|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
31-402 |
2.86e-156 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 448.41 E-value: 2.86e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 31 PNELLQEYNWELADQPQTLEEILLNCRTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLL 109
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 110 EYVTLRKMREMVGWP----GGCGDGIFSPGGAISNMYAMLIARFKMFPEVKEKGMATIP-----RLVAFTSEHSHFSVKK 180
Cdd:pfam00282 81 ENVVMNWLGEMLGLPaeflGQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKPADSsgilaKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 181 GAAALGIGtdsVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAW 260
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 261 GGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFqqdkHYDLSYDTGDKALQCG 340
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLG----HTDSAYDTGHKQIPLS 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1111000928 341 RHVDVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVFdgKPQHTNVCFWYI 402
Cdd:pfam00282 314 RRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICA--EVGLGLVCFRLK 373
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
71-474 |
5.56e-146 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 420.84 E-value: 5.56e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 71 YFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVGWPGGCGDGIFSPGGAISNMYAMLIARFK 150
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 151 MFPEVKEKGMATIPRLVAFTSEHSHFSVKKGAAALGIgtdSVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAG 230
Cdd:cd06450 81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 231 TTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVReeglmqs 310
Cdd:cd06450 158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 311 cnqmhasylfqqdkhydlsydtgdkalqcgrhvdVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdG 390
Cdd:cd06450 231 ----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELL--G 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 391 KPQHTNVCFWYIPPslrsmedneermSRLMKVAPVIKARMMEYGTTMVSYQPLGDKvNFFRMVISNPAATHQDIDFLIGE 470
Cdd:cd06450 275 EPNLSLVCFRLKPS------------VKLDELNYDLSDRLNERGGWHVPATTLGGP-NVLRFVVTNPLTTRDDADALLED 341
|
....
gi 1111000928 471 IERL 474
Cdd:cd06450 342 IERA 345
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
4-477 |
9.68e-145 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 422.32 E-value: 9.68e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 4 LQDVVDILLQYVvKSFDRSTKVIDfhyPNELLQEYNWELADQPQTLEEIL--LNcRTTLKYAIKTGHPRYFNQLSTGLDM 81
Cdd:COG0076 6 LHQALDLAADYL-AGLDRPVFGPS---PEELRAALDEPLPEEGLPPEEALaeLE-DLVLPGSVDWNHPRFLAFVTGGTTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 82 VGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVGWPGGCgDGIFSPGGAISNMYAMLIARFKMFPE-VKEKGM 160
Cdd:COG0076 81 AALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGA-GGVFTSGGTEANLLALLAARDRALARrVRAEGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 161 ATIPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPL 240
Cdd:COG0076 160 PGAPRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 241 IAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLF 320
Cdd:COG0076 240 AEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 321 QQDkhyDLSYDTGDKALQCGRHVDVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdGKPQHTNVCFW 400
Cdd:COG0076 320 PAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELL--APPELNIVCFR 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1111000928 401 YIPPSLRSM-EDNEErmsrlmkvapvIKARMMEYGTTMVSYQPLGDKVNfFRMVISNPAATHQDIDFLIGEIERLGQD 477
Cdd:COG0076 395 YKPAGLDEEdALNYA-----------LRDRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
|
|
| PLN02590 |
PLN02590 |
probable tyrosine decarboxylase |
44-464 |
7.36e-42 |
|
probable tyrosine decarboxylase
Pssm-ID: 178200 [Multi-domain] Cd Length: 539 Bit Score: 156.41 E-value: 7.36e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 44 DQPQTLEEILLNCRTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVG 122
Cdd:PLN02590 105 ERPESLKELLDDVSKKIMPGITHWQsPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 123 WPG-----GCGDGIFSPGGAISNMYAMLIARFKMFPEVkekGMATIPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIRC 197
Cdd:PLN02590 185 LPDhflstGNGGGVIQGTGCEAVLVVVLAARDRILKKV---GKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKT 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 198 DERGK--MIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLN 275
Cdd:PLN02590 262 DSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFID 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 276 GIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAK 355
Cdd:PLN02590 342 GIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLY 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 356 GSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdGKPQHTNVCFWYIPPSLRSMEDNEERMSRLMKVAPVikarmmeyGT 435
Cdd:PLN02590 422 GSENLRNFIRDHVNLAKHFEDYVAQDPSFEVV--TTRYFSLVCFRLAPVDGDEDQCNERNRELLAAVNST--------GK 491
|
410 420
....*....|....*....|....*....
