|
Name |
Accession |
Description |
Interval |
E-value |
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
277-445 |
1.46e-36 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 135.51 E-value: 1.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 277 RTVMTQGVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvLREKRFSLVELVHHFFPE------TKEAGICSFQ 350
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGFDFVFFLPCRELS-RSGNARSLADLLFSQWPEpaapvsEVWAVILELP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 351 HlQVLFIFDGLDECRLLLDFHNTQVltdvtvstSVHVLLTNLIRGKLLPCARLWITTRPAAANQIPSDCVDL-VTEVRGF 429
Cdd:pfam05729 80 E-RLLLILDGLDELVSDLGQLDGPC--------PVLTLLSSLLRKKLLPGASLLLTVRPDALRDLRRGLEEPrYLEVRGF 150
|
170
....*....|....*.
gi 1591507915 430 TDPQKEEYFRRRFREE 445
Cdd:pfam05729 151 SESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
591-718 |
1.55e-33 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 125.10 E-value: 1.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 591 HLSVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSsledfLKRVMEKSLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLL 670
Cdd:pfam17776 1 HLSFQEFFAALFYVLSFKEEKSNPLKEFFGLRKRES-----LKSLLDKALKSKNGHLDLFLRFLFGLLNEENQRLLEGLL 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1591507915 671 GqTENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQE 718
Cdd:pfam17776 76 G-CKLSSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| FISNA |
pfam14484 |
Fish-specific NACHT associated domain; This domain is frequently found associated with the ... |
196-267 |
3.08e-33 |
|
Fish-specific NACHT associated domain; This domain is frequently found associated with the NACHT domain (pfam05729) in fish and other vertebrates.
:
Pssm-ID: 464185 [Multi-domain] Cd Length: 72 Bit Score: 122.34 E-value: 3.08e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1591507915 196 LKSNLKQKFQCVFEGIAKAGEPTLLNQIYTELYITEGGTAGVNKDHEVRQIEAASRKAHRPETPIRPADLFK 267
Cdd:pfam14484 1 LKSNLKKKFQCIFEGNAKGGESTLLNEIYTELYITEGESGEVNEEHEVRQIEAASKKPESEETPIRCEDIFK 72
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
283-942 |
2.71e-29 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
:
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 126.07 E-value: 2.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 283 GVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvlreKRFSLVELVHHFFPETKEAGICSFQHL----QVLFIF 358
Cdd:COG5635 187 GEPGSGKTTLLRYLALELAERYLDAEDPIPILIELRDLA----EEASLEDLLAEALEKRGGEPEDALERLlrngRLLLLL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 359 DGLDEcrLLLDFHNTQVLTDvtvstsvhvlLTNLIRGklLPCARLWITTRPAAAnqiPSDCVDLVTEVR--GFTDPQKEE 436
Cdd:COG5635 263 DGLDE--VPDEADRDEVLNQ----------LRRFLER--YPKARVIITSRPEGY---DSSELEGFEVLElaPLSDEQIEE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 437 YFRRRFRE-EEQASRIISHIKTSRSLHIMCHIPVFCWITAGVLedmletREGGELPRTLTEMYIHLlvVQTKVKRVKYEG 515
Cdd:COG5635 326 FLKKWFEAtERKAERLLEALEENPELRELARNPLLLTLLALLL------RERGELPDTRAELYEQF--VELLLERWDEQR 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 516 GAETDPHWSPEsrEMIRSLGKLAFEQLQKGNLIFYESDLTECGIDIRAASVYSGLFTQIFKEERGL---YQDKVFCFIHL 592
Cdd:COG5635 398 GLTIYRELSRE--ELRELLSELALAMQENGRTEFAREELEEILREYLGRRKDAEALLDELLLRTGLlveRGEGRYSFAHR 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 593 SVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSSLEDFLKRvmeksLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLLGQ 672
