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Conserved domains on  [gi|767959753|ref|XP_011517652|]
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armadillo repeat-containing protein 3 isoform X4 [Homo sapiens]

Protein Classification

HEAT repeat domain-containing protein( domain architecture ID 11444215)

HEAT repeat domain-containing protein may function as a scaffold, anchoring and/or adaptor protein

CATH:  1.25.10.110
Gene Ontology:  GO:0005515
PubMed:  35552740|10378263
SCOP:  4001283

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03200 super family cl33659
cellulose synthase-interactive protein; Provisional
 203-542 2.88e-10

cellulose synthase-interactive protein; Provisional


The actual alignment was detected with superfamily member PLN03200:

Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 63.97  E-value: 2.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  203 EYPViQLLALKTlgviANDKESRTMLRDNQGLDHLIKILET-----KElndlhiEALAVIAN-CLEDMDTMVQIQQTGGL 276
Cdd:PLN03200  464 EYAV-ALLAILT----DEVDESKWAITAAGGIPPLVQLLETgsqkaKE------DSATVLWNlCCHSEDIRACVESAGAV 532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  277 KKLLSFAENSTiPDIQKNAAKAITKAAYDPENRKLfhEQevekcLVALLGSENDGTKIAASQAISAMCENSGSKDFFN-- 354
Cdd:PLN03200  533 PALLWLLKNGG-PKGQEIAAKTLTKLVRTADAATI--SQ-----LTALLLGDLPESKVHVLDVLGHVLSVASLEDLVReg 604

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  355 ---NQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTnmAMQEPL 431
Cdd:PLN03200  605 saaNDALRTLIQLLSSSKEETQEKAASVLADIFSSRQDLCESLATDEIINPCIKLLTNNTEAVATQSARALA--ALSRSI 682

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  432 RLNIQNHDIMHAIISPL-RSANTVVQSKAALAVTATA---CDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVC 507
Cdd:PLN03200  683 KENRKVSYAAEDAIKPLiKLAKSSSIEVAEQAVCALAnllSDPEVAAEALAEDIILPLTRVLREGTLEGKRNAARALAQL 762

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 767959753  508 -----AGDELTANELCRLGALDILEEVNVSGTRKNKFSEA 542
Cdd:PLN03200  763 lkhfpVDDVLKDSVQCRGTVLALVDLLNSTDLDSSATSEA 802
HEAT COG1413
HEAT repeat [General function prediction only];
68-219 3.94e-06

HEAT repeat [General function prediction only];


:

Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 3.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  68 AVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDvmnsviaqlAPEEEVVIHefASLCLANMSAEytskvqif 147
Cdd:COG1413   17 AVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALK---------DPDPEVRAA--AAEALGRIGDP-------- 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767959753 148 ehGGLEPLIRLLSSPDPDVKKNSMECIynlvqdfqcrAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIA 219
Cdd:COG1413   78 --EAVPALIAALKDEDPEVRRAAAEAL----------GRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
 
Name Accession Description Interval E-value
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 203-542 2.88e-10

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 63.97  E-value: 2.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  203 EYPViQLLALKTlgviANDKESRTMLRDNQGLDHLIKILET-----KElndlhiEALAVIAN-CLEDMDTMVQIQQTGGL 276
Cdd:PLN03200  464 EYAV-ALLAILT----DEVDESKWAITAAGGIPPLVQLLETgsqkaKE------DSATVLWNlCCHSEDIRACVESAGAV 532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  277 KKLLSFAENSTiPDIQKNAAKAITKAAYDPENRKLfhEQevekcLVALLGSENDGTKIAASQAISAMCENSGSKDFFN-- 354
Cdd:PLN03200  533 PALLWLLKNGG-PKGQEIAAKTLTKLVRTADAATI--SQ-----LTALLLGDLPESKVHVLDVLGHVLSVASLEDLVReg 604

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  355 ---NQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTnmAMQEPL 431
Cdd:PLN03200  605 saaNDALRTLIQLLSSSKEETQEKAASVLADIFSSRQDLCESLATDEIINPCIKLLTNNTEAVATQSARALA--ALSRSI 682

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  432 RLNIQNHDIMHAIISPL-RSANTVVQSKAALAVTATA---CDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVC 507
Cdd:PLN03200  683 KENRKVSYAAEDAIKPLiKLAKSSSIEVAEQAVCALAnllSDPEVAAEALAEDIILPLTRVLREGTLEGKRNAARALAQL 762

