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Conserved domains on  [gi|1034608939|ref|XP_016882620|]
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protein lin-7 homolog B isoform X2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
L27 smart00569
domain in receptor targeting proteins Lin-2 and Lin-7;
15-52 1.21e-08

domain in receptor targeting proteins Lin-2 and Lin-7;


:

Pssm-ID: 197794  Cd Length: 53  Bit Score: 47.12  E-value: 1.21e-08
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1034608939   15 SRAVELLERLQRSGElPPQKLQALQRVLQSRFCSAIRE 52
Cdd:smart00569   1 QRLLELLEELQSLLS-PSEDLQELRRLLQSPHLQALLK 37
 
Name Accession Description Interval E-value
L27 smart00569
domain in receptor targeting proteins Lin-2 and Lin-7;
15-52 1.21e-08

domain in receptor targeting proteins Lin-2 and Lin-7;


Pssm-ID: 197794  Cd Length: 53  Bit Score: 47.12  E-value: 1.21e-08
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1034608939   15 SRAVELLERLQRSGElPPQKLQALQRVLQSRFCSAIRE 52
Cdd:smart00569   1 QRLLELLEELQSLLS-PSEDLQELRRLLQSPHLQALLK 37
L27 pfam02828
L27 domain; The L27 domain is found in receptor targeting proteins Lin-2 and Lin-7.
 14-52 1.38e-08

L27 domain; The L27 domain is found in receptor targeting proteins Lin-2 and Lin-7.


Pssm-ID: 460717  Cd Length: 52  Bit Score: 47.04  E-value: 1.38e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1034608939  14 VSRAVELLERLQRSGElPPQKLQALQRVLQSRFCSAIRE 52
Cdd:pfam02828   1 VELVLELLEDLQPLSE-ASEDLAELQKLLQSPHLQALLE 38
 
Name Accession Description Interval E-value
L27 smart00569
domain in receptor targeting proteins Lin-2 and Lin-7;
15-52 1.21e-08

domain in receptor targeting proteins Lin-2 and Lin-7;


Pssm-ID: 197794  Cd Length: 53  Bit Score: 47.12  E-value: 1.21e-08
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 1034608939   15 SRAVELLERLQRSGElPPQKLQALQRVLQSRFCSAIRE 52
Cdd:smart00569   1 QRLLELLEELQSLLS-PSEDLQELRRLLQSPHLQALLK 37
L27 pfam02828
L27 domain; The L27 domain is found in receptor targeting proteins Lin-2 and Lin-7.
 14-52 1.38e-08

L27 domain; The L27 domain is found in receptor targeting proteins Lin-2 and Lin-7.


Pssm-ID: 460717  Cd Length: 52  Bit Score: 47.04  E-value: 1.38e-08
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1034608939  14 VSRAVELLERLQRSGElPPQKLQALQRVLQSRFCSAIRE 52
Cdd:pfam02828   1 VELVLELLEDLQPLSE-ASEDLAELQKLLQSPHLQALLE 38
Leuk-A4-hydro_C pfam09127
Leukotriene A4 hydrolase, C-terminal; Members of this family adopt a structure consisting of ...
 18-64 8.46e-03

Leukotriene A4 hydrolase, C-terminal; Members of this family adopt a structure consisting of two layers of parallel alpha-helices, five in the inner layer and four in the outer, arranged in an antiparallel manner, with perpendicular loops containing short helical segments on top. They are required for the formation of a deep cleft harbouring the catalytic Zn2+ site in Leukotriene A4 hydrolase.


Pssm-ID: 462686  Cd Length: 112  Bit Score: 33.23  E-value: 8.46e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034608939  18 VELLERLQRSGELPPQKLQALQRV----------LQSRFCS-AIREGWRSwRLPDAAA 64
Cdd:pfam09127   7 VVFLERLLEFSPLSPEQLKALDEVyklsesknaeIRFRWLRlALKAKYEP-AYPEVAE 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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