toll-like receptor 6 isoform X1 [Bos taurus]
toll-like receptor( domain architecture ID 11471523)
toll-like receptor (TLR) is involved in the recognition of microbial pathogens by the innate immune system, which recognize different pathogen-associated molecular patterns
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
TIR | smart00255 | Toll - interleukin 1 - resistance; |
641-784 | 9.67e-38 | |||||
Toll - interleukin 1 - resistance; : Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 137.45 E-value: 9.67e-38
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
35-165 | 2.63e-15 | |||||
Leucine-rich repeat (LRR) protein [Transcription]; : Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.82 E-value: 2.63e-15
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
237-531 | 7.38e-13 | |||||
Leucine-rich repeat (LRR) protein [Transcription]; : Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.12 E-value: 7.38e-13
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LRRCT | smart00082 | Leucine rich repeat C-terminal domain; |
529-582 | 3.68e-07 | |||||
Leucine rich repeat C-terminal domain; : Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 47.42 E-value: 3.68e-07
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Name | Accession | Description | Interval | E-value | ||||||||
TIR | smart00255 | Toll - interleukin 1 - resistance; |
641-784 | 9.67e-38 | ||||||||
Toll - interleukin 1 - resistance; Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 137.45 E-value: 9.67e-38
|
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TIR | pfam01582 | TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
642-774 | 1.82e-20 | ||||||||
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades. Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 88.96 E-value: 1.82e-20
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
35-165 | 2.63e-15 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.82 E-value: 2.63e-15
|
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
237-531 | 7.38e-13 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.12 E-value: 7.38e-13
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LRR_8 | pfam13855 | Leucine rich repeat; |
76-134 | 1.83e-08 | ||||||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.83e-08
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LRRCT | smart00082 | Leucine rich repeat C-terminal domain; |
529-582 | 3.68e-07 | ||||||||
Leucine rich repeat C-terminal domain; Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 47.42 E-value: 3.68e-07
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
55-141 | 9.88e-07 | ||||||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 9.88e-07
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
46-494 | 1.57e-06 | ||||||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 51.77 E-value: 1.57e-06
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
42-138 | 2.00e-06 | ||||||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 51.62 E-value: 2.00e-06
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LRR_8 | pfam13855 | Leucine rich repeat; |
450-507 | 1.56e-04 | ||||||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.20 E-value: 1.56e-04
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LRR_RI | cd00116 | Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
363-498 | 5.47e-03 | ||||||||
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1). Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.65 E-value: 5.47e-03
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Name | Accession | Description | Interval | E-value | ||||||||
TIR | smart00255 | Toll - interleukin 1 - resistance; |
641-784 | 9.67e-38 | ||||||||
Toll - interleukin 1 - resistance; Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 137.45 E-value: 9.67e-38
|
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TIR | pfam01582 | TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
642-774 | 1.82e-20 | ||||||||
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades. Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 88.96 E-value: 1.82e-20
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TIR_2 | pfam13676 | TIR domain; This is a family of Toll-like receptors. |
645-738 | 2.70e-17 | ||||||||
TIR domain; This is a family of Toll-like receptors. Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 78.51 E-value: 2.70e-17
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
35-165 | 2.63e-15 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.82 E-value: 2.63e-15
|
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
237-531 | 7.38e-13 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.12 E-value: 7.38e-13
|
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
356-546 | 1.70e-10 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 63.80 E-value: 1.70e-10
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
55-238 | 1.14e-09 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.10 E-value: 1.14e-09
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LRR_8 | pfam13855 | Leucine rich repeat; |
76-134 | 1.83e-08 | ||||||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.83e-08
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LRR_8 | pfam13855 | Leucine rich repeat; |
52-112 | 3.16e-07 | ||||||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 3.16e-07
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LRRCT | smart00082 | Leucine rich repeat C-terminal domain; |
529-582 | 3.68e-07 | ||||||||
Leucine rich repeat C-terminal domain; Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 47.42 E-value: 3.68e-07
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LRR | COG4886 | Leucine-rich repeat (LRR) protein [Transcription]; |
39-163 | 7.18e-07 | ||||||||
Leucine-rich repeat (LRR) protein [Transcription]; Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 52.24 E-value: 7.18e-07
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
55-141 | 9.88e-07 | ||||||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.55 E-value: 9.88e-07
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
46-494 | 1.57e-06 | ||||||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 51.77 E-value: 1.57e-06
|
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
42-138 | 2.00e-06 | ||||||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 51.62 E-value: 2.00e-06
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
379-507 | 2.99e-06 | ||||||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 50.85 E-value: 2.99e-06
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
353-565 | 1.96e-05 | ||||||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 48.31 E-value: 1.96e-05
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PRK15370 | PRK15370 | type III secretion system effector E3 ubiquitin transferase SlrP; |
378-529 | 3.11e-05 | ||||||||
type III secretion system effector E3 ubiquitin transferase SlrP; Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 47.77 E-value: 3.11e-05
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PLN00113 | PLN00113 | leucine-rich repeat receptor-like protein kinase; Provisional |
53-531 | 1.30e-04 | ||||||||
leucine-rich repeat receptor-like protein kinase; Provisional Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.61 E-value: 1.30e-04
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LRR_8 | pfam13855 | Leucine rich repeat; |
450-507 | 1.56e-04 | ||||||||
Leucine rich repeat; Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.20 E-value: 1.56e-04
|
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PPP1R42 | cd21340 | protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
55-125 | 1.82e-04 | ||||||||
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation. Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 43.62 E-value: 1.82e-04
|
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LRR_RI | cd00116 | Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
43-164 | 7.66e-04 | ||||||||
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1). Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 42.34 E-value: 7.66e-04
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RNA1 | COG5238 | Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
57-159 | 2.12e-03 | ||||||||
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis]; Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 41.31 E-value: 2.12e-03
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LRR_RI | cd00116 | Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
363-498 | 5.47e-03 | ||||||||
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1). Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.65 E-value: 5.47e-03
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Blast search parameters | ||||
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