|
Name |
Accession |
Description |
Interval |
E-value |
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
639-782 |
4.31e-39 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 141.31 E-value: 4.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 639 QFHAFVSYSGHDsaWVKNELLPNLEKD--DIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYF 716
Cdd:smart00255 1 EYDVFISYSGKE--DVRNEFLSHLLEKlrGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720413011 717 AHHNLFHEGSDNLILILLAPIPQYsIPTNYHKLKTLMsRRTYLEWPTEKNKHglFWANLRASINVK 782
Cdd:smart00255 79 ALENALEEGGLRVIPIFYEVIPSD-VRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYAVPSK 140
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
640-786 |
1.69e-23 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 97.82 E-value: 1.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 640 FHAFVSYSGHDS-AWVKNELLPNLEKDDIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYFAH 718
Cdd:pfam01582 1 YDVFLSFRGSDTrEWFVSHLLKELKQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720413011 719 HNLFhEGSDNLILILLAPIPQY------SIPTNYHKLKTLMSRRTYLEWPTEKNKHGLFWANLRASINVKLVNQ 786
Cdd:pfam01582 81 ECAL-DLGQKVIPIFYEVDPSDvrkqtgSFGKAFKKHKKVLTEEKVLKWRGALNEVANIWHSKSVSDESKFWKK 153
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
356-529 |
1.27e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.06 E-value: 1.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 356 VDFTDNLLTDMvFKDCRNLVRLKTLSLQKNQLKNLENIIltsAKMTSLQKLDISQNSLRysdgGIPCAWTQ--SLLVLNL 433
Cdd:COG4886 118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPL---GNLTNLKSLDLSNNQLT----DLPEELGNltNLKELDL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 434 SSNMLT--GSVFRCLPpKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSED 511
Cdd:COG4886 190 SNNQITdlPEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPL 268
|
170
....*....|....*...
gi 1720413011 512 FfqSCQNIRSLTAGNNPF 529
Cdd:COG4886 269 A--NLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
38-156 |
1.38e-11 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 67.27 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 38 NLTRVPKDLPLQT--TTLDLSQNNISELqTSDILSLSKLRVLIMSYNRLQYLNISVFKFnTELEYLDLSHNELKVIlchP 115
Cdd:COG4886 147 QLTDLPEPLGNLTnlKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPEPLGNL-TNLEELDLSGNQLTDL---P 221
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1720413011 116 TV-----SLKHLDLSFNAFDALPickEFGNMSQLQFLGLSGSRVQS 156
Cdd:COG4886 222 EPlanltNLETLDLSNNQLTDLP---ELGNLTNLEELDLSNNQLTD 264
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
527-581 |
1.73e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 51.28 E-value: 1.73e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1720413011 527 NPFQCTCELRDFVKnigWVAREVVEGWPDSYRCDYPESSRGtALRDFHMSPLSCD 581
Cdd:smart00082 1 NPFICDCELRWLLR---WLQANEHLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
377-487 |
1.46e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 55.09 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 377 LKTLSLQKNQLKNLENIIltsakMTSLQKLDISQNSLRYsdggIPCAWTQSLLVLNLSSNMLTgSVFRCLPPKVKVLDLH 456
Cdd:PRK15370 285 LRYLSVYDNSIRTLPAHL-----PSGITHLNVQSNSLTA----LPETLPPGLKTLEAGENALT-SLPASLPPELQVLDVS 354
|
90 100 110
....*....|....*....|....*....|.
gi 1720413011 457 NNRIMSIPKdvTHLQALQELNVASNSLTDLP 487
Cdd:PRK15370 355 KNQITVLPE--TLPPTITTLDVSRNALTNLP 383
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
38-133 |
2.55e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 54.32 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 38 NLTRVPKDLPLQTTTLDLSQNNISELQTSdilSLSKLRVLIMSYNRLQYLNISVfkfNTELEYLDLSHNELKVILCHPTV 117
Cdd:PRK15370 231 QLTSIPATLPDTIQEMELSINRITELPER---LPSALQSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTLPAHLPS 304
|
90
....*....|....*.
gi 1720413011 118 SLKHLDLSFNAFDALP 133
Cdd:PRK15370 305 GITHLNVQSNSLTALP 320
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
51-108 |
5.74e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 5.74e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720413011 51 TTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNEL 108
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
52-448 |
3.73e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 50.62 E-value: 3.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 52 TLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQ-YLNISVFKFnTELEYLDLSHNE--------------LKVILCH-- 114
Cdd:PLN00113 144 TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNL-TSLEFLTLASNQlvgqiprelgqmksLKWIYLGyn 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 115 ------PT-----VSLKHLDLSFNAFDAlPICKEFGNMSQLQFLGLSGSRVQSSSVQLIahLNISKVL-LVLGDAYGEKE 182
Cdd:PLN00113 223 nlsgeiPYeigglTSLNHLDLVYNNLTG-PIPSSLGNLKNLQYLFLYQNKLSGPIPPSI--FSLQKLIsLDLSDNSLSGE 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 183 DPESLrhVSTETLHIVFPSKREFRFLLDVSVS-----------------------------TTIGLELSNIKCVLEDQGC 233
Cdd:PLN00113 300 IPELV--IQLQNLEILHLFSNNFTGKIPVALTslprlqvlqlwsnkfsgeipknlgkhnnlTVLDLSTNNLTGEIPEGLC 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 234 S--------YFLRAL-SKLGKNLKLSNlTLNNVETTWNSFINIL-QIVWHTPVKYF-SISNVKLQGQLAFRMFNYsdTSL 302
Cdd:PLN00113 378 SsgnlfkliLFSNSLeGEIPKSLGACR-SLRRVRLQDNSFSGELpSEFTKLPLVYFlDISNNNLQGRINSRKWDM--PSL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 303 KALSIHQvvtDVFS--FPQSYIYSIFANMNIQNFTMSGThmvhmlCPSQ---VSPFLHVDFTDNLLTDMV---FKDCRNL 374
Cdd:PLN00113 455 QMLSLAR---NKFFggLPDSFGSKRLENLDLSRNQFSGA------VPRKlgsLSELMQLKLSENKLSGEIpdeLSSCKKL 525
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720413011 375 VrlkTLSLQKNQLKNleNIILTSAKMTSLQKLDISQNSLrysDGGIP--CAWTQSLLVLNLSSNMLTGSvfrcLPP 448
Cdd:PLN00113 526 V---SLDLSHNQLSG--QIPASFSEMPVLSQLDLSQNQL---SGEIPknLGNVESLVQVNISHNHLHGS----LPS 589
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
360-529 |
4.99e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.16 E-value: 4.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 360 DNLLTDMvfKDCRNLVRLKTLSLQKNQLKNLENIiltsAKMTSLQKLDISQNSLRYSDGGIPCawtQSLLVLNLSSNmlt 439
Cdd:cd21340 33 DNKITKI--ENLEFLTNLTHLYLQNNQIEKIENL----ENLVNLKKLYLGGNRISVVEGLENL---TNLEELHIENQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 440 gsvfrCLPPKVKvLDLHNNRIMSIpkdvthLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSE--DFFQSCQ 517
Cdd:cd21340 101 -----RLPPGEK-LTFDPRSLAAL------SNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWP 168
|
170
....*....|..
gi 1720413011 518 NIRSLTAGNNPF 529
Cdd:cd21340 169 SLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
448-503 |
1.20e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.59 E-value: 1.20e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 448 PKVKVLDLHNNRIMSIPKDV-THLQALQELNVASNSLTDLPGcGAFS---SLSVLVIDHN 503
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSP-GAFSglpSLRYLDLSGN 59
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
33-163 |
1.32e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.57 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 33 KRPNANLTRVPKDLPLQTTTLDLSQNNISELQTSDILSL----SKLRVLIMSYN------------------RLQYLNIS 90
Cdd:cd00116 122 DRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNgigdagiralaeglkancNLEVLDLN 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 91 --------------VFKFNTELEYLDLSHN--------ELKVILCHPTVSLKHLDLSFN---AFDALPICKEFGNMSQLQ 145
Cdd:cd00116 202 nngltdegasalaeTLASLKSLEVLNLGDNnltdagaaALASALLSPNISLLTLSLSCNditDDGAKDLAEVLAEKESLL 281
|
170
....*....|....*...
gi 1720413011 146 FLGLSGSRVQSSSVQLIA 163
Cdd:cd00116 282 ELDLRGNKFGEEGAQLLA 299
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
639-782 |
4.31e-39 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 141.31 E-value: 4.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 639 QFHAFVSYSGHDsaWVKNELLPNLEKD--DIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYF 716
Cdd:smart00255 1 EYDVFISYSGKE--DVRNEFLSHLLEKlrGYGLCVFIDDFEPGGGDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720413011 717 AHHNLFHEGSDNLILILLAPIPQYsIPTNYHKLKTLMsRRTYLEWPTEKNKHglFWANLRASINVK 782
Cdd:smart00255 79 ALENALEEGGLRVIPIFYEVIPSD-VRKQPGKFRKVF-KKNYLKWPEDEKEQ--FWKKALYAVPSK 140
|
|
| TIR |
pfam01582 |
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ... |
640-786 |
1.69e-23 |
|
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.
