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Conserved domains on  [gi|1958802997|ref|XP_038939750|]
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kelch domain-containing protein 3 isoform X1 [Rattus norvegicus]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 11459646)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 9.79e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 126.81  E-value: 9.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055    13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055    78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055   151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802997 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055   208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 9.79e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 126.81  E-value: 9.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055    13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055    78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055   151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802997 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055   208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
PLN02153 PLN02153
epithiospecifier protein
 74-318 6.38e-16

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 78.10  E-value: 6.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  74 PYMRYGHSTVLIDDTVFLWGGRNDTEGACNV-LYAFDVNTHKWSTPRVSGTVPGARD-GHSACVLGKIMYIFGGYEQLAD 151
Cdd:PLN02153   20 PGPRCSHGIAVVGDKLYSFGGELKPNEHIDKdLYVFDFNTHTWSIAPANGDVPRISClGVRMVAVGTKLYIFGGRDEKRE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 152 cfSNDIHKLDTSTMTWTLVC---TKGNPARwRDFHSATMLGNHMYVFGGRADrfGPFHSNNEIYcNRIRVFDTRTEAWLD 228
Cdd:PLN02153  100 --FSDFYSYDTVKNEWTFLTkldEEGGPEA-RTFHSMASDENHVYVFGGVSK--GGLMKTPERF-RTIEAYNIADGKWVQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 229 CPHTPVLPEGRRSHSAFGYNGELYIFGGY------NARLNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGDK 302
Cdd:PLN02153  174 LPDPGENFEKRGGAGFAVVQGKIWVVYGFatsilpGGKSDYESNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKY 253

                         250
                  ....*....|....*..
gi 1958802997 303 IVLFGGTS-PSPEEGLG 318
Cdd:PLN02153  254 IIIFGGEVwPDLKGHLG 270
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 128-171 2.94e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 43.86  E-value: 2.94e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958802997 128 RDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVC 171
Cdd:pfam07646   2 RYPHASSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWTEVP 45
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 9.79e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 126.81  E-value: 9.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055    13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055    78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055   151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802997 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055   208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
11-260 8.53e-33

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 124.11  E-value: 8.53e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  11 GPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQiDVHIFNAVSLRWTKLPPVrpavrgqapvvPYMRYGHSTVLIDDTVF 90
Cdd:COG3055    58 GPPRHHAAAVAQDGKLYVFGGFTGANPSSTPLN-DVYVYDPATNTWTKLAPM-----------PTPRGGATALLLDGKIY 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  91 LWGGRNDtEGACNVLYAFDVNTHKWSTPrvsGTVPGARDGHSACVL--GKImYIFGGYEQladcfsndihklDTSTMTWT 168
Cdd:COG3055   126 VVGGWDD-GGNVAWVEVYDPATGTWTQL---APLPTPRDHLAAAVLpdGKI-LVIGGRNG------------SGFSNTWT 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 169 lvcTKGNPARWRDFHSATMLGNHMYVFGGRadrfGPFHSNNEIYcnrirvfDTRTEAWLdcpHTPVLPEGRRSHSAFGYN 248
Cdd:COG3055   189 ---TLAPLPTARAGHAAAVLGGKILVFGGE----SGFSDEVEAY-------DPATNTWT---ALGELPTPRHGHAAVLTD 251

                         250
                  ....*....|..
gi 1958802997 249 GELYIFGGYNAR 260
Cdd:COG3055   252 GKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
56-310 2.79e-24

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 101.00  E-value: 2.79e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  56 WTKLPPVrPAVRGQApvvpymryghSTVLIDDTVFLWGGrNDTEGACNVLYAFDVNTHKWSTprvSGTVPGARDGHSACV 135
Cdd:COG3055     3 WSSLPDL-PTPRSEA----------AAALLDGKVYVAGG-LSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAV 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 136 L--GKImYIFGGYEQLAD--CFSNDIHKLDTSTMTWTlvcTKGNPARWRDFHSATMLGNHMYVFGGRadrfgpfhsNNEI 211
Cdd:COG3055    68 AqdGKL-YVFGGFTGANPssTPLNDVYVYDPATNTWT---KLAPMPTPRGGATALLLDGKIYVVGGW---------DDGG 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 212 YCNRIRVFDTRTEAWLDcphTPVLPEGRRSHSA-FGYNGELYIFGGYNarlnrhfhdlwkFNPGSFTWKKIEPKgkgPCP 290
Cdd:COG3055   135 NVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAaVLPDGKILVIGGRN------------GSGFSNTWTTLAPL---PTA 196

