|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
542-655 |
6.91e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
:
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.52 E-value: 6.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 542 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 620
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 2217268312 621 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 655
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
783-839 |
2.44e-17 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 76.34 E-value: 2.44e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268312 783 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 839
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| ADAMTS_CR_3 super family |
cl41950 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
469-540 |
1.04e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
The actual alignment was detected with superfamily member pfam19236:
Pssm-ID: 437068 Cd Length: 115 Bit Score: 59.72 E-value: 1.04e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217268312 469 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 540
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
80-110 |
1.09e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
:
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.34 E-value: 1.09e-05
10 20 30
....*....|....*....|....*....|.
gi 2217268312 80 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 110
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
176-425 |
2.24e-05 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 176 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 252
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 253 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 323
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 324 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 398
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 2217268312 399 GESEQLRA--CSQAPCPPEQPDPRALQCA 425
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1_ADAMTS super family |
cl40597 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
730-779 |
5.16e-04 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
The actual alignment was detected with superfamily member pfam19030:
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 38.59 E-value: 5.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2217268312 730 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 779
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
542-655 |
6.91e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.52 E-value: 6.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 542 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 620
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 2217268312 621 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 655
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
783-839 |
2.44e-17 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 76.34 E-value: 2.44e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268312 783 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 839
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
469-540 |
1.04e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 59.72 E-value: 1.04e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217268312 469 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 540
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
80-110 |
1.09e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.34 E-value: 1.09e-05
10 20 30
....*....|....*....|....*....|.
gi 2217268312 80 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 110
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
176-425 |
2.24e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 176 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 252
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 253 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 323
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 324 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 398
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 2217268312 399 GESEQLRA--CSQAPCPPEQPDPRALQCA 425
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
730-779 |
5.16e-04 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 38.59 E-value: 5.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2217268312 730 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 779
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
783-839 |
5.90e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 38.72 E-value: 5.90e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268312 783 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 839
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
132-349 |
1.15e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 42.72 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 132 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 211
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 212 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 291
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217268312 292 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 349
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
81-107 |
1.69e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 37.01 E-value: 1.69e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ADAMTS_spacer1 |
pfam05986 |
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like ... |
542-655 |
6.91e-29 |
|
ADAM-TS Spacer 1; This domain represents the Spacer-1 region from the ADAM-TS and ADAM-TS-like proteins. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase) and is a subfamily of the metalloprotease family, sharing a high degree of sequence similarity and conserved domain organization among its members. Members of the ADAM-TS family have been implicated in a range of diseases. ADAM-TS-like proteins lack a metalloprotease domain. They resides in the ECM and have regulatory roles. Examples of ADAM-TS-like proteins are papilin and punctin.
Pssm-ID: 461796 Cd Length: 115 Bit Score: 111.52 E-value: 6.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 542 LVSGNLTdRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDP-PGSYRAGGTVFRYNRPPREe 620
Cdd:pfam05986 1 TVSGSFT-EGRAKGYVTFVTIPAGATHIHIVNRKPSFTHLAVKNVQGKYILNGKGSISLnPTYPSLLGTVLEYRRSLPA- 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 2217268312 621 gkGESLSAEGPTTQPVDVYMIFQEE---NPGVFYQYVI 655
Cdd:pfam05986 79 --LEELHAPGPTQEDLEIQVLRQYGkgtNPGITYEYFI 114
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
783-839 |
2.44e-17 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 76.34 E-value: 2.44e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268312 783 WEAGEWTSCSRSCGPGTQHRQLQCRQEfgGGGSSVPPERCGHLPRPNITQSCQLRLC 839
Cdd:pfam19030 1 WVAGPWGECSVTCGGGVQTRLVQCVQK--GGGSIVPDSECSAQKKPPETQSCNLKPC 55
|
|
| ADAMTS_CR_3 |
pfam19236 |
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ... |
469-540 |
1.04e-10 |
|
ADAMTS cysteine-rich domain; This cysteine rich domain is found in a variety of ADAMTS and ADAMTS-like endopeptidases widely spread in animals. It is a well-conserved cysteine-rich sequence containing 10 cysteine residues. ADAM-TS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) is closely related to the ADAM family (A Disintegrin and Metalloproteinase, pfam08516) and consists of at least 20 members sharing a high degree of sequence similarity and conserved domain organization. Members of the ADAMTS family have been implicated in a range of diseases.
Pssm-ID: 437068 Cd Length: 115 Bit Score: 59.72 E-value: 1.04e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2217268312 469 QGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAP------DICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTC 540
Cdd:pfam19236 38 QGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPredgtlSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTC 115
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
80-110 |
1.09e-05 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 43.34 E-value: 1.09e-05
10 20 30
....*....|....*....|....*....|.
gi 2217268312 80 WGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 110
Cdd:smart00209 1 WSEWSEWSPCSVTCGGGVQTRTRSCCSPPPQ 31
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
176-425 |
2.24e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 176 ARRSRLRDPIKPGMFGYGRVPfalplhrnrRHPRSPPRSELSLISSRGEEAIPSP---TPRAEPFSANGSPQTELPPTEL 252
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAP---------VDDRGDPRGPAPPSPLPPDTHAPDPpppSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 253 SVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRA---------QASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWA 323
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAarptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 324 SPQV-AGRRPDPFPSVPRGRGqqGQGPWGTGGTPHGPRLEPDPQHPGA----WLPLLSNGPHASSLWSLFAPSSPIPRCS 398
Cdd:PHA03247 2732 SPALpAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAgpprRLTRPAVASLSESRESLPSPWDPADPPA 2809
|
250 260
....*....|....*....|....*....
gi 2217268312 399 GESEQLRA--CSQAPCPPEQPDPRALQCA 425
Cdd:PHA03247 2810 AVLAPAAAlpPAASPAGPLPPPTSAQPTA 2838
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
127-449 |
1.12e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 127 ALLPRGQGPRPqtsPETLPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPgmfgygrVPFALPLHRNRR 206
Cdd:PHA03247 2616 PLPPDTHAPDP---PPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQASSPPQRPRR 2685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 207 HPRSPPRSELSLISSRgeeaiPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQ-----AEPLSPETAQTEVAPRTRPAP 281
Cdd:PHA03247 2686 RAARPTVGSLTSLADP-----PPPPPTPEPAPHALVSATPLPPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARP 2760
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 282 LRHH-------PRAQASGTEPPSPTHSLGEGGFFRAS----------------PQPRRPSSQGWASPQVAGRRPDPFPSV 338
Cdd:PHA03247 2761 PTTAgppapapPAAPAAGPPRRLTRPAVASLSESRESlpspwdpadppaavlaPAAALPPAASPAGPLPPPTSAQPTAPP 2840
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 339 PRGRGQQGQGPWGTGGTPHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPD 418
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920
|
330 340 350
....*....|....*....|....*....|.
gi 2217268312 419 PRALQCAAFNSQEfmgqlyQWEPFTEAPLLP 449
Cdd:PHA03247 2921 PQPPPPPQPQPPP------PPPPRPQPPLAP 2945
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
208-370 |
1.27e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 208 PRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPR 287
Cdd:PRK07764 597 GEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGA 676
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 288 AQASGTEPPSPTHSLGEGGFFRASPQPRRPssQGWASPQVAGRRPDPfPSVPRGRGQQGQGPWGTGGTPHGPRLEPDPQH 367
Cdd:PRK07764 677 APAAPPPAPAPAAPAAPAGAAPAQPAPAPA--ATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPLPPEPDDPPDPAG 753
|
...
gi 2217268312 368 PGA 370
Cdd:PRK07764 754 APA 756
|
|
| TSP1_ADAMTS |
pfam19030 |
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found ... |
730-779 |
5.16e-04 |
|
Thrombospondin type 1 domain; This subfamily of thrombospondin type 1 repeats are mainly found in ADAMTS proteins.
