NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1370475509|ref|XP_024307378|]
View 

asc-type amino acid transporter 1 isoform X3 [Homo sapiens]

Protein Classification

amino acid permease( domain architecture ID 1000062)

amino acid permease facilitates the transport of amino acids, similar to solute carrier family 7 (SLC7) members

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
2A0308 super family cl30119
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 97-471 2.35e-161

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


The actual alignment was detected with superfamily member TIGR00911:

Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 466.92  E-value: 2.35e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  97 WSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 176
Cdd:TIGR00911 128 WIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIII 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 177 VGLLQIFQGHFEELRPSNAFAfWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFT 256
Cdd:TIGR00911 208 TGWVQLGKGGVESLNPKNAFE-GTETSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLT 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 257 NIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCT 336
Cdd:TIGR00911 287 NIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLT 366

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 337 PIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFI 416
Cdd:TIGR00911 367 PLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLY 446

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370475509 417 SEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 471
Cdd:TIGR00911 447 SPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQKVLEVVKPQK 501
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
2-84 9.76e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 38.68  E-value: 9.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509   2 RPPVGAVPAARAVSSRTDGPTGGRPDRR--GSAGSGDA---AGQR----HGRPHAAAERAREPQACALALPSPR-----D 67
Cdd:PRK07003  518 REDAPAAAAPPAPEARPPTPAAAAPAARagGAAAALDVlrnAGMRvssdRGARAAAAAKPAAAPAAAPKPAAPRvavqvP 597

                          90
                  ....*....|....*..
gi 1370475509  68 RPRRLGAGGAQEGDRAA 84
Cdd:PRK07003  598 TPRARAATGDAPPNGAA 614
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 97-471 2.35e-161

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 466.92  E-value: 2.35e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  97 WSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 176
Cdd:TIGR00911 128 WIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIII 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 177 VGLLQIFQGHFEELRPSNAFAfWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFT 256
Cdd:TIGR00911 208 TGWVQLGKGGVESLNPKNAFE-GTETSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLT 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 257 NIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCT 336
Cdd:TIGR00911 287 NIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLT 366

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 337 PIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFI 416
Cdd:TIGR00911 367 PLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLY 446

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370475509 417 SEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 471
Cdd:TIGR00911 447 SPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQKVLEVVKPQK 501
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
99-438 9.04e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.54  E-value: 9.04e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  99 AVLIMYPTSLAVISMTFSNYvLQPVFPncippTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVG 178
Cdd:COG0531    96 ALLLSYVLAVAAVAVAFGGY-LSSLFP-----AGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVVG 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 179 LLQIFQGHFEELRPSNafafwmtPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNI 258
Cdd:COG0531   170 LFAFDPANFTPFLPAG-------GGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSL 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 259 AYFTAMSPQELLSSNAVAVTFGEKLLG-YFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTP 337
Cdd:COG0531   243 ALTGVVPYDELAASGAPLADAAEAVFGpWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRFGTP 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 338 IPALLVCCGATAVIMLVG--DTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNL-LIPVAYLVFWAFLLVFS 414
Cdd:COG0531   323 VNAILLTGVIALLLLLLGaaSFTALASLASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLpLIPILGILLCLFLLYLL 402

                         330       340
                  ....*....|....*....|....
gi 1370475509 415 FISEPMvcgVGVIIILTGVPIFFL 438
Cdd:COG0531   403 GPGALL---IGLVLLAIGLLLYLL 423
AA_permease_2 pfam13520
Amino acid permease;
104-416 7.27e-26

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 109.71  E-value: 7.27e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 104 YPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQD-MFTGGKLLALSLIIGVGLLQI 182
Cdd:pfam13520  88 YVLGLASSASVAASYLLSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNiLGILKLLLPLILIIILGLVTA 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 183 FQGHFEElrPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMvdARKNLPRAIFISIPLVTFVYTFTNIAYFT 262
Cdd:pfam13520 168 DGGGFNL--LSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGVIIVGVLYILVNIAFFG 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 263 AMSPQELLSSN----AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHV-RHCTP 337
Cdd:pfam13520 244 VVPDDEIALSSglgqVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVnKFGSP 323