Pssm-ID: 396246 [Multi-domain] Cd Length: 165 Bit Score: 97.82 E-value: 1.69e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 640 FHAFVSYSGHDS-AWVKNELLPNLEKDDIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYFAH 718
Cdd:pfam01582 1 YDVFLSFRGSDTrEWFVSHLLKELKQKGIKLFIDDRDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720413011 719 HNLFhEGSDNLILILLAPIPQY------SIPTNYHKLKTLMSRRTYLEWPTEKNKHGLFWANLRASINVKLVNQ 786
Cdd:pfam01582 81 ECAL-DLGQKVIPIFYEVDPSDvrkqtgSFGKAFKKHKKVLTEEKVLKWRGALNEVANIWHSKSVSDESKFWKK 153
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
356-529 |
1.27e-16 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 83.06 E-value: 1.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 356 VDFTDNLLTDMvFKDCRNLVRLKTLSLQKNQLKNLENIIltsAKMTSLQKLDISQNSLRysdgGIPCAWTQ--SLLVLNL 433
Cdd:COG4886 118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPL---GNLTNLKSLDLSNNQLT----DLPEELGNltNLKELDL 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 434 SSNMLT--GSVFRCLPpKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSED 511
Cdd:COG4886 190 SNNQITdlPEPLGNLT-NLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPL 268
|
170
....*....|....*...
gi 1720413011 512 FfqSCQNIRSLTAGNNPF 529
Cdd:COG4886 269 A--NLTNLKTLDLSNNQL 284
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
643-736 |
8.22e-16 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 74.27 E-value: 8.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 643 FVSYSGHDSAWVKnELLPNLEKDDIQICLHERNFVPGKSIVENIINFIEKSYKSIFVLSPHFIQSEWCHYELYFAHHnlF 722
Cdd:pfam13676 2 FISYAGEDRAWAE-WLADALEAAGYRVWLDRWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALA--D 78
|
90
....*....|....
gi 1720413011 723 HEGSDNLILILLAP 736
Cdd:pfam13676 79 PEGRKRLIPVRLEC 92
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
240-543 |
2.44e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 78.82 E-value: 2.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 240 LSKLGKNLKLSNLTLNNVETTWNSFINILQIVWHTPVKYFSISNVKLQGQLAFRMFNYSDTSLKALSIHQVvTDVFSFPQ 319
Cdd:COG4886 25 ILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDL-TNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 320 SYIYSIFANMNIQNFTMSGTHMVHMlcPSQVSPFLH---VDFTDNLLTDmVFKDCRNLVRLKTLSLQKNQLKNLENIIlt 396
Cdd:COG4886 104 SGNEELSNLTNLESLDLSGNQLTDL--PEELANLTNlkeLDLSNNQLTD-LPEPLGNLTNLKSLDLSNNQLTDLPEEL-- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 397 sAKMTSLQKLDISQNSLrySDGGIPCAWTQSLLVLNLSSNMLT---GSVFRClpPKVKVLDLHNNRIMSIPkDVTHLQAL 473
Cdd:COG4886 179 -GNLTNLKELDLSNNQI--TDLPEPLGNLTNLEELDLSGNQLTdlpEPLANL--TNLETLDLSNNQLTDLP-ELGNLTNL 252
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 474 QELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRSLTAGNNPFQCTCELRDFVKNIG 543
Cdd:COG4886 253 EELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTT 322
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
38-156 |