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 767959753  508 -----AGDELTANELCRLGALDILEEVNVSGTRKNKFSEA 542
Cdd:PLN03200  763 lkhfpVDDVLKDSVQCRGTVLALVDLLNSTDLDSSATSEA 802
HEAT COG1413
HEAT repeat [General function prediction only];
68-219 3.94e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 3.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  68 AVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDvmnsviaqlAPEEEVVIHefASLCLANMSAEytskvqif 147
Cdd:COG1413   17 AVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALK---------DPDPEVRAA--AAEALGRIGDP-------- 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767959753 148 ehGGLEPLIRLLSSPDPDVKKNSMECIynlvqdfqcrAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIA 219
Cdd:COG1413   78 --EAVPALIAALKDEDPEVRRAAAEAL----------GRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 469-504 1.25e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.42  E-value: 1.25e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 767959753   469 DVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAV 504
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 469-504 1.06e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.75  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767959753  469 DVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAV 504
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWAL 36
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 143-178 1.65e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.36  E-value: 1.65e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767959753  143 KVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLV 178
Cdd:pfam00514   5 KQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT COG1413
HEAT repeat [General function prediction only];
358-503 3.55e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 358 IPQLIQLLKSDNEEVREAAALALANLttcnpananaaAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRlniqn 437
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARALGRL-----------GDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAVP----- 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767959753 438 hdimhAIISPLRSANTVVQSKAALAVtatacdvearTELRNSGGLEPLVELLRSKNDEVRKHASWA 503
Cdd:COG1413   82 -----ALIAALKDEDPEVRRAAAEAL----------GRLGDPAAVPALLEALKDPDWEVRRAAARA 132
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 57-96 1.78e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 1.78e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 767959753    57 EENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILAS 96
Cdd:smart00185   2 DENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 203-542 2.88e-10

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 63.97  E-value: 2.88e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  203 EYPViQLLALKTlgviANDKESRTMLRDNQGLDHLIKILET-----KElndlhiEALAVIAN-CLEDMDTMVQIQQTGGL 276
Cdd:PLN03200  464 EYAV-ALLAILT----DEVDESKWAITAAGGIPPLVQLLETgsqkaKE------DSATVLWNlCCHSEDIRACVESAGAV 532

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  277 KKLLSFAENSTiPDIQKNAAKAITKAAYDPENRKLfhEQevekcLVALLGSENDGTKIAASQAISAMCENSGSKDFFN-- 354
Cdd:PLN03200  533 PALLWLLKNGG-PKGQEIAAKTLTKLVRTADAATI--SQ-----LTALLLGDLPESKVHVLDVLGHVLSVASLEDLVReg 604

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  355 ---NQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTnmAMQEPL 431
Cdd:PLN03200  605 saaNDALRTLIQLLSSSKEETQEKAASVLADIFSSRQDLCESLATDEIINPCIKLLTNNTEAVATQSARALA--ALSRSI 682

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  432 RLNIQNHDIMHAIISPL-RSANTVVQSKAALAVTATA---CDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVC 507
Cdd:PLN03200  683 KENRKVSYAAEDAIKPLiKLAKSSSIEVAEQAVCALAnllSDPEVAAEALAEDIILPLTRVLREGTLEGKRNAARALAQL 762

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 767959753  508 -----AGDELTANELCRLGALDILEEVNVSGTRKNKFSEA 542
Cdd:PLN03200  763 lkhfpVDDVLKDSVQCRGTVLALVDLLNSTDLDSSATSEA 802
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 321-487 3.82e-06

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 50.49  E-value: 3.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  321 LVALLGSENDGTKIAASQAISA-----MCENSGSKDFFNNQGIPQLIQLLKSDNEE---VREAAALALANLTTCNPANAN 392
Cdd:PLN03200  104 LLSLLKSGSAEAQKAAAEAIYAvssggLSDHVGSKIFSTEGVVPSLWDQLQPGNKQdkvVEGLLTGALRNLCGSTDGFWS 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  393 AAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQ-EPLRLNIQNHDIMHAIISPLRSANTV-VQSKAALAVTA-TACD 469
Cdd:PLN03200  184 ATLEAGGVDILVKLLSSGNSDAQANAASLLARLMMAfESSISKVLDAGAVKQLLKLLGQGNEVsVRAEAAGALEAlSSQS 263

                         170
                  ....*....|....*...
gi 767959753  470 VEARTELRNSGGLEPLVE 487
Cdd:PLN03200  264 KEAKQAIADAGGIPALIN 281
HEAT COG1413
HEAT repeat [General function prediction only];
68-219 3.94e-06