Cdd:COG5635 476 SFQEYLAARALVEELDEELLELLAEHLEDPRWREVLLLLAGL-----LDDVKQIKELIDALLARDDAAALALAAALLLAL 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 673 TENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQEIQEFLQSGTRSEKGLSEIHCSALAYMLQMSEEVL 752
Cdd:COG5635 551 LLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLLLLLLALALLLALLLLLLL 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 753 EELDLSKYNTSWEGRQRLIPAVRNCRKAQLSDCGLSETHCEVV-----ASALKSNPSHLTQLDLSWINLQDSGVEQLCSG 827
Cdd:COG5635 631 LLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLlllllAELLLALLALASLLLLLLLALALALALLLLAV 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 828 LQSPHCSLQTLRLERCSLSEISCAALVSALKSNPSHLRHLDLSWNDLQDSGVEQLCGFLQSPGCRLQTLGLKRCSLSEIS 907
Cdd:COG5635 711 LLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLASLLLALLLLSLLLLLVLLLALALLAS 790
|
650 660 670
....*....|....*....|....*....|....*
gi 1591507915 908 CAALASALKSNPSHLTELDLSLNHLQESGVEQLLD 942
Cdd:COG5635 791 LLLALLLLILLLVLLGSLLLLRLLDDLALLLLLAL 825
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
277-445 |
1.46e-36 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 135.51 E-value: 1.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 277 RTVMTQGVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvLREKRFSLVELVHHFFPE------TKEAGICSFQ 350
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGFDFVFFLPCRELS-RSGNARSLADLLFSQWPEpaapvsEVWAVILELP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 351 HlQVLFIFDGLDECRLLLDFHNTQVltdvtvstSVHVLLTNLIRGKLLPCARLWITTRPAAANQIPSDCVDL-VTEVRGF 429
Cdd:pfam05729 80 E-RLLLILDGLDELVSDLGQLDGPC--------PVLTLLSSLLRKKLLPGASLLLTVRPDALRDLRRGLEEPrYLEVRGF 150
|
170
....*....|....*.
gi 1591507915 430 TDPQKEEYFRRRFREE 445
Cdd:pfam05729 151 SESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
591-718 |
1.55e-33 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 125.10 E-value: 1.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 591 HLSVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSsledfLKRVMEKSLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLL 670
Cdd:pfam17776 1 HLSFQEFFAALFYVLSFKEEKSNPLKEFFGLRKRES-----LKSLLDKALKSKNGHLDLFLRFLFGLLNEENQRLLEGLL 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1591507915 671 GqTENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQE 718
Cdd:pfam17776 76 G-CKLSSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| FISNA |
pfam14484 |
Fish-specific NACHT associated domain; This domain is frequently found associated with the ... |
196-267 |
3.08e-33 |
|
Fish-specific NACHT associated domain; This domain is frequently found associated with the NACHT domain (pfam05729) in fish and other vertebrates.
Pssm-ID: 464185 [Multi-domain] Cd Length: 72 Bit Score: 122.34 E-value: 3.08e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1591507915 196 LKSNLKQKFQCVFEGIAKAGEPTLLNQIYTELYITEGGTAGVNKDHEVRQIEAASRKAHRPETPIRPADLFK 267
Cdd:pfam14484 1 LKSNLKKKFQCIFEGNAKGGESTLLNEIYTELYITEGESGEVNEEHEVRQIEAASKKPESEETPIRCEDIFK 72
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
283-942 |
2.71e-29 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 126.07 E-value: 2.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 283 GVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvlreKRFSLVELVHHFFPETKEAGICSFQHL----QVLFIF 358
Cdd:COG5635 187 GEPGSGKTTLLRYLALELAERYLDAEDPIPILIELRDLA----EEASLEDLLAEALEKRGGEPEDALERLlrngRLLLLL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 359 DGLDEcrLLLDFHNTQVLTDvtvstsvhvlLTNLIRGklLPCARLWITTRPAAAnqiPSDCVDLVTEVR--GFTDPQKEE 436
Cdd:COG5635 263 DGLDE--VPDEADRDEVLNQ----------LRRFLER--YPKARVIITSRPEGY---DSSELEGFEVLElaPLSDEQIEE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 437 YFRRRFRE-EEQASRIISHIKTSRSLHIMCHIPVFCWITAGVLedmletREGGELPRTLTEMYIHLlvVQTKVKRVKYEG 515
Cdd:COG5635 326 FLKKWFEAtERKAERLLEALEENPELRELARNPLLLTLLALLL------RERGELPDTRAELYEQF--VELLLERWDEQR 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 516 GAETDPHWSPEsrEMIRSLGKLAFEQLQKGNLIFYESDLTECGIDIRAASVYSGLFTQIFKEERGL---YQDKVFCFIHL 592
Cdd:COG5635 398 GLTIYRELSRE--ELRELLSELALAMQENGRTEFAREELEEILREYLGRRKDAEALLDELLLRTGLlveRGEGRYSFAHR 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 593 SVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSSLEDFLKRvmeksLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLLGQ 672
Cdd:COG5635 476 SFQEYLAARALVEELDEELLELLAEHLEDPRWREVLLLLAGL-----LDDVKQIKELIDALLARDDAAALALAAALLLAL 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 673 TENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQEIQEFLQSGTRSEKGLSEIHCSALAYMLQMSEEVL 752
Cdd:COG5635 551 LLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLLLLLLALALLLALLLLLLL 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 753 EELDLSKYNTSWEGRQRLIPAVRNCRKAQLSDCGLSETHCEVV-----ASALKSNPSHLTQLDLSWINLQDSGVEQLCSG 827
Cdd:COG5635 631 LLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLlllllAELLLALLALASLLLLLLLALALALALLLLAV 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 828 LQSPHCSLQTLRLERCSLSEISCAALVSALKSNPSHLRHLDLSWNDLQDSGVEQLCGFLQSPGCRLQTLGLKRCSLSEIS 907
Cdd:COG5635 711 LLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLASLLLALLLLSLLLLLVLLLALALLAS 790
|
650 660 670
....*....|....*....|....*....|....*
gi 1591507915 908 CAALASALKSNPSHLTELDLSLNHLQESGVEQLLD 942
Cdd:COG5635 791 LLLALLLLILLLVLLGSLLLLRLLDDLALLLLLAL 825
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
729-957 |
9.17e-29 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 117.84 E-value: 9.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 729 SEKGLSEIHCSALAYMLQmSEEVLEELDLSKYNTSWEGR--QRLIPAVRNCRKAQ---LSDCGLSETHCEVVASALKSnp 803
Cdd:cd00116 31 EGNTLGEEAAKALASALR-PQPSLKELCLSLNETGRIPRglQSLLQGLTKGCGLQeldLSDNALGPDGCGVLESLLRS-- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 804 SHLTQLDLSWINLQDSGVEQLCSGLQSPHCSLQTLRLERCSLSEISCAALVSALKSNPShLRHLDLSWNDLQDSGVEQLC 883
Cdd:cd00116 108 SSLQELKLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKALRANRD-LKELNLANNGIGDAGIRALA 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1591507915 884 -GFLQSpgCRLQTLGLKRCSLSEISCAALASALKSNPShLTELDLSLNHLQESGVEQLLDLKQSPACSLQTVRWW 957
Cdd:cd00116 187 eGLKAN--CNLEVLDLNNNGLTDEGASALAETLASLKS-LEVLNLGDNNLTDAGAAALASALLSPNISLLTLSLS 258
|
|
| NOD2_WH |
pfam17779 |
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular ... |
529-589 |
1.88e-14 |
|
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular function is not known.
Pssm-ID: 465501 Cd Length: 57 Bit Score: 68.36 E-value: 1.88e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1591507915 529 EMIRSLGKLAFEQLQKGNLIFYESDLTECGIDIraASVYSGLFTQIFKEErgLYQDKVFCF 589
Cdd:pfam17779 1 KLLLKLGKLAFEGLWKKKLVFSEEDLKEYGLDE--SDLSSGLLTEILQKD--LGCEKVYSF 57
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
277-445 |
1.46e-36 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 135.51 E-value: 1.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 277 RTVMTQGVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvLREKRFSLVELVHHFFPE------TKEAGICSFQ 350
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGFDFVFFLPCRELS-RSGNARSLADLLFSQWPEpaapvsEVWAVILELP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 351 HlQVLFIFDGLDECRLLLDFHNTQVltdvtvstSVHVLLTNLIRGKLLPCARLWITTRPAAANQIPSDCVDL-VTEVRGF 429
Cdd:pfam05729 80 E-RLLLILDGLDELVSDLGQLDGPC--------PVLTLLSSLLRKKLLPGASLLLTVRPDALRDLRRGLEEPrYLEVRGF 150
|
170
....*....|....*.
gi 1591507915 430 TDPQKEEYFRRRFREE 445
Cdd:pfam05729 151 SESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
591-718 |
1.55e-33 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 125.10 E-value: 1.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 591 HLSVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSsledfLKRVMEKSLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLL 670
Cdd:pfam17776 1 HLSFQEFFAALFYVLSFKEEKSNPLKEFFGLRKRES-----LKSLLDKALKSKNGHLDLFLRFLFGLLNEENQRLLEGLL 75
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1591507915 671 GqTENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQE 718
Cdd:pfam17776 76 G-CKLSSEIKQELLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| FISNA |
pfam14484 |
Fish-specific NACHT associated domain; This domain is frequently found associated with the ... |
196-267 |
3.08e-33 |
|
Fish-specific NACHT associated domain; This domain is frequently found associated with the NACHT domain (pfam05729) in fish and other vertebrates.
Pssm-ID: 464185 [Multi-domain] Cd Length: 72 Bit Score: 122.34 E-value: 3.08e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1591507915 196 LKSNLKQKFQCVFEGIAKAGEPTLLNQIYTELYITEGGTAGVNKDHEVRQIEAASRKAHRPETPIRPADLFK 267
Cdd:pfam14484 1 LKSNLKKKFQCIFEGNAKGGESTLLNEIYTELYITEGESGEVNEEHEVRQIEAASKKPESEETPIRCEDIFK 72
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
283-942 |
2.71e-29 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 126.07 E-value: 2.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 283 GVAGIGKTVLTQKFSLDWAEDKDHQDVQLTFPFTFRELNvlreKRFSLVELVHHFFPETKEAGICSFQHL----QVLFIF 358
Cdd:COG5635 187 GEPGSGKTTLLRYLALELAERYLDAEDPIPILIELRDLA----EEASLEDLLAEALEKRGGEPEDALERLlrngRLLLLL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 359 DGLDEcrLLLDFHNTQVLTDvtvstsvhvlLTNLIRGklLPCARLWITTRPAAAnqiPSDCVDLVTEVR--GFTDPQKEE 436
Cdd:COG5635 263 DGLDE--VPDEADRDEVLNQ----------LRRFLER--YPKARVIITSRPEGY---DSSELEGFEVLElaPLSDEQIEE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 437 YFRRRFRE-EEQASRIISHIKTSRSLHIMCHIPVFCWITAGVLedmletREGGELPRTLTEMYIHLlvVQTKVKRVKYEG 515
