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Conserved domains on  [gi|1387232254|ref|XP_024837298|]
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ATP synthase subunit C lysine N-methyltransferase isoform X1 [Bos taurus]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 106779)

class I SAM-dependent methyltransferase catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cfa super family cl34437
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 72-162 1.60e-05

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


The actual alignment was detected with superfamily member COG2230:

Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 43.38  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387232254  72 PATTKQIENVVKMLECRRGP-LVDIGSGDGRIVIAAAKE-GFTAVGYELNPWLVWYSRYRARREGVQASARFYISDLWKV 149
Cdd:COG2230    34 EAQEAKLDLILRKLGLKPGMrVLDIGCGWGGLALYLARRyGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDL 113

                          90
                  ....*....|....
gi 1387232254 150 TFS-QYSNVVIFGV 162
Cdd:COG2230   114 PADgQFDAIVSIGM 127
 
Name Accession Description Interval E-value
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 72-162 1.60e-05

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 43.38  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387232254  72 PATTKQIENVVKMLECRRGP-LVDIGSGDGRIVIAAAKE-GFTAVGYELNPWLVWYSRYRARREGVQASARFYISDLWKV 149
Cdd:COG2230    34 EAQEAKLDLILRKLGLKPGMrVLDIGCGWGGLALYLARRyGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDL 113

                          90
                  ....*....|....
gi 1387232254 150 TFS-QYSNVVIFGV 162
Cdd:COG2230   114 PADgQFDAIVSIGM 127
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 88-123 5.00e-03

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 36.25  E-value: 5.00e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1387232254  88 RRGPLVDIGSGDGRIVIAAAKEGFTAVGYELNPWLV 123
Cdd:pfam13489  22 SPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAI 57
 
Name Accession Description Interval E-value
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 72-162 1.60e-05

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 43.38  E-value: 1.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387232254  72 PATTKQIENVVKMLECRRGP-LVDIGSGDGRIVIAAAKE-GFTAVGYELNPWLVWYSRYRARREGVQASARFYISDLWKV 149
Cdd:COG2230    34 EAQEAKLDLILRKLGLKPGMrVLDIGCGWGGLALYLARRyGVRVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDL 113

                          90
                  ....*....|....
gi 1387232254 150 TFS-QYSNVVIFGV 162
Cdd:COG2230   114 PADgQFDAIVSIGM 127
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 76-146 1.68e-05

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 43.08  E-value: 1.68e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387232254  76 KQIENVVKMLECRRGPLVDIGSGDGRIVIAAAKEGFTAVGYELNPWLVWYSRYRARREGVqasaRFYISDL 146
Cdd:COG2227    12 RRLAALLARLLPAGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNV----DFVQGDL 78
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 79-140 7.71e-04

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 38.44  E-value: 7.71e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387232254  79 ENVVKMLECRRGPLV-DIGSGDGRIVIAAAKEGFTAVGYELNPWLVWYSRYRARREGVQASAR 140
Cdd:COG2226    12 EALLAALGLRPGARVlDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGLNVEFV 74
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 88-123 5.00e-03

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 36.25  E-value: 5.00e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1387232254  88 RRGPLVDIGSGDGRIVIAAAKEGFTAVGYELNPWLV 123
Cdd:pfam13489  22 SPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSPIAI 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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