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Conserved domains on  [gi|1034606258|ref|XP_016881803|]
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zinc finger protein 418 isoform X8 [Homo sapiens]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-638 4.42e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.49  E-value: 4.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 250 KRPYECGECGKSFSHKGSLVQHQRVHTGERPYECG--ECGKSFSQNGTLIKHQRVHTGERPYECE-ECGKCFTQKGNLIQ 326
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSL 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 327 HQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSF----------------------SRKGHLRNHQ 384
Cdd:COG5048   111 SSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSvntpqsnslhpplpanslskdpSSNLSLLISS 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 385 RGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRG------KSHLIEHQRVHTGERPYECNECGKSF 458
Cdd:COG5048   191 NVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKsllsqsPSSLSSSDSSSSASESPRSSLPTASS 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 459 QDSSGFRVHQRVHTG-EKPFECSECGKSFPQSCSLLRHRR--VHTGE--RPYECGE--CGKSFHQSSSLLRHQKTHTAER 531
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 532 PYEC--RECGKFFSSLLEHRRVhtgerpyecrecgktftrrsAHFKHQRLHTRGKPYEC--SECGKSFAETFSLTEHRRV 607
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNNEPP--------------------QSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIIT 410
                         410       420       430
                  ....*....|....*....|....*....|...
gi 1034606258 608 HTGERPYEC--SECGKSFHRSSSLLRHQRVHTE 638
Cdd:COG5048   411 HLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTN 443
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-638 4.42e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.49  E-value: 4.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 250 KRPYECGECGKSFSHKGSLVQHQRVHTGERPYECG--ECGKSFSQNGTLIKHQRVHTGERPYECE-ECGKCFTQKGNLIQ 326
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSL 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 327 HQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSF----------------------SRKGHLRNHQ 384
Cdd:COG5048   111 SSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSvntpqsnslhpplpanslskdpSSNLSLLISS 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 385 RGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRG------KSHLIEHQRVHTGERPYECNECGKSF 458
Cdd:COG5048   191 NVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKsllsqsPSSLSSSDSSSSASESPRSSLPTASS 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 459 QDSSGFRVHQRVHTG-EKPFECSECGKSFPQSCSLLRHRR--VHTGE--RPYECGE--CGKSFHQSSSLLRHQKTHTAER 531
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 532 PYEC--RECGKFFSSLLEHRRVhtgerpyecrecgktftrrsAHFKHQRLHTRGKPYEC--SECGKSFAETFSLTEHRRV 607
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNNEPP--------------------QSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIIT 410
                         410       420       430
                  ....*....|....*....|....*....|...
gi 1034606258 608 HTGERPYEC--SECGKSFHRSSSLLRHQRVHTE 638
Cdd:COG5048   411 HLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTN 443
zf-H2C2_2 pfam13465
Zinc-finger double domain;
379-404 3.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*.
gi 1034606258 379 HLRNHQRGHTGERPYECGECGKSFSR 404
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
419-471 7.33e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.00  E-value: 7.33e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034606258 419 RPYeCRECRKLFRGKSHLIEHQRVHTgerpYECNECGKSFQDSSGFRVH-QRVH 471
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHcLQVH 49
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
250-638 4.42e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 65.49  E-value: 4.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 250 KRPYECGECGKSFSHKGSLVQHQRVHTGERPYECG--ECGKSFSQNGTLIKHQRVHTGERPYECE-ECGKCFTQKGNLIQ 326
Cdd:COG5048    31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSL 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 327 HQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSF----------------------SRKGHLRNHQ 384
Cdd:COG5048   111 SSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSvntpqsnslhpplpanslskdpSSNLSLLISS 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 385 RGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRG------KSHLIEHQRVHTGERPYECNECGKSF 458
Cdd:COG5048   191 NVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKsllsqsPSSLSSSDSSSSASESPRSSLPTASS 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 459 QDSSGFRVHQRVHTG-EKPFECSECGKSFPQSCSLLRHRR--VHTGE--RPYECGE--CGKSFHQSSSLLRHQKTHTAER 531
Cdd:COG5048   271 QSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSIS 350
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 532 PYEC--RECGKFFSSLLEHRRVhtgerpyecrecgktftrrsAHFKHQRLHTRGKPYEC--SECGKSFAETFSLTEHRRV 607
Cdd:COG5048   351 PAKEklLNSSSKFSPLLNNEPP--------------------QSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIIT 410
                         410       420       430
                  ....*....|....*....|....*....|...
