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Conserved domains on  [gi|1985313513|ref|XP_039374260|]
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zinc finger protein 850-like isoform X2 [Mauremys reevesii]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 18089471)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development and in regulating viral replication and transcription

CATH:  3.30.160.60|1.10.287.1360
Gene Ontology:  GO:0005515|GO:0008270|GO:0003677|GO:0006355|GO:0001217|GO:0003700
PubMed:  8183940|22803940|2023909|8183939|10748030|27867147|28765213|11361095|30718982|10940247
SCOP:  4003583|4002243

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
476-869 5.73e-16

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 81.67  E-value: 5.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 476 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 552
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 553 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 632
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 633 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 712
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 713 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 779
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 780 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 848
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313513 849 ESFSKSSELTTHQKIHKGERP 869
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
KRAB super family cl42959
krueppel associated box;
1-32 2.00e-12

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.00e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313513    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
137-582 6.88e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 137 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 214
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 215 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 292
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 293 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 372
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 373 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 450
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 451 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 517
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313513 518 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 582
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
476-869 5.73e-16

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 81.67  E-value: 5.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 476 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 552
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 553 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 632
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 633 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 712
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 713 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 779
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 780 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 848
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313513 849 ESFSKSSELTTHQKIHKGERP 869
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
KRAB smart00349
krueppel associated box;
1-32 2.00e-12

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.00e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313513    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
137-582 6.88e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 137 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 214
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 215 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 292
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 293 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 372
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 373 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 450
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 451 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 517
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313513 518 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 582
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
268-293 3.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 3.45e-03
                          10        20
                  ....*....|....*....|....*.
gi 1985313513 268 HLTQHRKIHTGERPYKCLQCGKAFTQ 293
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 590-612 5.02e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 5.02e-03
                          10        20
                  ....*....|....*....|...
gi 1985313513 590 YKCLDCGKTFSQSSHLNKHRRIH 612
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
476-869 5.73e-16

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 81.67  E-value: 5.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 476 RPYKCLNCGKTFTHNSKLTKHQKTHTGERPYGCL--ECGKSFIQKSHLTTHQRTHTRERPYKCL-ECGKTFIHNSKLTTH 552
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 553 QRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGERPykcleCGKSFFESSS 632
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 633 LIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGErPYKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFS 712
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 713 QSSQLTQHGRIHTGER-------PFKCLECGKSFIQKSYLTRHQR--VHTGE--RPFKC--LKCGKSFMESSPLTKHRRI 779
Cdd:COG5048   266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 780 HTGERPYKCLECGKSFSLKSILNT-------HYKTHTGEKPHKCL--ECGKTFSQRSNLNQHGKIHTRERP--YKCFDCG 848
Cdd:COG5048   346 HTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|.
gi 1985313513 849 ESFSKSSELTTHQKIHKGERP 869
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAP 446
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
392-834 1.73e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.49  E-value: 1.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 392 RPYTCFECGKNFVDRTKLTRHQAIHTGEKPHKCLDCGksfirksqltvhqkvhaaegsykcleCGKTFIHNSKLTTHQRT 471
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSG--------------------------CDKSFSRPLELSRHLRT 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 472 HRGERPYKCLNCGKTFthNSKLTKHQKTHTG-ERPYGCLECGKSFiqkSHLTTHQRTHTRERPYKCLECGKTFIHNSKLT 550
Cdd:COG5048    86 HHNNPSDLNSKSLPLS--NSKASSSSLSSSSsNSNDNNLLSSHSL---PPSSRDPQLPDLLSISNLRNNPLPGNNSSSVN 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 551 THQRTHTGVRPYGCLECGISFMESSSLIKHGRIHTGERPYKCLDCGKTFSQSSHLNKHRRIHGGErPYKCLECGKSFFES 630
Cdd:COG5048   161 TPQSNSLHPPLPANSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSS-SLPLTTNSQLSPKS 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 631 SSLIKHERIHVGERPYKCLECGKSFKESSSLTKHGRIHTGER-------PYKCLECGKSFVRQTFFIKHQR--IHTGE-- 699
Cdd:COG5048   240 LLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEsl 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 700 RPYKC--LDCGKTFSQSSQLTQHGRIHTGERPFKC--LECGKSFIQKSYLTRHQRVH-----TGERPFKCL--KCGKSFM 768
Cdd:COG5048   320 KPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFK 399

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1985313513 769 ESSPLTKHRRIHTGERP--YKCLECGKSFSLKSILNTHYKTHTGEKPHkCLECGKTFSQRSNLNQHGK 834
Cdd:COG5048   400 RDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPL-LCSILKSFRRDLDLSNHGK 466
KRAB smart00349
krueppel associated box;
1-32 2.00e-12

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 62.61  E-value: 2.00e-12
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1985313513    1 MQENYETVTSLGFPIPKPDLIARLERGEEPWV 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
252-715 3.45e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.64  E-value: 3.45e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 252 KPHKCLECGKTFTQRIHLTQHRKIHTGERPYKCLQ--CGKAFTQRIHLTQHRKIHTGERHYKCLQCEKL--FSTRWNLIK 327
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLsnSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 328 HERTHTgekPYKCLDCGKTFGQSSYLIKHR--RIHTGERPYNCFECGKNFVDRTKFTRHQAIHAGERPytcfeCGKNFVD 405
Cdd:COG5048   112 SSSSNS---NDNNLLSSHSLPPSSRDPQLPdlLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSN 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 406 RTKLTRHQAIHTGEKPHKCLDCGKSFIRKSQLTVHQKVHAaegsykclecgktfihNSKLTTHQRTHRGERPYKCLNcgk 485
Cdd:COG5048   184 LSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS----------------SSSLPLTTNSQLSPKSLLSQS--- 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 486 tftHNSKLTKHQKTHTGERPYGCLeCGKSFIQKSHLTTHQRTHTRER-PYKCLECGKTFIHNSKLTTHQRT--HTG--VR 560
Cdd:COG5048   245 ---PSSLSSSDSSSSASESPRSSL-PTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRSvnHSGesLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 561 PYGCLE--CGISFMESSSLIKHGRIHTGERPYKC--LDCGKTFSQSSHLNKHrrihggerpykclecgkSFFESSSLIKH 636
Cdd:COG5048   321 PFSCPYslCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPP-----------------QSLQQYKDLKN 383

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 637 ERIHVGERPykclECGKSFKESSSLTKHGRIHTGERP--YKCLECGKSFVRQTFFIKHQRIHTGERPYKCLDCGKTFSQS 714
Cdd:COG5048   384 DKKSETLSN----SCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459


                  .
gi 1985313513 715 S 715
Cdd:COG5048   460 D 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
364-768 2.00e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.86  E-value: 2.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 364 RPYNCFECGKNFVDRTKFTRHQAIHAGERPYTCF--ECGKNFVDRTKLTRHQAIHTGEKPHKCLDCGKSfiRKSQLTVHQ 441
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPL--SNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 442 KVHAAEGSYKCL-----ECGKTFIHNSKLTTHQRTHRGERPYKclNCGKTFTHNSKLTKHQKTHTGERPygclecGKSFI 516
Cdd:COG5048   110 LSSSSSNSNDNNllsshSLPPSSRDPQLPDLLSISNLRNNPLP--GNNSSSVNTPQSNSLHPPLPANSL------SKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 517 QKSHLTTHQRTHTRERPYKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISF-------MESSSLIKHGRIHTGERP 589
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsqSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 590 YKCLDcGKTFSQSSHLNKHRRIHGGER-PYKCLECGKSFFESSSLIKHER--IHVGE--RPYKCLE--CGKSFKESSSLT 662
Cdd:COG5048   262 RSSLP-TASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALK 340

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 663 KHGRIHTGERPYKCLECGKSFVRQTFFIK-------HQRIHTGERPYKCLD--CGKTFSQSSQLTQHGRIHTGERP--FK 731
Cdd:COG5048   341 RHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 1985313513 732 CLECGKSFIQKSYLTRHQRVHTGERPFKCLKCGKSFM 768
Cdd:COG5048   421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRR 457
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
137-582 6.88e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 137 NEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKC--VDCGKSFSEKSNFIVHQRLHIGEKPYKCLecgKSFSQSSYLT 214
Cdd:COG5048    29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS---KSLPLSNSKA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 215 AHR--RIHSGERPYKCLECGKSFNLKSTLNTHHKTHTGEKPHKCLECGKTFTQRIHLTQHRKIHTGERPykcLQCGKAFT 292
Cdd:COG5048   106 SSSslSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---SLSKDPSS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 293 QRIHLTQHRKIHTGERHYKCLQCEKLFStRWNLIKHERTHTGEKPYKCLDCGKTFGQSSYLIKHRRIHTGERPYNCFECG 372
Cdd:COG5048   183 NLSLLISSNVSTSIPSSSENSPLSSSYS-IPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 373 KNFVDRTKFTRHQAIHagerpytcfecgKNFVDRTKLTrhqaihtgeKPHKCLDCGKSFIRKSQLTVHQ--KVHAAEGSY 450
Cdd:COG5048   262 RSSLPTASSQSSSPNE------------SDSSSEKGFS---------LPIKSKQCNISFSRSSPLTRHLrsVNHSGESLK 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 451 KCLE----CGKTFIHNSKLTTHQRTHRGERPYKCLNCGKTFTHNSKLTK-------HQKTHTGERPYGCL--ECGKSFIQ 517
Cdd:COG5048   321 PFSCpyslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLsnSCIRNFKR 400

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1985313513 518 KSHLTTHQRTHTRERP--YKCLECGKTFIHNSKLTTHQRTHTGVRPYGCLECGISFmESSSLIKHGR 582
Cdd:COG5048   401 DSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFR-RDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
196-608 7.31e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 7.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 196 KPYKCLECGKSFSQSSYLTAHRRIHSGERPYKCLECGKSFNLKSTLN--THHKTHTGEKPHKCL-ECGKTFTQRIHLTQH 272
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLElsRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 273 RKIHTgeRPYKCLQCGKAFTQRIHLTQHRKIHTgERHYKCLQCEKLFSTRWNLIKHERTHtGEKPYKCLDCGKTFGQSSY 352
Cdd:COG5048   112 SSSSN--SNDNNLLSSHSLPPSSRDPQLPDLLS-ISNLRNNPLPGNNSSSVNTPQSNSLH-PPLPANSLSKDPSSNLSLL 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 353 LikHRRIHTGERPYNCFECGKNFVDRTKFTRHQAIHAGERPYTCFECGKNFVDRTKLTRHQAIHTGEKPHKCLDCG---- 428
Cdd:COG5048   188 I--SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPrssl 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 429 --KSFIRKSQLTVHQKVHAAEG-SYKCLECGKTFIHNSKLTTHQRT--HRGE--RPYKC--LNCGKTFTHNSKLTKHQKT 499
Cdd:COG5048   266 ptASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 500 HTGERPYGC--LECGKSFIQKS----HLTTHQRTHTRERPYKC---LECGKTFIHNSKLTTHQRTHTGVRPYGC--LECG 568
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLLnnepPQSLQQYKDLKNDKKSEtlsNSCIRNFKRDSNLSLHIITHLSFRPYNCknPPCS 425

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1985313513 569 ISFMESSSLIKHGRIHTGERPYKCLDCGKtFSQSSHLNKH 608
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
126-386 1.77e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.70  E-value: 1.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 126 PKEITVQQTSHNEEKPYKCLDRGKSFHFSASLIKHWRTHTGEKSYKCVDCGKSFSEKSNFIVHQRLHI----------GE 195
Cdd:COG5048   208 SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPnesdsssekgFS 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 196 KPYKCLECGKSFSQSSYLTAHRR--IHSGE--RPYKCLE--CGKSFNLKSTLNTHHKTHTGEKPHKClecgktftqriHL 269
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKE-----------KL 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 270 TQHRKIHTGERPYKCLQCgkaftqrihLTQHRKIHTGERHYKCLQ-CEKLFSTRWNLIKHERTHTGEKP--YKCLDCGKT 346
Cdd:COG5048   357 LNSSSKFSPLLNNEPPQS---------LQQYKDLKNDKKSETLSNsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1985313513 347 FGQSSYLIKHRRIHTGERPYNCFECGKNFVDRTKFTRHQA 386
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGKD 467
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 586-664 2.09e-05

