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Conserved domains on  [gi|2462553665|ref|XP_054171307|]
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centrosomal protein of 112 kDa isoform X12 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-525 1.23e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   2 IKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADIN 81
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  82 LLKQEHALSASKAS---------SMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSE- 151
Cdd:COG1196   328 LEEELEELEEELEEleeeleeaeEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEe 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 152 LDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLR 231
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 232 EKQSKEflWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIEN----LEKQLRAANMEHENQIQEF 307
Cdd:COG1196   488 EAAARL--LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaALQNIVVEDDEVAAAAIEY 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 308 KKRD----AQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAE 383
Cdd:COG1196   566 LKAAkagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 384 temtlekanskLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVL 463
Cdd:COG1196   646 -----------LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462553665 464 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASlRQELEDTISSLKSQ 525
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLERE 775
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-525 1.23e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   2 IKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADIN 81
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  82 LLKQEHALSASKAS---------SMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSE- 151
Cdd:COG1196   328 LEEELEELEEELEEleeeleeaeEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEe 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 152 LDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLR 231
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 232 EKQSKEflWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIEN----LEKQLRAANMEHENQIQEF 307
Cdd:COG1196   488 EAAARL--LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaALQNIVVEDDEVAAAAIEY 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 308 KKRD----AQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAE 383
Cdd:COG1196   566 LKAAkagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 384 temtlekanskLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVL 463
Cdd:COG1196   646 -----------LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462553665 464 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASlRQELEDTISSLKSQ 525
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 100-539 3.26e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 3.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  100 ELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTR 179
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  180 VTEVQRLQAQQADAAlEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYE-QQIVELKL 258
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAK 1457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  259 EHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHEnqiQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQ 338
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  339 QLVELGLLREEEKQRATREHEivvnKLKAESEKMKIELKKTHAAETEMTLEKAnSKLKQIEKEYTQKLAKSSQIIAELQT 418
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAE----ELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  419 TiSSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRsnqVRCAEKKlqHKELESQEQITYIRQE 498
Cdd:PTZ00121  1610 E-EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK---IKAAEEA--KKAEEDKKKAEEAKKA 1683

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2462553665  499 YETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEE 539
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 12-331 2.50e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 2.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   12 LTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKydadinllkqEHALSA 91
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL----------SRQISA 730

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   92 SKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALK 171
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  172 EKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKvyAEMKEQMEKVEADLTRSKSLREKQSKEfLWQLEDIRQRYEQ 251
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESE-LEALLNERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  252 QIVELKL----------EHEQEKTHLLQQHNAEKDSLVRDHER------EIENLEKQLRA-ANMEHENQIQEFKKRDAQv 314
Cdd:TIGR02168  888 ALALLRSeleelseelrELESKRSELRRELEELREKLAQLELRleglevRIDNLQERLSEeYSLTLEEAEALENKIEDD- 966

                          330
                   ....*....|....*..
gi 2462553665  315 IADMEAQVHKLREELIN 331
Cdd:TIGR02168  967 EEEARRRLKRLENKIKE 983
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 226-491 7.80e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 7.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 226 RSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLV-RDHEREIENLEKQLraanmehENQI 304
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIyAEQERMAMEREREL-------ERIR 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 305 QEFKKRDAQVIADME--AQVHKLRE-ELINVNSQRKQQLVELGL-------LREEEKQRATREHEIVVNKLKAESEKMKI 374
Cdd:pfam17380 355 QEERKRELERIRQEEiaMEISRMRElERLQMERQQKNERVRQELeaarkvkILEEERQRKIQQQKVEMEQIRAEQEEARQ 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 375 ELKKTHAAETEMTLEkansKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIR 454
Cdd:pfam17380 435 REVRRLEEERAREME----RVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIE 510

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2462553665 455 DNDQAiKVLQDELENRSNQVRCAEKKLQHKELESQEQ 491
Cdd:pfam17380 511 EERKR-KLLEKEMEERQKAIYEEERRREAEEERRKQQ 546
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 191-503 1.64e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 191 ADAALEEFKRQVELNSEKVYAEMKEQMEKVeadltrskslREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKT----- 265
Cdd:NF033838   52 GNESQKEHAKEVESHLEKILSEIQKSLDKR----------KHTQNVALNKKLSDIKTEYLYELNVLKEKSEAELTsktkk 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 266 ------HLLQQHNAEKDSLVRDHEREIENLEKQLRAANME-HENQIQEFKKRDAQVIADMEAQVHKLREELINVN---SQ 335
Cdd:NF033838  122 eldaafEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEdRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEakePR 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 336 RKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEK----------EYTQK 405
Cdd:NF033838  202 DEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKrgvlgepatpDKKEN 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 406 LAKSSQIIAELQTTIS-SLKEEnsQQQLAAERRLQDVRQKFEDEKKQLIRD-NDQAIKVLQDELENRSNQVRCAEKKL-- 481
Cdd:NF033838  282 DAKSSDSSVGEETLPSpSLKPE--KKVAEAEKKVEEAKKKAKDQKEEDRRNyPTNTYKTLELEIAESDVKVKEAELELvk 359