1.38e-11 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 67.27 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 38 NLTRVPKDLPLQT--TTLDLSQNNISELqTSDILSLSKLRVLIMSYNRLQYLNISVFKFnTELEYLDLSHNELKVIlchP 115
Cdd:COG4886 147 QLTDLPEPLGNLTnlKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPEPLGNL-TNLEELDLSGNQLTDL---P 221
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1720413011 116 TV-----SLKHLDLSFNAFDALPickEFGNMSQLQFLGLSGSRVQS 156
Cdd:COG4886 222 EPlanltNLETLDLSNNQLTDLP---ELGNLTNLEELDLSNNQLTD 264
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
327-530 |
7.79e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 58.79 E-value: 7.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 327 ANMNIQNFTMSGTHMVHMLCPSQVSPFLHVDFTDNLLTDMVFKDCRNLVRLKTLSLQKNQLKNLENIILTSAKMTSLQKL 406
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 407 DISQNSLRYSDggipCAWTQSLLVLNLSSNMLTGSVfrclpPKVKVLDLHNNRIMSIPKDVTHLQALQELNVASNSLTDL 486
Cdd:COG4886 81 LLSLLLLGLTD----LGDLTNLTELDLSGNEELSNL-----TNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1720413011 487 P-GCGAFSSLSVLVIDHNSVSH-PSEdfFQSCQNIRSLTAGNNPFQ 530
Cdd:COG4886 152 PePLGNLTNLKSLDLSNNQLTDlPEE--LGNLTNLKELDLSNNQIT 195
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
527-581 |
1.73e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 51.28 E-value: 1.73e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1720413011 527 NPFQCTCELRDFVKnigWVAREVVEGWPDSYRCDYPESSRGtALRDFHMSPLSCD 581
Cdd:smart00082 1 NPFICDCELRWLLR---WLQANEHLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
377-487 |
1.46e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 55.09 E-value: 1.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 377 LKTLSLQKNQLKNLENIIltsakMTSLQKLDISQNSLRYsdggIPCAWTQSLLVLNLSSNMLTgSVFRCLPPKVKVLDLH 456
Cdd:PRK15370 285 LRYLSVYDNSIRTLPAHL-----PSGITHLNVQSNSLTA----LPETLPPGLKTLEAGENALT-SLPASLPPELQVLDVS 354
|
90 100 110
....*....|....*....|....*....|.
gi 1720413011 457 NNRIMSIPKdvTHLQALQELNVASNSLTDLP 487
Cdd:PRK15370 355 KNQITVLPE--TLPPTITTLDVSRNALTNLP 383
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
51-156 |
2.48e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 53.78 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 51 TTLDLSQNNiselqtsDILSLSKLRVLIMSYNRLQYLNISVFKFnTELEYLDLSHNELKVIlchPTV-----SLKHLDLS 125
Cdd:COG4886 99 TELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELANL-TNLKELDLSNNQLTDL---PEPlgnltNLKSLDLS 167
|
90 100 110
....*....|....*....|....*....|.
gi 1720413011 126 FNAFDALPicKEFGNMSQLQFLGLSGSRVQS 156
Cdd:COG4886 168 NNQLTDLP--EELGNLTNLKELDLSNNQITD 196
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
38-133 |
2.55e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 54.32 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 38 NLTRVPKDLPLQTTTLDLSQNNISELQTSdilSLSKLRVLIMSYNRLQYLNISVfkfNTELEYLDLSHNELKVILCHPTV 117
Cdd:PRK15370 231 QLTSIPATLPDTIQEMELSINRITELPER---LPSALQSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTLPAHLPS 304
|
90
....*....|....*.
gi 1720413011 118 SLKHLDLSFNAFDALP 133
Cdd:PRK15370 305 GITHLNVQSNSLTALP 320
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
51-108 |
5.74e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 5.74e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720413011 51 TTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNEL 108
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
377-519 |
1.03e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.39 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 377 LKTLSLQKNQLKNLENIIltsakMTSLQKLDISQNSLRYSDGGIPCAwtqsLLVLNLSSNMLTgSVFRCLPPKVKVLDLH 456
Cdd:PRK15370 222 IKTLYANSNQLTSIPATL-----PDTIQEMELSINRITELPERLPSA----LQSLDLFHNKIS-CLPENLPEELRYLSVY 291
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720413011 457 NNRIMSIPKdvtHL-QALQELNVASNSLTDLPGCGAfSSLSVLVIDHNSVSHPSEDFFQSCQNI 519
Cdd:PRK15370 292 DNSIRTLPA---HLpSGITHLNVQSNSLTALPETLP-PGLKTLEAGENALTSLPASLPPELQVL 351
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
377-506 |
1.34e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.16 E-value: 1.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 377 LKTLSLQKNQL--KNLENIILTSakmTSLQKLDISQNSLrysDGGIPCAWTQSLLVLNLSSNMLTGSVFRCLP--PKVKV 452
Cdd:PLN00113 95 IQTINLSNNQLsgPIPDDIFTTS---SSLRYLNLSNNNF---TGSIPRGSIPNLETLDLSNNMLSGEIPNDIGsfSSLKV 168
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1720413011 453 LDLHNNRIMS-IPKDVTHLQALQELNVASNSLT-DLPG-CGAFSSLSVLVIDHNSVS 506
Cdd:PLN00113 169 LDLGGNVLVGkIPNSLTNLTSLEFLTLASNQLVgQIPReLGQMKSLKWIYLGYNNLS 225
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
72-129 |
3.13e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 3.13e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720413011 72 SKLRVLIMSYNRLQYLNISVFKFNTELEYLDLSHNELKVI---LCHPTVSLKHLDLSFNAF 129
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLspgAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
371-503 |
3.20e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 51.00 E-value: 3.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 371 CRNLVRLKTLSLQKnqlKNLENIILTSA-KMTSLQKLDISQNSLrysDGGIPCA---WTQSLLVLNLSSNMLTGSVFRCL 446
Cdd:PLN00113 65 CNNSSRVVSIDLSG---KNISGKISSAIfRLPYIQTINLSNNQL---SGPIPDDiftTSSSLRYLNLSNNNFTGSIPRGS 138
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 447 PPKVKVLDLHNNRIM-SIPKDVTHLQALQELNVASNSLT-DLPG-CGAFSSLSVLVIDHN 503
Cdd:PLN00113 139 IPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNsLTNLTSLEFLTLASN 198
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
52-448 |
3.73e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 50.62 E-value: 3.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 52 TLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQ-YLNISVFKFnTELEYLDLSHNE--------------LKVILCH-- 114
Cdd:PLN00113 144 TLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNL-TSLEFLTLASNQlvgqiprelgqmksLKWIYLGyn 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 115 ------PT-----VSLKHLDLSFNAFDAlPICKEFGNMSQLQFLGLSGSRVQSSSVQLIahLNISKVL-LVLGDAYGEKE 182
Cdd:PLN00113 223 nlsgeiPYeigglTSLNHLDLVYNNLTG-PIPSSLGNLKNLQYLFLYQNKLSGPIPPSI--FSLQKLIsLDLSDNSLSGE 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 183 DPESLrhVSTETLHIVFPSKREFRFLLDVSVS-----------------------------TTIGLELSNIKCVLEDQGC 233
Cdd:PLN00113 300 IPELV--IQLQNLEILHLFSNNFTGKIPVALTslprlqvlqlwsnkfsgeipknlgkhnnlTVLDLSTNNLTGEIPEGLC 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 234 S--------YFLRAL-SKLGKNLKLSNlTLNNVETTWNSFINIL-QIVWHTPVKYF-SISNVKLQGQLAFRMFNYsdTSL 302
Cdd:PLN00113 378 SsgnlfkliLFSNSLeGEIPKSLGACR-SLRRVRLQDNSFSGELpSEFTKLPLVYFlDISNNNLQGRINSRKWDM--PSL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 303 KALSIHQvvtDVFS--FPQSYIYSIFANMNIQNFTMSGThmvhmlCPSQ---VSPFLHVDFTDNLLTDMV---FKDCRNL 374
Cdd:PLN00113 455 QMLSLAR---NKFFggLPDSFGSKRLENLDLSRNQFSGA------VPRKlgsLSELMQLKLSENKLSGEIpdeLSSCKKL 525
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720413011 375 VrlkTLSLQKNQLKNleNIILTSAKMTSLQKLDISQNSLrysDGGIP--CAWTQSLLVLNLSSNMLTGSvfrcLPP 448
Cdd:PLN00113 526 V---SLDLSHNQLSG--QIPASFSEMPVLSQLDLSQNQL---SGEIPknLGNVESLVQVNISHNHLHGS----LPS 589
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
360-529 |
4.99e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 45.16 E-value: 4.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 360 DNLLTDMvfKDCRNLVRLKTLSLQKNQLKNLENIiltsAKMTSLQKLDISQNSLRYSDGGIPCawtQSLLVLNLSSNmlt 439
Cdd:cd21340 33 DNKITKI--ENLEFLTNLTHLYLQNNQIEKIENL----ENLVNLKKLYLGGNRISVVEGLENL---TNLEELHIENQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 440 gsvfrCLPPKVKvLDLHNNRIMSIpkdvthLQALQELNVASNSLTDLPGCGAFSSLSVLVIDHNSVSHPSE--DFFQSCQ 517
Cdd:cd21340 101 -----RLPPGEK-LTFDPRSLAAL------SNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWP 168
|
170
....*....|..