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 338 IPALL---VCCGATAVIMLVGDT--YTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVnllIPVAYL--VFWAFL 410
Cdd:pfam13520 324 IRAIIltaILSLILLLLFLLSPAayNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGR---WPVAIFgiLFSLFL 400


                  ....*.
gi 1370475509 411 LVFSFI 416
Cdd:pfam13520 401 IVALFF 406
frlA PRK11357
amino acid permease;
97-447 2.84e-13

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 71.81  E-value: 2.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  97 WSAVLIMYPTSLAVISMTFSNYV--LQPVFPncipptTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLI 174
Cdd:PRK11357   94 WASFWANDAPSLSIMALAIVSNLgfLTPIDP------LLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIV 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 175 IGVGLLQIFQGHFEELRPSNAFAfwmTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYT 254
Cdd:PRK11357  168 IGLGIFWFKAENFAAPTTTAIGA---TGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYT 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 255 FTNIAYFTAMSPQELLSSN---AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIH 331
Cdd:PRK11357  245 LLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVH 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 332 VRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI----NYLCYGVTILGLLLL--RWRRPALHRPIKVNLLIPVAYLV 405
Cdd:PRK11357  325 PKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVmcfkNTLTFGSIIWCRKRDdyKPLWRTPAFGLMTTLAIASSLIL 404

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1370475509 406 FWAfllvfSFISEPM---VCgvGVIIILTGVPIFFlgvFWRSKPK 447
Cdd:PRK11357  405 VAS-----TFVWAPIpglIC--AVIVIATGLPAYA---FWAKRSR 439
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2-84 9.76e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 38.68  E-value: 9.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509   2 RPPVGAVPAARAVSSRTDGPTGGRPDRR--GSAGSGDA---AGQR----HGRPHAAAERAREPQACALALPSPR-----D 67
Cdd:PRK07003  518 REDAPAAAAPPAPEARPPTPAAAAPAARagGAAAALDVlrnAGMRvssdRGARAAAAAKPAAAPAAAPKPAAPRvavqvP 597

                          90
                  ....*....|....*..
gi 1370475509  68 RPRRLGAGGAQEGDRAA 84
Cdd:PRK07003  598 TPRARAATGDAPPNGAA 614
 
Name Accession Description Interval E-value
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 97-471 2.35e-161

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 466.92  E-value: 2.35e-161
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  97 WSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIG 176
Cdd:TIGR00911 128 WIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAIRLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLLALLLIII 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 177 VGLLQIFQGHFEELRPSNAFAfWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFT 256
Cdd:TIGR00911 208 TGWVQLGKGGVESLNPKNAFE-GTETSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMPIVTFIYVLT 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 257 NIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCT 336
Cdd:TIGR00911 287 NIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMPALVGLSCFGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLT 366

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 337 PIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFI 416
Cdd:TIGR00911 367 PLPSLLIVCTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLLWLRYKRPEMNRPIKVPLFFPVFFLLSCLFLIILSLY 446

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370475509 417 SEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQD 471
Cdd:TIGR00911 447 SPPVGCGVGFIIMLTGVPVYFFGVWWQNKPKWFRYLIVSKTVLLQKVLEVVKPQK 501
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
99-438 9.04e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.54  E-value: 9.04e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  99 AVLIMYPTSLAVISMTFSNYvLQPVFPncippTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVG 178
Cdd:COG0531    96 ALLLSYVLAVAAVAVAFGGY-LSSLFP-----AGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVLLLFIVVG 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 179 LLQIFQGHFEELRPSNafafwmtPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNI 258
Cdd:COG0531   170 LFAFDPANFTPFLPAG-------GGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVSL 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 259 AYFTAMSPQELLSSNAVAVTFGEKLLG-YFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTP 337
Cdd:COG0531   243 ALTGVVPYDELAASGAPLADAAEAVFGpWGAILIALGALLSLLGALNASILGASRLLYAMARDGLLPKVFAKVHPRFGTP 322

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 338 IPALLVCCGATAVIMLVG--DTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNL-LIPVAYLVFWAFLLVFS 414
Cdd:COG0531   323 VNAILLTGVIALLLLLLGaaSFTALASLASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLpLIPILGILLCLFLLYLL 402

                         330       340
                  ....*....|....*....|....
gi 1370475509 415 FISEPMvcgVGVIIILTGVPIFFL 438
Cdd:COG0531   403 GPGALL---IGLVLLAIGLLLYLL 423
AA_permease_2 pfam13520
Amino acid permease;
104-416 7.27e-26

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 109.71  E-value: 7.27e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 104 YPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQD-MFTGGKLLALSLIIGVGLLQI 182
Cdd:pfam13520  88 YVLGLASSASVAASYLLSALGPDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNiLGILKLLLPLILIIILGLVTA 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 183 FQGHFEElrPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMvdARKNLPRAIFISIPLVTFVYTFTNIAYFT 262
Cdd:pfam13520 168 DGGGFNL--LSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEV--KKRNVPKAIFIGVIIVGVLYILVNIAFFG 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 263 AMSPQELLSSN----AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHV-RHCTP 337
Cdd:pfam13520 244 VVPDDEIALSSglgqVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVnKFGSP 323

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 338 IPALL---VCCGATAVIMLVGDT--YTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVnllIPVAYL--VFWAFL 410
Cdd:pfam13520 324 IRAIIltaILSLILLLLFLLSPAayNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGR---WPVAIFgiLFSLFL 400


                  ....*.
gi 1370475509 411 LVFSFI 416
Cdd:pfam13520 401 IVALFF 406
frlA PRK11357
amino acid permease;
97-447 2.84e-13

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 71.81  E-value: 2.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509  97 WSAVLIMYPTSLAVISMTFSNYV--LQPVFPncipptTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLI 174
Cdd:PRK11357   94 WASFWANDAPSLSIMALAIVSNLgfLTPIDP------LLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIV 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 175 IGVGLLQIFQGHFEELRPSNAFAfwmTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYT 254
Cdd:PRK11357  168 IGLGIFWFKAENFAAPTTTAIGA---TGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYT 244

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 255 FTNIAYFTAMSPQELLSSN---AVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIH 331
Cdd:PRK11357  245 LLALVISGLMPFDKLANSEtpiSDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFGHVH 324

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 332 VRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFI----NYLCYGVTILGLLLL--RWRRPALHRPIKVNLLIPVAYLV 405
Cdd:PRK11357  325 PKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVmcfkNTLTFGSIIWCRKRDdyKPLWRTPAFGLMTTLAIASSLIL 404

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1370475509 406 FWAfllvfSFISEPM---VCgvGVIIILTGVPIFFlgvFWRSKPK 447
Cdd:PRK11357  405 VAS-----TFVWAPIpglIC--AVIVIATGLPAYA---FWAKRSR 439
AA_permease pfam00324
Amino acid permease;
136-417 9.73e-12

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 66.96  E-value: 9.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 136 VLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRP-----SNAFAFWMTPSVGH-LAL 209
Cdd:pfam00324 115 VWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIILLSGGNPNDGAIfrylgDNGGKNNFPPGFGKgFIS 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 210 AFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVA------VTFGEKL 283
Cdd:pfam00324 195 VFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSAsaaspfVIFFKFL 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 284 -LGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAmIHVRHCTPIPALLVCCGATAVIMLVGDTYT--- 359
Cdd:pfam00324 275 gISGLAPLINAVILTAALSAANSSLYSGSRMLYSLARDGLAPKFLK-KVDKRGVPLRAILVSMVISLLALLLASLNPaiv 353

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370475509 360 ---LINYVSFINYLCYGVTILGLLLLRWRRPAlhRPIKVNLLIPVAYLVFWAFLLVFSFIS 417
Cdd:pfam00324 354 fnfLLAISGLSGLIVWGLISLSHLRFRKAFKY--QGRSIDELPFKAPLGPLGVILGLAAII 412
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 216-372 2.77e-07

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 52.90  E-value: 2.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 216 FAFSGWNFLNYVTEEMVDARKNLPRAIFISIpLVTFVYTFTNIAYFTAMSPQELLSSNA-VAVTFGEKLLGYFSWVMPVS 294
Cdd:TIGR00906 242 FAFIGFDAIATTGEEVKNPQRAIPIGIVTSL-LVCFVAYFLMSAALTLMMPYYLLDPDApFPVAFEYVGWDPAKYIVAVG 320

