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Conserved domains on  [gi|1958762409|ref|XP_038961133|]
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1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 7.71e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


:

Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.46  E-value: 7.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958762409  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 7.71e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.46  E-value: 7.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958762409  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 4-158 8.99e-37

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 126.28  E-value: 8.99e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:COG0204    60 LLAALPRPVRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALRALRQAVEAL-KAGESLVIFPEGTRSPDGRLLPFKT 138

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958762409  84 GAFYLAIQAQVPIIPVVYSSfSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISE 158
Cdd:COG0204   139 GAARLALEAGVPIVPVAIDG-TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRA 212
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 1-102 7.78e-32

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 111.22  E-value: 7.78e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   1 MMGLMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGD 77
Cdd:pfam01553  28 VLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVELL-REGKLVVIFPEGTRSREGE 106

                          90       100
                  ....*....|....*....|....*
gi 1958762409  78 LLPFKKGAFYLAIQAQVPIIPVVYS 102
Cdd:pfam01553 107 LLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 4-102 1.52e-28

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 102.43  E-value: 1.52e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409    4 LMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLP 80
Cdd:smart00563  16 LSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELL-KEGEWLLIFPEGTRSRPGKLLP 94

                           90       100
                   ....*....|....*....|..
gi 1958762409   81 FKKGAFYLAIQAQVPIIPVVYS 102
Cdd:smart00563  95 FKKGAARLALEAGVPIVPVAIR 116
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 7-102 2.34e-24

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 92.02  E-value: 2.34e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   7 ILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKKGAF 86
Cdd:TIGR00530  36 AFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAIEVL-KQGRSIGVFPEGTRSRGRDILPFKKGAF 114

                          90
                  ....*....|....*.
gi 1958762409  87 YLAIQAQVPIIPVVYS 102
Cdd:TIGR00530 115 HIAIKAGVPILPVVLS 130
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 1-170 6.57e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 75.44  E-value: 6.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   1 MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTRNDNGDLLP 80
Cdd:PRK15018   79 MVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409  81 FKKGAFYLAIQAQVPIIPVVYSSFSSfyNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRAtflQISEIP 160
Cdd:PRK15018  159 FKTGAFHAAIAAGVPIIPVCVSTTSN--KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQ---KIAELD 233

                         170
                  ....*....|
gi 1958762409 161 QENSTIKESG 170
Cdd:PRK15018  234 KEVAEREAAG 243
 
Name Accession Description Interval E-value
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 4-137 7.71e-37

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 125.46  E-value: 7.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:cd07989    41 LGAALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRGNGRSAREALREAIEAL-KEGESVVIFPEGTRSRDGELLPFKS 119

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1958762409  84 GAFYLAIQAQVPIIPVVYSSFSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDAD 137
Cdd:cd07989   120 GAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGRVTVRIGEPIPPEGLELAE 173
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 4-158 8.99e-37

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 126.28  E-value: 8.99e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   4 LMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKK 83
Cdd:COG0204    60 LLAALPRPVRFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAALRALRQAVEAL-KAGESLVIFPEGTRSPDGRLLPFKT 138

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958762409  84 GAFYLAIQAQVPIIPVVYSSfSSFYNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRATFLQISE 158
Cdd:COG0204   139 GAARLALEAGVPIVPVAIDG-TERALPKGFLPRPGKVTVRIGPPIDPSDLEGEDRRELAERLRAAIEALLAELRA 212
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 1-102 7.78e-32

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 111.22  E-value: 7.78e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   1 MMGLMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGD 77
Cdd:pfam01553  28 VLLLSLALYKrgrPLVFVAKKELFDIPLVGWLMRLLGCIFIDRKNRKDAAGTLEYLVELL-REGKLVVIFPEGTRSREGE 106

                          90       100
                  ....*....|....*....|....*
gi 1958762409  78 LLPFKKGAFYLAIQAQVPIIPVVYS 102
Cdd:pfam01553 107 LLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 4-102 1.52e-28

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 102.43  E-value: 1.52e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409    4 LMEILPK---RCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLP 80
Cdd:smart00563  16 LSALLPRklgRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRKARAALREAVELL-KEGEWLLIFPEGTRSRPGKLLP 94

                           90       100
                   ....*....|....*....|..
gi 1958762409   81 FKKGAFYLAIQAQVPIIPVVYS 102
Cdd:smart00563  95 FKKGAARLALEAGVPIVPVAIR 116
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 7-102 2.34e-24

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 92.02  E-value: 2.34e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   7 ILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMvKENLKVWIYPEGTRNDNGDLLPFKKGAF 86
Cdd:TIGR00530  36 AFPPPIVFIAKKELKWIPFFGIMLWLTGAIFIDRENIRAIATALKAAIEVL-KQGRSIGVFPEGTRSRGRDILPFKKGAF 114

                          90
                  ....*....|....*.
gi 1958762409  87 YLAIQAQVPIIPVVYS 102
Cdd:TIGR00530 115 HIAIKAGVPILPVVLS 130
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 1-170 6.57e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 75.44  E-value: 6.57e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   1 MMGLMEILPKRCVQIAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTRNDNGDLLP 80
Cdd:PRK15018   79 MVTASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLP 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409  81 FKKGAFYLAIQAQVPIIPVVYSSFSSfyNVKTKLFTSGTIRVQVLDAVPTNGLTDADVTKLVDTCYQSMRAtflQISEIP 160
Cdd:PRK15018  159 FKTGAFHAAIAAGVPIIPVCVSTTSN--KINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQ---KIAELD 233

                         170
                  ....*....|
gi 1958762409 161 QENSTIKESG 170
Cdd:PRK15018  234 KEVAEREAAG 243
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 15-100 7.80e-12

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 60.90  E-value: 7.80e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409  15 IAKRELMFTGPVGLIMYLGGVYFINRQQAKTAMSLMADLGDLmVKENLKVWIYPEGTRNDNGDLLPFKKGAFYLAIQAQV 94
Cdd:PLN02901   77 ISKTSIFLIPIIGWAMYMTGHIPLKRMDRRSQLECLKRCMEL-LKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGV 155


                  ....*.
gi 1958762409  95 PIIPVV 100
Cdd:PLN02901  156 PVVPIT 161
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 33-100 1.69e-08

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 51.65  E-value: 1.69e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958762409  33 GGVYFINRQQAKTAMSLMADLGDLMVKENLKVWIYPEGTRNDNGD-LLPFKKGAFYLAIQAQVPIIPVV 100
Cdd:cd06551    73 LGAFSVDRDSPRSAAKSLKYVARLLSKPGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVA 141
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 1-99 2.11e-07

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 47.98  E-value: 2.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409   1 MMGLMEILpKRCVQIAKRELMFTGPVGLIM-YLGGVYfINRQQAktamslmADLGDLMVK-----ENLKVWIYPEGTRND 74
Cdd:cd07988    38 GLLAAFAL-GLKISFLGKHSLFKPPLGPFMrWLGGIP-VDRSRA-------GGLVEQVVEefrrrEEFVLAIAPEGTRSK 108

                          90       100
                  ....*....|....*....|....*
gi 1958762409  75 NGdllPFKKGAFYLAIQAQVPIIPV 99
Cdd:cd07988   109 VD---KWKTGFYHIARGAGVPILLV 130
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 15-109 3.09e-06

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 45.29  E-value: 3.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958762409  15 IAKRELMFTGPVGLIM-YLGGVYFiNRQQAKTAMS---LMADLGDLMvkENLKVWIYPEGTRNDNGDLLPFKKGAFYLai 90
Cdd:cd07991    50 VAKKELGKLPFIGTILrALGCIFV-DRSEPKDRKKvveEIKERATDP--NWPPILIFPEGTTTNGKALIMFKKGAFEP-- 124

                          90       100
                  ....*....|....*....|.
gi 1958762409  91 qaQVPIIPVV--YSSFSSFYN 109
Cdd:cd07991   125 --GVPVQPVAirYPNKFVDAF 143
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 64-105 4.00e-04

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 39.91  E-value: 4.00e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958762409   64 VWIYPEGTRNDNGDLLPFKKGaFYLAIQ-AQVPIIPvVY------SSFS 105
Cdd:PRK08633   514 VCIFPEGAITRNGQLNEFKRG-FELIVKgTDVPIIP-FYirglwgSIFS 560
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 66-99 8.00e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 35.73  E-value: 8.00e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1958762409  66 IYPEGTR-------NDNGDLLPFKKGAFYLAIQAQVPIIPV 99
Cdd:cd07987    94 IFPGGARealkskrEEYYLLWKKRKGFARLALRAGAPIVPV 134
LPLAT_DUF374-like cd07983
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; ...
 82-122 9.84e-03

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are the uncharacterized DUF374 phospholipid/glycerol acyltransferases and similar proteins.


Pssm-ID: 153245 [Multi-domain]  Cd Length: 189  Bit Score: 35.27  E-value: 9.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1958762409  82 KKGAFYLAIQAQVPIIPVVYsSFSSFYNVKT-------KLFTSGTIRV 122
Cdd:cd07983   115 KPGVILLARKSGAPIVPVAI-AASRAWRLKSwdrfiipKPFSRVVIVF 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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