gi 1720413011 518 NIRSLTAGNNPF 529
Cdd:cd21340 169 SLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
448-503 |
1.20e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 40.59 E-value: 1.20e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 448 PKVKVLDLHNNRIMSIPKDV-THLQALQELNVASNSLTDLPGcGAFS---SLSVLVIDHN 503
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSP-GAFSglpSLRYLDLSGN 59
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
373-487 |
1.75e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 43.62 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 373 NLVRLKTLSLQKNQLKNLENIiltsAKMTSLQKLDISQNSLR-----YSDGGIPCAWTQSLLVLNLSSNMLTG-SVFRCL 446
Cdd:cd21340 66 NLVNLKKLYLGGNRISVVEGL----ENLTNLEELHIENQRLPpgeklTFDPRSLAALSNSLRVLNISGNNIDSlEPLAPL 141
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1720413011 447 pPKVKVLDLHNNRIMSIPK---DVTHLQALQELNVASNSLTDLP 487
Cdd:cd21340 142 -RNLEQLDASNNQISDLEElldLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
355-487 |
1.96e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 44.27 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 355 HVDFTDNLLTDM---VFKDCRNLVRLKTLSLQKNQL-KNLENIILTSAKMTS--LQKLDISQNSLrYSDGGIPCA----W 424
Cdd:cd00116 85 ELDLSDNALGPDgcgVLESLLRSSSLQELKLNNNGLgDRGLRLLAKGLKDLPpaLEKLVLGRNRL-EGASCEALAkalrA 163
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720413011 425 TQSLLVLNLSSNMLTGSVFRCLPP------KVKVLDLHNNRIMS-----IPKDVTHLQALQELNVASNSLTDLP 487
Cdd:cd00116 164 NRDLKELNLANNGIGDAGIRALAEglkancNLEVLDLNNNGLTDegasaLAETLASLKSLEVLNLGDNNLTDAG 237
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
51-540 |
2.07e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 44.84 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 51 TTLDLSQNNISELQTSDILSLSKLRVLIMSYNRLQY-LNISVFKFNTELEYLDLSHNELKVILCHPTVS-LKHLDLSFNA 128
Cdd:PLN00113 72 VSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGpIPDDIFTTSSSLRYLNLSNNNFTGSIPRGSIPnLETLDLSNNM 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 129 FDAlPICKEFGNMSQLQFLGLSGSrvqsssvQLIAHLniskvllvlgdaygekedPESLRHVstetlhivfpSKREFRFL 208
Cdd:PLN00113 152 LSG-EIPNDIGSFSSLKVLDLGGN-------VLVGKI------------------PNSLTNL----------TSLEFLTL 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 209 LDVSVSTTIGLELSNIkcvledqgcsyflralsklgKNLKLSNLTLNNvettwnsfinilqivwhtpvkyfsisnvkLQG 288
Cdd:PLN00113 196 ASNQLVGQIPRELGQM--------------------KSLKWIYLGYNN-----------------------------LSG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 289 QLAFRMfnysdtslkalsihqvvtdvfsfpqsyiysifanmniqnftmsgthmvhmlcpSQVSPFLHVDFTDNLLTDMVF 368
Cdd:PLN00113 227 EIPYEI-----------------------------------------------------GGLTSLNHLDLVYNNLTGPIP 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 369 KDCRNLVRLKTLSLQKNQLKNleNIILTSAKMTSLQKLDISQNSLrysDGGIP--CAWTQSLLVLNLSSNMLTGSVFRCL 446
Cdd:PLN00113 254 SSLGNLKNLQYLFLYQNKLSG--PIPPSIFSLQKLISLDLSDNSL---SGEIPelVIQLQNLEILHLFSNNFTGKIPVAL 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 447 P--PKVKVLDLHNNRIM-SIPKDVTHLQALQELNVASNSLT-DLP-GCGAFSSLSVLVIDHNSVSHPSEDFFQSCQNIRS 521
Cdd:PLN00113 329 TslPRLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTgEIPeGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRR 408
