
Cdd:COG5048    16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPsQCSYsgCDKSFSRPLELSRHLRTHhnnpsdlns 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  118 ----------EKEENLICSECGDEFTLHSQLAIHMEEHRQELANTRAHT-------------CKACKKEFETSPELKEHM 174
Cdd:COG5048    96 kslplsnskaSSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISnlrnnplpgnnssSVNTPQSNSLHPPLPANS 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005375  175 KTHCKVRASGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIH-TGERPFKCSECGKAFNQKGALQTHmIKHTGEK 253
Cdd:COG5048   176 LSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENsSSSLPLTTNSQLSPKSLLSQSPSS-LSSSDSS 254

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569005375  254 PHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT--YNCTECSCVFKSLGSLNTHISKMHMGGPPNSTTS 320
Cdd:COG5048   255 SSASESPRSSLPTASSQSSSPNESDSSSEKGFSlpIKSKQCNISFSRSSPLTRHLRSVNHSGESLKPFS 323
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 994-1064 9.89e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 9.89e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 569005375  994 GEKPYKCKL--CGRAFVSSGVLKSHEKT-HtgvkafscsiCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFR 1064
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYHMLHgH----------QNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYK 409
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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