gi 1111000928 436 TMVSYQPLGDKVnFFRMVISNPAATHQDI 464
Cdd:PLN02590 492 IFISHTALSGKF-VLRFAVGAPLTEEKHV 519
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Pyridoxal_deC |
pfam00282 |
Pyridoxal-dependent decarboxylase conserved domain; |
31-402 |
2.86e-156 |
|
Pyridoxal-dependent decarboxylase conserved domain;
Pssm-ID: 395219 Cd Length: 373 Bit Score: 448.41 E-value: 2.86e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 31 PNELLQEYNWELADQPQTLEEILLNCRTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLL 109
Cdd:pfam00282 1 PGYLKPLLPLAAPIIPEPELQIDGDIRRNLMPGVTTWHsPHFHAYMPTGNSYPSLLGDMLTDAINCNGFTWESSPACTEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 110 EYVTLRKMREMVGWP----GGCGDGIFSPGGAISNMYAMLIARFKMFPEVKEKGMATIP-----RLVAFTSEHSHFSVKK 180
Cdd:pfam00282 81 ENVVMNWLGEMLGLPaeflGQEGGGVLQPGSSESNLLALLAARTKWIKRMKAAGKPADSsgilaKLVAYTSDQAHSSIEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 181 GAAALGIGtdsVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAW 260
Cdd:pfam00282 161 AALYGGVK---LREIPSDDNGKMRGMDLEKAIEEDKENGLIPFFVVATLGTTGSGAFDDLQELGDICAKHNLWLHVDAAY 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 261 GGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFqqdkHYDLSYDTGDKALQCG 340
Cdd:pfam00282 238 GGSAFICPEFRHWLFGIERADSITFNPHKWMLVLLDCSAVWVKDKEALQQAFQFNPLYLG----HTDSAYDTGHKQIPLS 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1111000928 341 RHVDVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVFdgKPQHTNVCFWYI 402
Cdd:pfam00282 314 RRFRILKLWFVIRSLGVEGLQNQIRRHVELAQYLEALIRKDGRFEICA--EVGLGLVCFRLK 373
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
71-474 |
5.56e-146 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 420.84 E-value: 5.56e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 71 YFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVGWPGGCGDGIFSPGGAISNMYAMLIARFK 150
Cdd:cd06450 1 FLAGFVTTMDPPALLLEMLTSAKNAIDFTWDESPAATEMEAEVVNWLAKLFGLPSEDADGVFTSGGSESNLLALLAARDR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 151 MFPEVKEKGMATIPRLVAFTSEHSHFSVKKGAAALGIgtdSVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAG 230
Cdd:cd06450 81 ARKRLKAGGGRGIDKLVIVCSDQAHVSVEKAAAYLDV---KVRLVPVDEDGRMDPEALEAAIDEDKAEGLNPIMVVATAG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 231 TTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVReeglmqs 310
Cdd:cd06450 158 TTDTGAIDPLEEIADLAEKYDLWLHVDAAYGGFLLPFPEPRHLDFGIERVDSISVDPHKYGLVPLGCSAVLVR------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 311 cnqmhasylfqqdkhydlsydtgdkalqcgrhvdVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdG 390
Cdd:cd06450 231 ----------------------------------ALKLWATLRRFGRDGYGEHIDRIVDLAKYLAELIRADPGFELL--G 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 391 KPQHTNVCFWYIPPslrsmedneermSRLMKVAPVIKARMMEYGTTMVSYQPLGDKvNFFRMVISNPAATHQDIDFLIGE 470
Cdd:cd06450 275 EPNLSLVCFRLKPS------------VKLDELNYDLSDRLNERGGWHVPATTLGGP-NVLRFVVTNPLTTRDDADALLED 341
|
....
