NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958672921|ref|XP_038946873|]
View 

TRAF3-interacting JNK-activating modulator isoform X3 [Rattus norvegicus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-270 8.53e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 8.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  83 AEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQT 162
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 163 KLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQglpvwnpKLSFDEVKPEG 242
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE-------EELEELAEELL 389

                         170       180
                  ....*....|....*....|....*...
gi 1958672921 243 TGKEKVEELRDQLQKETYQLQAKEKERQ 270
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLE 417
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-270 8.53e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 8.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  83 AEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQT 162
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 163 KLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQglpvwnpKLSFDEVKPEG 242
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE-------EELEELAEELL 389

                         170       180
                  ....*....|....*....|....*...
gi 1958672921 243 TGKEKVEELRDQLQKETYQLQAKEKERQ 270
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLE 417
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 26-195 4.43e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 4.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   26 DKLKGKLRSLENQLYTCLQKHSpwGMKKVLLDMENQRSSYEQK---AKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQ 102
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQIS--ALRKDLARLEAEVEQLEERiaqLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  103 EWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQ 182
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          170
                   ....*....|...
gi 1958672921  183 DQLKKSEEERQAL 195
Cdd:TIGR02168  866 ELIEELESELEAL 878
PRK12704 PRK12704
phosphodiesterase; Provisional
 70-199 1.40e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  70 KASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQ-EWKSQYEALKEDWrtlgdqHRELESQLHVLQSKLQGADSRDSQMSQ 148
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALlEAKEEIHKLRNEF------EKELRERRNELQKLEKRLLQKEENLDR 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958672921 149 ALRLLENEHQELQTK---LESLQGDREQQSSETQDLQDQLKK---------SEEERQALMSRV 199
Cdd:PRK12704  101 KLELLEKREEELEKKekeLEQKQQELEKKEEELEELIEEQLQelerisgltAEEAKEILLEKV 163
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-270 8.53e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 8.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  83 AEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQT 162
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 163 KLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQglpvwnpKLSFDEVKPEG 242
Cdd:COG1196   317 RLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE-------EELEELAEELL 389

                         170       180
                  ....*....|....*....|....*...
gi 1958672921 243 TGKEKVEELRDQLQKETYQLQAKEKERQ 270
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLE 417
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 67-218 1.51e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 1.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  67 QKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQM 146
Cdd:COG1196   242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEEL 321

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958672921 147 SQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEK 218
Cdd:COG1196   322 EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 59-270 4.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 4.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  59 ENQRSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQG 138
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 139 ADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEK 218
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1958672921 219 LLKKDQGLPVWNPKLSFDEVKPEGTGKEKVEELRDQLQKETYQLQAKEKERQ 270
Cdd:COG1196   450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 26-195 4.43e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 4.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   26 DKLKGKLRSLENQLYTCLQKHSpwGMKKVLLDMENQRSSYEQK---AKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQ 102
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQIS--ALRKDLARLEAEVEQLEERiaqLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  103 EWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQ 182
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

                          170
                   ....*....|...
gi 1958672921  183 DQLKKSEEERQAL 195
Cdd:TIGR02168  866 ELIEELESELEAL 878
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
84-265 1.41e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   84 EQQLQRAQLSLAVAE---QKCQEWKSQYEALKEDWRTLGDQ------HRELESQLHVLQSKLQGADSRDSQmsqaLRLLE 154
Cdd:COG4913    616 EAELAELEEELAEAEerlEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDD----LAALE 691

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  155 NEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLqsllqnqslqlreqekllkkdQGLPVWNPKLS 234
Cdd:COG4913    692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA---------------------EDLARLELRAL 750

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1958672921  235 FDEVKPEGTGKEKVEELRDQLQKETYQLQAK 265
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRAR 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 83-224 1.75e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  83 AEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQ- 161
Cdd:COG1196   209 AEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQa 288

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958672921 162 ------TKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQ 224
Cdd:COG1196   289 eeyellAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 62-199 1.77e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 1.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   62 RSSYEQKAKASLQKVLEEkmcAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADS 141
Cdd:TIGR02168  219 KAELRELELALLVLRLEE---LREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958672921  142 RDSQMSQALRLLENEHQELQTKLESLQGDREQQSS---------------------ETQDLQDQLKKSEEERQALMSRV 199
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEELESkldelaeelaeleekleelkeELESLEAELEELEAELEELESRL 374
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 25-270 5.59e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 5.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   25 EDKLKGKLRSLENQLYTCLQKHSPWGMKKVLLDMENQRSSYEQKAKASLQKVLE-EKMCAEQQLQRAQLSLAVAEQKCQE 103
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEqQKQILRERLANLERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  104 WKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQD 183
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEA 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  184 QLKKSEEERQALmsrvqqlqsllqnqslqLREQEKLLKKDQGLPVWNPKLSFDEVKPEGTG-KEKVEELRDQLQKETYQL 262
Cdd:TIGR02168  408 RLERLEDRRERL-----------------QQEIEELLKKLEEAELKELQAELEELEEELEElQEELERLEEALEELREEL 470


                   ....*...
gi 1958672921  263 QAKEKERQ 270
Cdd:TIGR02168  471 EEAEQALD 478
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
71-199 6.54e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 6.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   71 ASLQKVLEEKmcaEQQLQRAQLS---LAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMS 147
Cdd:COG4913    664 ASAEREIAEL---EAELERLDASsddLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAE 740

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958672921  148 QALRllENEHQELQTKLESLQGDrEQQSSETQDLQDQLKKSEEERQALMSRV 199
Cdd:COG4913    741 DLAR--LELRALLEERFAAALGD-AVERELRENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
62-216 3.76e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 3.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   62 RSSYEQKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADS 141
Cdd:COG4913    258 RELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG 337

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958672921  142 RDsqmsqaLRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQ 216
Cdd:COG4913    338 DR------LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEA 406
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 53-223 5.84e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 5.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   53 KVLLDMENQRSSYEQKAKaSLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVL 132
Cdd:TIGR02169  333 KLLAEIEELEREIEEERK-RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  133 QSKLQGADSRDSQMSQALRLLENEHQELQT--------------KLESLQGDREQQSSETQDLQDQLKKSEEERQAL--- 195
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEekedkaleikkqewKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLqre 491

                          170       180
                   ....*....|....*....|....*...
gi 1958672921  196 MSRVQQLQSLLQNQSLQLREQEKLLKKD 223
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKAS 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 67-240 6.44e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.20  E-value: 6.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   67 QKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSR---- 142
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARlerl 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  143 --------DSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEE----RQALMSRVQQLQSLLQNQS 210
Cdd:TIGR02168  413 edrrerlqQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEleeaEQALDAAERELAQLQARLD 492

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1958672921  211 LQLREQEKLLKKDQGLP-VWNPKLSFDEVKP 240
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKaLLKNQSGLSGILG 523
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 83-221 1.06e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.81  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   83 AEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQT 162
Cdd:TIGR02168  682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958672921  163 KLESLQGDREQqssetqdLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLK 221
Cdd:TIGR02168  762 EIEELEERLEE-------AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813
PRK12704 PRK12704
phosphodiesterase; Provisional
 70-199 1.40e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 1.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  70 KASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQ-EWKSQYEALKEDWrtlgdqHRELESQLHVLQSKLQGADSRDSQMSQ 148
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALlEAKEEIHKLRNEF------EKELRERRNELQKLEKRLLQKEENLDR 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958672921 149 ALRLLENEHQELQTK---LESLQGDREQQSSETQDLQDQLKK---------SEEERQALMSRV 199
Cdd:PRK12704  101 KLELLEKREEELEKKekeLEQKQQELEKKEEELEELIEEQLQelerisgltAEEAKEILLEKV 163
PTZ00186 PTZ00186
heat shock 70 kDa precursor protein; Provisional
 57-193 1.61e-03

heat shock 70 kDa precursor protein; Provisional


Pssm-ID: 140213 [Multi-domain]  Cd Length: 657  Bit Score: 40.05  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  57 DMENQRSSYEQKAKASLQK--VLEEKMCAEQQLQraqlslaVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQS 134
Cdd:PTZ00186  531 QIEQMIRDSEQHAEADRVKreLVEVRNNAETQLT-------TAERQLGEWKYVSDAEKENVKTLVAELRKAMENPNVAKD 603

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958672921 135 KLQGADSRdsqMSQAlrLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQ 193
Cdd:PTZ00186  604 DLAAATDK---LQKA--VMECGRTEYQQAAAANSGSSSNSGEQQQQQQQQQQQNSEEKK 657
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 71-273 1.80e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.05  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   71 ASLQKVLEEKmcaEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKLQGADSRDSQMSQAL 150
Cdd:TIGR02169  304 ASLERSIAEK---ERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  151 RLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQLQSLLQNQSLQLREQEKLLKKDQGLPVWN 230
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1958672921  231 PKLSFDEVKPEGTGKEKVEELRDQLQKETYQLQAKEKERQCSQ 273
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 67-224 2.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 2.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  67 QKAKASLQKVLEEKMCAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTLGDQHRELESQLHVLQSKL---------- 136
Cdd:COG4942    37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELaellralyrl 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 137 ---------------QGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQ 201
Cdd:COG4942   117 grqpplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196

                         170       180
                  ....*....|....*....|...
gi 1958672921 202 LQSLLQNQSLQLREQEKLLKKDQ 224
Cdd:COG4942   197 RQKLLARLEKELAELAAELAELQ 219
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
25-187 4.04e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.74  E-value: 4.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   25 EDKLKGKLRSLENQLYTCLQKHSpwGMKKVLLDMENQRSSYEQKAKASLQKVLEEkmcAEQQLQRAQLSLAVAEQKCQEW 104
Cdd:COG4913    297 LEELRAELARLEAELERLEARLD--ALREELDELEAQIRGNGGDRLEQLEREIER---LERELEERERRRARLEALLAAL 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  105 KSQYEALKEDWRtlgDQHRELESQLHVLQSKLQGADSRDSQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQ 184
Cdd:COG4913    372 GLPLPASAEEFA---ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448


                   ...
gi 1958672921  185 LKK 187
Cdd:COG4913    449 LAE 451
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 123-268 5.69e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 38.50  E-value: 5.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  123 RELESQLHVLQSKLQgadsrdsQMSQALRLLENEHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRVQQL 202
Cdd:TIGR02168  680 EELEEKIEELEEKIA-------ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958672921  203 QSLLQNQSLQLREQEKLLKKDQglpvwnPKLSFDEVKPEgTGKEKVEELRDQLQKETYQLQAKEKE 268
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAE------EELAEAEAEIE-ELEAQIEQLKEELKALREALDELRAE 811
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
26-195 5.73e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 38.07  E-value: 5.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921  26 DKLKGKLRSLENQLYTCLQKHSpwgmkkvLLDMENQRSSYEQKAKAslqkvleekmcAEQQLQRAQLSLAVAEQKCQEWK 105
Cdd:COG3206   185 PELRKELEEAEAALEEFRQKNG-------LVDLSEEAKLLLQQLSE-----------LESQLAEARAELAEAEARLAALR 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921 106 SQYEALKEDWRTLGD--QHRELESQLHVLQSKLQGADSR-----------DSQMSQALRLLEnehQELQTKLESLQGDRE 172
Cdd:COG3206   247 AQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARytpnhpdvialRAQIAALRAQLQ---QEAQRILASLEAELE 323

                         170       180
                  ....*....|....*....|...
gi 1958672921 173 QQSSETQDLQDQLKKSEEERQAL 195
Cdd:COG3206   324 ALQAREASLQAQLAQLEARLAEL 346
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
67-199 5.79e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 38.36  E-value: 5.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958672921   67 QKAKASLQKVLEEkmcAEQQLQRAQLSLAVAEQKCQEWKSQYEALKEDWRTL-GDQHRELESQLHVLQSKLQGADSRDSQ 145
Cdd:COG4913    287 QRRLELLEAELEE---LRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRAR 363

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958672921  146 MSQALRLLeneHQELQTKLESLQGDREQQSSETQDLQDQLKKSEEERQALMSRV 199
Cdd:COG4913    364 LEALLAAL---GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL 414
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH