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Conserved domains on  [gi|1985313511|ref|XP_039374259|]
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zinc finger protein 850-like isoform X1 [Mauremys reevesii]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 18089471)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development and in regulating viral replication and transcription

CATH:  3.30.160.60|1.10.287.1360
Gene Ontology:  GO:0005515|GO:0008270|GO:0003677|GO:0006355|GO:0001217|GO:0003700
PubMed:  8183940|22803940|2023909|8183939|10748030|27867147|28765213|11361095|30718982|10940247
SCOP:  4003583|4002243

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
489-882 4.11e-16

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 82.05  E-value: 4.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 489 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 565
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 566 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 645
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 646 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 725
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 726 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 792
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 793 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 861
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313511 862 ESFSKSSELTTHQKIHKGERP 882
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
KRAB super family cl42959
krueppel associated box;
1-32 2.03e-12

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.03e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313511    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
150-595 4.84e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.63  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 150 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 227
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 228 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 305
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 306 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 385
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 386 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 463
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 464 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 530
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313511 531 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 595
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
489-882 4.11e-16

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 82.05  E-value: 4.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 489 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 565
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 566 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 645
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 646 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 725
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 726 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 792
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 793 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 861
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313511 862 ESFSKSSELTTHQKIHKGERP 882
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
KRAB smart00349
krueppel associated box;
1-32 2.03e-12

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.03e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313511    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
150-595 4.84e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.63  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 150 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 227
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 228 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 305
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 306 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 385
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 386 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 463
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 464 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 530
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313511 531 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 595
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
281-306 2.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*.
gi 1985313511 281 HLTQHRKIHTGERPYKCLQCGKAFTQ 306
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 603-625 4.31e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 4.31e-03
                          10        20
                  ....*....|....*....|...
gi 1985313511 603 YKCLDCGKTFSQSSHLNKHRRIH 625
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
489-882 4.11e-16

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 82.05  E-value: 4.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 489 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 565
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 566 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 645
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 646 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 725
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 726 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 792
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 793 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 861
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313511 862 ESFSKSSELTTHQKIHKGERP 882
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
405-847 1.29e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.88  E-value: 1.29e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 405 RPYTCFECGKNFVDRTKLTRHQAIHTGEKPHKCLDCGksfirksqltvhqkvhaaegsykcleCGKTFIHNSKLTTHQRT 484
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSG--------------------------CDKSFSRPLELSRHLRT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 485 HRGERPYKCLNCGKTFthNSKLTKHQKTHTG-ERPYGCLECGKSFiqkSHLTTHQRTHTRERPYKCLECGKTFIHNSKLT 563
Cdd:COG5048    86 HHNNPSDLNSKSLPLS--NSKASSSSLSSSSsNSNDNNLLSSHSL---PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 564 THQRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGErPYKCLECGKSFFES 643
Cdd:COG5048   161 TPQSNSLHPPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 644 SSLIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGER-------PYKCLECGKSFVRQTFFIKHQR--IHTGE-- 712
Cdd:COG5048   240 LLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEsl 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 713 RPYKC--LDCGKTFSQSSQLTQHGRIHTGERPFKC--LECGKSFIQKSYLTRHQRVH-----TGERPFKCL--KCGKSFM 781
Cdd:COG5048   320 KPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFK 399

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1985313511 782 ESSPLTKHRRIHTGERP--YKCLECGKSFSLKSILNTHYKTHTGEKPHkCLECGKTFSQRSNLNQHGK 847
Cdd:COG5048   400 RDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPL-LCSILKSFRRDLDLSNHGK 466
KRAB smart00349
krueppel associated box;
1-32 2.03e-12

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.03e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313511    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
265-728 2.38e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 67.03  E-value: 2.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 265 KPHKCLECGKTFTQRIHLTQHRKIHTGERPYKCLQ--CGKAFTQRIHLTQHRKIHTGERHYKCLQCEKL--FSTRWNLIK 340
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLsnSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 341 HERTHTgekPYKCLDCGKTFGQSSYLIKHR--RIHTGERPYNCFECGKNFVDRTKFTRHQAIHAGERPytcfeCGKNFVD 418
Cdd:COG5048   112 SSSSNS---NDNNLLSSHSLPPSSRDPQLPdlLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSN 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 419 RTKLTRHQAIHTGEKPHKCLDCGKSFIRKSQLTVHQKVHAaegsykclecgktfihNSKLTTHQRTHRGERPYKCLNcgk 498
Cdd:COG5048   184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS----------------SSSLPLTTNSQLSPKSLLSQS--- 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 499 tftHNSKLTKHQKTHTGERPYGCLeCGKSFIQKSHLTTHQRTHTRER-PYKCLECGKTFIHNSKLTTHQRT--HTG--VR 573
Cdd:COG5048   245 ---PSSLSSSDSSSSASESPRSSL-PTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRSvnHSGesLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 574 PYGCLE--CGISFMESSSLIKHGRIHTGERPYKC--LDCGKTFSQSSHLNKHrrihggerpykclecgkSFFESSSLIKH 649
Cdd:COG5048   321 PFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPP-----------------QSLQQYKDLKN 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 650 ERIHVGERPykclECGKSFKESSSLTKHGRIHTGERP--YKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFSQS 727
Cdd:COG5048   384 DKKSETLSN----SCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459


                  .
gi 1985313511 728 S 728
Cdd:COG5048   460 D 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
377-781 1.49e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 61.25  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 377 RPYNCFECGKNFVDRTKFTRHQAIHAGERPYTCF--ECGKNFVDRTKLTRHQAIHTGEKPHKCLDCGKSfiRKSQLTVHQ 454
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPL--SNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 455 KVHAAEGSYKCL-----ECGKTFIHNSKLTTHQRTHRGERPYKclNCGKTFTHNSKLTKHQKTHTGERPygclecGKSFI 529
Cdd:COG5048   110 LSSSSSNSNDNNllsshSLPPSSRDPQLPDLLSISNLRNNPLP--GNNSSSVNTPQSNSLHPPLPANSL------SKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 530 QKSHLTTHQRTHTRERPYKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISF-------MESSSLIKHGRIHTGERP 602
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsqSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 603 YKCLDcGKTFSQSSHLNKHRRIHGGER-PYKCLECGKSFFESSSLIKHER--IHVGE--RPYKCLE--CGKSFKESSSLT 675
Cdd:COG5048   262 RSSLP-TASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALK 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 676 KHGRIHTGERPYKCLECGKSFVRQTFFIK-------HQRIHTGERPYKCLD--CGKTFSQSSQLTQHGRIHTGERP--FK 744
Cdd:COG5048   341 RHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1985313511 745 CLECGKSFIQKSYLTRHQRVHTGERPFKCLKCGKSFM 781
Cdd:COG5048   421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
150-595 4.84e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.63  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 150 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 227
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 228 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 305
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 306 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 385
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 386 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 463
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 464 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 530
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313511 531 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 595
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
209-621 5.46e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 56.24  E-value: 5.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 209 KPYKCLECGKSFSQSSYLTAHRRIHSGERPYKCLECGKSFNLKSTLN--THHKTHTGEKPHKCL-ECGKTFTQRIHLTQH 285
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLElsRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 286 RKIHTgeRPYKCLQCGKAFTQRIHLTQHRKIHTgERHYKCLQCEKLFSTRWNLIKHERTHtGEKPYKCLDCGKTFGQSSY 365
Cdd:COG5048   112 SSSSN--SNDNNLLSSHSLPPSSRDPQLPDLLS-ISNLRNNPLPGNNSSSVNTPQSNSLH-PPLPANSLSKDPSSNLSLL 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 366 LikHRRIHTGERPYNCFECGKNFVDRTKFTRHQAIHAGERPYTCFECGKNFVDRTKLTRHQAIHTGEKPHKCLDCG---- 441
Cdd:COG5048   188 I--SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrssl 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 442 --KSFIRKSQLTVHQKVHAAEG-SYKCLECGKTFIHNSKLTTHQRT--HRGE--RPYKC--LNCGKTFTHNSKLTKHQKT 512
Cdd:COG5048   266 ptASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 513 HTGERPYGC--LECGKSFIQKS----HLTTHQRTHTRERPYKC---LECGKTFIHNSKLTTHQRTHTGVRPYGC--LECG 581
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLLnnepPQSLQQYKDLKNDKKSEtlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCS 425