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370475509 295 VALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCY 372
Cdd:TIGR00906 321 ALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAY 398
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
136-365 3.83e-05

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 45.88  E-value: 3.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 136 VLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRP----SNAFAF--WMTPSVGHLAL 209
Cdd:COG1113   131 VWALVFLVLLTAINLLSVKLFGEFEFWFALIKVVAIVAFIVVGLLLIFFGFGLPGGPpaglSNLWDHggFFPNGIGGVLA 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 210 AFLQGSFAFSGwnflnyvTE-------EMVDARKNLPRAIfISIPL-VTFVYTFTnIAYFTAMSP-QELLSSNAVAVTFG 280
Cdd:COG1113   211 ALQIVVFAFGG-------IElvgiaaaEAKDPEKTIPKAI-NSVIWrILLFYVGS-LFVILALVPwNQIGAGGSPFVTVF 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 281 EKL-LGYFSWVMPVSV---ALSTfggINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHcTPIPALLVccgaTAVIMLVGd 356
Cdd:COG1113   282 SLLgIPAAAGIMNFVVltaALSS---LNSGLYSTSRMLYSLAERGDAPKFFGKLSKRG-VPVRAILL----SAVVLLIG- 352


                  ....*....
gi 1370475509 357 tyTLINYVS 365
Cdd:COG1113   353 --VVLNYLL 359
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 211-345 9.52e-05

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 44.97  E-value: 9.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 211 FLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFT------NIAYftaMSPQELLSSNAVAV------- 277
Cdd:TIGR00913 203 FVTAAFSFGGTELVALTAGEAANPRKSIPRAAKRTFWRILVFYILTlfligfLVPY---NDPRLLSSSSSSDSaaspfvi 279

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370475509 278 ---TFGEKLLGYFswvMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHvRHCTPIPALLVCC 345
Cdd:TIGR00913 280 aiqNHGIKVLPHI---FNAVILISVLSAANSSLYASSRTLYALAHQGLAPKIFAYVD-RRGVPYVAVIVSS 346
PRK11021 PRK11021
putative transporter; Provisional
 142-355 1.43e-04

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 44.13  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 142 LMLLTWVNSSSVRWATRIQdmftggKLLALSLIIGVGLLqIFQGhfeELRPSNAFafWMTPSVGHLALAFLQGSFAFsgW 221
Cdd:PRK11021  123 LALLWLLNLRGASSSANLQ------TVIALLIVALVVAI-WWAG---DIKPADIP--FPAPGSIEWSGLFAALGVMF--W 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 222 NFLN-----YVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLG-YFSWVMPVSV 295
Cdd:PRK11021  189 CFVGieafaHLASEFKNPERDFPRALMIGLLLAGLVYWACTVVVLHFPAYGDKQAAAASLPGIFVQLFGgYALWVICVIG 268

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 296 ALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHvRHCTPIPALLVCCGATAVIMLVG 355
Cdd:PRK11021  269 YLACFASVNIYTQSFARLVWSQAREGRPPSYLARLS-ARGVPVNALNAVLGCCAVSILLI 327
PRK10249 PRK10249
phenylalanine transporter; Provisional
 130-354 1.55e-04

phenylalanine transporter; Provisional


Pssm-ID: 236667  Cd Length: 458  Bit Score: 44.21  E-value: 1.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 130 PTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGH------FEELRPSNAFafwMTPS 203
Cdd:PRK10249  131 PDVPTWIWAAAFFIIINAVNLVNVRLYGETEFWFALIKVLAIIGMIGFGLWLLFSGHggekasIDNLWRYGGF---FATG 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 204 VGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYtFTNIAYFTAMSPQELLSSNA--VAVTFGE 281
Cdd:PRK10249  208 WNGLILSLAVIMFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFY-IGSLVVLLALYPWVEVKSNSspFVMIFHN 286

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370475509 282 KLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHvRHCTPIPALLVCCGATAVIMLV 354
Cdd:PRK10249  287 LDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTRVS-RRGVPINSLMLSGAITSLVVLI 358
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
130-354 7.46e-04

