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Conserved domains on  [gi|2201812098|ref|XP_046777802|]
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leucine-rich repeat flightless-interacting protein 1 isoform X5 [Gallus gallus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRRFIP super family cl26610
LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the ...
 165-408 3.32e-48

LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin.


The actual alignment was detected with superfamily member pfam09738:

Pssm-ID: 462869 [Multi-domain]  Cd Length: 303  Bit Score: 174.11  E-value: 3.32e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  165 EERPEKDF----------EKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDiyelkeqiqdvegkymq 234
Cdd:pfam09738   31 EENADRVFdmssssgadtASGSPTASTTSAGTLNSLGGTSSRRSSEDSSISLEDEGSLRDIKH----------------- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  235 glkemkdSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFK 314
Cdd:pfam09738   94 -------ELKEVEEKYRKAMISNAQLDNEKSNLMYQVDLLKDKLEEMEESLAELQRELREKNKELERLKRNLRRLQFQLA 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  315 EIKEALKQREEMLAE----IQQLQQKQQSYVREISDL------QETIE-WKDKKIGALE-RQKDFFDsirsERDDLRDEV 382
Cdd:pfam09738  167 ELKEQLKQRDELIEKhglvIVPDENTNGEEENSPADAkralvsVEAAEvLESAGEGSLDvRLKKLAD----EKEELLDEV 242

                          250       260
                   ....*....|....*....|....*....
gi 2201812098  383 IMLKEQL---KKHGIIPDSDIATNGEASD 408
Cdd:pfam09738  243 RKLKLQLeeeKSKRNSTRSSQSPDGFGLE 271
2A1904 super family cl36772
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 781-1075 4.40e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


The actual alignment was detected with superfamily member TIGR00927:

Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 57.70  E-value: 4.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  781 EACSDPAEKQEKASESVGSANEVEGNVLHQTEPDmdsvkemAAQETSLDPVSDDEieetemQTGDVSGKGEGnriEDLEH 860
Cdd:TIGR00927  633 GDVAEAEHTGERTGEEGERPTEAEGENGEESGGE-------AEQEGETETKGENE------SEGEIPAERKG---EQEGE 696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  861 NTTEDLKPKAELQTVQCSEETTGDTEDEkNTSLESEAQNvdkQEEGESKEESivchsvmSESQVDKEALKENKKESEPAD 940
Cdd:TIGR00927  697 GEIEAKEADHKGETEAEEVEHEGETEAE-GTEDEGEIET---GEEGEEVEDE-------GEGEAEGKHEVETEGDRKETE 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  941 HQGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNS 1020
Cdd:TIGR00927  766 HEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEA 845

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201812098 1021 VIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDE 1075
Cdd:TIGR00927  846 KQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPE 900
 
Name Accession Description Interval E-value
LRRFIP pfam09738
LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the ...
 165-408 3.32e-48

LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin.


Pssm-ID: 462869 [Multi-domain]  Cd Length: 303  Bit Score: 174.11  E-value: 3.32e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  165 EERPEKDF----------EKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDiyelkeqiqdvegkymq 234
Cdd:pfam09738   31 EENADRVFdmssssgadtASGSPTASTTSAGTLNSLGGTSSRRSSEDSSISLEDEGSLRDIKH----------------- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  235 glkemkdSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFK 314
Cdd:pfam09738   94 -------ELKEVEEKYRKAMISNAQLDNEKSNLMYQVDLLKDKLEEMEESLAELQRELREKNKELERLKRNLRRLQFQLA 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  315 EIKEALKQREEMLAE----IQQLQQKQQSYVREISDL------QETIE-WKDKKIGALE-RQKDFFDsirsERDDLRDEV 382
Cdd:pfam09738  167 ELKEQLKQRDELIEKhglvIVPDENTNGEEENSPADAkralvsVEAAEvLESAGEGSLDvRLKKLAD----EKEELLDEV 242