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1985313511 582 ISFMESSSLIKHGRIHTGERPYKCLDCGKtFSQSSHLNKH 621
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
139-399 1.43e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.09  E-value: 1.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 139 PKEITVQQTSHNEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKCVDCGKSFSEKSNFIVHQRLHI----------GE 208
Cdd:COG5048   208 SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPnesdsssekgFS 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 209 KPYKCLECGKSFSQSSYLTAHRR--IHSGE--RPYKCLE--CGKSFNLKSTLNTHHKTHTGEKPHKClecgktftqriHL 282
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKE-----------KL 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 283 TQHRKIHTGERPYKCLQCgkaftqrihLTQHRKIHTGERHYKCLQ-CEKLFSTRWNLIKHERTHTGEKP--YKCLDCGKT 359
Cdd:COG5048   357 LNSSSKFSPLLNNEPPQS---------LQQYKDLKNDKKSETLSNsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1985313511 360 FGQSSYLIKHRRIHTGERPYNCFECGKNFVDRTKFTRHQA 399
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 599-677 1.96e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 48.18  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 599 GERPYKC--LDCGKTFSQSSHLnKHRRIHGgerpykclECGKSFFESSSLIKHERIHVGERPYKCLECGKSFKESSSLTK 676
Cdd:COG5189   346 DGKPYKCpvEGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  .
gi 1985313511 677 H 677
Cdd:COG5189   417 H 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 472-570 7.16e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 43.17  E-value: 7.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 472 FIHNSKLTTHQRTHR----GERPYKC--LNCGKTFTHNSKLTKHQKthtgerpYGclECGKSFIQKSHLTTHQRTHTRER 545
Cdd:COG5189   327 LAHGGERNIDTPSRMlkvkDGKPYKCpvEGCNKKYKNQNGLKYHML-------HG--HQNQKLHENPSPEKMNIFSAKDK 397

                          90       100
                  ....*....|....*....|....*
gi 1985313511 546 PYKCLECGKTFIHNSKLTTHqRTHT 570
Cdd:COG5189   398 PYRCEVCDKRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
281-306 2.84e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.84e-03
                          10        20
                  ....*....|....*....|....*.
gi 1985313511 281 HLTQHRKIHTGERPYKCLQCGKAFTQ 306
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
337-360 3.78e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.78e-03
                          10        20
                  ....*....|....*....|....
gi 1985313511 337 NLIKHERTHTGEKPYKCLDCGKTF 360
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
148-500 3.88e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 3.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 148 SHNEEKPYKCLD--RGKSFHFSASLIKHWRTHTGEKS-----------------------------YKCVDCGKSFSEKS 196
Cdd:COG5048    55 SHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSdlnskslplsnskasssslsssssnsndnNLLSSHSLPPSSRD 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 197 NFI--VHQRLHIGEKPYK-CLECGKSFSQSSYLTA-HRRIHSGERPYKCLecgksfnlksTLNTHHKTHTGEKPHKCLEC 272
Cdd:COG5048   135 PQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLHPpLPANSLSKDPSSNL----------SLLISSNVSTSIPSSSENSP 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 273 GKTFTQRIHLTQHRKIHTGERPYKCLQCGkaFTQRIHLTQHRKIHTGERHYKCLQCEKLFSTRWNLIKHERTHTG----- 347
Cdd:COG5048   205 LSSSYSIPSSSSDQNLENSSSSLPLTTNS--QLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNEsdsss 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 348 ----EKPYKCLDCGKTFGQSSYLIKHRR--IHTGE--RPYNCFE--CGKNFVDRTKFTRHQAIHAGERPYTCFECGKNFV 417
Cdd:COG5048   283 ekgfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313511 418 DRTKLT-------RHQAIHTGEKPHKCLD--CGKSFIRKSQLTVHQKVHAAEGS--YKCLECGKTFIHNSKLTTHQRTHR 486
Cdd:COG5048   363 FSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442

                         410
                  ....*....|....
gi 1985313511 487 GERPYKCLNCGKTF 500
Cdd:COG5048   443 NHAPLLCSILKSFR 456
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 603-625 4.31e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 4.31e-03
                          10        20
                  ....*....|....*....|...
gi 1985313511 603 YKCLDCGKTFSQSSHLNKHRRIH 625
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-446 4.88e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313511 422 LTRHQAIHTGEKPHKCLDCGKSFIR 446
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
814-838 6.18e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.18e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313511 814 LNTHYKTHTGEKPHKCLECGKTFSQ 838
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
757-780 6.56e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.56e-03
                          10        20
                  ....*....|....*....|....
gi 1985313511 757 YLTRHQRVHTGERPFKCLKCGKSF 780
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
786-809 7.38e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.38e-03
                          10        20
                  ....*....|....*....|....
gi 1985313511 786 LTKHRRIHTGERPYKCLECGKSFS 809
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
254-278 7.67e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.67e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313511 254 LNTHHKTHTGEKPHKCLECGKTFTQ 278
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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