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Conserved domains on  [gi|1958644846|ref|XP_038965391|]
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform X4 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CynX super family cl34489
Cyanate permease [Inorganic ion transport and metabolism];
123-247 6.91e-04

Cyanate permease [Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG2807:

Pssm-ID: 442057 [Multi-domain]  Cd Length: 399  Bit Score: 42.17  E-value: 6.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 123 ACAFFFLTCFLTRAQRGPDRGAGSW-----------WLLALPACCYLGDFAAWQwwSWL------RGEPAAAAAgrlcLV 185
Cdd:COG2807   182 LLALLLWLPLLRRRPAAAAAAPAAAslrslwrsplaWLLTLFFGLQSLLYYAVV--AWLppilrdAGLSAATAG----LL 255

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 186 LSCVGLLTLAPRV-------RLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVG-GAGCLLALGL 247
Cdd:COG2807   256 LSLFQLAGIPGSLlvplladRLGDRRPLLLLLGLLGLAGLLGLLLAPGSLPWLWAVLLGlGQGGLFPLAL 325
 
Name Accession Description Interval E-value
CynX COG2807
Cyanate permease [Inorganic ion transport and metabolism];
123-247 6.91e-04

Cyanate permease [Inorganic ion transport and metabolism];


Pssm-ID: 442057 [Multi-domain]  Cd Length: 399  Bit Score: 42.17  E-value: 6.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 123 ACAFFFLTCFLTRAQRGPDRGAGSW-----------WLLALPACCYLGDFAAWQwwSWL------RGEPAAAAAgrlcLV 185
Cdd:COG2807   182 LLALLLWLPLLRRRPAAAAAAPAAAslrslwrsplaWLLTLFFGLQSLLYYAVV--AWLppilrdAGLSAATAG----LL 255

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 186 LSCVGLLTLAPRV-------RLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVG-GAGCLLALGL 247
Cdd:COG2807   256 LSLFQLAGIPGSLlvplladRLGDRRPLLLLLGLLGLAGLLGLLLAPGSLPWLWAVLLGlGQGGLFPLAL 325
Exosortase_EpsH pfam09721
Transmembrane exosortase (Exosortase_EpsH); Members of this family are designated exosortase, ...
 149-232 7.55e-03

Transmembrane exosortase (Exosortase_EpsH); Members of this family are designated exosortase, analogous to sortase in cell wall sorting mediated by LPXTG domains in Gram-positive bacteria. The phylogenetic distribution of the proteins in this entry is nearly perfectly correlated with the distribution of the proteins having the PEP-CTERM anchor motif, IPR013424. Members of this entry are integral membrane proteins with eight predicted transmembrane helices in common. Some members of this family have long trailing sequences past the region described by this model. This model does not include the region of the first predicted transmembrane region. The best characterized member is EpsH of Methylobacillus sp. 12S, where it is part of a locus associated with biosynthesis of the exopolysaccharide methanol-an.


Pssm-ID: 430773  Cd Length: 250  Bit Score: 38.43  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 149 LLALPACCYLgdfaAWQWWSWLRGEPAAAAAGRLCLVLSCVGLLTLAPRVR---LRHGVLVLLFAGLVWWvsFSGLGALP 225
Cdd:pfam09721  23 LLVPPLALYL----VWRRWRRAALPPRPSWLGLLLLLAGLGLLWLLGRLAGvllLAQLSLVLLLAGLVLL--LLGWRALR 96


                  ....*..
gi 1958644846 226 PALRPLL 232
Cdd:pfam09721  97 ALWFPLL 103
 
Name Accession Description Interval E-value
CynX COG2807
Cyanate permease [Inorganic ion transport and metabolism];
123-247 6.91e-04

Cyanate permease [Inorganic ion transport and metabolism];


Pssm-ID: 442057 [Multi-domain]  Cd Length: 399  Bit Score: 42.17  E-value: 6.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 123 ACAFFFLTCFLTRAQRGPDRGAGSW-----------WLLALPACCYLGDFAAWQwwSWL------RGEPAAAAAgrlcLV 185
Cdd:COG2807   182 LLALLLWLPLLRRRPAAAAAAPAAAslrslwrsplaWLLTLFFGLQSLLYYAVV--AWLppilrdAGLSAATAG----LL 255

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 186 LSCVGLLTLAPRV-------RLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVG-GAGCLLALGL 247
Cdd:COG2807   256 LSLFQLAGIPGSLlvplladRLGDRRPLLLLLGLLGLAGLLGLLLAPGSLPWLWAVLLGlGQGGLFPLAL 325
Exosortase_EpsH pfam09721
Transmembrane exosortase (Exosortase_EpsH); Members of this family are designated exosortase, ...
 149-232 7.55e-03

Transmembrane exosortase (Exosortase_EpsH); Members of this family are designated exosortase, analogous to sortase in cell wall sorting mediated by LPXTG domains in Gram-positive bacteria. The phylogenetic distribution of the proteins in this entry is nearly perfectly correlated with the distribution of the proteins having the PEP-CTERM anchor motif, IPR013424. Members of this entry are integral membrane proteins with eight predicted transmembrane helices in common. Some members of this family have long trailing sequences past the region described by this model. This model does not include the region of the first predicted transmembrane region. The best characterized member is EpsH of Methylobacillus sp. 12S, where it is part of a locus associated with biosynthesis of the exopolysaccharide methanol-an.


Pssm-ID: 430773  Cd Length: 250  Bit Score: 38.43  E-value: 7.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958644846 149 LLALPACCYLgdfaAWQWWSWLRGEPAAAAAGRLCLVLSCVGLLTLAPRVR---LRHGVLVLLFAGLVWWvsFSGLGALP 225
Cdd:pfam09721  23 LLVPPLALYL----VWRRWRRAALPPRPSWLGLLLLLAGLGLLWLLGRLAGvllLAQLSLVLLLAGLVLL--LLGWRALR 96


                  ....*..
gi 1958644846 226 PALRPLL 232
Cdd:pfam09721  97 ALWFPLL 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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