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Conserved domains on  [gi|1046852260|ref|XP_017453339|]
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chordin isoform X4 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
544-656 6.72e-25

A domain in the BMP inhibitor chordin and in microbial proteins;


:

Pssm-ID: 214804  Cd Length: 118  Bit Score: 100.11  E-value: 6.72e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  544 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 618
Cdd:smart00754   3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  619 GVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQVH 656
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
414-531 8.30e-24

A domain in the BMP inhibitor chordin and in microbial proteins;


:

Pssm-ID: 214804  Cd Length: 118  Bit Score: 97.03  E-value: 8.30e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  414 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVIGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQLGGHM 490
Cdd:smart00754   1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1046852260  491 AVGVCSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTA 531
Cdd:smart00754  78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
184-287 2.76e-11

A domain in the BMP inhibitor chordin and in microbial proteins;


:

Pssm-ID: 214804  Cd Length: 118  Bit Score: 61.21  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  184 TDFVALLTG------PRTQAVARARVSLL-RSSLRFSISYQRLDRPSRV-----RFTDPTG---NILFEHPAAptQDGLV 248
Cdd:smart00754   1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1046852260  249 CGVWRAVPRLSVRLLRAEQLRVALVTPTHPSEEVWGPLI 287
Cdd:smart00754  79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
295-408 3.85e-09

A domain in the BMP inhibitor chordin and in microbial proteins;


:

Pssm-ID: 214804  Cd Length: 118  Bit Score: 55.04  E-value: 3.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  295 ETFSAILTLE---DPLQRGVGGIALLTLSDTEDAL-HFLLLFRGLLGGLAHVPLKlQILHQGQLLRELQANASAQEPGFA 370
Cdd:smart00754   1 ETFSALLTGSqevPPVNTGAVGGAWFTLDDDGSLHyQVTLSGLSGPETAAHIHEG-EIGTNGPVVRIPLPNPTSREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  371 EVLPSLTDQEMDWLVLGELQMVLEKMGGPELRISGYIT 408
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 65-139 4.54e-08

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


:

Pssm-ID: 278520  Cd Length: 57  Bit Score: 50.12  E-value: 4.54e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046852260  65 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 139
Cdd:pfam00093   1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 715-772 2.54e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 42.41  E-value: 2.54e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 715 CFFEGQQRPHGARWAPNydpLCSLCTCQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 772
Cdd:pfam00093   1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
 
Name Accession Description Interval E-value
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
544-656 6.72e-25

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 100.11  E-value: 6.72e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  544 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 618
Cdd:smart00754   3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  619 GVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQVH 656
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
414-531 8.30e-24

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 97.03  E-value: 8.30e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  414 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVIGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQLGGHM 490
Cdd:smart00754   1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1046852260  491 AVGVCSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTA 531
Cdd:smart00754  78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 544-655 2.10e-14

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 70.20  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 544 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 615
Cdd:pfam07452   1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1046852260 616 EAQGVVKDLEPVLLRHLTQGTASLLIT--TKSNPRGELRGQV 655
Cdd:pfam07452  77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
184-287 2.76e-11

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 61.21  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  184 TDFVALLTG------PRTQAVARARVSLL-RSSLRFSISYQRLDRPSRV-----RFTDPTG---NILFEHPAAptQDGLV 248
Cdd:smart00754   1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1046852260  249 CGVWRAVPRLSVRLLRAEQLRVALVTPTHPSEEVWGPLI 287
Cdd:smart00754  79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 416-529 1.03e-10

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 59.80  E-value: 1.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 416 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVIGTG--------------SEVVAMTLETKPQRKNQRTVlc 479
Cdd:pfam07452   1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1046852260 480 hmaglqlgghmaVGVCSGLGARGAHMLLQN--ELFLNIGTKDFPDGELRGHV 529
Cdd:pfam07452  79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
295-408 3.85e-09