                          250       260
                   ....*....|....*....|....*....
gi 2201812098  383 IMLKEQL---KKHGIIPDSDIATNGEASD 408
Cdd:pfam09738  243 RKLKLQLeeeKSKRNSTRSSQSPDGFGLE 271
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 781-1075 4.40e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 57.70  E-value: 4.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  781 EACSDPAEKQEKASESVGSANEVEGNVLHQTEPDmdsvkemAAQETSLDPVSDDEieetemQTGDVSGKGEGnriEDLEH 860
Cdd:TIGR00927  633 GDVAEAEHTGERTGEEGERPTEAEGENGEESGGE-------AEQEGETETKGENE------SEGEIPAERKG---EQEGE 696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  861 NTTEDLKPKAELQTVQCSEETTGDTEDEkNTSLESEAQNvdkQEEGESKEESivchsvmSESQVDKEALKENKKESEPAD 940
Cdd:TIGR00927  697 GEIEAKEADHKGETEAEEVEHEGETEAE-GTEDEGEIET---GEEGEEVEDE-------GEGEAEGKHEVETEGDRKETE 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  941 HQGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNS 1020
Cdd:TIGR00927  766 HEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEA 845

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201812098 1021 VIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDE 1075
Cdd:TIGR00927  846 KQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPE 900
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 812-1114 8.89e-07

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 53.37  E-value: 8.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  812 EPDMDSVKEMAAQETSLDPVSDDEIEETEMQTGDVSGKGEG-----NRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTE 886
Cdd:NF033609   547 QPDEPGEIEPIPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTsdsgsDSASDSDSASDSDSASDSDSASDSDSASDSDSAS 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  887 DEKNTSLESEAQNVDKQEEGESKEESIVCHSVMSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENV 966
Cdd:NF033609   627 DSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 706

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  967 SEQLKLEGQAEEEQEDDGDA-FDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLT 1045
Cdd:NF033609   707 DSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 786

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2201812098 1046 EDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKED 1114
Cdd:NF033609   787 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 855
PTZ00121 PTZ00121
MAEBL; Provisional
 763-1095 2.78e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  763 ELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNvlHQTEPDMDSVKEMAAQETSLDPVSDDEIEETEMQ 842
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA--EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  843 TGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEEttgdtedekntslESEAQNVDKQEEGESKEesivCHSVMSES 922
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE-------------AKKAEELKKKEAEEKKK----AEELKKAE 1725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  923 QVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDgdafdfDEDSEQTAETDEK 1002
Cdd:PTZ00121  1726 EENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD------EEDEKRRMEVDKK 1799

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098 1003 CDGEEVDAQS--EEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQ-HKEGNESEETELSQEEASA------LET 1073
Cdd:PTZ00121  1800 IKDIFDNFANiiEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEkHKFNKNNENGEDGNKEADFnkekdlKED 1879

                          330       340
                   ....*....|....*....|..
gi 2201812098 1074 DEKADVLADEDKASDPNEVEKE 1095
Cdd:PTZ00121  1880 DEEEIEEADEIEKIDKDDIERE 1901
BMS1 COG5192
GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and ...
 681-1102 5.26e-03

GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227519 [Multi-domain]  Cd Length: 1077  Bit Score: 40.88  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  681 CTGGTADKTGGDRAGEQNEV----GSAVQGQKMERDSTGLEGEESCESgapSDPNEEGGDQahiqpvssevgelvllEEQ 756
Cdd:COG5192    305 CPPPDADHGRRRRLSLKSKLiyspMSDIGGILKDKDRVYIEVPTSNFS---KDENSEAGEG----------------EKM 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  757 NTQEQTELKPAEKDGQEEVLIGNLEAcSDPAEKQEKASESVG--SANEVEGNVLHQTEPDMDsvkEMAAQETSLDPVSDD 834
Cdd:COG5192    366 KMQLQEIEQDPGVDGVGLQLFSNSDA-IDTVDRESSEIDNVGrkTRRQPTGKAIAEETSRED---ELSFDDSDVSTSDEN 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  835 EIEETEMQTGDVSGKGE-GNRIEDLEHNTTEDlkpkaelqtvqcseettgdtEDEKNTSLESEAQNVDKQEEGESKEESI 913
Cdd:COG5192    442 EDVDFTGKKGAINNEDEsDNEEVAFDSDSQFD--------------------ESEGNLRWKEGLASKLAYSQSGKRGRNI 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  914 VCHSVMsESQVDKEALKENKKESEPA--------DHQGDGFTSVEDADSSLALKAE-LDENVSEQL--KLEGQAEEEQED 982
Cdd:COG5192    502 QKIFYD-ESLSPEECIEEYKGESAKSsesdlvvqDEPEDFFDVSKVANESISSNHEkLMESEFEELkkKWSSLAQLKSRF 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  983 DGDA-FDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSgkietsdtlTEDDSLQHKEGNESEET 1061
Cdd:COG5192    581 QKDAtLDSIEGEEELIQDDEKGNFEDLEDEENSSDNEMEESRGSSVTAENEESA---------DEVDYETEREENARKKE 651