gi 1111000928 471 IERL 474
Cdd:cd06450 342 IERA 345
|
|
| GadA |
COG0076 |
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport ... |
4-477 |
9.68e-145 |
|
Glutamate or tyrosine decarboxylase or a related PLP-dependent protein [Amino acid transport and metabolism]; Glutamate or tyrosine decarboxylase or a related PLP-dependent protein is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 439846 [Multi-domain] Cd Length: 460 Bit Score: 422.32 E-value: 9.68e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 4 LQDVVDILLQYVvKSFDRSTKVIDfhyPNELLQEYNWELADQPQTLEEIL--LNcRTTLKYAIKTGHPRYFNQLSTGLDM 81
Cdd:COG0076 6 LHQALDLAADYL-AGLDRPVFGPS---PEELRAALDEPLPEEGLPPEEALaeLE-DLVLPGSVDWNHPRFLAFVTGGTTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 82 VGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVGWPGGCgDGIFSPGGAISNMYAMLIARFKMFPE-VKEKGM 160
Cdd:COG0076 81 AALAADLLASALNQNMGDWDTSPAATELEREVVRWLADLLGLPEGA-GGVFTSGGTEANLLALLAARDRALARrVRAEGL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 161 ATIPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIRCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPL 240
Cdd:COG0076 160 PGAPRPRIVVSEEAHSSVDKAARLLGLGRDALRKVPVDEDGRMDPDALEAAIDEDRAAGLNPIAVVATAGTTNTGAIDPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 241 IAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLF 320
Cdd:COG0076 240 AEIADIAREHGLWLHVDAAYGGFALPSPELRHLLDGIERADSITVDPHKWLYVPYGCGAVLVRDPELLREAFSFHASYLG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 321 QQDkhyDLSYDTGDKALQCGRHVDVFKLWLMWRAKGSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdGKPQHTNVCFW 400
Cdd:COG0076 320 PAD---DGVPNLGDYTLELSRRFRALKLWATLRALGREGYRELIERCIDLARYLAEGIAALPGFELL--APPELNIVCFR 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1111000928 401 YIPPSLRSM-EDNEErmsrlmkvapvIKARMMEYGTTMVSYQPLGDKVNfFRMVISNPAATHQDIDFLIGEIERLGQD 477
Cdd:COG0076 395 YKPAGLDEEdALNYA-----------LRDRLRARGRAFLSPTKLDGRVV-LRLVVLNPRTTEDDVDALLDDLREAAAE 460
|
|
| PLN02590 |
PLN02590 |
probable tyrosine decarboxylase |
44-464 |
7.36e-42 |
|
probable tyrosine decarboxylase
Pssm-ID: 178200 [Multi-domain] Cd Length: 539 Bit Score: 156.41 E-value: 7.36e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 44 DQPQTLEEILLNCRTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVG 122
Cdd:PLN02590 105 ERPESLKELLDDVSKKIMPGITHWQsPSYFAYYASSTSVAGFLGEMLNAGLSVVGFTWLTSPAATELEIIVLDWLAKLLQ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 123 WPG-----GCGDGIFSPGGAISNMYAMLIARFKMFPEVkekGMATIPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIRC 197
Cdd:PLN02590 185 LPDhflstGNGGGVIQGTGCEAVLVVVLAARDRILKKV---GKTLLPQLVVYGSDQTHSSFRKACLIGGIHEENIRLLKT 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 198 DERGK--MIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLN 275
Cdd:PLN02590 262 DSSTNygMPPESLEEAISHDLAKGFIPFFICATVGTTSSAAVDPLVPLGNIAKKYGIWLHVDAAYAGNACICPEYRKFID 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 276 GIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAK 355
Cdd:PLN02590 342 GIENADSFNMNAHKWLFANQTCSPLWVKDRYSLIDALKTNPEYLEFKVSKKDTVVNYKDWQISLSRRFRSLKLWMVLRLY 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 356 GSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdGKPQHTNVCFWYIPPSLRSMEDNEERMSRLMKVAPVikarmmeyGT 435
Cdd:PLN02590 422 GSENLRNFIRDHVNLAKHFEDYVAQDPSFEVV--TTRYFSLVCFRLAPVDGDEDQCNERNRELLAAVNST--------GK 491
|
410 420
....*....|....*....|....*....
gi 1111000928 436 TMVSYQPLGDKVnFFRMVISNPAATHQDI 464
Cdd:PLN02590 492 IFISHTALSGKF-VLRFAVGAPLTEEKHV 519
|
|
| PLN02880 |
PLN02880 |
tyrosine decarboxylase |
44-418 |
2.30e-34 |
|
tyrosine decarboxylase
Pssm-ID: 215475 [Multi-domain] Cd Length: 490 Bit Score: 134.65 E-value: 2.30e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 44 DQPQTLEEILLNCRTTLKYAIKTGH-PRYFNQLSTGLDMVGLAADWLTSAANTNMFTYEIAPVFVLLEYVTLRKMREMVG 122
Cdd:PLN02880 57 NQPETLDQVLDDVQAKILPGVTHWQsPNYFAYYPSNSSVAGFLGEMLSAGLNIVGFSWITSPAATELEMIVLDWLAKLLN 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 123 WP-----GGCGDGIFSPGGAISNMYAMLIARFKMfpeVKEKGMATIPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIR- 196
Cdd:PLN02880 137 LPeqflsTGNGGGVIQGTASEAVLVVLLAARDRV---LRKVGKNALEKLVVYASDQTHSALQKACQIAGIHPENCRLLKt 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 197 -CDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMSRKHKWKLN 275
Cdd:PLN02880 214 dSSTNYALAPELLSEAISTDLSSGLIPFFLCATVGTTSSTAVDPLLELGKIAKSNGMWFHVDAAYAGSACICPEYRHYID 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 276 GIERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAK 355
Cdd:PLN02880 294 GVEEADSFNMNAHKWFLTNFDCSLLWVKDRNALIQSLSTNPEFLKNKASQANSVVDYKDWQIPLGRRFRSLKLWMVLRLY 373
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1111000928 356 GSTGFEAQIDKCLELAEYLYNKIKNREGYEMVfdGKPQHTNVCFWYIPPSlrSMEDNEERMSR 418
Cdd:PLN02880 374 GVENLQSYIRNHIKLAKEFEQLVAQDSRFEVV--TPRIFSLVCFRLVPPK--NNEDNGNKLNH 432
|
|
| PRK02769 |
PRK02769 |
histidine decarboxylase; Provisional |
130-382 |
9.63e-23 |
|
histidine decarboxylase; Provisional
Pssm-ID: 235068 [Multi-domain] Cd Length: 380 Bit Score: 99.73 E-value: 9.63e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 130 GIFSPGGAISNMYAMLIARfKMFPEVkekgmatiprlVAFTSEHSHFSVKKGAAALGIGTDsviLIRCDERGKMIPSDLE 209
Cdd:PRK02769 87 GYITNGGTEGNLYGCYLAR-ELFPDG-----------TLYYSKDTHYSVSKIARLLRIKSR---VITSLPNGEIDYDDLI 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 210 RRILEAKQKgfvPFLVSATAGTTVYGAFDPLIAIADICKKYKI---WMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWN 286
Cdd:PRK02769 152 SKIKENKNQ---PPIIFANIGTTMTGAIDNIKEIQEILKKIGIddyYIHADAALSGMILPFVNNPPPFSFADGIDSIAIS 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 287 PHKMMGVPLQCSALLVREEGLMQscNQMHASYLfqqdkhydlsyDTGDKALQCGR--HVDVFkLWLMWRAKGSTGFEAQI 364
Cdd:PRK02769 229 GHKFIGSPMPCGIVLAKKKYVER--ISVDVDYI-----------GSRDQTISGSRngHTALL-LWAAIRSLGSKGLRQRV 294
|
250
....*....|....*...