                         330       340
                  ....*....|....*....|...
gi 2462553665 482 -QHKELESQEQITYIRQEYETKL 503
Cdd:NF033838  360 eEAKEPRNEEKIKQAKAKVESKK 382
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-525 1.23e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   2 IKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADIN 81
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  82 LLKQEHALSASKAS---------SMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSE- 151
Cdd:COG1196   328 LEEELEELEEELEEleeeleeaeEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEe 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 152 LDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLR 231
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 232 EKQSKEflWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIEN----LEKQLRAANMEHENQIQEF 307
Cdd:COG1196   488 EAAARL--LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAalaaALQNIVVEDDEVAAAAIEY 565

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 308 KKRD----AQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAE 383
Cdd:COG1196   566 LKAAkagrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGR 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 384 temtlekanskLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVL 463
Cdd:COG1196   646 -----------LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462553665 464 QDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASlRQELEDTISSLKSQ 525
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD-LEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 157-468 2.59e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.87  E-value: 2.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 157 EDTQKKIHKFEEALKEKEEQLTRVtEVQRLQAQQADAALEEFK-RQVELNSEKvYAEMKEQMEKVEADLTRSKSLREKQS 235
Cdd:COG1196   182 EATEENLERLEDILGELERQLEPL-ERQAEKAERYRELKEELKeLEAELLLLK-LRELEAELEELEAELEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 236 KEF-LWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEfKKRDAQV 314
Cdd:COG1196   260 AELaELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE-LEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 315 IADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSK 394
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462553665 395 LKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELE 468
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-532 3.47e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 3.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   2 IKELEARVQQLTGEAENSNLQRQKLIQEKAELErcyqitcSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQtKYDADIN 81
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAELAELE-------AELEELRLELEELELELEEAQAEEYELLAELA-RLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  82 LLKQEHALSASKASSMIEELEQNVcQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIyEKKAHDLQSELDKGKEDTQK 161
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELE-EELEELEEELEELEEELEEAEEELEEAEAELAEA-EEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 162 KIHKFEEALKEKEEQLTRVTEVQRLQA--QQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFL 239
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEalLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 240 WQLEDIRQ--RYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHE-REIENLEKQLRAANMEHENQIQEFKKRDAQVIA 316
Cdd:COG1196   464 LLAELLEEaaLLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 317 DMEAQVHKLRE------ELINVNSQRKQ--------QLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAA 382
Cdd:COG1196   544 LAAALQNIVVEddevaaAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 383 ETEMTLEKANSKLKQIEKEYTQKLAKS--SQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAI 460
Cdd:COG1196   624 GRTLVAARLEAALRRAVTLAGRLREVTleGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEE 703

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462553665 461 KVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKR 532
Cdd:COG1196   704 EEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-540 4.82e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 4.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   2 IKELEARVQQLTGEAENSnLQRQKLIQEKAELERCYQItcSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKyDADIN 81
Cdd:COG1196   195 LGELERQLEPLERQAEKA-ERYRELKEELKELEAELLL--LKLRELEAELEELEAELEELEAELEELEAELAEL-EAELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  82 LLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKShlkhiyekkahdlQSELDKGKEDTQK 161
Cdd:COG1196   271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE-------------LAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 162 KIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQskeflwQ 241
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE------A 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 242 LEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSlvrdhEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQ 321
Cdd:COG1196   412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEA-----AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 322 VHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKE 401
Cdd:COG1196   487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 402 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKL 481
Cdd:COG1196   567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2462553665 482 QHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEEL 540
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705
PTZ00121 PTZ00121
MAEBL; Provisional
 100-539 3.26e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 3.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  100 ELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTR 179
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  180 VTEVQRLQAQQADAAlEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYE-QQIVELKL 258
Cdd:PTZ00121  1379 KADAAKKKAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEaKKKAEEAK 1457

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  259 EHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHEnqiQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQ 338
Cdd:PTZ00121  1458 KAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  339 QLVELGLLREEEKQRATREHEivvnKLKAESEKMKIELKKTHAAETEMTLEKAnSKLKQIEKEYTQKLAKSSQIIAELQT 418
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAE----ELKKAEEKKKAEEAKKAEEDKNMALRKA-EEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  419 TiSSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRsnqVRCAEKKlqHKELESQEQITYIRQE 498
Cdd:PTZ00121  1610 E-EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK---IKAAEEA--KKAEEDKKKAEEAKKA 1683

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2462553665  499 YETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEE 539
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 12-331 2.50e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 2.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   12 LTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKydadinllkqEHALSA 91
Cdd:TIGR02168  661 ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL----------SRQISA 730