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 42.08  E-value: 7.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 130 PTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQghfeeLRPSNA--FAFWMT---PSV 204
Cdd:COG0833   123 PDVPVWIWSLLFLALIFLLNALSVKAFGESEFWFSLIKVITVIAFIIVGLLMIFG-----IIGGHApgFSNFTTgdgPFP 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 205 GHLA---LAFLQGSFAFSGwnflnyvTE-------EMVDARKNLPRAI---FISIpLVTFVYTFTNIAYFTAMSPQELLS 271
Cdd:COG0833   198 GGFLailGVMMIVGFSFQG-------TEligiaagESENPEKTIPKAIrqvFWRI-LLFYILAIFVIAALIPYTDAGVAE 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 272 SNAVAVtFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHvRHCTPIPALLvccgATAVI 351
Cdd:COG0833   270 SPFTLV-FERAGIPYAADIMNAVILTAVLSAGNSGLYASTRMLWSLAKEGMAPKIFAKLN-KRGVPLNALL----ATMAV 343


                  ...
gi 1370475509 352 MLV 354
Cdd:COG0833   344 GLL 346
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 209-355 1.28e-03

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 41.27  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 209 LAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPL-VTFVYTFTNIAYFTAMSPQELLSSnavavTFGEKLLGYF 287
Cdd:TIGR00907 221 LGLLNPAWSMTGYDGTAHMAEEIENPEVVGPRAIIGAVAIgIVTGFCFNIVLFFSMGDIDSLISS-----TTGQPIAQIF 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 288 SWVMP----------VSVALSTFGGINGyLFTYSRLCFSGAREGHLP--SLLAMIHVRHCTPIPALLVCCGATAVIMLVG 355
Cdd:TIGR00907 296 YNALGnkagaifllcLILVTSFFCAITC-MTANSRMIYAFSRDGGLPfsPLWSRVNPRTQVPLNAVWLSAVWIILIGLLG 374
PRK11049 PRK11049
D-alanine/D-serine/glycine permease; Provisional
 130-367 8.32e-03

D-alanine/D-serine/glycine permease; Provisional


Pssm-ID: 236830  Cd Length: 469  Bit Score: 38.56  E-value: 8.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 130 PTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQgHFEElrPSNAFA----FW----MT 201
Cdd:PRK11049  130 PDLSDWVASLAVVLLLLSLNLATVKMFGEMEFWFAMIKIVAIVALIVVGLVMVAM-HFQS--PTGVEAsfahLWndggMF 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 202 PS--VGHLAlAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFiSIPLVtfVYTFTNIAYFTAMSPQELLSSNAVAVTF 279
Cdd:PRK11049  207 PKglSGFFA-GFQIAVFAFVGIELVGTTAAETKDPEKSLPRAIN-SIPIR--IIMFYVFALIVIMSVTPWSSVVPDKSPF 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509 280 GEKLL--------GYFSWVMPVSVALSTFGGIngylFTYSRLCFSGAREGHLPSLLAMIHvRHCTPIPALLVCC----GA 347
Cdd:PRK11049  283 VELFVlvglpaaaSVINFVVLTSAASSANSGV----FSTSRMLFGLAQEGVAPKAFAKLS-KRAVPAKGLTFSCicllGG 357

                         250       260
                  ....*....|....*....|...
gi 1370475509 348 TAVIMLVGD---TYTLINYVSFI 367
Cdd:PRK11049  358 VVLLYVNPSvigAFTLVTTVSAI 380
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
2-84 9.76e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 38.68  E-value: 9.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370475509   2 RPPVGAVPAARAVSSRTDGPTGGRPDRR--GSAGSGDA---AGQR----HGRPHAAAERAREPQACALALPSPR-----D 67
Cdd:PRK07003  518 REDAPAAAAPPAPEARPPTPAAAAPAARagGAAAALDVlrnAGMRvssdRGARAAAAAKPAAAPAAAPKPAAPRvavqvP 597

                          90
                  ....*....|....*..
gi 1370475509  68 RPRRLGAGGAQEGDRAA 84
Cdd:PRK07003  598 TPRARAATGDAPPNGAA 614
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH