fungal transcription factor regulatory middle homology region; This domain is present in the ...
249-729
1.82e-35
fungal transcription factor regulatory middle homology region; This domain is present in the large family of fungal zinc cluster transcription factors that contain an N-terminal GAL4-like C6 zinc binuclear cluster DNA-binding domain. Examples of members of this large fungal group are the following Saccharomyces cerevisiae transcription factors, GAL4, STB5, DAL81, CAT8, RDR1, HAL9, PUT3, PPR1, ASG1, RSF2, PIP2, as well as the C-terminal domain of the Cep3, a subunit of the yeast centromere-binding factor 3. It has been suggested that this region plays a regulatory role.
:
Pssm-ID: 213391 Cd Length: 410 Bit Score: 139.89 E-value: 1.82e-35
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like ...
23-56
6.11e-09
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like GAL4. Domain consists of two helices organized around a Zn(2)Cys(6 )motif; Binds to sequences containing 2 DNA half sites comprised of 3-5 C/G combinations
:
Pssm-ID: 238023 [Multi-domain] Cd Length: 36 Bit Score: 52.28 E-value: 6.11e-09
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx ...
688-791
6.87e-04
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives of this protein. The family includes the MRS2 protein from yeast that is thought to be an RNA splicing protein. However its membership of this family suggests that its effect on splicing is due to altered magnesium levels in the cell.
The actual alignment was detected with superfamily member pfam01544:
Pssm-ID: 460246 [Multi-domain] Cd Length: 292 Bit Score: 42.69 E-value: 6.87e-04
fungal transcription factor regulatory middle homology region; This domain is present in the ...
249-729
1.82e-35
fungal transcription factor regulatory middle homology region; This domain is present in the large family of fungal zinc cluster transcription factors that contain an N-terminal GAL4-like C6 zinc binuclear cluster DNA-binding domain. Examples of members of this large fungal group are the following Saccharomyces cerevisiae transcription factors, GAL4, STB5, DAL81, CAT8, RDR1, HAL9, PUT3, PPR1, ASG1, RSF2, PIP2, as well as the C-terminal domain of the Cep3, a subunit of the yeast centromere-binding factor 3. It has been suggested that this region plays a regulatory role.
Pssm-ID: 213391 Cd Length: 410 Bit Score: 139.89 E-value: 1.82e-35
Fungal specific transcription factor domain; This domain is found in a number of fungal ...
409-497
2.82e-18
Fungal specific transcription factor domain; This domain is found in a number of fungal transcription factors including transcriptional activator xlnR, yeast regulatory protein GAL4, and other transcription proteins regulating a variety of cellular and metabolic processes.
Pssm-ID: 214903 [Multi-domain] Cd Length: 93 Bit Score: 80.58 E-value: 2.82e-18
Fungal specific transcription factor domain; This domain is found in a number of fungal ...
411-564
2.46e-10
Fungal specific transcription factor domain; This domain is found in a number of fungal transcription factors including transcriptional activator xlnR, yeast regulatory protein GAL4, and nicotinate catabolism cluster-specific transcription factor HxnR.
Pssm-ID: 397964 Cd Length: 262 Bit Score: 62.12 E-value: 2.46e-10
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like ...
23-56
6.11e-09
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like GAL4. Domain consists of two helices organized around a Zn(2)Cys(6 )motif; Binds to sequences containing 2 DNA half sites comprised of 3-5 C/G combinations
Pssm-ID: 238023 [Multi-domain] Cd Length: 36 Bit Score: 52.28 E-value: 6.11e-09
GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain; Gal4 is a positive ...
22-56
8.32e-09
GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain; Gal4 is a positive regulator for the gene expression of the galactose- induced genes of S. cerevisiae. Is present only in fungi.
Pssm-ID: 214501 [Multi-domain] Cd Length: 43 Bit Score: 51.98 E-value: 8.32e-09
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx ...
688-791
6.87e-04
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives of this protein. The family includes the MRS2 protein from yeast that is thought to be an RNA splicing protein. However its membership of this family suggests that its effect on splicing is due to altered magnesium levels in the cell.
Pssm-ID: 460246 [Multi-domain] Cd Length: 292 Bit Score: 42.69 E-value: 6.87e-04
fungal transcription factor regulatory middle homology region; This domain is present in the ...
249-729
1.82e-35
fungal transcription factor regulatory middle homology region; This domain is present in the large family of fungal zinc cluster transcription factors that contain an N-terminal GAL4-like C6 zinc binuclear cluster DNA-binding domain. Examples of members of this large fungal group are the following Saccharomyces cerevisiae transcription factors, GAL4, STB5, DAL81, CAT8, RDR1, HAL9, PUT3, PPR1, ASG1, RSF2, PIP2, as well as the C-terminal domain of the Cep3, a subunit of the yeast centromere-binding factor 3. It has been suggested that this region plays a regulatory role.
Pssm-ID: 213391 Cd Length: 410 Bit Score: 139.89 E-value: 1.82e-35
Fungal specific transcription factor domain; This domain is found in a number of fungal ...
409-497
2.82e-18
Fungal specific transcription factor domain; This domain is found in a number of fungal transcription factors including transcriptional activator xlnR, yeast regulatory protein GAL4, and other transcription proteins regulating a variety of cellular and metabolic processes.
Pssm-ID: 214903 [Multi-domain] Cd Length: 93 Bit Score: 80.58 E-value: 2.82e-18
Fungal specific transcription factor domain; This domain is found in a number of fungal ...
411-564
2.46e-10
Fungal specific transcription factor domain; This domain is found in a number of fungal transcription factors including transcriptional activator xlnR, yeast regulatory protein GAL4, and nicotinate catabolism cluster-specific transcription factor HxnR.
Pssm-ID: 397964 Cd Length: 262 Bit Score: 62.12 E-value: 2.46e-10
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like ...
23-56
6.11e-09
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like GAL4. Domain consists of two helices organized around a Zn(2)Cys(6 )motif; Binds to sequences containing 2 DNA half sites comprised of 3-5 C/G combinations
Pssm-ID: 238023 [Multi-domain] Cd Length: 36 Bit Score: 52.28 E-value: 6.11e-09
GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain; Gal4 is a positive ...
22-56
8.32e-09
GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain; Gal4 is a positive regulator for the gene expression of the galactose- induced genes of S. cerevisiae. Is present only in fungi.
Pssm-ID: 214501 [Multi-domain] Cd Length: 43 Bit Score: 51.98 E-value: 8.32e-09
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx ...
688-791
6.87e-04
CorA-like Mg2+ transporter protein; The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli. CorA is virtually ubiquitous in the Bacteria and Archaea. There are also eukaryotic relatives of this protein. The family includes the MRS2 protein from yeast that is thought to be an RNA splicing protein. However its membership of this family suggests that its effect on splicing is due to altered magnesium levels in the cell.
Pssm-ID: 460246 [Multi-domain] Cd Length: 292 Bit Score: 42.69 E-value: 6.87e-04
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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