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2201812098 1062 ELSQEeasaLETDEKADvlaDEDKASDPNEVEKEPGEQDLE 1102
Cdd:COG5192    652 ELRGN----FELEERGD---PEKKDVDWYTEEKRKIEEQLK 685
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 947-1047 8.54e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 40.30  E-value: 8.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  947 TSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDaqseEDDRTNSVIRKTA 1026
Cdd:pfam04931  620 LDVLDARENPEGQQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVD----EIDELRAKLAEAL 695

                           90       100
                   ....*....|....*....|.
gi 2201812098 1027 QTGEAGEGSGKIETSDTLTED 1047
Cdd:pfam04931  696 GEHGDDADDDDSDSDEDMDDE 716
 
Name Accession Description Interval E-value
LRRFIP pfam09738
LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the ...
 165-408 3.32e-48

LRRFIP family; LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin.


Pssm-ID: 462869 [Multi-domain]  Cd Length: 303  Bit Score: 174.11  E-value: 3.32e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  165 EERPEKDF----------EKGARTVSSLSAATLASLGGTSSRRGSGDTSISADTEASIREIKDiyelkeqiqdvegkymq 234
Cdd:pfam09738   31 EENADRVFdmssssgadtASGSPTASTTSAGTLNSLGGTSSRRSSEDSSISLEDEGSLRDIKH----------------- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  235 glkemkdSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDALLELEEQLAESRRQYEEKSKEFEREKHAHSILQFQFK 314
Cdd:pfam09738   94 -------ELKEVEEKYRKAMISNAQLDNEKSNLMYQVDLLKDKLEEMEESLAELQRELREKNKELERLKRNLRRLQFQLA 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  315 EIKEALKQREEMLAE----IQQLQQKQQSYVREISDL------QETIE-WKDKKIGALE-RQKDFFDsirsERDDLRDEV 382
Cdd:pfam09738  167 ELKEQLKQRDELIEKhglvIVPDENTNGEEENSPADAkralvsVEAAEvLESAGEGSLDvRLKKLAD----EKEELLDEV 242

                          250       260
                   ....*....|....*....|....*....
gi 2201812098  383 IMLKEQL---KKHGIIPDSDIATNGEASD 408
Cdd:pfam09738  243 RKLKLQLeeeKSKRNSTRSSQSPDGFGLE 271
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 781-1075 4.40e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 57.70  E-value: 4.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  781 EACSDPAEKQEKASESVGSANEVEGNVLHQTEPDmdsvkemAAQETSLDPVSDDEieetemQTGDVSGKGEGnriEDLEH 860
Cdd:TIGR00927  633 GDVAEAEHTGERTGEEGERPTEAEGENGEESGGE-------AEQEGETETKGENE------SEGEIPAERKG---EQEGE 696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  861 NTTEDLKPKAELQTVQCSEETTGDTEDEkNTSLESEAQNvdkQEEGESKEESivchsvmSESQVDKEALKENKKESEPAD 940
Cdd:TIGR00927  697 GEIEAKEADHKGETEAEEVEHEGETEAE-GTEDEGEIET---GEEGEEVEDE-------GEGEAEGKHEVETEGDRKETE 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  941 HQGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNS 1020
Cdd:TIGR00927  766 HEGETEAEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEA 845