|
490 500
....*....|....*....|
gi 1720413011 522 LTAGNNPFqcTCEL-RDFVK 540
Cdd:PLN00113 409 VRLQDNSF--SGELpSEFTK 426
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
370-497 |
7.75e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 42.88 E-value: 7.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 370 DCRNLVRLKTLSLQKNQLKNleNIILTSAKMTSLQKLDISQNSLrysDGGIPCAWTQ--SLLVLNLSSNMLTGSVfrclP 447
Cdd:PLN03150 437 DISKLRHLQSINLSGNSIRG--NIPPSLGSITSLEVLDLSYNSF---NGSIPESLGQltSLRILNLNGNSLSGRV----P 507
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1720413011 448 PKVKVLDLHNNRimsipkdvthlqalqeLNVASNS-LTDLPG---CGAFSSLSV 497
Cdd:PLN03150 508 AALGGRLLHRAS----------------FNFTDNAgLCGIPGlraCGPHLSVGA 545
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
33-163 |
1.32e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 41.57 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 33 KRPNANLTRVPKDLPLQTTTLDLSQNNISELQTSDILSL----SKLRVLIMSYN------------------RLQYLNIS 90
Cdd:cd00116 122 DRGLRLLAKGLKDLPPALEKLVLGRNRLEGASCEALAKAlranRDLKELNLANNgigdagiralaeglkancNLEVLDLN 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 91 --------------VFKFNTELEYLDLSHN--------ELKVILCHPTVSLKHLDLSFN---AFDALPICKEFGNMSQLQ 145
Cdd:cd00116 202 nngltdegasalaeTLASLKSLEVLNLGDNnltdagaaALASALLSPNISLLTLSLSCNditDDGAKDLAEVLAEKESLL 281
|
170
....*....|....*...
gi 1720413011 146 FLGLSGSRVQSSSVQLIA 163
Cdd:cd00116 282 ELDLRGNKFGEEGAQLLA 299
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
68-136 |
2.03e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.54 E-value: 2.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720413011 68 ILSLSK-LRVLIMSYNRLQylNISVFKFNTELEYLDLSHNELKVI--LCHP---TVSLKHLDLSFNafdalPICK 136
Cdd:cd21340 115 LAALSNsLRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISDLeeLLDLlssWPSLRELDLTGN-----PVCK 182
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
355-522 |
8.86e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 39.39 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 355 HVDFTDNLLTD----MVFKDCRNLVRLKTLSLQKNQL--KNLENIILTSAKMTSLQKLDISQNSLRySDGGIPCA----W 424
Cdd:COG5238 240 TLDLSNNQIGDegviALAEALKNNTTVETLYLSGNQIgaEGAIALAKALQGNTTLTSLDLSVNRIG-DEGAIALAeglqG 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 425 TQSLLVLNLSSNMLTGSVFRCLP------PKVKVLDLHNNRI-----MSIPKDVTHLQALQELNVASNSLTDLpgcGAFS 493
Cdd:COG5238 319 NKTLHTLNLAYNGIGAQGAIALAkalqenTTLHSLDLSDNQIgdegaIALAKYLEGNTTLRELNLGKNNIGKQ---GAEA 395
|
170 180 190
....*....|....*....|....*....|....*...
gi 1720413011 494 --------SLSVLVIDHNSVSHPSED-FFQSCQNIRSL 522
Cdd:COG5238 396 lidalqtnRLHTLILDGNLIGAEAQQrLEQLLERIKSV 433
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
400-506 |
9.77e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 39.45 E-value: 9.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720413011 400 MTSLQKLDISQNSLRysdGGIPCAW-TQSLLVLNLSSNMLTGSVFRCLP--PKVKVLDLHNNRIMS-IPKDVTHLQALQE 475
Cdd:PLN00113 451 MPSLQMLSLARNKFF---GGLPDSFgSKRLENLDLSRNQFSGAVPRKLGslSELMQLKLSENKLSGeIPDELSSCKKLVS 527
|
90 100 110
....*....|....*....|....*....|...
gi 1720413011 476 LNVASNSLT-DLP-GCGAFSSLSVLVIDHNSVS 506
Cdd:PLN00113 528 LDLSHNQLSgQIPaSFSEMPVLSQLDLSQNQLS 560
|
|
| |