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 55.04  E-value: 3.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  295 ETFSAILTLE---DPLQRGVGGIALLTLSDTEDAL-HFLLLFRGLLGGLAHVPLKlQILHQGQLLRELQANASAQEPGFA 370
Cdd:smart00754   1 ETFSALLTGSqevPPVNTGAVGGAWFTLDDDGSLHyQVTLSGLSGPETAAHIHEG-EIGTNGPVVRIPLPNPTSREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  371 EVLPSLTDQEMDWLVLGELQMVLEKMGGPELRISGYIT 408
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 65-139 4.54e-08

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 50.12  E-value: 4.54e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046852260  65 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 139
Cdd:pfam00093   1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 715-772 2.54e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 42.41  E-value: 2.54e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 715 CFFEGQQRPHGARWAPNydpLCSLCTCQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 772
Cdd:pfam00093   1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
715-772 7.78e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 35.57  E-value: 7.78e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1046852260  715 CFFEGQQRPHGARWAPNYdplCSLCTCQRRTVI-CDPVV-CPPPSCPHPVQAL--DQCCPVC 772
Cdd:smart00214   1 CVHNGRVYNDGETWKPDP---CQICTCLDGTTVlCDPVEcPPPPDCPNPERVKppGECCPRC 59
 
Name Accession Description Interval E-value
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
544-656 6.72e-25

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 100.11  E-value: 6.72e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  544 LPVPLAGALVLPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQgtvTAHL-LGPPGMPGPQR--LLKGF--YGSEAQ 618
Cdd:smart00754   3 FSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPET---AAHIhEGEIGTNGPVVriPLPNPtsREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  619 GVVKDLEPVLLRHLTQGTASLLITTKSNPRGELRGQVH 656
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
414-531 8.30e-24

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 97.03  E-value: 8.30e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  414 DVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVIGTGSEVVAMTLETKPQRKN---QRTVLCHMaglQLGGHM 490
Cdd:smart00754   1 ETFSALLTGSQEVPPVNTGAVGGAWFTLDDDGSLHYQVTLSGLSGPETAAHIHEGEIGTNgpvVRIPLPNP---TSREGP 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1046852260  491 AVGVCSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTA 531
Cdd:smart00754  78 FAGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVAK 118
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 544-655 2.10e-14

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 70.20  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 544 LPVPLAGALVLPP-VRSQAAGHAWLSLDTHCH-LHYEVLLAGLggseQGTVTAHL-LGPPGMPGPQRL-----LKGFYGS 615
Cdd:pfam07452   1 FSALLTGAQEVPPpVTTGAGGTAVLTLDDTENtLHYTLTFSGL----SVPTAAHIhAGAAGFNGPVVVpleggPRKTTLL 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1046852260 616 EAQGVVKDLEPVLLRHLTQGTASLLIT--TKSNPRGELRGQV 655
Cdd:pfam07452  77 AVPEGLATLTAAQLAALLAQQGELYVNvhTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
184-287 2.76e-11

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 61.21  E-value: 2.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  184 TDFVALLTG------PRTQAVARARVSLL-RSSLRFSISYQRLDRPSRV-----RFTDPTG---NILFEHPAAptQDGLV 248
Cdd:smart00754   1 ETFSALLTGsqevppVNTGAVGGAWFTLDdDGSLHYQVTLSGLSGPETAahiheGEIGTNGpvvRIPLPNPTS--REGPF 78

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1046852260  249 CGVWRAVPRLSVRLLRAEQLRVALVTPTHPSEEVWGPLI 287
Cdd:smart00754  79 AGSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
CHRD pfam07452
CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in ...
 416-529 1.03e-10

CHRD domain; CHRD (after SWISS-PROT abbreviation for chordin) is a novel domain identified in chordin, an inhibitor of bone morphogenetic proteins. This family includes bacterial homologs. It is anticipated to have an immunoglobulin-like beta-barrel structure based on limited similarity to superoxide dismutases but, as yet, no clear functional prediction can be made. Its most conserved feature is a GE[I/L]RCG[V/I/L] motif towards its C-terminal end Most bacterial proteins in this family have only one CHRD domain, whereas it is found repeated in many eukaryotic proteins such as human chordin and Drosophila SOG..