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 46.93  E-value: 3.94e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  68 AVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDvmnsviaqlAPEEEVVIHefASLCLANMSAEytskvqif 147
Cdd:COG1413   17 AVPALIAALADEDPDVRAAAARALGRLGDPRAVPALLEALK---------DPDPEVRAA--AAEALGRIGDP-------- 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767959753 148 ehGGLEPLIRLLSSPDPDVKKNSMECIynlvqdfqcrAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIA 219
Cdd:COG1413   78 --EAVPALIAALKDEDPEVRRAAAEAL----------GRLGDPAAVPALLEALKDPDWEVRRAAARALGRLG 137
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 469-504 1.25e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 42.42  E-value: 1.25e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 767959753   469 DVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAV 504
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWAL 36
SRP1 COG5064
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
24-265 3.27e-05

Karyopherin (importin) alpha [Intracellular trafficking and secretion];


Pssm-ID: 227396 [Multi-domain]  Cd Length: 526  Bit Score: 47.19  E-value: 3.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  24 SKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNAT-MIFGILASNNDVKK 102
Cdd:COG5064  242 SQALPILAKLIYSRDPEVLVDACWAISYLSDGPNEKIQAVLDVGIPGRLVELLSHESAKIQTPALrSVGNIVTGSDDQTQ 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 103 LLRELDVMNSVIAQLAPEEEVVIHEfASLCLANMSAEYTSKVQ-IFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDF 181
Cdd:COG5064  322 VIINCGALKAFRSLLSSPKENIRKE-ACWTISNITAGNTEQIQaVIDANLIPPLIHLLSSAEYKIKKEACWAISNATSGG 400

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 182 QCRAK----LQELNAIPPILDLLK---SEYPVIQLLALKT-LGVIANDKESR--------TMLRDNQGLDhLIKILETKE 245
Cdd:COG5064  401 LNRPDiiryLVSQGFIKPLCDLLDvvdNKIIEVALDAIENiLKVGEQDRLRYgkniniyaVYVEKAGGMD-AIHGLQDSV 479

                        250       260
                 ....*....|....*....|
gi 767959753 246 LNDLHIEALAVIANCLEDMD 265
Cdd:COG5064  480 NRTIYDKAYSIIEKFFGEED 499
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 469-504 1.06e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.75  E-value: 1.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767959753  469 DVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAV 504
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWAL 36
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 143-178 1.65e-04

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 39.36  E-value: 1.65e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 767959753  143 KVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLV 178
Cdd:pfam00514   5 KQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
HEAT COG1413
HEAT repeat [General function prediction only];
358-503 3.55e-04

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 41.15  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 358 IPQLIQLLKSDNEEVREAAALALANLttcnpananaaAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRlniqn 437
Cdd:COG1413   18 VPALIAALADEDPDVRAAAARALGRL-----------GDPRAVPALLEALKDPDPEVRAAAAEALGRIGDPEAVP----- 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767959753 438 hdimhAIISPLRSANTVVQSKAALAVtatacdvearTELRNSGGLEPLVELLRSKNDEVRKHASWA 503
Cdd:COG1413   82 -----ALIAALKDEDPEVRRAAAEAL----------GRLGDPAAVPALLEALKDPDWEVRRAAARA 132
HEAT COG1413
HEAT repeat [General function prediction only];
185-343 1.02e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 40.00  E-value: 1.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 185 AKLQELNAIPPILDLLKSEYPVIQLLALKTLGviandkesrtMLRDNQGLDHLIKILETKelnDLHIEALAVIAncledm 264
Cdd:COG1413   10 GRLGDPAAVPALIAALADEDPDVRAAAARALG----------RLGDPRAVPALLEALKDP---DPEVRAAAAEA------ 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767959753 265 dtMVQIQQTGGLKKLLSFAENSTiPDIQKNAAKAITKaaydpenrklFHEQEVEKCLVALLGSENDGTKIAASQAISAM 343
Cdd:COG1413   71 --LGRIGDPEAVPALIAALKDED-PEVRRAAAEALGR----------LGDPAAVPALLEALKDPDWEVRRAAARALGRL 136
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 57-96 1.78e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 36.64  E-value: 1.78e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 767959753    57 EENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILAS 96
Cdd:smart00185   2 DENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 148-530 2.57e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 41.24  E-value: 2.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  148 EHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQ-CRAKLQELNAIPPILDLLKSEYPVI----QLLALKTLgvIANDK 222
Cdd:PLN03200  187 EAGGVDILVKLLSSGNSDAQANAASLLARLMMAFEsSISKVLDAGAVKQLLKLLGQGNEVSvraeAAGALEAL--SSQSK 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  223 ESRTMLRDNQGLDHLIK--ILETKE-LNDLHIEALAVIANCledmdTMVQIqqTGGLKKL-LSFAENSTIPDIQKNAAKA 298
Cdd:PLN03200  265 EAKQAIADAGGIPALINatVAPSKEfMQGEFAQALQENAMG-----ALANI--CGGMSALiLYLGELSESPRSPAPIADT 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  299 ITKAAY----------------------------DPENRKLFHEQEVE---------------------KCLVALLGSEN 329
Cdd:PLN03200  338 LGALAYalmvfdssaestrafdptvieqilvkllKPRDTKLVQERIIEalaslygnaylsrklnhaeakKVLVGLITMAT 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  330 DGTKIAASQAISAMCENSGS--KDFFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLL 407
Cdd:PLN03200  418 ADVQEELIRALSSLCCGKGGlwEALGGREGVQLLISLLGLSSEQQQEYAVALLAILTDEVDESKWAITAAGGIPPLVQLL 497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  408 SSKRDGAIANAATVLTNMAMQ-EPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEART------------ 474
Cdd:PLN03200  498 ETGSQKAKEDSATVLWNLCCHsEDIRACVESAGAVPALLWLLKNGGPKGQEIAAKTLTKLVRTADAATisqltalllgdl 577

