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Conserved domains on  [gi|1753159737|ref|XP_030876003|]
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ubiquitin thioesterase ZRANB1 isoform X1 [Leptonychotes weddellii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AnkUBD pfam18418
Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known ...
 272-367 2.58e-63

Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known as Ubiquitin thioesterase ZRANB1) (EC:3.4.19.12). In TRABID, the first ankyrin repeat spans residues 260-290 and is connected to the second repeat residues 313-340 by a long linker that packs against what would correspond to the concave surface in an extended ankyrin-repeat structure. Ankyrin-repeat domains mediate protein interactions through a variety of surfaces. The ankyrin domain of TRABID interacts with ubiquitin, hence it is referred to as the ankyrin ubiquitin-binding domain, or AnkUBD.


:

Pssm-ID: 408216  Cd Length: 96  Bit Score: 199.10  E-value: 2.58e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753159737 272 EVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQ 351
Cdd:pfam18418   1 EVDFKKLKQIKNRMKKTDWLFLNACVGPIEGDLAAIEAFKLSGGDIAGLLDADEVRLLNRPPAFDVGYTLVHLAIRFQRQ 80

                          90
                  ....*....|....*.
gi 1753159737 352 DMLAILLTEVSQQAAK 367
Cdd:pfam18418  81 DMLAILLTEVSQHAAK 96
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 178-201 9.49e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


:

Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 39.22  E-value: 9.49e-05
                           10        20
                   ....*....|....*....|....
gi 1753159737  178 HWTCSICTYENWAKAKKCVVCDHP 201
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 112-133 1.30e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


:

Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 36.14  E-value: 1.30e-03
                           10        20
                   ....*....|....*....|..
gi 1753159737  112 NKWSCHMCTYLNWPRAIRCTQC 133
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFAC 22
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 33-55 3.31e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


:

Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 34.99  E-value: 3.31e-03
                           10        20
                   ....*....|....*....|...
gi 1753159737   33 KWACEYCTYENWPSAIKCTMCRA 55
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGA 24
 
Name Accession Description Interval E-value
AnkUBD pfam18418
Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known ...
 272-367 2.58e-63

Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known as Ubiquitin thioesterase ZRANB1) (EC:3.4.19.12). In TRABID, the first ankyrin repeat spans residues 260-290 and is connected to the second repeat residues 313-340 by a long linker that packs against what would correspond to the concave surface in an extended ankyrin-repeat structure. Ankyrin-repeat domains mediate protein interactions through a variety of surfaces. The ankyrin domain of TRABID interacts with ubiquitin, hence it is referred to as the ankyrin ubiquitin-binding domain, or AnkUBD.


Pssm-ID: 408216  Cd Length: 96  Bit Score: 199.10  E-value: 2.58e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753159737 272 EVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQ 351
Cdd:pfam18418   1 EVDFKKLKQIKNRMKKTDWLFLNACVGPIEGDLAAIEAFKLSGGDIAGLLDADEVRLLNRPPAFDVGYTLVHLAIRFQRQ 80

                          90
                  ....*....|....*.
gi 1753159737 352 DMLAILLTEVSQQAAK 367
Cdd:pfam18418  81 DMLAILLTEVSQHAAK 96
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 178-201 9.49e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 39.22  E-value: 9.49e-05
                           10        20
                   ....*....|....*....|....
gi 1753159737  178 HWTCSICTYENWAKAKKCVVCDHP 201
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGAP 25
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
175-204 3.73e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 37.72  E-value: 3.73e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1753159737 175 RTQHWTCSICTYENWAKAKKCVVCDHPRPN 204
Cdd:pfam00641   1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 112-133 1.30e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 36.14  E-value: 1.30e-03
                           10        20
                   ....*....|....*....|..
gi 1753159737  112 NKWSCHMCTYLNWPRAIRCTQC 133
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFAC 22
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 33-55 3.31e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 34.99  E-value: 3.31e-03
                           10        20
                   ....*....|....*....|...
gi 1753159737   33 KWACEYCTYENWPSAIKCTMCRA 55
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGA 24
 
Name Accession Description Interval E-value
AnkUBD pfam18418
Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known ...
 272-367 2.58e-63

Ankyrin ubiquitin-binding domain; This is an Ankyrin repeat domain found in TRABID (also known as Ubiquitin thioesterase ZRANB1) (EC:3.4.19.12). In TRABID, the first ankyrin repeat spans residues 260-290 and is connected to the second repeat residues 313-340 by a long linker that packs against what would correspond to the concave surface in an extended ankyrin-repeat structure. Ankyrin-repeat domains mediate protein interactions through a variety of surfaces. The ankyrin domain of TRABID interacts with ubiquitin, hence it is referred to as the ankyrin ubiquitin-binding domain, or AnkUBD.


Pssm-ID: 408216  Cd Length: 96  Bit Score: 199.10  E-value: 2.58e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1753159737 272 EVDFKKLKQIKNRMKKTDWLFLNACVGVVEGDLAAIEAYKSSGGDIARQLTADEVRLLNRPSAFDVGYTLVHLAIRFQRQ 351
Cdd:pfam18418   1 EVDFKKLKQIKNRMKKTDWLFLNACVGPIEGDLAAIEAFKLSGGDIAGLLDADEVRLLNRPPAFDVGYTLVHLAIRFQRQ 80

                          90
                  ....*....|....*.
gi 1753159737 352 DMLAILLTEVSQQAAK 367
Cdd:pfam18418  81 DMLAILLTEVSQHAAK 96
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 178-201 9.49e-05

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 39.22  E-value: 9.49e-05
                           10        20
                   ....*....|....*....|....
gi 1753159737  178 HWTCSICTYENWAKAKKCVVCDHP 201
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGAP 25
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
175-204 3.73e-04

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 37.72  E-value: 3.73e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1753159737 175 RTQHWTCSICTYENWAKAKKCVVCDHPRPN 204
Cdd:pfam00641   1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 112-133 1.30e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 36.14  E-value: 1.30e-03
                           10        20
                   ....*....|....*....|..
gi 1753159737  112 NKWSCHMCTYLNWPRAIRCTQC 133
Cdd:smart00547   1 GDWECPACTFLNFASRSKCFAC 22
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 33-55 3.31e-03

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 34.99  E-value: 3.31e-03
                           10        20
                   ....*....|....*....|...
gi 1753159737   33 KWACEYCTYENWPSAIKCTMCRA 55
Cdd:smart00547   2 DWECPACTFLNFASRSKCFACGA 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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