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Conserved domains on  [gi|2201727779|ref|XP_046765997|]
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myocardin-related transcription factor A isoform X3 [Gallus gallus]

Protein Classification

SAP domain-containing protein( domain architecture ID 10653801)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 349-382 2.51e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


:

Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 56.25  E-value: 2.51e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2201727779  349 LDEMKVAELKQELKLRALPVSGTKTDLIERLRAY 382
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
24-49 4.33e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 44.00  E-value: 4.33e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    24 DYLKRKIRSRPERSELVRMHILEETS 49
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 5.16e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


:

Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.62  E-value: 5.16e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    68 DDLNEKIAQRPGPMELVEKNILPVES 93
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
PLN03124 super family cl33640
poly [ADP-ribose] polymerase; Provisional
 299-418 4.89e-03

poly [ADP-ribose] polymerase; Provisional


The actual alignment was detected with superfamily member PLN03124:

Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 40.98  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201727779  299 GEQQTGASAPAVRNLSAAV---NSTSSVSSGSSGLMRQNSNAAVGKPGPLP--------ANLDEMKVAELKQELKLRALP 367
Cdd:PLN03124    18 GLDTTGLKAALVRRLDDAIaedAKTASKSGTKSSAGRKKRRERQDDGDDEPvspkriaiDEVKGMTVRELREAASERGLA 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201727779  368 VSGTKTDLIERLRAYQEQNGTAGQTTPT----PKPSTAAILPKAAEVVVAFPAAR 418
Cdd:PLN03124    98 TTGRKKDLLERLCAALESDVKVGSANGTgedeKEKGGDEEREKEEKIVTATKKGR 152
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 349-382 2.51e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 56.25  E-value: 2.51e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2201727779  349 LDEMKVAELKQELKLRALPVSGTKTDLIERLRAY 382
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
349-382 6.70e-09

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 52.10  E-value: 6.70e-09
                            10        20        30
                    ....*....|....*....|....*....|....
gi 2201727779   349 LDEMKVAELKQELKLRALPVSGTKTDLIERLRAY 382
Cdd:smart00513    1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLLEA 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
24-49 4.33e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 44.00  E-value: 4.33e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    24 DYLKRKIRSRPERSELVRMHILEETS 49
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 5.16e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.62  E-value: 5.16e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    68 DDLNEKIAQRPGPMELVEKNILPVES 93
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 69-90 2.58e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.88  E-value: 2.58e-05
                           10        20
                   ....*....|....*....|..
gi 2201727779   69 DLNEKIAQRPGPMELVEKNILP 90
Cdd:pfam02755    1 SLERKLSHRPTREELVERNILP 22
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 26-48 1.98e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.18  E-value: 1.98e-04
                           10        20
                   ....*....|....*....|...
gi 2201727779   26 LKRKIRSRPERSELVRMHILEET 48
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPED 24
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
 299-418 4.89e-03

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 40.98  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201727779  299 GEQQTGASAPAVRNLSAAV---NSTSSVSSGSSGLMRQNSNAAVGKPGPLP--------ANLDEMKVAELKQELKLRALP 367
Cdd:PLN03124    18 GLDTTGLKAALVRRLDDAIaedAKTASKSGTKSSAGRKKRRERQDDGDDEPvspkriaiDEVKGMTVRELREAASERGLA 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201727779  368 VSGTKTDLIERLRAYQEQNGTAGQTTPT----PKPSTAAILPKAAEVVVAFPAAR 418
Cdd:PLN03124    98 TTGRKKDLLERLCAALESDVKVGSANGTgedeKEKGGDEEREKEEKIVTATKKGR 152
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 349-382 2.51e-10

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 56.25  E-value: 2.51e-10
                           10        20        30
                   ....*....|....*....|....*....|....
gi 2201727779  349 LDEMKVAELKQELKLRALPVSGTKTDLIERLRAY 382
Cdd:pfam02037    1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
349-382 6.70e-09

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 52.10  E-value: 6.70e-09
                            10        20        30
                    ....*....|....*....|....*....|....
gi 2201727779   349 LDEMKVAELKQELKLRALPVSGTKTDLIERLRAY 382
Cdd:smart00513    1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLLEA 34
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
24-49 4.33e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 44.00  E-value: 4.33e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    24 DYLKRKIRSRPERSELVRMHILEETS 49
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL smart00707
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;
68-93 5.16e-06

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;


Pssm-ID: 128947  Cd Length: 26  Bit Score: 43.62  E-value: 5.16e-06
                            10        20
                    ....*....|....*....|....*.
gi 2201727779    68 DDLNEKIAQRPGPMELVEKNILPVES 93
Cdd:smart00707    1 DVLNRKLSQRPTREELEERNILKELS 26
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 69-90 2.58e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 41.88  E-value: 2.58e-05
                           10        20
                   ....*....|....*....|..
gi 2201727779   69 DLNEKIAQRPGPMELVEKNILP 90
Cdd:pfam02755    1 SLERKLSHRPTREELVERNILP 22
RPEL pfam02755
RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...
 26-48 1.98e-04

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.


Pssm-ID: 460677  Cd Length: 24  Bit Score: 39.18  E-value: 1.98e-04
                           10        20
                   ....*....|....*....|...
gi 2201727779   26 LKRKIRSRPERSELVRMHILEET 48
Cdd:pfam02755    2 LERKLSHRPTREELVERNILPED 24
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
 299-418 4.89e-03

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 40.98  E-value: 4.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201727779  299 GEQQTGASAPAVRNLSAAV---NSTSSVSSGSSGLMRQNSNAAVGKPGPLP--------ANLDEMKVAELKQELKLRALP 367
Cdd:PLN03124    18 GLDTTGLKAALVRRLDDAIaedAKTASKSGTKSSAGRKKRRERQDDGDDEPvspkriaiDEVKGMTVRELREAASERGLA 97

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201727779  368 VSGTKTDLIERLRAYQEQNGTAGQTTPT----PKPSTAAILPKAAEVVVAFPAAR 418
Cdd:PLN03124    98 TTGRKKDLLERLCAALESDVKVGSANGTgedeKEKGGDEEREKEEKIVTATKKGR 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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