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2201812098 1021 VIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETELSQEEASALETDE 1075
Cdd:TIGR00927  846 KQDEKGVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPE 900
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 712-997 9.20e-08

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 56.54  E-value: 9.20e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  712 DSTGLEGEESCESGAPSDpnEEGGDQAHIQPVSSEVGElvlleeqntQEQTELKPAEKDGQEEvlignleacsDPAEKQE 791
Cdd:TIGR00927  643 ERTGEEGERPTEAEGENG--EESGGEAEQEGETETKGE---------NESEGEIPAERKGEQE----------GEGEIEA 701

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  792 KASESVGSANEVEGNVLHQTEPDMDSVK-EMAAQETSLDPVSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKA 870
Cdd:TIGR00927  702 KEADHKGETEAEEVEHEGETEAEGTEDEgEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEG 781

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  871 ELQTVQcSEETTGDTEDEKNTSLESEAQNVDKQEEGESKEESIVCHSVMSESQvDKEALKENKKESEPADHQGDGFTSVE 950
Cdd:TIGR00927  782 EIQAGE-DGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETG-EQELNAENQGEAKQDEKGVDGGGGSD 859

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 2201812098  951 DADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTA 997
Cdd:TIGR00927  860 GGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPLSLEWPETRQKQA 906
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 841-1114 8.33e-07

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 53.46  E-value: 8.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  841 MQTGDVSgKGEGNRIEDLEHNTTEDlkpkaelqtvqcsEETTGDTEDEKNTSLESEAQNvdkQEEGESKEESIVCHSVMS 920
Cdd:TIGR00927  625 MALGDLS-KGDVAEAEHTGERTGEE-------------GERPTEAEGENGEESGGEAEQ---EGETETKGENESEGEIPA 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  921 ESQVDKEAlkENKKESEPADHQGDgfTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAfDFDEDSEQTAETD 1000
Cdd:TIGR00927  688 ERKGEQEG--EGEIEAKEADHKGE--TEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEA-EGKHEVETEGDRK 762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098 1001 EKCDGEEVDAQSEEDDRTNSVirktaQTGEAGEGSG------KIETSDTLTEDDSLQHKEG-----------NESEETEL 1063
Cdd:TIGR00927  763 ETEHEGETEAEGKEDEDEGEI-----QAGEDGEMKGdegaegKVEHEGETEAGEKDEHEGQsetqaddtevkDETGEQEL 837

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2201812098 1064 SQEEASALETDEKAdvlADEDKASDPNEVEKEPGEQDLESAGCSRAESKED 1114
Cdd:TIGR00927  838 NAENQGEAKQDEKG---VDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEE 885
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 812-1114 8.89e-07

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 53.37  E-value: 8.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  812 EPDMDSVKEMAAQETSLDPVSDDEIEETEMQTGDVSGKGEG-----NRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTE 886
Cdd:NF033609   547 QPDEPGEIEPIPEDSDSDPGSDSGSDSSNSDSGSDSGSDSTsdsgsDSASDSDSASDSDSASDSDSASDSDSASDSDSAS 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  887 DEKNTSLESEAQNVDKQEEGESKEESIVCHSVMSESQVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENV 966
Cdd:NF033609   627 DSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 706

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  967 SEQLKLEGQAEEEQEDDGDA-FDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLT 1045
Cdd:NF033609   707 DSDSDSDSDSDSDSDSDSDSdSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 786

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2201812098 1046 EDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAGCSRAESKED 1114
Cdd:NF033609   787 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 855
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 691-938 1.70e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 52.31  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  691 GDRAGEQNEVGSAVQGQKMERDSTGLE--------GEESCESGAPSDPNEEGGDQAHIQPVSSEVGELVLLEEQNTQEQT 762
Cdd:TIGR00927  642 GERTGEEGERPTEAEGENGEESGGEAEqegetetkGENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAEEVEHEGET 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  763 ELKPAEKDGQEEVLIGNlEACSDPAEKQEKASESVGS-ANEVEGNVLHQTEPDMDSVKEMAAQETSLD-PVSDDEIEETE 840
Cdd:TIGR00927  722 EAEGTEDEGEIETGEEG-EEVEDEGEGEAEGKHEVETeGDRKETEHEGETEAEGKEDEDEGEIQAGEDgEMKGDEGAEGK 800

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  841 MQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDT-EDEKNTSLESEAQNVDKQEEGESKEESivchsvM 919
Cdd:TIGR00927  801 VEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAkQDEKGVDGGGGSDGGDSEEEEEEEEEE------E 874

                          250
                   ....*....|....*....
gi 2201812098  920 SESQVDKEALKENKKESEP 938
Cdd:TIGR00927  875 EEEEEEEEEEEEEEENEEP 893
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 823-1101 3.43e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 51.53  E-value: 3.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  823 AQETSLDPVSDDEIEETEmQTGDVSGkGEGNRIEDLEHNTTEDLKPKAEL---QTVQCSEETTGDTEDEK--NTSLESEA 897
Cdd:TIGR00927  622 AKVMALGDLSKGDVAEAE-HTGERTG-EEGERPTEAEGENGEESGGEAEQegeTETKGENESEGEIPAERkgEQEGEGEI 699

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  898 QNVDKQEEGESKEESIVCHSVMSESQVDKEALKENKKESEPADHQGDGftsveDADSSLALKAELDENVSEQLKLEGQAE 977
Cdd:TIGR00927  700 EAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEG-----EAEGKHEVETEGDRKETEHEGETEAEG 774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  978 EEQEDDGDaFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSgkiETSDTLTEDDSLQHKEGNE 1057
Cdd:TIGR00927  775 KEDEDEGE-IQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDE---TGEQELNAENQGEAKQDEK 850

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 2201812098 1058 SEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDL 1101
Cdd:TIGR00927  851 GVDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEEPL 894
PTZ00121 PTZ00121
MAEBL; Provisional
 763-1095 2.78e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.52  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  763 ELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNvlHQTEPDMDSVKEMAAQETSLDPVSDDEIEETEMQ 842
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA--EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  843 TGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEEttgdtedekntslESEAQNVDKQEEGESKEesivCHSVMSES 922
Cdd:PTZ00121  1663 AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE-------------AKKAEELKKKEAEEKKK----AEELKKAE 1725

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  923 QVDKEALKENKKESEPADHQGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDgdafdfDEDSEQTAETDEK 1002
Cdd:PTZ00121  1726 EENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD------EEDEKRRMEVDKK 1799

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098 1003 CDGEEVDAQS--EEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQ-HKEGNESEETELSQEEASA------LET 1073
Cdd:PTZ00121  1800 IKDIFDNFANiiEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEkHKFNKNNENGEDGNKEADFnkekdlKED 1879

                          330       340
                   ....*....|....*....|..
gi 2201812098 1074 DEKADVLADEDKASDPNEVEKE 1095
Cdd:PTZ00121  1880 DEEEIEEADEIEKIDKDDIERE 1901
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 918-1114 1.14e-03

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.06  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  918 VMSESQVDKEALKEnkkesepADHQGDgfTSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAfDFDEDSEQTA 997
Cdd:TIGR00927  624 VMALGDLSKGDVAE-------AEHTGE--RTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEG-EIPAERKGEQ 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  998 ETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNESEETElSQEEASALETDEKA 1077
Cdd:TIGR00927  694 EGEGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETE-GDRKETEHEGETEA 772

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2201812098 1078 DVLADEDK----ASDPNEVEKEPGEQDLESAGCSRAESKED 1114
Cdd:TIGR00927  773 EGKEDEDEgeiqAGEDGEMKGDEGAEGKVEHEGETEAGEKD 813
PTZ00121 PTZ00121
MAEBL; Provisional
 787-1094 1.57e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 1.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  787 AEKQEKASESVGSANEVEGN--VLHQTEPDMDSVKEMAAQETSLDPVSDDEIEETEmqtgDVSGKGEGNRIEdlEHNTTE 864
Cdd:PTZ00121  1232 AEEAKKDAEEAKKAEEERNNeeIRKFEEARMAHFARRQAAIKAEEARKADELKKAE----EKKKADEAKKAE--EKKKAD 1305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  865 DLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQNVDKQEEGESKEESIVCHSVMSESQVDKEALKENKKESEPADHQGD 944
Cdd:PTZ00121  1306 EAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  945 GFTSVEDADsSLALKAELDENVSEQLKLEGQAEEEQED-DGDAFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIR 1023
Cdd:PTZ00121  1386 KAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKKKADEaKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2201812098 1024 KTAQTGEAGEGSGKIETSDTL------TEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNEVEK 1094
Cdd:PTZ00121  1465 KAEEAKKADEAKKKAEEAKKAdeakkkAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK 1541
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 933-1105 2.26e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 41.89  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  933 KKESEPADHQGDGFTSVEDADSSLALKAELDENVSEQ-LKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQ 1011
Cdd:PRK13108   277 KGREAPGALRGSEYVVDEALEREPAELAAAAVASAASaVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRD 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098 1012 SEEDDRTNSVIRKTAQTGEAGEGSGkiETSDTLTEDDSLQHKEGNESEETELSQEEASALETDEKADVLADEDKASDPNE 1091
Cdd:PRK13108   357 GESTPAVEETSEADIEREQPGDLAG--QAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAV 434

                          170
                   ....*....|....
gi 2201812098 1092 VEKEPGEQDLESAG 1105
Cdd:PRK13108   435 AGPGDDPAEPDGIR 448
BMS1 COG5192
GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and ...
 681-1102 5.26e-03

GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and biogenesis];


Pssm-ID: 227519 [Multi-domain]  Cd Length: 1077  Bit Score: 40.88  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  681 CTGGTADKTGGDRAGEQNEV----GSAVQGQKMERDSTGLEGEESCESgapSDPNEEGGDQahiqpvssevgelvllEEQ 756
Cdd:COG5192    305 CPPPDADHGRRRRLSLKSKLiyspMSDIGGILKDKDRVYIEVPTSNFS---KDENSEAGEG----------------EKM 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  757 NTQEQTELKPAEKDGQEEVLIGNLEAcSDPAEKQEKASESVG--SANEVEGNVLHQTEPDMDsvkEMAAQETSLDPVSDD 834
Cdd:COG5192    366 KMQLQEIEQDPGVDGVGLQLFSNSDA-IDTVDRESSEIDNVGrkTRRQPTGKAIAEETSRED---ELSFDDSDVSTSDEN 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  835 EIEETEMQTGDVSGKGE-GNRIEDLEHNTTEDlkpkaelqtvqcseettgdtEDEKNTSLESEAQNVDKQEEGESKEESI 913
Cdd:COG5192    442 EDVDFTGKKGAINNEDEsDNEEVAFDSDSQFD--------------------ESEGNLRWKEGLASKLAYSQSGKRGRNI 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  914 VCHSVMsESQVDKEALKENKKESEPA--------DHQGDGFTSVEDADSSLALKAE-LDENVSEQL--KLEGQAEEEQED 982
Cdd:COG5192    502 QKIFYD-ESLSPEECIEEYKGESAKSsesdlvvqDEPEDFFDVSKVANESISSNHEkLMESEFEELkkKWSSLAQLKSRF 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  983 DGDA-FDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSgkietsdtlTEDDSLQHKEGNESEET 1061
Cdd:COG5192    581 QKDAtLDSIEGEEELIQDDEKGNFEDLEDEENSSDNEMEESRGSSVTAENEESA---------DEVDYETEREENARKKE 651

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2201812098 1062 ELSQEeasaLETDEKADvlaDEDKASDPNEVEKEPGEQDLE 1102
Cdd:COG5192    652 ELRGN----FELEERGD---PEKKDVDWYTEEKRKIEEQLK 685
MDN1 COG5271
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ...
 659-1105 5.61e-03

Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444083 [Multi-domain]  Cd Length: 1028  Bit Score: 40.77  E-value: 5.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  659 LEESAENKVTEVLEKTLVESKDCTGGTADKTGGDRAGEQNEVGSAVQGQKMERDSTGLEGEESCESGAPSDPNEEGGDQA 738
Cdd:COG5271    237 SEDAVAAADETLLADDDDTESAGATAEVGGTPDTDDEATDDADGLEAAEDDALDAELTAAQAADPESDDDADDSTLAALE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  739 HIQPVSSEVGELVLLEEQNTQEQTELKPAEKDGQEEVLIGNLEACSDPAEKQEKASESVGSANEVEGNVLHQTEPDMDSV 818
Cdd:COG5271    317 GAAEDTEIATADELAAADDEDDDDSAAEDAAEEAATAEDSAAEDTQDAEDEAAGEAADESEGADTDAAADEADAAADDSA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  819 KEMAAQETSLDPVSDDEIEETEMQTGDVSGKGEGNRIEDLEHNTTEDLKPKAELQTVQCSEETTGDTEDEKNTSLESEAQ 898
Cdd:COG5271    397 DDEEASADGGTSPTSDTDEEEEEADEDASAGETEDESTDVTSAEDDIATDEEADSLADEEEEAEAELDTEEDTESAEEDA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  899 NVDKQEEGESKEESIVCHSVMSESQVDKEALKENKKESEPADH-QGDGFTSVEDADSSLALKAELDENVSEQLKLEGQAE 977
Cdd:COG5271    477 DGDEATDEDDASDDGDEEEAEEDAEAEADSDELTAEETSADDGaDTDAAADPEDSDEDALEDETEGEENAPGSDQDADET 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  978 EEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQSEEDDRTNSVIRKTAQTGEAGEGSGKIETSDTLTEDDSLQHKEGNE 1057
Cdd:COG5271    557 DEPEATAEEDEPDEAEAETEDATENADADETEESADESEEAEASEDEAAEEEEADDDEADADADGAADEEETEEEAAEDE 636

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 2201812098 1058 SEETELSQEEASALETDEKADVLADEDKASDPNEVEKEPGEQDLESAG 1105
Cdd:COG5271    637 AAEPETDASEAADEDADAETEAEASADESEEEAEDESETSSEDAEEDA 684
PTZ00482 PTZ00482
membrane-attack complex/perforin (MACPF) Superfamily; Provisional
 975-1114 5.81e-03

membrane-attack complex/perforin (MACPF) Superfamily; Provisional


Pssm-ID: 240433 [Multi-domain]  Cd Length: 844  Bit Score: 41.00  E-value: 5.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  975 QAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDAQS--EEDDRTNSVIRKTAQTGEAGEgsgKIETSDTLTEDDSLQH 1052
Cdd:PTZ00482    82 QRKSLDDDDDDEFDFLYEDDEDDAGNATSGESSTDDDSllELPDRDEDADTQANNDQTNDF---DQDDSSNSQTDQGLKQ 158

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2201812098 1053 KEGNESEETELSQEEASALETDEKADVLADEDKASdpnevEKEPGEQDLESAGCSRAESKED 1114
Cdd:PTZ00482   159 SVNLSSAEKLIEEKKGQTENTFKFYNFGNDGEEAA-----AKDGGKSKSSDPGPLNDSDGQG 215
DNA_pol_phi pfam04931
DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7. ...
 947-1047 8.54e-03

DNA polymerase phi; This family includes the fifth essential DNA polymerase in yeast EC:2.7.7.7. Pol5p is localized exclusively to the nucleolus and binds near or at the enhancer region of rRNA-encoding DNA repeating units.


Pssm-ID: 461488  Cd Length: 765  Bit Score: 40.30  E-value: 8.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2201812098  947 TSVEDADSSLALKAELDENVSEQLKLEGQAEEEQEDDGDAFDFDEDSEQTAETDEKCDGEEVDaqseEDDRTNSVIRKTA 1026
Cdd:pfam04931  620 LDVLDARENPEGQQELFEDEDEDEEDDDEEEDDDDEDDEDSEEDDDEDDDDEDEEDDDDEDVD----EIDELRAKLAEAL 695

                           90       100
                   ....*....|....*....|.
gi 2201812098 1027 QTGEAGEGSGKIETSDTLTED 1047
Cdd:pfam04931  696 GEHGDDADDDDSDSDEDMDDE 716
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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