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   92 SKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALK 171
Cdd:TIGR02168  731 LRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  172 EKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKvyAEMKEQMEKVEADLTRSKSLREKQSKEfLWQLEDIRQRYEQ 251
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI--EELSEDIESLAAEIEELEELIEELESE-LEALLNERASLEE 887

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  252 QIVELKL----------EHEQEKTHLLQQHNAEKDSLVRDHER------EIENLEKQLRA-ANMEHENQIQEFKKRDAQv 314
Cdd:TIGR02168  888 ALALLRSeleelseelrELESKRSELRRELEELREKLAQLELRleglevRIDNLQERLSEeYSLTLEEAEALENKIEDD- 966

                          330
                   ....*....|....*..
gi 2462553665  315 IADMEAQVHKLREELIN 331
Cdd:TIGR02168  967 EEEARRRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 116-502 1.46e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 1.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  116 ELQRKQQLRDQENKFQMEKSHLKHIYEKKAhdlqSELDKGKEDTQKKihkfEEALKEKEEQLTRVTEVQRLQAQQADAAL 195
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKA----DEAKKKAEEAKKK----ADAAKKKAEEAKKAAEAAKAEAEAAADEA 1359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  196 EEFKRQVELnsekvyAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEqqivELKLEHEQEKthllqqhNAEK 275
Cdd:PTZ00121  1360 EAAEEKAEA------AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKAD----ELKKAAAAKK-------KADE 1422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  276 DSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQlvELGLLREEEKQRAT 355
Cdd:PTZ00121  1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKAD--EAKKKAEEAKKKAD 1500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  356 REHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAE 435
Cdd:PTZ00121  1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL 1580

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462553665  436 RRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETK 502
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK 1647
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 171-391 1.55e-05

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 47.90  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 171 KEKEEQLTRVTEVQRLQAQQADAALEEFKRQVelnsEKVYAEMKEQMEKVEAdltRSKSLREKQskeflwqlediRQRYE 250
Cdd:PRK00409  515 KEKLNELIASLEELERELEQKAEEAEALLKEA----EKLKEELEEKKEKLQE---EEDKLLEEA-----------EKEAQ 576

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 251 QQIVELKLEHEQEKTHLLQQHNAEKDSLVrdhEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLRE--E 328
Cdd:PRK00409  577 QAIKEAKKEADEIIKELRQLQKGGYASVK---AHELIEARKRLNKANEKKEKKKKKQKEKQEELKVGDEVKYLSLGQkgE 653

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462553665 329 LINVNSQRKQQL--------VELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKA 391
Cdd:PRK00409  654 VLSIPDDKEAIVqagimkmkVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSLELDLRGMRYEEALERLDKY 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1-468 1.76e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.62  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   1 MIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADI 80
Cdd:COG1196   310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  81 NLLKQEhalsaskassmiEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQ 160
Cdd:COG1196   390 EALRAA------------AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 161 KKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEAD-LTRSKSLREKQSKEFL 239
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRgLAGAVAVLIGVEAAYE 537

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 240 WQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNA--------EKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRD 311
Cdd:COG1196   538 AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 312 AQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKA 391
Cdd:COG1196   618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462553665 392 nsklKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELE 468
Cdd:COG1196   698 ----ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-502 5.91e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.20  E-value: 5.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  207 EKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQivelkleheQEKTHLLQQHNAEKDSLVRDHEREI 286
Cdd:TIGR02168  192 EDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL---------REELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  287 ENLEKQL---RAANMEHENQIQEFKKR---DAQVIADMEAQVHKLREELINVNSQRKQQLVELGLL--REEEKQRATREH 358
Cdd:TIGR02168  263 QELEEKLeelRLEVSELEEEIEELQKElyaLANEISRLEQQKQILRERLANLERQLEELEAQLEELesKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  359 EIVVNKLKAESEKMKIELKkthaaETEMTLEKANSKLKQIEKEYTQKLAKSSQI---IAELQTTISSLKEENSQQQLAAE 435
Cdd:TIGR02168  343 EEKLEELKEELESLEAELE-----ELEAELEELESRLEELEEQLETLRSKVAQLelqIASLNNEIERLEARLERLEDRRE 417

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  436 RRLQ---DVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETK 502
Cdd:TIGR02168  418 RLQQeieELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
PTZ00121 PTZ00121
MAEBL; Provisional
 84-504 6.12e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 6.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   84 KQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKhiyEKKAHDLQSELDKGKEDTQKK- 162
Cdd:PTZ00121  1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE---KAEAAEKKKEEAKKKADAAKKk 1386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  163 ---IHKFEEALKEKEEQLTRVTEVQRLQAQQADAalEEFKRQVElNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFL 239
Cdd:PTZ00121  1387 aeeKKKADEAKKKAEEDKKKADELKKAAAAKKKA--DEAKKKAE-EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK 1463

