NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1046878706|ref|XP_017447051|]
View 

carbohydrate sulfotransferase 1 isoform X1 [Rattus norvegicus]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
200-384 1.54e-28

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 112.44  E-value: 1.54e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 200 RSHVAIKTVRVPEVNDLRALV----------EDPRLNLKVIQLVRDPRGILASRSETFRDTYRLwrLWYGTGrKPYNLDV 269
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTP-FEFVEDF 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 270 TQLTTVCEDFSSSVSTGLMRpsWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIP-----LDSHVARWIQNNTRGDPTLGK 344
Cdd:pfam00685 133 LNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPlteeeLDKIVKHLSFENMKGNPCLNY 210

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1046878706 345 HKY---GTVRNSAATAEKWRFRLSYDIVAFAQNACQHVLAQLG 384
Cdd:pfam00685 211 SKLpkeVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
200-384 1.54e-28

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 112.44  E-value: 1.54e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 200 RSHVAIKTVRVPEVNDLRALV----------EDPRLNLKVIQLVRDPRGILASRSETFRDTYRLwrLWYGTGrKPYNLDV 269
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTP-FEFVEDF 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 270 TQLTTVCEDFSSSVSTGLMRpsWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIP-----LDSHVARWIQNNTRGDPTLGK 344
Cdd:pfam00685 133 LNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPlteeeLDKIVKHLSFENMKGNPCLNY 210

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1046878706 345 HKY---GTVRNSAATAEKWRFRLSYDIVAFAQNACQHVLAQLG 384
Cdd:pfam00685 211 SKLpkeVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
200-384 1.54e-28

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 112.44  E-value: 1.54e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 200 RSHVAIKTVRVPEVNDLRALV----------EDPRLNLKVIQLVRDPRGILASRSETFRDTYRLwrLWYGTGrKPYNLDV 269
Cdd:pfam00685  56 YFDVAEGPVRLNALPSPRIIKthlplhllpkSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLL--KAPGTP-FEFVEDF 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 270 TQLTTVCEDFSSSVSTGLMRpsWLKGKYMLVRYEDLARNPMKKTEEIYEFLGIP-----LDSHVARWIQNNTRGDPTLGK 344
Cdd:pfam00685 133 LNGKVNCGSYFDHVKGWWKL--RPPGNILFLRYEDLKKDPRGEIKKIAEFLGIPlteeeLDKIVKHLSFENMKGNPCLNY 210

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1046878706 345 HKY---GTVRNSAATAEKWRFRLSYDIVAFAQNACQHVLAQLG 384
Cdd:pfam00685 211 SKLpkeVSPFFRKGLVGDWKNYFTPEQAEKFDEIYQEKMKGTG 253
Sulfotransfer_3 pfam13469
Sulfotransferase family;
226-325 6.14e-09

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 54.99  E-value: 6.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046878706 226 NLKVIQLVRDPRG-ILASRSETFRDTYRLWRlwygtgrkpyNLDVTQLTTVCEDFSSSVSTGL-MRPSWLKGKYMLVRYE 303
Cdd:pfam13469  81 DAKFIHLHRDPVDtVISSYCSLFGFTLSSYS----------TAFLRDIGLALARWSRAYERLMaARARVPPGRFLDVRYE 150

                          90       100
                  ....*....|....*....|..
gi 1046878706 304 DLARNPMKKTEEIYEFLGIPLD 325
Cdd:pfam13469 151 DLVADPEGTLRRILEFLGLPWD 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH