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Conserved domains on  [gi|767965920|ref|XP_011518416|]
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GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform X1 [Homo sapiens]

Protein Classification

ADP-ribosyltransferase family protein; tetratricopeptide repeat protein( domain architecture ID 10471557)

ADP-ribosyltransferase family protein similar to mono (ADP-ribosyl) transferases, which exist in vertebrates and transfer ADP-ribose to arginine| tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ART pfam01129
NAD:arginine ADP-ribosyltransferase;
39-274 5.77e-118

NAD:arginine ADP-ribosyltransferase;


:

Pssm-ID: 279473  Cd Length: 222  Bit Score: 339.04  E-value: 5.77e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920   39 LDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPewslsptrpspPPLGFRDEHGVAL 118
Cdd:pfam01129   1 LDMAPNAFDDQYLGCVDRMEAKAPLLLKEEFAMNQALAVSWEQAKKRWQERKALLS-----------LPMGFKDDHGIAL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920  119 LAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGqrPPRCHQVFRGVHGLRFRPAGPRATVRLG 198
Cdd:pfam01129  70 LAYTSSSPLYRLFNEAVREAGRSREDYIGNFHFKALHFYLTRALQLLRQS--YQPCHQVYRGVKGTRFTYTGPGKSVRFG 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767965920  199 GFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRlAQGPARIYLRALGKHST 274
Cdd:pfam01129 148 QFTSSSLHKQVAEFFGQDTLFIIKTCLGVPIKPFSFFPSEDEVLIPPFEVFQVTGFSR-TQGYNHIDLDSIGKTSS 222
 
Name Accession Description Interval E-value
ART pfam01129
NAD:arginine ADP-ribosyltransferase;
39-274 5.77e-118

NAD:arginine ADP-ribosyltransferase;


Pssm-ID: 279473  Cd Length: 222  Bit Score: 339.04  E-value: 5.77e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920   39 LDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPewslsptrpspPPLGFRDEHGVAL 118
Cdd:pfam01129   1 LDMAPNAFDDQYLGCVDRMEAKAPLLLKEEFAMNQALAVSWEQAKKRWQERKALLS-----------LPMGFKDDHGIAL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920  119 LAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGqrPPRCHQVFRGVHGLRFRPAGPRATVRLG 198
Cdd:pfam01129  70 LAYTSSSPLYRLFNEAVREAGRSREDYIGNFHFKALHFYLTRALQLLRQS--YQPCHQVYRGVKGTRFTYTGPGKSVRFG 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767965920  199 GFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRlAQGPARIYLRALGKHST 274
Cdd:pfam01129 148 QFTSSSLHKQVAEFFGQDTLFIIKTCLGVPIKPFSFFPSEDEVLIPPFEVFQVTGFSR-TQGYNHIDLDSIGKTSS 222
 
Name Accession Description Interval E-value
ART pfam01129
NAD:arginine ADP-ribosyltransferase;
39-274 5.77e-118

NAD:arginine ADP-ribosyltransferase;


Pssm-ID: 279473  Cd Length: 222  Bit Score: 339.04  E-value: 5.77e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920   39 LDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPewslsptrpspPPLGFRDEHGVAL 118
Cdd:pfam01129   1 LDMAPNAFDDQYLGCVDRMEAKAPLLLKEEFAMNQALAVSWEQAKKRWQERKALLS-----------LPMGFKDDHGIAL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767965920  119 LAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGqrPPRCHQVFRGVHGLRFRPAGPRATVRLG 198
Cdd:pfam01129  70 LAYTSSSPLYRLFNEAVREAGRSREDYIGNFHFKALHFYLTRALQLLRQS--YQPCHQVYRGVKGTRFTYTGPGKSVRFG 147

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767965920  199 GFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRlAQGPARIYLRALGKHST 274
Cdd:pfam01129 148 QFTSSSLHKQVAEFFGQDTLFIIKTCLGVPIKPFSFFPSEDEVLIPPFEVFQVTGFSR-TQGYNHIDLDSIGKTSS 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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