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  240 WQLEDIRQRYE--------QQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRD 311
Cdd:PTZ00121  1464 KKAEEAKKADEakkkaeeaKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAE 1543

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  312 AQVIADMEAQVHKLR--EELINVNSQRKQQ------LVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAE 383
Cdd:PTZ00121  1544 EKKKADELKKAEELKkaEEKKKAEEAKKAEedknmaLRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  384 TEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTI-------------------SSLKEENSQQQLAAERRLQDVRQK 444
Cdd:PTZ00121  1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKikaaeeakkaeedkkkaeeAKKAEEDEKKAAEALKKEAEEAKK 1703

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  445 FEDEKKQLIRDNDQAIKVLQDELENRSNQvrcaeKKLQHKELESQEQITYIRQEYETKLK 504
Cdd:PTZ00121  1704 AEELKKKEAEEKKKAEELKKAEEENKIKA-----EEAKKEAEEDKKKAEEAKKDEEEKKK 1758
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 226-491 7.80e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 7.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 226 RSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLV-RDHEREIENLEKQLraanmehENQI 304
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIyAEQERMAMEREREL-------ERIR 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 305 QEFKKRDAQVIADME--AQVHKLRE-ELINVNSQRKQQLVELGL-------LREEEKQRATREHEIVVNKLKAESEKMKI 374
Cdd:pfam17380 355 QEERKRELERIRQEEiaMEISRMRElERLQMERQQKNERVRQELeaarkvkILEEERQRKIQQQKVEMEQIRAEQEEARQ 434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 375 ELKKTHAAETEMTLEkansKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIR 454
Cdd:pfam17380 435 REVRRLEEERAREME----RVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIE 510

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2462553665 455 DNDQAiKVLQDELENRSNQVRCAEKKLQHKELESQEQ 491
Cdd:pfam17380 511 EERKR-KLLEKEMEERQKAIYEEERRREAEEERRKQQ 546
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 205-529 1.33e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  205 NSEKVYAEMKEQMEKVEADLTRSKSLREKQSkEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDslVRDHER 284
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELE-ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER--IAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  285 EIENLEKQlRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREeekqratrehEIVVNK 364
Cdd:TIGR02168  755 ELTELEAE-IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE----------EAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  365 LKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEytqkLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQK 444
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEALALLRSELEEL 899

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  445 FEDekkqlIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMP-----ASLRQELEDTI 519
Cdd:TIGR02168  900 SEE-----LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEAlenkiEDDEEEARRRL 974

                          330
                   ....*....|
gi 2462553665  520 SSLKSQVNFL 529
Cdd:TIGR02168  975 KRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 7-546 1.81e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665    7 ARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYeQNMKLLQTKYDADINLLKQE 86
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL-YALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   87 HALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHlkhiyeKKAHDLQSELDKGKEDTQKKIHKF 166
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL------EELEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  167 EEALKEKEEQLtrvtEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIR 246
Cdd:TIGR02168  385 RSKVAQLELQI----ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  247 QRYE--QQIVELKLEHEQEKTHLLQQHNAEKDSLVRDhEREIENLEKQLRAAnMEHENQIQEFKKRDAQVI---ADMEAQ 321
Cdd:TIGR02168  461 EALEelREELEEAEQALDAAERELAQLQARLDSLERL-QENLEGFSEGVKAL-LKNQSGLSGILGVLSELIsvdEGYEAA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  322 VHKLREELIN--VNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEK--------- 390
Cdd:TIGR02168  539 IEAALGGRLQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKfdpklrkal 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  391 ---------------ANSKLKQIEKEYT-----------------------QKLAKSSQIIAELQTTISSL--KEENSQQ 430
Cdd:TIGR02168  619 syllggvlvvddldnALELAKKLRPGYRivtldgdlvrpggvitggsaktnSSILERRREIEELEEKIEELeeKIAELEK 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  431 QLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYiRQEYETKLKGLMPA- 509
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE-IEELEERLEEAEEEl 777

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2462553665  510 ----SLRQELEDTISSLKSQVNFLQKRASILQEELTTYQGR 546
Cdd:TIGR02168  778 aeaeAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
189-426 2.22e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  189 QQADAALEEFKRqvelnsekvYAEMKEQMEKVEADLTRSKSLREKQSKefLWQLEDIRQRYEQQIVELKLEHEQEKTHLL 268
Cdd:COG4913    225 EAADALVEHFDD---------LERAHEALEDAREQIELLEPIRELAER--YAAARERLAELEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  269 QQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQ---QLVELGL 345
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARleaLLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  346 LREEEKQRATREHEivvnKLKAESEKMKIELKKTHAAETEM--TLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSL 423
Cdd:COG4913    374 PLPASAEEFAALRA----EAAALLEALEEELEALEEALAEAeaALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL 449


                   ...
gi 2462553665  424 KEE 426
Cdd:COG4913    450 AEA 452
PTZ00121 PTZ00121
MAEBL; Provisional
 56-469 2.38e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   56 KEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEElEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKS 135
Cdd:PTZ00121  1424 KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE-AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  136 HLKHIYEKKAHDLQSELDKGKEDTQKKIHKfeealKEKEEQLTRVTEVQRLqaqqadaalEEFKRQVELNSEKvyaEMKE 215
Cdd:PTZ00121  1503 KKAAEAKKKADEAKKAEEAKKADEAKKAEE-----AKKADEAKKAEEKKKA---------DELKKAEELKKAE---EKKK 1565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  216 QMEKVEADLTRSKSLRekqskeflwQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQlra 295
Cdd:PTZ00121  1566 AEEAKKAEEDKNMALR---------KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK--- 1633

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  296 aNMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIE 375
Cdd:PTZ00121  1634 -KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  376 LKKTHAAETEMTLEKANSKLKQIEK--EYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLI 453
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKR 1792

                          410
                   ....*....|....*..
gi 2462553665  454 R-DNDQAIKVLQDELEN 469
Cdd:PTZ00121  1793 RmEVDKKIKDIFDNFAN 1809
PTZ00121 PTZ00121
MAEBL; Provisional
 107-411 2.38e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  107 QLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEAlKEKEEQLTRVTEVQRL 186
Cdd:PTZ00121  1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA-KIKAEELKKAEEEKKK 1634

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  187 QAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQ---IVELKLEHEQE 263
Cdd:PTZ00121  1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakkAEELKKKEAEE 1714

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  264 KTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHEnqiQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVEL 343
Cdd:PTZ00121  1715 KKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD---EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEK 1791

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462553665  344 GLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQ 411
Cdd:PTZ00121  1792 RRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE 1859
PRK12704 PRK12704
phosphodiesterase; Provisional
 109-263 2.56e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 109 KQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQA 188
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKRE 109

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462553665 189 QQADAALEEFKRQvELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLwqLEDIRQRYEQQIVELKLEHEQE 263
Cdd:PRK12704  110 EELEKKEKELEQK-QQELEKKEEELEELIEEQLQELERISGLTAEEAKEIL--LEKVEEEARHEAAVLIKEIEEE 181
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 146-508 4.75e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 4.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 146 HDLQSELDKGKEDTQKKIHKFE-EALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVEL--NSEKVYAEMKEQMEKVEA 222
Cdd:pfam17380 276 HIVQHQKAVSERQQQEKFEKMEqERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIyaEQERMAMERERELERIRQ 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 223 DlTRSKSLREKQSKEFLWQLEDIRQryeqqIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHEN 302
Cdd:pfam17380 356 E-ERKRELERIRQEEIAMEISRMRE-----LERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQ 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 303 QiqEFKKRDAQVIADMEA-QVHKLREElinvNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHA 381
Cdd:pfam17380 430 E--EARQREVRRLEEERArEMERVRLE----EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE 503

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 382 AETEMTLEKANSKLKQIEKEYTQKlakssqIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLirdndqaik 461
Cdd:pfam17380 504 RKQAMIEEERKRKLLEKEMEERQK------AIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRL--------- 568

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 2462553665 462 vlqDELENRSNQVR-CAEKKLQHKELESQEQITYIRQEYETKLKGLMP 508
Cdd:pfam17380 569 ---EAMEREREMMRqIVESEKARAEYEATTPITTIKPIYRPRISEYQP 613
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 93-233 6.01e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.89  E-value: 6.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  93 KASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQ-MEKSHLKhiYEKKAHDLQSELDKGKEDTQKKIHK-FEEAL 170
Cdd:PRK00409  506 EAKKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKeAEKLKEE--LEEKKEKLQEEEDKLLEEAEKEAQQaIKEAK 583

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462553665 171 KEKEEQLTRVTEVQRLQ-----AQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREK 233
Cdd:PRK00409  584 KEADEIIKELRQLQKGGyasvkAHELIEARKRLNKANEKKEKKKKKQKEKQEELKVGDEVKYLSLGQK 651
PRK01156 PRK01156
chromosome segregation protein; Provisional
 12-498 1.04e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  12 LTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKydadiNLLKQEHALSA 91
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK-----NRYESEIKTAE 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  92 SKAsSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHiYEKKAHDLQSELDKGKEDtqkkIHKFEEALK 171
Cdd:PRK01156  263 SDL-SMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIEN-KKQILSNIDAEINKYHAI----IKKLSVLQK 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 172 EKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSekvYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQ 251
Cdd:PRK01156  337 DYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS---IESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNE 413