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 47.79  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 586 GERPYKC--LDCGKTFSQSSHLnKHRRIHGgerpykclECGKSFFESSSLIKHERIHVGERPYKCLECGKSFKESSSLTK 663
Cdd:COG5189   346 DGKPYKCpvEGCNKKYKNQNGL-KYHMLHG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  .
gi 1985313513 664 H 664
Cdd:COG5189   417 H 417
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 459-557 7.67e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 7.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 459 FIHNSKLTTHQRTHR----GERPYKC--LNCGKTFTHNSKLTKHQKthtgerpYGclECGKSFIQKSHLTTHQRTHTRER 532
Cdd:COG5189   327 LAHGGERNIDTPSRMlkvkDGKPYKCpvEGCNKKYKNQNGLKYHML-------HG--HQNQKLHENPSPEKMNIFSAKDK 397

                          90       100
                  ....*....|....*....|....*
gi 1985313513 533 PYKCLECGKTFIHNSKLTTHqRTHT 557
Cdd:COG5189   398 PYRCEVCDKRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
268-293 3.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 3.45e-03
                          10        20
                  ....*....|....*....|....*.
gi 1985313513 268 HLTQHRKIHTGERPYKCLQCGKAFTQ 293
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
324-347 4.58e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 4.58e-03
                          10        20
                  ....*....|....*....|....
gi 1985313513 324 NLIKHERTHTGEKPYKCLDCGKTF 347
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 590-612 5.02e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 34.97  E-value: 5.02e-03
                          10        20
                  ....*....|....*....|...
gi 1985313513 590 YKCLDCGKTFSQSSHLNKHRRIH 612
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
135-487 5.11e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.45  E-value: 5.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 135 SHNEEKPYKCLD--RGKSFHFSASLIKHWRTHTGEKS-----------------------------YKCVDCGKSFSEKS 183
Cdd:COG5048    55 SHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSdlnskslplsnskasssslsssssnsndnNLLSSHSLPPSSRD 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 184 NFI--VHQRLHIGEKPYK-CLECGKSFSQSSYLTA-HRRIHSGERPYKCLecgksfnlksTLNTHHKTHTGEKPHKCLEC 259
Cdd:COG5048   135 PQLpdLLSISNLRNNPLPgNNSSSVNTPQSNSLHPpLPANSLSKDPSSNL----------SLLISSNVSTSIPSSSENSP 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 260 GKTFTQRIHLTQHRKIHTGERPYKCLQCGkaFTQRIHLTQHRKIHTGERHYKCLQCEKLFSTRWNLIKHERTHTG----- 334
Cdd:COG5048   205 LSSSYSIPSSSSDQNLENSSSSLPLTTNS--QLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNEsdsss 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 335 ----EKPYKCLDCGKTFGQSSYLIKHRR--IHTGE--RPYNCFE--CGKNFVDRTKFTRHQAIHAGERPYTCFECGKNFV 404
Cdd:COG5048   283 ekgfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSK 362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1985313513 405 DRTKLT-------RHQAIHTGEKPHKCLD--CGKSFIRKSQLTVHQKVHAAEGS--YKCLECGKTFIHNSKLTTHQRTHR 473
Cdd:COG5048   363 FSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT 442

                         410
                  ....*....|....
gi 1985313513 474 GERPYKCLNCGKTF 487
Cdd:COG5048   443 NHAPLLCSILKSFR 456
zf-H2C2_2 pfam13465
Zinc-finger double domain;
409-433 6.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.03e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313513 409 LTRHQAIHTGEKPHKCLDCGKSFIR 433
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
801-825 7.27e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.27e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313513 801 LNTHYKTHTGEKPHKCLECGKTFSQ 825
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
744-767 7.94e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.94e-03
                          10        20
                  ....*....|....*....|....
gi 1985313513 744 YLTRHQRVHTGERPFKCLKCGKSF 767
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
241-265 9.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 9.11e-03
                          10        20
                  ....*....|....*....|....*
gi 1985313513 241 LNTHHKTHTGEKPHKCLECGKTFTQ 265
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
773-796 9.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 9.11e-03
                          10        20
                  ....*....|....*....|....
gi 1985313513 773 LTKHRRIHTGERPYKCLECGKSFS 796
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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