Cdd:COG5635 326 FLKKWFEAtERKAERLLEALEENPELRELARNPLLLTLLALLL------RERGELPDTRAELYEQF--VELLLERWDEQR 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 516 GAETDPHWSPEsrEMIRSLGKLAFEQLQKGNLIFYESDLTECGIDIRAASVYSGLFTQIFKEERGL---YQDKVFCFIHL 592
Cdd:COG5635 398 GLTIYRELSRE--ELRELLSELALAMQENGRTEFAREELEEILREYLGRRKDAEALLDELLLRTGLlveRGEGRYSFAHR 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 593 SVQEFLAALHLILCYTNKTTEGLEDFLGDDYRHSSLEDFLKRvmeksLQSKHGHLDLVVRFLHGLSLQSNQRLLEGLLGQ 672
Cdd:COG5635 476 SFQEYLAARALVEELDEELLELLAEHLEDPRWREVLLLLAGL-----LDDVKQIKELIDALLARDDAAALALAAALLLAL 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 673 TENSPETIQTVINNLKKMNTDEISPDRSINIFHCLMEMNELSVHQEIQEFLQSGTRSEKGLSEIHCSALAYMLQMSEEVL 752
Cdd:COG5635 551 LLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLLLLLLALALLLALLLLLLL 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 753 EELDLSKYNTSWEGRQRLIPAVRNCRKAQLSDCGLSETHCEVV-----ASALKSNPSHLTQLDLSWINLQDSGVEQLCSG 827
Cdd:COG5635 631 LLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLlllllAELLLALLALASLLLLLLLALALALALLLLAV 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 828 LQSPHCSLQTLRLERCSLSEISCAALVSALKSNPSHLRHLDLSWNDLQDSGVEQLCGFLQSPGCRLQTLGLKRCSLSEIS 907
Cdd:COG5635 711 LLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLASLLLALLLLSLLLLLVLLLALALLAS 790
|
650 660 670
....*....|....*....|....*....|....*
gi 1591507915 908 CAALASALKSNPSHLTELDLSLNHLQESGVEQLLD 942
Cdd:COG5635 791 LLLALLLLILLLVLLGSLLLLRLLDDLALLLLLAL 825
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
729-957 |
9.17e-29 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 117.84 E-value: 9.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 729 SEKGLSEIHCSALAYMLQmSEEVLEELDLSKYNTSWEGR--QRLIPAVRNCRKAQ---LSDCGLSETHCEVVASALKSnp 803
Cdd:cd00116 31 EGNTLGEEAAKALASALR-PQPSLKELCLSLNETGRIPRglQSLLQGLTKGCGLQeldLSDNALGPDGCGVLESLLRS-- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 804 SHLTQLDLSWINLQDSGVEQLCSGLQSPHCSLQTLRLERCSLSEISCAALVSALKSNPShLRHLDLSWNDLQDSGVEQLC 883
Cdd:cd00116 108 SSLQELKLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKALRANRD-LKELNLANNGIGDAGIRALA 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1591507915 884 -GFLQSpgCRLQTLGLKRCSLSEISCAALASALKSNPShLTELDLSLNHLQESGVEQLLDLKQSPACSLQTVRWW 957
Cdd:cd00116 187 eGLKAN--CNLEVLDLNNNGLTDEGASALAETLASLKS-LEVLNLGDNNLTDAGAAALASALLSPNISLLTLSLS 258
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
769-940 |
2.30e-26 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 110.91 E-value: 2.30e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 769 RLIPAVRNCRKAQLSDCGLSETHCEVVASALKSNPShLTQLDLSWINLQ--DSGVEQLCSGLQSPhCSLQTLRLERCSLS 846
Cdd:cd00116 17 ELLPKLLCLQVLRLEGNTLGEEAAKALASALRPQPS-LKELCLSLNETGriPRGLQSLLQGLTKG-CGLQELDLSDNALG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 847 EISCAALVSALKSnpSHLRHLDLSWNDLQDSGVEQLCGFLQSPGCRLQTLGLKRCSLSEISCAALASALKSNPShLTELD 926
Cdd:cd00116 95 PDGCGVLESLLRS--SSLQELKLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKALRANRD-LKELN 171
|
170
....*....|....
gi 1591507915 927 LSLNHLQESGVEQL 940
Cdd:cd00116 172 LANNGIGDAGIRAL 185
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
739-942 |
1.71e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 82.92 E-value: 1.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 739 SALAYMLQMSEEvLEELDLSKYNTSWEGRQRLIPAVRNCRKAQ---LSDCGLSETHCEVVASALKSNPsHLTQLDLSWIN 815
Cdd:COG5238 226 EILAEALKGNKS-LTTLDLSNNQIGDEGVIALAEALKNNTTVEtlyLSGNQIGAEGAIALAKALQGNT-TLTSLDLSVNR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 816 LQDSGVEQLCSGLQSPHcSLQTLRLERCSLSEISCAALVSALKSNPShLRHLDLSWNDLQDSGVEQLCGFLQSPGcRLQT 895
Cdd:COG5238 304 IGDEGAIALAEGLQGNK-TLHTLNLAYNGIGAQGAIALAKALQENTT-LHSLDLSDNQIGDEGAIALAKYLEGNT-TLRE 380
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1591507915 896 LGLKRCSLSEISCAALASALKSNpsHLTELDLSLNHL---QESGVEQLLD 942
Cdd:COG5238 381 LNLGKNNIGKQGAEALIDALQTN--RLHTLILDGNLIgaeAQQRLEQLLE 428
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
668-945 |
3.49e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 82.15 E-value: 3.49e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 668 GLLGQTENSPETIQTVINNLKKMNTDEISPDRSInifhclmeMNELSVHQEIQEF-------LQSGTRSEKGLSEIHCSA 740
Cdd:COG5238 89 LLVVDWEGAEEVSPVALAETATAVATPPPDLRRI--------MAKTLEDSLILYLalprrinLIQVLKDPLGGNAVHLLG 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 741 LA------YMLQMSEEV----LEELDLSKYNTSWEGRQRLIPAVR---NCRKAQLSDCGLSETHCEVVASALKSNPShLT 807
Cdd:COG5238 161 LAarlgllAAISMAKALqnnsVETVYLGCNQIGDEGIEELAEALTqntTVTTLWLKRNPIGDEGAEILAEALKGNKS-LT 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 808 QLDLSWINLQDSGVEQLCSGLQSPHcSLQTLRLERCSLSEISCAALVSALKSNPsHLRHLDLSWNDLQDSGVEQLCGFLQ 887
Cdd:COG5238 240 TLDLSNNQIGDEGVIALAEALKNNT-TVETLYLSGNQIGAEGAIALAKALQGNT-TLTSLDLSVNRIGDEGAIALAEGLQ 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 888 SPGcRLQTLGLKRCSLSEISCAALASALKSNP---------------------------SHLTELDLSLNHLQESGVEQL 940
Cdd:COG5238 318 GNK-TLHTLNLAYNGIGAQGAIALAKALQENTtlhsldlsdnqigdegaialakylegnTTLRELNLGKNNIGKQGAEAL 396
|
....*
gi 1591507915 941 LDLKQ 945
Cdd:COG5238 397 IDALQ 401
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
741-928 |
3.04e-15 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 77.78 E-value: 3.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 741 LAYMLQMSEEVLEELDLSKYNTSWEGRQRL---IPAVRNCRKAQLSDCGLSETHCEVVASALKSNpSHLTQLDLSWINLQ 817
Cdd:cd00116 128 LAKGLKDLPPALEKLVLGRNRLEGASCEALakaLRANRDLKELNLANNGIGDAGIRALAEGLKAN-CNLEVLDLNNNGLT 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 818 DSGVEQLCSGLQSPhCSLQTLRLERCSLSEISCAALVSALKSNPSHLRHLDLSWNDLQDSGVEQLCGFLQSpGCRLQTLG 897
Cdd:cd00116 207 DEGASALAETLASL-KSLEVLNLGDNNLTDAGAAALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAE-KESLLELD 284
|
170 180 190
....*....|....*....|....*....|.
gi 1591507915 898 LKRCSLSEISCAALASALKSNPSHLTELDLS 928
Cdd:cd00116 285 LRGNKFGEEGAQLLAESLLEPGNELESLWVK 315
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
752-903 |
7.09e-15 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 76.63 E-value: 7.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 752 LEELDLSKYNTSWEGRQRLIPAVR-NC--RKAQLSDCGLSETHCEVVASALKSNPShLTQLDLSWINLQDSGVEQLCSGL 828
Cdd:cd00116 167 LKELNLANNGIGDAGIRALAEGLKaNCnlEVLDLNNNGLTDEGASALAETLASLKS-LEVLNLGDNNLTDAGAAALASAL 245
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1591507915 829 QSPHCSLQTLRLERCSLSEISCAALVSALKSNPSHLRhLDLSWNDLQDSGVEQLCGFLQSPGCRLQTLGLKRCSL 903
Cdd:cd00116 246 LSPNISLLTLSLSCNDITDDGAKDLAEVLAEKESLLE-LDLRGNKFGEEGAQLLAESLLEPGNELESLWVKDDSF 319
|
|
| NOD2_WH |
pfam17779 |
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular ... |
529-589 |
1.88e-14 |
|
NOD2 winged helix domain; This winged helix domain is found in the NOD2 protein. Its molecular function is not known.