Pssm-ID: 462167  Cd Length: 118  Bit Score: 59.80  E-value: 1.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 416 LQSVLCGADALIP-VQTGAAGSASFIL-LGNGSLIYQVQVIGTG--------------SEVVAMTLETKPQRKNQRTVlc 479
Cdd:pfam07452   1 FSALLTGAQEVPPpVTTGAGGTAVLTLdDTENTLHYTLTFSGLSvptaahihagaagfNGPVVVPLEGGPRKTTLLAV-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1046852260 480 hmaglqlgghmaVGVCSGLGARGAHMLLQN--ELFLNIGTKDFPDGELRGHV 529
Cdd:pfam07452  79 ------------PEGLATLTAAQLAALLAQqgELYVNVHTEGNPGGEIRGQI 118
CHRD smart00754
A domain in the BMP inhibitor chordin and in microbial proteins;
295-408 3.85e-09

A domain in the BMP inhibitor chordin and in microbial proteins;


Pssm-ID: 214804  Cd Length: 118  Bit Score: 55.04  E-value: 3.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  295 ETFSAILTLE---DPLQRGVGGIALLTLSDTEDAL-HFLLLFRGLLGGLAHVPLKlQILHQGQLLRELQANASAQEPGFA 370
Cdd:smart00754   1 ETFSALLTGSqevPPVNTGAVGGAWFTLDDDGSLHyQVTLSGLSGPETAAHIHEG-EIGTNGPVVRIPLPNPTSREGPFA 79

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1046852260  371 EVLPSLTDQEMDWLVLGELQMVLEKMGGPELRISGYIT 408
Cdd:smart00754  80 GSVKTLTDEELRQLLAGNLYVNVHTKANPGGEIRGQVA 117
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 65-139 4.54e-08

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 50.12  E-value: 4.54e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1046852260  65 CSFGGKVYALDETWHPDLgepfgvmrCVLCACEapqwarrgrgPGRVSCKNIKpqCPTLACRQPR--QLPGHCCQTC 139
Cdd:pfam00093   1 CVQNGVVYENGETWKPDL--------CTICTCD----------DGKVLCDKII--CPPLDCPNPRleIPPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 715-772 2.54e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 42.41  E-value: 2.54e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260 715 CFFEGQQRPHGARWAPNydpLCSLCTCQRRTVICDPVVCPPPSCPHP--VQALDQCCPVC 772
Cdd:pfam00093   1 CVQNGVVYENGETWKPD---LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 66-139 5.50e-04

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 43.15  E-value: 5.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046852260  66 SFGGKVYALDETWHPDLGEPFGVM----------------RCVLCAC---EAPQWArrgrgpgrvsCKNIKPQCPTLACR 126
Cdd:pfam14828 153 SLLGQTFTSDEDFAEFLSSRLGQLqfhgagalrvgpeacsDPSGCGCgndENLERI----------CANVLQRCPPPHCL 222

                          90
                  ....*....|...
gi 1046852260 127 QPRQLPGHCCQTC 139
Cdd:pfam14828 223 SPLRPEGHCCDVC 235
VWC smart00214
von Willebrand factor (vWF) type C domain;
715-772 7.78e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 35.57  E-value: 7.78e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1046852260  715 CFFEGQQRPHGARWAPNYdplCSLCTCQRRTVI-CDPVV-CPPPSCPHPVQAL--DQCCPVC 772
Cdd:smart00214   1 CVHNGRVYNDGETWKPDP---CQICTCLDGTTVlCDPVEcPPPPDCPNPERVKppGECCPRC 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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