                         250       260
                  ....*....|....*....|
gi 1958802997 291 RRRQCCCIVGDKIVLFGGTS 310
Cdd:COG3055   197 RAGHAAAVLGGKILVFGGES 216
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
3-197 6.85e-17

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 80.20  E-value: 6.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997   3 RWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYEtlrqiDVHIFNAVSLRWTKLPPvrpavrgqapvVPYMRYGHS- 81
Cdd:COG3055   101 TWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVA-----WVEVYDPATGTWTQLAP-----------LPTPRDHLAa 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  82 TVLIDDTVFLWGGRNDTegacnvlyafdVNTHKWSTPrvsGTVPGARDGHSACVLGKIMYIFGGYEQladcFSNDIHKLD 161
Cdd:COG3055   165 AVLPDGKILVIGGRNGS-----------GFSNTWTTL---APLPTARAGHAAAVLGGKILVFGGESG----FSDEVEAYD 226

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1958802997 162 TSTMTWTLVCTKGNParwRDFHSATMLGNHMYVFGG 197
Cdd:COG3055   227 PATNTWTALGELPTP---RHGHAAVLTDGKVYVIGG 259
PLN02153 PLN02153
epithiospecifier protein
 74-318 6.38e-16

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 78.10  E-value: 6.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  74 PYMRYGHSTVLIDDTVFLWGGRNDTEGACNV-LYAFDVNTHKWSTPRVSGTVPGARD-GHSACVLGKIMYIFGGYEQLAD 151
Cdd:PLN02153   20 PGPRCSHGIAVVGDKLYSFGGELKPNEHIDKdLYVFDFNTHTWSIAPANGDVPRISClGVRMVAVGTKLYIFGGRDEKRE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 152 cfSNDIHKLDTSTMTWTLVC---TKGNPARwRDFHSATMLGNHMYVFGGRADrfGPFHSNNEIYcNRIRVFDTRTEAWLD 228
Cdd:PLN02153  100 --FSDFYSYDTVKNEWTFLTkldEEGGPEA-RTFHSMASDENHVYVFGGVSK--GGLMKTPERF-RTIEAYNIADGKWVQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 229 CPHTPVLPEGRRSHSAFGYNGELYIFGGY------NARLNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGDK 302
Cdd:PLN02153  174 LPDPGENFEKRGGAGFAVVQGKIWVVYGFatsilpGGKSDYESNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKY 253

                         250
                  ....*....|....*..
gi 1958802997 303 IVLFGGTS-PSPEEGLG 318
Cdd:PLN02153  254 IIIFGGEVwPDLKGHLG 270
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
180-322 1.28e-15

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 76.35  E-value: 1.28e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 180 RDFHSATMLGNHMYVFGGradrfgpfhSNNEIYCNRIRVFDTRTEAWLdcpHTPVLPEGRRSHSA-FGYNGELYIFGGYN 258
Cdd:COG3055    13 RSEAAAALLDGKVYVAGG---------LSGGSASNSFEVYDPATNTWS---ELAPLPGPPRHHAAaVAQDGKLYVFGGFT 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958802997 259 ARLN--RHFHDLWKFNPGSFTWKKIEPkgkGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFD 322
Cdd:COG3055    81 GANPssTPLNDVYVYDPATNTWTKLAP---MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYD 143
PLN02193 PLN02193
nitrile-specifier protein
 61-322 1.97e-15

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 77.69  E-value: 1.97e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  61 PVRPAVRGQAPVV------PYMRYGHSTVLIDDTVFLWGGR-NDTEGACNVLYAFDVNTHKWSTPRVSGTVPgardgHSA 133
Cdd:PLN02193  144 PSTPKLLGKWIKVeqkgegPGLRCSHGIAQVGNKIYSFGGEfTPNQPIDKHLYVFDLETRTWSISPATGDVP-----HLS 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 134 CV------LGKIMYIFGGYEqlADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFHSATMLGNHMYVFGGRADRfgpfhs 207
Cdd:PLN02193  219 CLgvrmvsIGSTLYVFGGRD--ASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSAT------ 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 208 nneiycNRIRVFDTRT---EAWLDCPhTPVlpegrRSHSAFG------YNGELYIFGGYNARlnrHFHDLWKFNPGSFTW 278
Cdd:PLN02193  291 ------ARLKTLDSYNivdKKWFHCS-TPG-----DSFSIRGgaglevVQGKVWVVYGFNGC---EVDDVHYYDPVQDKW 355