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  475 ---------------------ELRNSG-----GLEPLVELLRSKNDEVRKHASwavMVCAGDELTANELCrlGALDILEE 528
Cdd:PLN03200  578 peskvhvldvlghvlsvasleDLVREGsaandALRTLIQLLSSSKEETQEKAA---SVLADIFSSRQDLC--ESLATDEI 652


                  ..
gi 767959753  529 VN 530
Cdd:PLN03200  653 IN 654
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 155-362 3.18e-03

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 40.86  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  155 LIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIandkeSRTMLRDNQGl 234
Cdd:PLN03200   63 LVSLLRSGTLGAKVNAAAVLGVLCKEEDLRVKVLLGGCIPPLLSLLKSGSAEAQKAAAEAIYAV-----SSGGLSDHVG- 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  235 dhlIKILETKelndlhiealAVIANCLEDM------DTMVQIQQTGGLKKLLSFAEN-------------------STIP 289
Cdd:PLN03200  137 ---SKIFSTE----------GVVPSLWDQLqpgnkqDKVVEGLLTGALRNLCGSTDGfwsatleaggvdilvkllsSGNS 203

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 767959753  290 DIQKNAAK--AITKAAYDPENRKLFHeQEVEKCLVALLGSEND----GTKIAASQAISAMCENSgSKDFFNNQGIPQLI 362
Cdd:PLN03200  204 DAQANAASllARLMMAFESSISKVLD-AGAVKQLLKLLGQGNEvsvrAEAAGALEALSSQSKEA-KQAIADAGGIPALI 280
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 145-179 5.31e-03

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 35.10  E-value: 5.31e-03
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 767959753   145 QIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQ 179
Cdd:smart00185   7 AVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
COG5096 COG5096
Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular ...
 71-371 8.64e-03

Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 227427 [Multi-domain]  Cd Length: 757  Bit Score: 39.33  E-value: 8.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753  71 PLTKLLTHEDKIVrrnATMIFGILASNNDVKKLlrelDVMNSVIAQLAPEEevvihefaslclaNMSaEYTSKVqifehg 150
Cdd:COG5096    8 KDSIRKARNADSV---AALSSGRLESSNDYKKI----DAMKKIIAQMSLGE-------------DMS-SLFPDV------ 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 151 gleplIRLLSSPDPDVKKnsmECIYNLVQDFQCRAKLQELnAIPPILDLLKSEYPVIQLLALKTLgviandkesrTMLRD 230
Cdd:COG5096   61 -----IKNVATRDVELKR---LLYLYLERYAKLKPELALL-AVNTIQKDLQDPNEEIRGFALRTL----------SLLRV 121

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767959753 231 NQGLDHLIKiletkelndlhiealaVIANCLEDMDTMVqiqqtgglkkllsfaenstipdiQKNAAKAITKaaYDPENRK 310
Cdd:COG5096  122 KELLGNIID----------------PIKKLLTDPHAYV-----------------------RKTAALAVAK--LYRLDKD 160

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767959753 311 LFHEQEVEKCLVALLgSENDGTKIAASQAISAMCENSGSKDFFNN--QGIPQLIQLLKSDNEE 371
Cdd:COG5096  161 LYHELGLIDILKELV-ADSDPIVIANALASLAEIDPELAHGYSLEviLRIPQLDLLSLSVSTE 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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