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 252 QIVELkleheQEKTHLLQQHNAEKDSLvRDHEREIENLEKQLRAANM-------EHENQIQEFKKRDAQVIADMEAQVHK 324
Cdd:PRK01156  414 INVKL-----QDISSKVSSLNQRIRAL-RENLDELSRNMEMLNGQSVcpvcgttLGEEKSNHIINHYNEKKSRLEEKIRE 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 325 LREELINVNSQRKQQLVELGLLREEEKQRATREHEIvVNKLKAESEKMKI---ELKKTHAAETEMTLEKANSKLKQIEKE 401
Cdd:PRK01156  488 IEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNK-IESARADLEDIKIkinELKDKHDKYEEIKNRYKSLKLEDLDSK 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 402 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQlirdNDQAIKVLQDELENRSNQVRCAEKKL 481
Cdd:PRK01156  567 RTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSY----IDKSIREIENEANNLNNKYNEIQENK 642

                         490
                  ....*....|....*..
gi 2462553665 482 QHKElESQEQITYIRQE 498
Cdd:PRK01156  643 ILIE-KLRGKIDNYKKQ 658
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 97-542 1.56e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   97 MIEELEQNVCQLKQQLQES-ELQRKQQ---------LRDQENKFQMEKSHLKHIYEKKAhdlQSELDKgKEDTQKKIHKF 166
Cdd:pfam15921   79 VLEEYSHQVKDLQRRLNESnELHEKQKfylrqsvidLQTKLQEMQMERDAMADIRRRES---QSQEDL-RNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  167 EEALKEKEEQL----TRVTEVQRLQAQQaDAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQL 242
Cdd:pfam15921  155 EAAKCLKEDMLedsnTQIEQLRKMMLSH-EGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  243 EDIRQR---YEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEhENQIQefkkrdaqviadme 319
Cdd:pfam15921  234 SYLKGRifpVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQ-ANSIQ-------------- 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  320 AQVHKLREELINVNSQRKQQLVELgllreeekqratrehEIVVNKLKAESEKMKiELKKTHAAETEMTLEKANSKLKQIE 399
Cdd:pfam15921  299 SQLEIIQEQARNQNSMYMRQLSDL---------------ESTVSQLRSELREAK-RMYEDKIEELEKQLVLANSELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  400 KEYTQKLAKSSQIIAELQTTISSLkeensqqqlaaERRLQDVRQKFEDEKKQLIRDNDQAIKV--LQDELENRSNQVRCA 477
Cdd:pfam15921  363 TERDQFSQESGNLDDQLQKLLADL-----------HKREKELSLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRL 431

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462553665  478 EKKLQHKELESQEQITYIRQEYETKLKGLMP-ASLRQELEDTISSLKSQVNFLQKRASILQEELTT 542
Cdd:pfam15921  432 EALLKAMKSECQGQMERQMAAIQGKNESLEKvSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT 497
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 191-503 1.64e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 191 ADAALEEFKRQVELNSEKVYAEMKEQMEKVeadltrskslREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKT----- 265
Cdd:NF033838   52 GNESQKEHAKEVESHLEKILSEIQKSLDKR----------KHTQNVALNKKLSDIKTEYLYELNVLKEKSEAELTsktkk 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 266 ------HLLQQHNAEKDSLVRDHEREIENLEKQLRAANME-HENQIQEFKKRDAQVIADMEAQVHKLREELINVN---SQ 335
Cdd:NF033838  122 eldaafEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEdRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEakePR 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 336 RKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEK----------EYTQK 405
Cdd:NF033838  202 DEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKrgvlgepatpDKKEN 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 406 LAKSSQIIAELQTTIS-SLKEEnsQQQLAAERRLQDVRQKFEDEKKQLIRD-NDQAIKVLQDELENRSNQVRCAEKKL-- 481
Cdd:NF033838  282 DAKSSDSSVGEETLPSpSLKPE--KKVAEAEKKVEEAKKKAKDQKEEDRRNyPTNTYKTLELEIAESDVKVKEAELELvk 359

                         330       340
                  ....*....|....*....|...
gi 2462553665 482 -QHKELESQEQITYIRQEYETKL 503
Cdd:NF033838  360 eEAKEPRNEEKIKQAKAKVESKK 382
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1-267 2.29e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.04  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   1 MIKELEARVQQLTgEAENSNLQR-QKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLqtkydad 79
Cdd:PLN02939  136 MIQNAEKNILLLN-QARLQALEDlEKILTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLR------- 207

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  80 iNLLKQEHALSASKASSMIEEL----EQNVcQLKQQLQESELQRKQQLRDQENKFQMEKSHlkHIYEKKAHDLQSELDKG 155
Cdd:PLN02939  208 -NELLIRGATEGLCVHSLSKELdvlkEENM-LLKDDIQFLKAELIEVAETEERVFKLEKER--SLLDASLRELESKFIVA 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 156 KEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALE---EFKRQVE-----LNSEKVYAEMKEQMEKVEADLTRS 227
Cdd:PLN02939  284 QEDVSKLSPLQYDCWWEKVENLQDLLDRATNQVEKAALVLDqnqDLRDKVDkleasLKEANVSKFSSYKVELLQQKLKLL 363