Pssm-ID: 465950 [Multi-domain] Cd Length: 55 Bit Score: 38.59 E-value: 5.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2217268312 730 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASpEPCHGTPC 779
Cdd:pfam19030 7 GECSVTCGGGVQTRLVQCVQKGGGSIVPDSECSAQKKPPET-QSCNLKPC 55
|
|
| TSP1 |
smart00209 |
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta. |
783-839 |
5.90e-04 |
|
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
Pssm-ID: 214559 [Multi-domain] Cd Length: 53 Bit Score: 38.72 E-value: 5.90e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 2217268312 783 WEAGEWTSCSRSCGPGTQHRQLQCRqefgGGGSSVPPERCGHLPRpnITQSCQLRLC 839
Cdd:smart00209 2 SEWSEWSPCSVTCGGGVQTRTRSCC----SPPPQNGGGPCTGEDV--ETRACNEQPC 52
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
132-349 |
1.15e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 42.72 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 132 GQGPRPQTSPETLPLYRTQSRGRGGPLRGPAShlgreeTQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 211
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMS------LEEVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 212 PRSElslissrgeeaiPSPTPRAEPFSANGSPQTELPPTELSvHTPSPQAEPLSPetaqtevAPRTRPAPLRHHPRAQas 291
Cdd:pfam09770 238 PQIQ------------QQQQPQQQPQQPQQHPGQGHPVTILQ-RPQSPQPDPAQP-------SIQPQAQQFHQQPPPV-- 295
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2217268312 292 gtePPSPTHSLgeggffrasPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGP 349
Cdd:pfam09770 296 ---PVQPTQIL---------QNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
133-425 |
1.57e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 133 QGPRPQTSPETL-PLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSP 211
Cdd:PHA03247 2681 QRPRRRAARPTVgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 212 PRSElSLISSRGEEAIPSPTPRAEPFSAnGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPR---TRPAPLRHHPRA 288
Cdd:PHA03247 2761 PTTA-GPPAPAPPAAPAAGPPRRLTRPA-VASLSESRESLPSPWDPADPPAAVLAPAAALPPAASpagPLPPPTSAQPTA 2838
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 289 QASGTEPPSPTHSLG----EGGFFRASPQPRRPSSQGWASPQVAGRRPdPFPSVPRGRGQQGQGPWG-----TGGTPHGP 359
Cdd:PHA03247 2839 PPPPPGPPPPSLPLGgsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRL-ARPAVSRSTESFALPPDQperppQPQAPPPP 2917
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217268312 360 RLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRALQCA 425
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| TSP_1 |
pfam00090 |
Thrombospondin type 1 domain; |
81-107 |
1.69e-03 |
|
Thrombospondin type 1 domain;
Pssm-ID: 459668 [Multi-domain] Cd Length: 49 Bit Score: 37.01 E-value: 1.69e-03
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
206-420 |
1.89e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 41.73 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 206 RHPRSPPRSELSLISSRGEEAIPSPTPRAEPfsangSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHH 285
Cdd:PRK14086 76 RELGRPIRIAITVDPSAGEPAPPPPHARRTS-----EPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 286 PRAQaSGTEPPSPthslgeggfFRASPQPRR---PSSQGWASPQVAGRRPDPF-PSVPRGRGQQGQgPWGTGGTPhgprl 361
Cdd:PRK14086 151 QRPE-PGAWPRAA---------DDYGWQQQRlgfPPRAPYASPASYAPEQERDrEPYDAGRPEYDQ-RRRDYDHP----- 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217268312 362 EPDPQHPGAW---LPLLSNG---PHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCP-PEQPDPR 420
Cdd:PRK14086 215 RPDWDRPRRDrtdRPEPPPGaghVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPgPGEPTAR 280
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
222-336 |
2.13e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 41.62 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 222 RGEEAIPSPTPRAEPFSANGSpqTELPPTElsvhTPSPQAEPLSPETAQTEVAPRTRPAPLRHH-PRAQASGTEPPSPTH 300
Cdd:PRK14951 383 RPEAAAPAAAPVAQAAAAPAP--AAAPAAA----ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAaPAAVALAPAPPAQAA 456
|
90 100 110
....*....|....*....|....*....|....*.
gi 2217268312 301 SLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFP 336
Cdd:PRK14951 457 PETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| TSP1_spondin |
pfam19028 |
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ... |
81-103 |
2.15e-03 |
|
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.
Pssm-ID: 465948 Cd Length: 52 Bit Score: 36.87 E-value: 2.15e-03
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
210-420 |
3.28e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 41.31 E-value: 3.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 210 SPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTE---LPPTELSVHTPSPQAEPLSPETAQtevAPRTRPAPLRHHP 286
Cdd:PHA03307 136 EMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalpLSSPEETARAPSSPPAEPPPSTPP---AAASPRPPRRSSP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217268312 287 RAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGPWGTG---------GTPH 357
Cdd:PHA03307 213 ISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSsrpgpasssSSPR 292
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2217268312 358 GPRLEPDPQHPGAwlPLLSNGPHASSLWSLFAPSS-PIPRCSGESEqlRACSQAPCPPEQPDPR 420
Cdd:PHA03307 293 ERSPSPSPSSPGS--GPAPSSPRASSSSSSSRESSsSSTSSSSESS--RGAAVSPGPSPSRSPS 352
|
|
| |