gi 1111000928 365 DKCLELAEYLYNKIKNRE 382
Cdd:PRK02769 295 QHCLDMAQYAVDRLQANG 312
|
|
| PLN03032 |
PLN03032 |
serine decarboxylase; Provisional |
130-379 |
4.84e-14 |
|
serine decarboxylase; Provisional
Pssm-ID: 166673 [Multi-domain] Cd Length: 374 Bit Score: 73.32 E-value: 4.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 130 GIFSPGGAISNMYAMLIARFKMfpevkekgmatiPRLVAFTSEHSHFSVKKGAAALGIGTDSVILIrcdERGKMIPSDLE 209
Cdd:PLN03032 88 GYITTCGTEGNLHGILVGREVF------------PDGILYASRESHYSVFKAARMYRMEAVKVPTL---PSGEIDYDDLE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 210 RRILEAKQKgfvPFLVSATAGTTVYGAFDPLIAIADICKKYKI-----WMHVDGAWGGGLLMSRKHKWKLNGIERANSVT 284
Cdd:PLN03032 153 RALAKNRDK---PAILNVNIGTTVKGAVDDLDRILRILKELGYtedrfYIHCDGALFGLMMPFVSRAPEVTFRKPIGSVS 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 285 WNPHKMMGVPLQCSALLVREEGLMQscnqmhasylFQQDKHYDLSYDTGDKALQCGrHVDVFkLWLMWRAKGSTGFEAQI 364
Cdd:PLN03032 230 VSGHKFLGCPMPCGVALTRKKHVKA----------LSQNVEYLNSRDATIMGSRNG-HAPLY-LWYTLRRKGYRGIKRDV 297
|
250
....*....|....*
gi 1111000928 365 DKCLELAEYLYNKIK 379
Cdd:PLN03032 298 QHCMRNAHYLKDRLT 312
|
|
| PLN02263 |
PLN02263 |
serine decarboxylase |
136-380 |
5.29e-13 |
|
serine decarboxylase
Pssm-ID: 177904 [Multi-domain] Cd Length: 470 Bit Score: 70.62 E-value: 5.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 136 GAISNMYAMLIARfKMFPEVkekgmatiprlVAFTSEHSHFSVKKGAAALGIGtdsVILIRCDERGKMIPSDLERRILEA 215
Cdd:PLN02263 161 GTEGNLHGILVGR-EVFPDG-----------ILYASRESHYSVFKAARMYRME---CVKVDTLVSGEIDCADFKAKLLAN 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 216 KQKgfvPFLVSATAGTTVYGAFDPLIAIADICKKY-----KIWMHVDGAWGGGLLMSRKHKWKLNGIERANSVTWNPHKM 290
Cdd:PLN02263 226 KDK---PAIINVNIGTTVKGAVDDLDLVIKTLEECgfsqdRFYIHCDGALFGLMMPFVKRAPKVTFKKPIGSVSVSGHKF 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 291 MGVPLQCSALLVREEglmqscnqmHASYLfQQDKHYDLSYDTGDKALQCGrHVDVFkLWLMWRAKGSTGFEAQIDKCLEL 370
Cdd:PLN02263 303 VGCPMPCGVQITRME---------HINVL-SSNVEYLASRDATIMGSRNG-HAPIF-LWYTLNRKGYRGFQKEVQKCLRN 370
|
250
....*....|
gi 1111000928 371 AEYLYNKIKN 380
Cdd:PLN02263 371 AHYLKDRLRE 380
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
124-303 |
1.26e-12 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 65.87 E-value: 1.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 124 PGGCGDGIFSPGGAISNMYAMLIARfkmfpevkekgmatIPRLVAFTSEHSHFSVKKGAAALgIGTDSVIlIRCDERGKM 203
Cdd:cd01494 14 QPGNDKAVFVPSGTGANEAALLALL--------------GPGDEVIVDANGHGSRYWVAAEL-AGAKPVP-VPVDDAGYG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 204 IpsdLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAWGGGllmSRKHKWKLNGIERANSV 283
Cdd:cd01494 78 G---LDVAILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGG---ASPAPGVLIPEGGADVV 151
|
170 180
....*....|....*....|
gi 1111000928 284 TWNPHKMMGVPlQCSALLVR 303
Cdd:cd01494 152 TFSLHKNLGGE-GGGVVIVK 170
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
173-259 |
5.78e-05 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 44.90 E-value: 5.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 173 HSHFSVKKGAAALGIGTdsVILIRCDERGKMIPSDLERRILEAKQKGFVPF-LVSAT-----AGTTVYgAFDPLIAIADI 246
Cdd:pfam01212 81 HIHFDETGGHAELGGVQ--PRPLDGDEAGNMDLEDLEAAIREVGADIFPPTgLISLEnthnsAGGQVV-SLENLREIAAL 157
|
90
....*....|...