gi 1034606258 608 HTGERPYEC--SECGKSFHRSSSLLRHQRVHTE 638
Cdd:COG5048   411 HLSFRPYNCknPPCSKSFNRHYNLIPHKKIHTN 443
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
364-550 1.01e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.70  E-value: 1.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 364 PYECGECGKSFSRKGHLRNHQRG--HTGE--RPYECGE--CGKSFSRKGNLIQHQRSHTGERPYECRECRklfRGKSHLI 437
Cdd:COG5048   289 PIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLN---SSSKFSP 365
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 438 ehqrvhtgerpyecnecgKSFQDSSGFRVHQRVHTGEKPFEC--SECGKSFPQSCSLLRHRRVHTGERPYEC--GECGKS 513
Cdd:COG5048   366 ------------------LLNNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCSKS 427
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1034606258 514 FHQSSSLLRHQKTHTAERPYECRECGKFFSSLLEHRR 550
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
363-643 2.46e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 2.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 363 RPYECGECGKSFSRKGHLRNHQRGHTGERPYECG--ECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGK--SHLIE 438
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSSLS 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 439 HQRVHTgerPYECNECGKSFQDSSGFR----VHQRVHTGEKPFE-CSECGKSFPQS-------------------CSLLR 494
Cdd:COG5048   112 SSSSNS---NDNNLLSSHSLPPSSRDPqlpdLLSISNLRNNPLPgNNSSSVNTPQSnslhpplpanslskdpssnLSLLI 188
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 495 HRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTF-----TR 569
Cdd:COG5048   189 SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrsslpTA 268
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034606258 570 RSAHFKHQRLHT-----RGKPYECSECGKSFAETFSLTEHRR--VHTGE--RPYECSE--CGKSFHRSSSLLRHQRVHTE 638
Cdd:COG5048   269 SSQSSSPNESDSssekgFSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTS 348

                  ....*
gi 1034606258 639 RSPYK 643
Cdd:COG5048   349 ISPAK 353
zf-H2C2_2 pfam13465
Zinc-finger double domain;
379-404 3.44e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*.
gi 1034606258 379 HLRNHQRGHTGERPYECGECGKSFSR 404
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
267-292 4.80e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 4.80e-03
                          10        20
                  ....*....|....*....|....*.
gi 1034606258 267 SLVQHQRVHTGERPYECGECGKSFSQ 292
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
435-458 6.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 6.51e-03
                          10        20
                  ....*....|....*....|....
gi 1034606258 435 HLIEHQRVHTGERPYECNECGKSF 458
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
419-471 7.33e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.00  E-value: 7.33e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034606258 419 RPYeCRECRKLFRGKSHLIEHQRVHTgerpYECNECGKSFQDSSGFRVH-QRVH 471
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHcLQVH 49
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
393-415 7.73e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.20  E-value: 7.73e-03
                          10        20
                  ....*....|....*....|...
gi 1034606258 393 YECGECGKSFSRKGNLIQHQRSH 415
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
239-264 7.77e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 7.77e-03
                          10        20
                  ....*....|....*....|....*.
gi 1034606258 239 SLVQHQRVHTGKRPYECGECGKSFSH 264
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
544-569 7.85e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 7.85e-03
                          10        20
                  ....*....|....*....|....*.
gi 1034606258 544 SLLEHRRVHTGERPYECRECGKTFTR 569
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
296-320 7.93e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 7.93e-03
                          10        20
                  ....*....|....*....|....*
gi 1034606258 296 LIKHQRVHTGERPYECEECGKCFTQ 320
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
491-514 9.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 9.84e-03
                          10        20
                  ....*....|....*....|....
gi 1034606258 491 SLLRHRRVHTGERPYECGECGKSF 514
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
464-486 9.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 9.84e-03
                          10        20
                  ....*....|....*....|...
gi 1034606258 464 FRVHQRVHTGEKPFECSECGKSF 486
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSF 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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