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2462553665 228 KSLREKQSKEFLWQLedirQRYEQQIVEL-----KLEHEQEKTHL 267
Cdd:PLN02939  364 EERLQASDHEIHSYI----QLYQESIKEFqdtlsKLKEESKKRSL 404
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
148-366 2.41e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.77  E-value: 2.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 148 LQSELDKGKEDTQKKIHKFEEALKEKEEQLtrvtevqrlqaQQADAALEEFKRQ---VELNSE-----KVYAEMKEQMEK 219
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKEL-----------EEAEAALEEFRQKnglVDLSEEaklllQQLSELESQLAE 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 220 VEADLTRSKSLR---EKQSKEFLWQLEDIR-----QRYEQQIVELKLEHEQEKTHLLQQHNAekdslVRDHEREIENLEK 291
Cdd:COG3206   231 ARAELAEAEARLaalRAQLGSGPDALPELLqspviQQLRAQLAELEAELAELSARYTPNHPD-----VIALRAQIAALRA 305

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462553665 292 QLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRkQQLVELgllrEEEKQRATREHEIVVNKLK 366
Cdd:COG3206   306 QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELE-AELRRL----EREVEVARELYESLLQRLE 375
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 195-403 3.84e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 39.91  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 195 LEEFKRQVELNSEKVYAEMKEQMEKVEadltrskslrekqskeflwQLEDIRQRYEQQIVELK--------LEHEQEKTH 266
Cdd:PRK05771   84 LEELIKDVEEELEKIEKEIKELEEEIS-------------------ELENEIKELEQEIERLEpwgnfdldLSLLLGFKY 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 267 LlqqhnaekdsLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELiNVNSQRKQQLVELGLL 346
Cdd:PRK05771  145 V----------SVFVGTVPEDKLEELKLESDVENVEYISTDKGYVYVVVVVLKELSDEVEEEL-KKLGFERLELEEEGTP 213

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462553665 347 RE------EEKQRATREHEIVVNKLKAESEKMKIELKKTHaAETEMTLEKANSKLKQIEKEYT 403
Cdd:PRK05771  214 SElireikEELEEIEKERESLLEELKELAKKYLEELLALY-EYLEIELERAEALSKFLKTDKT 275
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 361-544 4.22e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 39.91  E-value: 4.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 361 VVNKLKAESEKMKI---ELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKssqiIAELQTTISSLKEENSQQQ------ 431
Cdd:PRK05771   58 ALDKLRSYLPKLNPlreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEE----ISELENEIKELEQEIERLEpwgnfd 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 432 --LAAERRLQDVRQKF----EDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKg 505
Cdd:PRK05771  134 ldLSLLLGFKYVSVFVgtvpEDKLEELKLESDVENVEYISTDKGYVYVVVVVLKELSDEVEEELKKLGFERLELEEEGT- 212

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2462553665 506 lmPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQ 544
Cdd:PRK05771  213 --PSELIREIKEELEEIEKERESLLEELKELAKKYLEEL 249
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 259-543 4.40e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.05  E-value: 4.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  259 EHEQEKTHLLQQHNAEKDSLvRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREelinvnSQRKQ 338
Cdd:TIGR02169  674 AELQRLRERLEGLKRELSSL-QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE------LEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  339 QLVELGLLREEEKQRatreheivvnKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQT 418
Cdd:TIGR02169  747 SSLEQEIENVKSELK----------ELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLRE 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  419 TISSLKEENSQQQLAAERRlqdvrqkfeDEKKQLIRDNDQAIKVLQDELEN-----RSNQVRCAEKKLQHKELESQ-EQI 492
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEI---------QELQEQRIDLKEQIKSIEKEIENlngkkEELEEELEELEAALRDLESRlGDL 887

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2462553665  493 TYIRQEYETKLKGLMPAslRQELEDTISSLKSQVNFLQKRASILQEELTTY 543
Cdd:TIGR02169  888 KKERDELEAQLRELERK--IEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 283-544 4.69e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.92  E-value: 4.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 283 EREIENLEKQLRAAnMEHENQIQEFKKRDAQVIAdmeAQVHKLREELINVNSQRKQQLVELgllREEEKQRATREHEIVV 362
Cdd:COG1196   199 ERQLEPLERQAEKA-ERYRELKEELKELEAELLL---LKLRELEAELEELEAELEELEAEL---EELEAELAELEAELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 363 NKLKAESEKMKIELKKTHAAETEMTLEKANSKL---KQIEKEYTQKLAKSSQIIAELQTTISSLKE---ENSQQQLAAER 436
Cdd:COG1196   272 LRLELEELELELEEAQAEEYELLAELARLEQDIarlEERRRELEERLEELEEELAELEEELEELEEeleELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 437 RLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQvrcAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELE 516
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL---LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE 428