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1958802997 279 KKIEPKGKGPCPRRRQCCCIVGDKIVLFGG---TSPSPEEGLGDEFD 322
Cdd:PLN02193  356 TQVETFGVRPSERSVFASAAVGKHIVIFGGeiaMDPLAHVGPGQLTD 402
PLN02153 PLN02153
epithiospecifier protein
 9-198 4.05e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 70.02  E-value: 4.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997   9 EGGPR-RVNHAAVAVGHRVYSFGGYCSGEDYETLRQI-DVHIFNAVSLRWTKLPPvrPA-------------VRGQAPVV 73
Cdd:PLN02153  122 EGGPEaRTFHSMASDENHVYVFGGVSKGGLMKTPERFrTIEAYNIADGKWVQLPD--PGenfekrggagfavVQGKIWVV 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  74 pymrYGHSTVLIDdtvflwGGRNDTEGacNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGGyEQLAD-- 151
Cdd:PLN02153  200 ----YGFATSILP------GGKSDYES--NAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG-EVWPDlk 266

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958802997 152 ------CFSNDIHKLDTSTMTWTLVCTKGNPAR---WRDFHSATMLG-NHMYVFGGR 198
Cdd:PLN02153  267 ghlgpgTLSNEGYALDTETLVWEKLGECGEPAMprgWTAYTTATVYGkNGLLMHGGK 323
PLN02193 PLN02193
nitrile-specifier protein
 167-330 1.11e-11

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 66.13  E-value: 1.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 167 WTLVCTKGNPARWRDFHSATMLGNHMYVFGGRadrFGPfhsnNEIYCNRIRVFDTRTEAWLDCPHTPVLPE----GRRSH 242
Cdd:PLN02193  153 WIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGE---FTP----NQPIDKHLYVFDLETRTWSISPATGDVPHlsclGVRMV 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 243 SAfgyNGELYIFGGYNArlNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFD 322
Cdd:PLN02193  226 SI---GSTLYVFGGRDA--SRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYN 300


                  ....*...
gi 1958802997 323 LIDHSDLH 330
Cdd:PLN02193  301 IVDKKWFH 308
PLN02193 PLN02193
nitrile-specifier protein
 9-197 2.26e-11

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 64.98  E-value: 2.26e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997   9 EGGPRRVNHAAVAVGHRVYSFGGycsgeDYETLRQIDVH--IFNAVSLRWTklppVRPAVrGQAPVVPYMryGHSTVLID 86
Cdd:PLN02193  161 EGPGLRCSHGIAQVGNKIYSFGG-----EFTPNQPIDKHlyVFDLETRTWS----ISPAT-GDVPHLSCL--GVRMVSIG 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  87 DTVFLWGGRnDTEGACNVLYAFDVNTHKWS--TPRVSGTVPgaRDGHSACVLGKIMYIFGGYEQLA-------------- 150
Cdd:PLN02193  229 STLYVFGGR-DASRQYNGFYSFDTTTNEWKllTPVEEGPTP--RSFHSMAADEENVYVFGGVSATArlktldsynivdkk 305

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 151 ---------------------------------DCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFHSATMLGNHMYVFGG 197
Cdd:PLN02193  306 wfhcstpgdsfsirggaglevvqgkvwvvygfnGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG 385
PHA03098 PHA03098
kelch-like protein; Provisional
 77-308 4.51e-11

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 64.40  E-value: 4.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  77 RYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWstprvsGTVP---GARDGHSACVLGKIMYIFGGYEQlaDCF 153
Cdd:PHA03098  285 VYCFGSVVLNNVIYFIGGMNKNNLSVNSVVSYDTKTKSW------NKVPeliYPRKNPGVTVFNNRIYVIGGIYN--SIS 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 154 SNDIHKLDTSTMTWTLVCTKGNParwRDFHSATMLGNHMYVFGGRadrfgpfhSNNEIYCNRIRVFDTRTEAWLDCPHTP 233
Cdd:PHA03098  357 LNTVESWKPGESKWREEPPLIFP---RYNPCVVNVNNLIYVIGGI--------SKNDELLKTVECFSLNTNKWSKGSPLP 425

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958802997 234 VLPEGrrsHSAFGYNGELYIFGGYNARLNRH-FHDLWKFNPGSFTWKKIEPKGKgpcPRRRQCCCIVGDKIVLFGG 308
Cdd:PHA03098  426 ISHYG---GCAIYHDGKIYVIGGISYIDNIKvYNIVESYNPVTNKWTELSSLNF---PRINASLCIFNNKIYVVGG 495
PLN02153 PLN02153
epithiospecifier protein
 122-256 5.82e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 63.47  E-value: 5.82e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 122 GTVPGARDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFH-SATMLGNHMYVFGGRAD 200
Cdd:PLN02153   17 GKGPGPRCSHGIAVVGDKLYSFGGELKPNEHIDKDLYVFDFNTHTWSIAPANGDVPRISCLGvRMVAVGTKLYIFGGRDE 96

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 201 R--FGPFHSnneiycnrirvFDTRTEAWLDCPHTPVL--PEGRRSHSAFGYNGELYIFGG 256
Cdd:PLN02153   97 KreFSDFYS-----------YDTVKNEWTFLTKLDEEggPEARTFHSMASDENHVYVFGG 145
PHA03098 PHA03098
kelch-like protein; Provisional
 14-235 1.38e-09

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 59.78  E-value: 1.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDYetlrqIDVHIFNAVSLRWTKLPPVRpavrgqapvvpYMRYGHSTVLIDDTVFLWG 93
Cdd:PHA03098  333 RKNPGVTVFNNRIYVIGGIYNSISL-----NTVESWKPGESKWREEPPLI-----------FPRYNPCVVNVNNLIYVIG 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  94 GRNDTEGACNVLYAFDVNTHKWSTPRVSgtvPGARDGHSACVLGKIMYIFGG--YEQLADCFSNdIHKLDTSTMTWT--- 168
Cdd:PHA03098  397 GISKNDELLKTVECFSLNTNKWSKGSPL---PISHYGGCAIYHDGKIYVIGGisYIDNIKVYNI-VESYNPVTNKWTels 472

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958802997 169 -LVCTKGNParwrdfhSATMLGNHMYVFGGradrfgpfhSNNEIYCNRIRVFDTRTEAW-LDCPHTPVL 235
Cdd:PHA03098  473 sLNFPRINA-------SLCIFNNKIYVVGG---------DKYEYYINEIEVYDDKTNTWtLFCKFPKVI 525
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 128-171 2.94e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 43.86  E-value: 2.94e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958802997 128 RDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVC 171
Cdd:pfam07646   2 RYPHASSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWTEVP 45
Kelch_3 pfam13415
Galactose oxidase, central domain;
86-136 5.45e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 43.05  E-value: 5.45e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958802997  86 DDTVFLWGGRNDTEGAC-NVLYAFDVNTHKWSTPrvsGTVPGARDGHSACVL 136
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRlNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
PLN02772 PLN02772
guanylate kinase
 81-145 1.01e-05

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 47.14  E-value: 1.01e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958802997  81 STVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVL--GKIMYIFGG 145
Cdd:PLN02772   29 TSVTIGDKTYVIGGNHEGNTLSIGVQILDKITNNWVSPIVLGTGPKPCKGYSAVVLnkDRILVIKKG 95
Kelch_4 pfam13418
Galactose oxidase, central domain;
77-117 1.89e-05

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 41.44  E-value: 1.89e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1958802997  77 RYGHSTVLI-DDTVFLWGGRNDTEGACNVLYAFDVNTHKWST 117
Cdd:pfam13418   2 RAYHTSTSIpDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTR 43
Kelch_6 pfam13964
Kelch motif;
14-61 2.53e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 41.17  E-value: 2.53e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDYetlrQIDVHIFNAVSLRWTKLPP 61
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPA----LNKLEVYNPLTKSWEELPP 45
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 236-276 2.88e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 41.01  E-value: 2.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1958802997 236 PEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPGSF 276
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPTF 41
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 125-164 3.11e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 40.63  E-value: 3.11e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958802997 125 PGARDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTST 164
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPT 40
PLN02193 PLN02193
nitrile-specifier protein
 8-203 3.51e-05

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 45.72  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997   8 LEGGPR-RVNHAAVAVGHRVYSFGGYCSGEDYETLRQidvhiFNAVSLRW--TKLPPVRPAVRGQA--PVVP---YMRYG 79
Cdd:PLN02193  262 VEEGPTpRSFHSMAADEENVYVFGGVSATARLKTLDS-----YNIVDKKWfhCSTPGDSFSIRGGAglEVVQgkvWVVYG 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  80 HSTVLIDDtvflwggrndtegacnvLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGG---YEQLADC---- 152
Cdd:PLN02193  337 FNGCEVDD-----------------VHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGGeiaMDPLAHVgpgq 399

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958802997 153 FSNDIHKLDTSTMTW----TLVCTKGNPAR--WRDFHSATMLGNH-MYVFGGRA---DRFG 203
Cdd:PLN02193  400 LTDGTFALDTETLQWerldKFGEEEETPSSrgWTASTTGTIDGKKgLVMHGGKAptnDRFD 460
PRK14131 PRK14131
N-acetylneuraminate epimerase;
155-268 5.60e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 45.01  E-value: 5.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997 155 NDIHKLDTSTMT--WTLVCTKGNPARwrDFHSATMLGNHMYVFGG--RADRFGPFHSNNEIYcnrirVFDTRTEAWLDCP 230
Cdd:PRK14131   50 TSWYKLDLNAPSkgWTKIAAFPGGPR--EQAVAAFIDGKLYVFGGigKTNSEGSPQVFDDVY-----KYDPKTNSWQKLD 122

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1958802997 231 -HTPVlpeGRRSHSAFGYNG-ELYIFGGYNARL-NRHFHDL 268
Cdd:PRK14131  123 tRSPV---GLAGHVAVSLHNgKAYITGGVNKNIfDGYFEDL 160
Kelch_4 pfam13418
Galactose oxidase, central domain;
13-62 7.69e-05

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 39.90  E-value: 7.69e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958802997  13 RRVNHAAVAVG-HRVYSFGGYcsGEDYETLrqIDVHIFNAVSLRWTKLPPV 62
Cdd:pfam13418   1 PRAYHTSTSIPdDTIYLFGGE--GEDGTLL--SDLWVFDLSTNEWTRLGSL 47
Kelch_3 pfam13415
Galactose oxidase, central domain;
248-299 1.31e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 39.20  E-value: 1.31e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958802997 248 NGELYIFGGYNARLNRHFHDLWKFNPGSFTWKKIepkgkGPCPRRRQCCCIV 299
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTWTQI-----GDLPPPRSGHSAT 47
Kelch_6 pfam13964
Kelch motif;
76-117 1.74e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.86  E-value: 1.74e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1958802997  76 MRYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWST 117
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEE 42
Kelch_6 pfam13964
Kelch motif;
239-283 2.42e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.47  E-value: 2.42e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1958802997 239 RRSHSAFGYNGELYIFGGYNARLNRHFhDLWKFNPGSFTWKKIEP 283
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALN-KLEVYNPLTKSWEELPP 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 239-283 3.71e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.98  E-value: 3.71e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1958802997 239 RRSHSAFGYNGELYIFGGYNArlNRHFHDLWKFNPGSFTWKKIEP 283
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDG--NQSLNSVEVYDPETNTWSKLPS 44
Kelch_3 pfam13415
Galactose oxidase, central domain;
137-186 4.68e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 37.65  E-value: 4.68e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1958802997 137 GKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTlVCTKGNPArwRDFHSAT 186
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTWT-QIGDLPPP--RSGHSAT 47
Kelch_4 pfam13418
Galactose oxidase, central domain;
238-284 5.50e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.59  E-value: 5.50e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958802997 238 GRRSHSAFG-YNGELYIFGGYNA---RLNrhfhDLWKFNPGSFTWKKIEPK 284
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEGEdgtLLS----DLWVFDLSTNEWTRLGSL 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 13-61 6.31e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.21  E-value: 6.31e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1958802997  13 RRVNHAAVAVGHRVYSFGGYCSGEdyetlRQIDVHIFNAVSLRWTKLPP 61
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-----SLNSVEVYDPETNTWSKLPS 44
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 127-170 7.10e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.21  E-value: 7.10e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958802997 127 ARDGHSACVLGKIMYIFGGYEqlADCFSNDIHKLDTSTMTWTLV 170
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD--GNQSLNSVEVYDPETNTWSKL 42
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 13-62 7.89e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 36.93  E-value: 7.89e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1958802997  13 RRVNHAAVAVGHRVYSFGGYCSGEDyetLRQIDVHIFNAVSLRWTKLPPV 62
Cdd:pfam07646   1 PRYPHASSVPGGKLYVVGGSDGLGD---LSSSDVLVYDPETNVWTEVPRL 47
Kelch_6 pfam13964
Kelch motif;
179-230 9.62e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 9.62e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958802997 179 WRDFHSATMLGNHMYVFGGRADRFGPFhsnneiycNRIRVFDTRTEAWLDCP 230
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPAL--------NKLEVYNPLTKSWEELP 44
PRK14131 PRK14131
N-acetylneuraminate epimerase;
10-96 1.40e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 40.38  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  10 GGPRrvNHA-AVAVGHRVYSFGGycSG-EDYETLRQI--DVHIFNAVSLRWTKLPPVRPavRGQApvvpymryGHSTVLI 85
Cdd:PRK14131   72 GGPR--EQAvAAFIDGKLYVFGG--IGkTNSEGSPQVfdDVYKYDPKTNSWQKLDTRSP--VGLA--------GHVAVSL 137

                          90
                  ....*....|..
gi 1958802997  86 DDT-VFLWGGRN 96
Cdd:PRK14131  138 HNGkAYITGGVN 149
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-110 2.02e-03

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 39.75  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  14 RVNHAAVAVGHRVYSFGGYCSGEDyetlrqiDVHIFNAVSLRWTKLPPVrpavrgqapvvPYMRYGHSTVLIDDTVFLWG 93
Cdd:COG3055   197 RAGHAAAVLGGKILVFGGESGFSD-------EVEAYDPATNTWTALGEL-----------PTPRHGHAAVLTDGKVYVIG 258

                          90
                  ....*....|....*..
gi 1958802997  94 GRNDTEGACNVLYAFDV 110
Cdd:COG3055   259 GETKPGVRTPLVTSAEV 275
PRK14131 PRK14131
N-acetylneuraminate epimerase;
65-197 3.75e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 39.23  E-value: 3.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958802997  65 AVRGQAPVVPY-MRYGHSTvLIDDTVFLWGGrndteGACNVLYAFDVNT--HKWStpRVSGTVPGARDGHSACVLGKIMY 141
Cdd:PRK14131   17 ANAEQLPDLPVpFKNGTGA-IDNNTVYVGLG-----SAGTSWYKLDLNApsKGWT--KIAAFPGGPREQAVAAFIDGKLY 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958802997 142 IFGGYEQLADCFS----NDIHKLDTSTMTWTLVCTKgnPARWRDFHSATML-GNHMYVFGG 197
Cdd:PRK14131   89 VFGGIGKTNSEGSpqvfDDVYKYDPKTNSWQKLDTR--SPVGLAGHVAVSLhNGKAYITGG 147
Kelch_4 pfam13418
Galactose oxidase, central domain;
127-170 4.95e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.90  E-value: 4.95e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1958802997 127 ARDGHSACVLGK-IMYIFGGYeQLADCFSNDIHKLDTSTMTWTLV 170
Cdd:pfam13418   1 PRAYHTSTSIPDdTIYLFGGE-GEDGTLLSDLWVFDLSTNEWTRL 44
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 180-230 5.05e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 34.90  E-value: 5.05e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1958802997 180 RDFHSATMLGNHMYVFGGRadrfgpfhsNNEIYCNRIRVFDTRTEAWLDCP 230
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGF---------DGNQSLNSVEVYDPETNTWSKLP 43
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 76-116 5.85e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 34.51  E-value: 5.85e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1958802997  76 MRYGHSTVLIDDTVFLWGGRNDTEgACNVLYAFDVNTHKWS 116
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-SLNSVEVYDPETNTWS 40
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 74-112 6.91e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 34.08  E-value: 6.91e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1958802997  74 PYMRYGHSTVLIDDTVFLWGGRNDTEGA-CNVLYAFDVNT 112
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQpSDDVYVLSLPT 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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