gi 1111000928 247 CKKYKIWMHVDGA 259
Cdd:pfam01212 158 AREHGIPVHLDGA 170
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
224-399 |
2.36e-04 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 43.39 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 224 LVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGAWGgglLMSRKHKWKLNGIERANSVTwnpHKMMGvPLQCSALLVR 303
Cdd:pfam00266 142 LVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVDAAQA---IGHRPIDVQKLGVDFLAFSG---HKLYG-PTGIGVLYGR 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 304 EEGLmqscNQMH-----ASYLFQQDKHYDLSYDTGDK----------ALQCGRHVDvfklWLMwrakgSTGFEAQIDKCL 368
Cdd:pfam00266 215 RDLL----EKMPpllggGGMIETVSLQESTFADAPWKfeagtpniagIIGLGAALE----YLS-----EIGLEAIEKHEH 281
|
170 180 190
....*....|....*....|....*....|.
gi 1111000928 369 ELAEYLYNKIKNREGYEmVFDGKPQHTNVCF 399
Cdd:pfam00266 282 ELAQYLYERLLSLPGIR-LYGPERRASIISF 311
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
232-317 |
1.85e-03 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 40.31 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1111000928 232 TVYGAFDPLIAIADICKKYKIWMHVDGAWGGGLLMS---RKHKWKLNGIERANSVtwnpHKMMGVPLQCSALLVREEGL- 307
Cdd:cd00615 164 TYYGICYNLRKIVEEAHHRGLPVLVDEAHGAHFRFHpilPSSAAMAGADIVVQST----HKTLPALTQGSMIHVKGDLVn 239
|
90
....*....|...
gi 1111000928 308 ---MQSCNQMHAS 317
Cdd:cd00615 240 pdrVNEALNLHQS 252
|
|
| TA_like |
cd06502 |
Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP) ... |
199-259 |
2.58e-03 |
|
Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a secondary glycine biosynthetic pathway.
Pssm-ID: 99748 [Multi-domain] Cd Length: 338 Bit Score: 40.01 E-value: 2.58e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1111000928 199 ERGKMIPSDLERRILEAKQKGFV-PFLVS---ATAGTTVYgAFDPLIAIADICKKYKIWMHVDGA 259
Cdd:cd06502 104 ENGKLTPEDLEAAIRPRDDIHFPpPSLVSlenTTEGGTVY-PLDELKAISALAKENGLPLHLDGA 167
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
192-259 |
7.18e-03 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 38.58 E-value: 7.18e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1111000928 192 VILIRCDERGKMIPSDLERrILEAKQKgfvpfLVSATAGTTVYGAFDPLIAIADICKKYKIWMHVDGA 259
Cdd:COG0520 131 VRVIPLDEDGELDLEALEA-LLTPRTK-----LVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVDGA 192
|
|
| |