                         250       260
                  ....*....|....*....|....*...
gi 2462553665 517 DTISSLKSQVNFLQKRASILQEELTTYQ 544
Cdd:COG1196   429 ALAELEEEEEEEEEALEEAAEEEAELEE 456
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
316-546 4.75e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 39.61  E-value: 4.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 316 ADMEAQVHKLREELiNVNSQRKQQLVELGLlREEEKQRATReheiVVNKLKAESEKMKIELKKTHAAET----EMTLEKA 391
Cdd:COG3206   114 ASREAAIERLRKNL-TVEPVKGSNVIEISY-TSPDPELAAA----VANALAEAYLEQNLELRREEARKAleflEEQLPEL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 392 NSKLKQIEKEYTQKLAKSSQIIAELQTTISSLK-EENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENR 470
Cdd:COG3206   188 RKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQlSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQ 267

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462553665 471 SNQvRCAEKKLQHKELESQEQITYIR-QEYETKLKGLMpASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQGR 546
Cdd:COG3206   268 LRA-QLAELEAELAELSARYTPNHPDvIALRAQIAALR-AQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR 342
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-284 5.36e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 5.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665    2 IKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHlvndYEQNMKLLQTKYDadin 81
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI----LRERLANLERQLE---- 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   82 llkqehalsaskassMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLkhiyeKKAHDLQSELDKGKEDTQK 161
Cdd:TIGR02168  320 ---------------ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-----EELEAELEELESRLEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  162 KIHKFEEALKEKEEQLtrvtEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQ 241
Cdd:TIGR02168  380 QLETLRSKVAQLELQI----ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 2462553665  242 LEDIRQRYE--QQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHER 284
Cdd:TIGR02168  456 LERLEEALEelREELEEAEQALDAAERELAQLQARLDSLERLQEN 500
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
6-526 5.44e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 39.66  E-value: 5.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665   6 EARVQQLTGEAENSNLQRQKLIQEKAELERcyqITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQ 85
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELP---ELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIREL 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  86 EHALSASKASsmIEELEQNVCQLKQQLQESELQRK-QQLRDQENKFQMEKSHLKHIYEKKAHDLQ-------------SE 151
Cdd:PRK03918  265 EERIEELKKE--IEELEEKVKELKELKEKAEEYIKlSEFYEEYLDELREIEKRLSRLEEEINGIEerikeleekeerlEE 342

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 152 LDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVElNSEKVYAEMKEQMEKVEADLTRSKSlR 231
Cdd:PRK03918  343 LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELE-ELEKAKEEIEEEISKITARIGELKK-E 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 232 EKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEkthLLQQHNAEKDSlVRDHEREIENLEKQLRAANMEHENQIQEFKKRD 311
Cdd:PRK03918  421 IKELKKAIEELKKAKGKCPVCGRELTEEHRKE---LLEEYTAELKR-IEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 312 AQviadmeaqvHKLREELINVnsqrKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHA-----AETEM 386
Cdd:PRK03918  497 KL---------KELAEQLKEL----EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEElkkklAELEK 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665 387 TLEKANSKLKQIEKEYTQKLAKSsqiIAELQTTISSLKE--ENSQQQLAAERRLQDVRQKFEDEKKQL--IRDNDQAIKV 462
Cdd:PRK03918  564 KLDELEEELAELLKELEELGFES---VEELEERLKELEPfyNEYLELKDAEKELEREEKELKKLEEELdkAFEELAETEK 640

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462553665 463 LQDELENRSNQVRCAEKKLQHKELEsqEQITYIRQEYETKLKGLMPA-SLRQELEDTISSLKSQV 526
Cdd:PRK03918  641 RLEELRKELEELEKKYSEEEYEELR--EEYLELSRELAGLRAELEELeKRREEIKKTLEKLKEEL 703
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 275-527 9.67e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 38.87  E-value: 9.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  275 KDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRA 354
Cdd:PTZ00108   997 KEYLLGKLERELARLSNKVRFIKHVINGELVITNAKKKDLVKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADDE 1076

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  355 TREHEIV--------------------VNKLKAESEKMKIELKKTHAAETE-MTLEKANSKLKQIEKEYTQKLAKSSQII 413
Cdd:PTZ00108  1077 DDEEELGaavsydyllsmpiwsltkekVEKLNAELEKKEKELEKLKNTTPKdMWLEDLDKFEEALEEQEEVEEKEIAKEQ 1156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462553665  414 AELQTTISSLKEENSQQQLAAERRlqdvrqkfedeKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQIT 493
Cdd:PTZ00108  1157 RLKSKTKGKASKLRKPKLKKKEKK-----------KKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQ 1225

                          250       260       270
                   ....*....|....*....|....*....|....
gi 2462553665  494 YIRQEYETKLKGlmPASLRQELEDTISSLKSQVN 527
Cdd:PTZ00108  1226 EDDEEQKTKPKK--SSVKRLKSKKNNSSKSSEDN 1257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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