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Conserved domains on  [gi|1907168098|ref|XP_036021550|]
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mucin-3A isoform X4 [Mus musculus]

Protein Classification

SEA domain-containing protein( domain architecture ID 10475853)

SEA (found in Sea urchin sperm protein, Enterokinase, Agrin) domain-containing protein similar to vertebrate interphotoreceptor matrix proteoglycan 1 and human membrane mucins (mucin-12, -16 and -17)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 8-90 1.51e-10

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


:

Pssm-ID: 460188  Cd Length: 100  Bit Score: 57.25  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907168098   8 EFSPDLEDNTSKAYKDFSSAFQHQMQKIFQAV---QGFQGVEILSLRR--GSIVVDYQVLLRLAFSPQLKSDFEKVKTVL 82
Cdd:pfam01390  13 QYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLRPdgGSVVVDVVLVFRFPSTEPALDREKLIEEIL 92


                  ....*...
gi 1907168098  83 KEELQSAS 90
Cdd:pfam01390  93 RQTLNNTT 100
 
Name Accession Description Interval E-value
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 8-90 1.51e-10

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 57.25  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907168098   8 EFSPDLEDNTSKAYKDFSSAFQHQMQKIFQAV---QGFQGVEILSLRR--GSIVVDYQVLLRLAFSPQLKSDFEKVKTVL 82
Cdd:pfam01390  13 QYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLRPdgGSVVVDVVLVFRFPSTEPALDREKLIEEIL 92


                  ....*...
gi 1907168098  83 KEELQSAS 90
Cdd:pfam01390  93 RQTLNNTT 100
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 3-90 3.94e-10

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 56.65  E-value: 3.94e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907168098    3 VSVEQE---FSPDLEDNTSKAYKDFSSAFQHQMQKIFQA---VQGFQGVEILSLRRGSIVVDYQVLLRlaFSPQLKSDFE 76
Cdd:smart00200  12 LSVEGEnlqYSPSLEDPSSEEYQELVRDVEKLLEQIYGKtdlKPDFVGTEVIEFRNGSVVVDLGLLFN--EGVTNGQDVE 89

                           90
                   ....*....|....
gi 1907168098   77 KVKTVLKEELQSAS 90
Cdd:smart00200  90 EDLLQVIKQAAYSL 103
 
Name Accession Description Interval E-value
SEA pfam01390
SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed ...
 8-90 1.51e-10

SEA domain; Domain found in Sea urchin sperm protein, Enterokinase, Agrin (SEA). Proposed function of regulating or binding carbohydrate side chains. Recently a proteolytic activity has been shown for a SEA domain.


Pssm-ID: 460188  Cd Length: 100  Bit Score: 57.25  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907168098   8 EFSPDLEDNTSKAYKDFSSAFQHQMQKIFQAV---QGFQGVEILSLRR--GSIVVDYQVLLRLAFSPQLKSDFEKVKTVL 82
Cdd:pfam01390  13 QYTPDLGNPSSQEFKSLSRRIESLLNELFRNSslrKQYIKSHVLRLRPdgGSVVVDVVLVFRFPSTEPALDREKLIEEIL 92


                  ....*...
gi 1907168098  83 KEELQSAS 90
Cdd:pfam01390  93 RQTLNNTT 100
SEA smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating ...
 3-90 3.94e-10

Domain found in sea urchin sperm protein, enterokinase, agrin; Proposed function of regulating or binding carbohydrate sidechains.


Pssm-ID: 214554  Cd Length: 121  Bit Score: 56.65  E-value: 3.94e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907168098    3 VSVEQE---FSPDLEDNTSKAYKDFSSAFQHQMQKIFQA---VQGFQGVEILSLRRGSIVVDYQVLLRlaFSPQLKSDFE 76
Cdd:smart00200  12 LSVEGEnlqYSPSLEDPSSEEYQELVRDVEKLLEQIYGKtdlKPDFVGTEVIEFRNGSVVVDLGLLFN--EGVTNGQDVE 89

                           90
                   ....*....|....
gi 1907168098   77 KVKTVLKEELQSAS 90
Cdd:smart00200  90 EDLLQVIKQAAYSL 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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