Pssm-ID: 465501 Cd Length: 57 Bit Score: 68.36 E-value: 1.88e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1591507915 529 EMIRSLGKLAFEQLQKGNLIFYESDLTECGIDIraASVYSGLFTQIFKEErgLYQDKVFCF 589
Cdd:pfam17779 1 KLLLKLGKLAFEGLWKKKLVFSEEDLKEYGLDE--SDLSSGLLTEILQKD--LGCEKVYSF 57
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
791-947 |
1.43e-07 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 55.18 E-value: 1.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 791 HCEVVASALKSNPSHLT--QLDLSWINLQDSGVEQ---------LCSGLQSPH-CSLQTLRLERCSLSEISCAALVSALK 858
Cdd:COG5238 99 EVSPVALAETATAVATPppDLRRIMAKTLEDSLILylalprrinLIQVLKDPLgGNAVHLLGLAARLGLLAAISMAKALQ 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 859 SNpsHLRHLDLSWNDLQDSGVEQLCGFLQSpGCRLQTLGLKRCSLSEISCAALASALKSNPShLTELDLSLNHLQESGVE 938
Cdd:COG5238 179 NN--SVETVYLGCNQIGDEGIEELAEALTQ-NTTVTTLWLKRNPIGDEGAEILAEALKGNKS-LTTLDLSNNQIGDEGVI 254
|
....*....
gi 1591507915 939 QLLDLKQSP 947
Cdd:COG5238 255 ALAEALKNN 263
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
801-934 |
1.16e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 48.78 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 801 SNPSHLTQL-DLSWINLQDSGVEQLCSGLQSPHcSLQTLRLERCSLSEIScaalvSALKSNPsHLRHLDLSWNDLQD--S 877
Cdd:COG4886 104 SGNEELSNLtNLESLDLSGNQLTDLPEELANLT-NLKELDLSNNQLTDLP-----EPLGNLT-NLKSLDLSNNQLTDlpE 176
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1591507915 878 GVEQLCgflqspgcRLQTLGLKRCSLSEIScAALasalkSNPSHLTELDLSLNHLQE 934
Cdd:COG4886 177 ELGNLT--------NLKELDLSNNQITDLP-EPL-----GNLTNLEELDLSGNQLTD 219
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
752-945 |
1.61e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 48.39 E-value: 1.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 752 LEELDLSKYNTSwegrqRLIPAVRNCRKaqLSDCGLSETHCEVVASALKSNPsHLTQLDLSWINLQD--SGVEQLCSglq 829
Cdd:COG4886 138 LKELDLSNNQLT-----DLPEPLGNLTN--LKSLDLSNNQLTDLPEELGNLT-NLKELDLSNNQITDlpEPLGNLTN--- 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1591507915 830 sphcsLQTLRLERCSLSEISCAalVSALKSnpshLRHLDLSWNDLQDsgVEQLCGFLQspgcrLQTLGLKRCSLSEISCA 909
Cdd:COG4886 207 -----LEELDLSGNQLTDLPEP--LANLTN----LETLDLSNNQLTD--LPELGNLTN-----LEELDLSNNQLTDLPPL 268
|
170 180 190
....*....|....*....|....*....|....*.
gi 1591507915 910 AlasalksNPSHLTELDLSLNHLQESGVEQLLDLKQ 945
Cdd:COG4886 269 A-------NLTNLKTLDLSNNQLTDLKLKELELLLG 297
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
862-883 |
2.82e-04 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 38.76 E-value: 2.82e-04
|
| |
